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compositionComposition:AZELNIDIPINE-16MG
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Prescription Medicine
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Uniaz 16 Tablet is used to treat hypertension (high blood pressure). It contains Azelnidipine, which acts by relaxing the blood vessels. It may cause common side effects such as headaches, dizziness, swelling, and weakness. Before starting Uniaz 16 Tablet , let your doctor know if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

AZELNIDIPINE-16MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Uniaz 16 Tablet

This medicine, known as Uniaz 16 Tablet , is an oral prescription medicine primarily used to treat high blood pressure (hypertension). By lowering elevated blood pressure, it helps reduce the risk of serious cardiovascular events like strokes and heart attacks. Your doctor may prescribe it alone or alongside other blood pressure-lowering medicines.

To get the best results, you should take Uniaz 16 Tablet consistently at the same time every day as directed by your doctor. It can be taken with or without food, but keeping a regular routine helps maintain steady levels of the medicine in your body. Combining this medicine with a low-salt diet, regular moderate exercise, and stress management can significantly improve your blood pressure control.

Most people tolerate this medicine well, though some may experience mild side effects like headaches, mild dizziness, or swelling in the ankles. If you experience serious symptoms such as a very slow or fast heartbeat, chest pain, or a severe allergic reaction, contact your doctor immediately.

Before starting Uniaz 16 Tablet , tell your healthcare provider if you have a history of liver disease, kidney problems, or severe heart conditions. Do not take this medicine if you have severe liver damage, are pregnant, or are planning to become pregnant.
Avoid drinking alcohol while taking this medicine, as it can cause your blood pressure to drop too low, making you feel dizzy or faint. Let your doctor know if you are breastfeeding or if you are an older adult, as your dose may need to be adjusted carefully because older adults may clear the medicine more slowly and can be more sensitive to blood pressure drops, increasing the risk of dizziness and falls.

The safety and effectiveness of Uniaz 16 Tablet have not been established in children. If you have moderate kidney problems, your doctor will usually monitor your response carefully and decide whether any dose adjustment is needed based on your individual condition.

Uses of Uniaz 16 Tablet

Your doctor may prescribe Uniaz 16 Tablet for the following reasons:

  • High blood pressure (Hypertension): This medicine helps relax the blood vessels so that blood can flow more easily, which lowers overall blood pressure and reduces the workload on your heart.
  • Prevention of heart complications: By keeping your blood pressure within a healthy range, this medicine helps lower your long-term risk of experiencing a stroke, heart attack, or other serious cardiovascular issues.

Key Benefits

Managing high blood pressure is essential for your long-term health. This medicine offers several clinical benefits to help you stay well:

  • Gradual and steady blood pressure control: Unlike some older medicines that can cause sudden drops in blood pressure, this medicine works gradually. This steady action helps prevent sudden dizziness or a racing heart.
  • Long-lasting protection: A single daily dose provides consistent, 24-hour control of your blood pressure, ensuring you are protected throughout the day and night.
  • Protects vital organs: By keeping your blood pressure stable, it reduces the constant strain on your blood vessels, which helps protect your heart, kidneys, and brain from damage over time.
Side effects of Uniaz 16 Tablet
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Stay hydrated by drinking plenty of water.
  • Limit caffeine, nicotine, and alcohol.
  • Avoid processed foods, excess salt, and sugary drinks.
  • Manage stress through relaxation techniques.
  • Exercise regularly and maintain a healthy weight.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Directions for Use

  • Uniaz 16 Tablet can be taken after breakfast or as advised by your doctor.
  • It is usually taken once daily, or as prescribed by your doctor.
  • Swallow Uniaz 16 Tablet as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Uniaz 16 Tablet Works

Uniaz 16 Tablet belongs to a class of medicines called calcium channel blockers. To understand how it works, imagine your blood vessels as flexible pipes. When these pipes tighten, your heart has to pump much harder to push blood through them, which raises your blood pressure. It works by blocking calcium from entering the muscle cells of your blood vessels. Calcium is what causes these muscles to contract and tighten. By blocking this process, Azelnidipine allows the blood vessels to relax and widen. As the blood vessels open up, blood flows through them much more smoothly, and your blood pressure naturally goes down.
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Alcohol

Caution

It is advised to limit alcohol intake since alcohol consumption with Uniaz 16 Tablet may increase the risk of low blood pressure and cause adverse effects, such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Caution

There is no substantial research yet on using Uniaz 16 Tablet in pregnant women. Consult your doctor if you have any concerns.

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Breast Feeding

Caution

There is no substantial research yet on using Uniaz 16 Tablet in breastfeeding/nursing mothers. Consult your doctor if you have any concerns.

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Driving

Caution

It is not known whether Uniaz 16 Tablet alters the ability to drive. Do not drive or operate machinery if you experience symptoms affecting your ability to concentrate and react. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Please consult your doctor if you have any concerns regarding using Uniaz 16 Tablet in patients with liver impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding using Uniaz 16 Tablet in patients with kidney impairment. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

There is limited information available on the usage of Uniaz 16 Tablet in children. Please consult your doctor.

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Heart

Caution

Uniaz 16 Tablet should be used with caution in patients with heart problems. Inform your doctor about any heart-related conditions before taking Uniaz 16 Tablet .

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Geriatrics

Caution

Uniaz 16 Tablet should be given with caution in elderly patients due to an increased risk of side effects. Dose adjustment may be required based on their health condition.

What if I have taken an overdose of Uniaz 16 Tablet

If you take too much of this medicine, you may experience severe dizziness, confusion, or feel like you might pass out due to a sudden drop in blood pressure. If you suspect an overdose, seek emergency medical attention.

Diet & Lifestyle Advise

  • Limit salt (sodium) intake: High salt intake raises blood pressure and can reduce the effectiveness of this medicine. Focus on fresh, whole foods and limit processed snacks.
  • Avoid grapefruit and grapefruit juice: Grapefruit can interact with this medicine, raising the amount of the drug in your body and increasing your risk of side effects.
  • Stay active: Engage in moderate aerobic exercise, such as brisk walking, cycling, or swimming, for at least 30 minutes most days of the week, as approved by your doctor.
  • Manage stress: High stress levels can temporarily elevate your blood pressure. Practice relaxation techniques like deep breathing, meditation, or yoga.
  • Limit alcohol and quit smoking: Alcohol can interact with your blood pressure medicine, and smoking damages your blood vessels, worsening cardiovascular risk.
health query

Have a query?

How Soon It Starts Working

The time required for Uniaz 16 Tablet to start to work: The exact onset time of Uniaz 16 Tablet has not been clinically established.

The time for which the effects of Uniaz 16 Tablet last: The duration of Uniaz 16 Tablet ’s effect is clinically not established.

What if you forget to take Uniaz 16 Tablet

If you miss a dose, take it as soon as you remember on the same day. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store the tablets at room temperature, ideally between 68°F and 77°F (20°C to 25°C). •Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Stand up slowly: To prevent dizziness or fainting when getting up from a sitting or lying position, stand up slowly and steady yourself.
  • Monitor your heart rate: Check your resting heart rate regularly, especially if you are also taking medicines that slow your heart rate. Tell your doctor if you notice an unusually slow heartbeat or develop dizziness or fainting.
  • Inform other healthcare providers: Always tell any doctor, dentist, or pharmacist you visit that you are taking Uniaz 16 Tablet , especially before any surgical or dental procedures.
  • Be cautious when driving: This medicine can cause dizziness, especially when you first start taking it. Do not drive or operate heavy machinery until you know how it affects you.
  • Check over-the-counter medicines: Some common over-the-counter pain relievers (like ibuprofen or naproxen) can raise your blood pressure and make this medicine less effective. Ask your pharmacist before taking them.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Other blood pressure medicines: Taking this medicine with other drugs that lower blood pressure can cause an additive effect, potentially leading to excessively low blood pressure.
  • Beta-blockers: Taking Uniaz 16 Tablet together with beta-blockers may increase the risk of a slow heart rate (bradycardia). Your doctor may monitor your heart rate and adjust treatment if necessary.
  • Certain antifungal or antibiotic medicines: Drugs such as ketoconazole or clarithromycin can inhibit CYP3A4, the main enzyme responsible for breaking down Uniaz 16 Tablet . This may increase the amount of the medicine in your body and raise the risk of side effects.
  • Certain heart or seizure medicines: Medicines like rifampicin or phenytoin can speed up how your body processes this drug, making it less effective.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

Certain foods or drinks may affect the safety or tolerability of Uniaz 16 Tablet . Important interactions include:

  • Grapefruit and grapefruit juice: Avoid consuming grapefruit products while taking this medicine. Grapefruit stops your body from breaking down the drug properly, which can dangerously raise the levels of the medicine in your blood.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Uniaz 16 Tablet belongs to the class of anti-hypertensive drugs used to treat hypertension (high blood pressure).
Uniaz 16 Tablet acts by relaxing the blood vessels. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
Please do not stop using Uniaz 16 Tablet without consulting your doctor on your own. Continue using Uniaz 16 Tablet for as long as your doctor has prescribed it to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Uniaz 16 Tablet .
Uniaz 16 Tablet is safe if used in the dose and duration recommended by your doctor. Take it exactly as directed, and do not skip any dose. Follow your doctor's guidelines carefully and inform your doctor if any of the side effects disturb you.
Take the missed dose as soon as possible. However, skip the missed dose and return to your regular dosing schedule if it is time for the next dose.
Uniaz 16 Tablet may cause side effects such as headache, fast heart rate, ankle swelling, sudden reddening of your face, and palpitations (feeling of fast or abnormal heartbeat). If these side effects persist or worsen, please consult your doctor.
No, there is no proof that Uniaz 16 Tablet worsens kidney problems. It can be used in normal doses in patients with kidney problems. In fact, it lowers blood pressure and helps to avoid injury to the kidneys due to high blood pressure. However, please consult your doctor if you have any concerns regarding the use of Uniaz 16 Tablet in patients with kidney impairment.
Take Uniaz 16 Tablet anytime in the morning or evening, usually prescribed once daily. You should take it as advised by your doctor. But take it at the same time every day so that you remember to take ityou’re your body maintains consistent levels of Uniaz 16 Tablet .
You should take Uniaz 16 Tablet for as long as it is prescribed by your doctor. You may need to take it lifelong. Do not discontinue taking it, even if you feel better or your blood pressure is well controlled as it may increase your blood pressure again and your condition may worsen.
No, Uniaz 16 Tablet is not a beta blocker. It belongs to a class of drugs called calcium channel blockers.
Uniaz 16 Tablet may cause some serious side effects such as pancreatitis (severe stomach pain, nausea and vomiting), liver problems (yellowing of skin, vomiting, nausea, and loss of appetite), and recurrent chest pain which may be a sign of heart attack. However, these side effects are rare. Remember that your doctor has prescribed Uniaz 16 Tablet because the benefit to you is greater than the risk of any potential side effects. Therefore, follow your doctor's instructions while taking Uniaz 16 Tablet .
Avoid grapefruit (chakotra) or drinking grapefruit juice while taking Uniaz 16 Tablet as it may increase the risk of severe side effects. Follow low fat and a low sodium diet, and adhere to the lifestyle changes as advised by your doctor. Before starting any new medicines or supplements, consult your doctor first.
Uniaz 16 Tablet may cause ankle or foot swelling. Raise your legs while you are sitting down. If this condition persists or worsens, consult your doctor.
This medicine is generally not recommended during pregnancy as it may cause harm to the unborn baby. If you are pregnant, planning to become pregnant, or suspect you might be, talk to your doctor right away to discuss safer alternatives.
You should consult your pharmacist or doctor before taking pain relievers like ibuprofen or naproxen. These medicines can cause your body to retain water and may reduce the blood pressure-lowering effects of your medicine. Talk to your doctor for safe pain relief options.
This medicine does not typically cause overall weight gain. However, it can cause fluid retention, which might show up as mild swelling in your ankles or feet and lead to a slight increase in weight. If you notice rapid or significant weight gain, talk to your doctor.
Yes, feeling tired or dizzy can happen, especially when you first start taking this medicine or when your dose is increased. This is usually due to your body adjusting to the lower blood pressure. If these symptoms persist or make you feel unwell, talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. National Center for Biotechnology Information (NCBI). Pmc4348133 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  2. National Center for Biotechnology Information (NCBI). Azelnidipine Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Micardis 40 mg tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2022 [Accessed on 2025 Oct 3]Check here
  4. Telmisartan [Internet]. Ncbi.nlm.nih.gov. 2022 [Accessed on 05 March 2025]Check here
  5. Zhang W, Chen B, Zhang Y, Luo J. Clinical use of azelnidipine in the treatment of hypertension in Chinese patients. Therapeutics and Clinical Risk Management. 2015 Feb;309. [Accessed on 05 March 2025]Check here
  6. PubChem. Azelnidipine [Internet]. pubchem.ncbi.nlm.nih.gov. [Accessed on 05 March 2025]Check here
  7. Ram CVS. Therapeutic Usefulness of a Novel Calcium Channel Blocker Azelnidipine in the Treatment of Hypertension: A Narrative Review. Cardiology and Therapy [Internet]. 2022 Dec 1. [Accessed on 05 March 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Other Info - UNI0440
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