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UNICALCIN 100IU INJECTION 1ML is used to treat high blood calcium levels, postmenopausal osteoporosis and Paget's disease. It contains Calcitonin which works by preventing bone breakdown and lowering calcium levels. In some cases, this medicine may cause side effects such as injection site reactions, nausea with or without vomiting and flushing of the face or hands. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CALCITONIN-100IU

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About UNICALCIN 100IU INJECTION 1ML

UNICALCIN 100IU INJECTION 1ML is a prescription injection used to treat certain bone disorders, including thinning bones in women after menopause (osteoporosis) and Paget's disease of the bone. It is also used to quickly lower dangerously high levels of calcium in the blood (hypercalcemia). This medicine works by regulating how your body uses calcium and maintains bone strength.

For the best results, you must inject this medicine consistently and exactly as your doctor directs. Because it is given as an injection, food intake does not affect how the medicine is absorbed, so you may take it with or without meals. To support your treatment, your doctor may also recommend specific lifestyle and dietary changes, such as eating a calcium-rich diet or taking vitamin supplements.

While taking UNICALCIN 100IU INJECTION 1ML, you may experience some mild, temporary side effects, such as flushing of your face or nausea. However, if you experience rare but serious side effects, such as severe muscle spasms, numbness in your fingers, or signs of a severe allergic reaction, you should contact your doctor immediately.

Do not take this if you are allergic to this medication or any of its ingredients. Before you start using this medicine, talk to your doctor if you have a history of kidney disease or low calcium levels in your blood, as this medicine may not be safe for you.

This medicine can interact with certain other treatments, such as lithium, which may require your doctor to adjust your doses. Always consult your doctor or pharmacist before starting this medicine if you are pregnant, planning to become pregnant, breastfeeding, or if you are caring for an elderly patient.

Uses of UNICALCIN 100IU INJECTION 1ML

Here are the main conditions where UNICALCIN 100IU INJECTION 1ML is used to regulate calcium levels and support bone health:

  • Postmenopausal osteoporosis: UNICALCIN 100IU INJECTION 1ML helps treat weak, thinning bones in women who have been through menopause for at least five years, helping to maintain bone mass.
  • Paget's disease of bone: It helps manage this chronic condition by slowing down abnormal bone breakdown, which can relieve severe bone pain and prevent skeletal deformities.
  • Hypercalcemia: It acts quickly to lower life-threateningly high levels of calcium in the blood, which are often caused by cancer or parathyroid gland disorders.

Key Benefits

UNICALCIN 100IU INJECTION 1ML offers several important benefits that help reduce bone-related complications and restore healthy calcium balance:

  • Bone Pain Relief: It helps reduce severe bone pain associated with Paget's disease, making movement and daily activities more comfortable.
  • Bone Strength Support: By preserving bone density, UNICALCIN 100IU INJECTION 1ML helps lower the risk of fractures and supports long-term bone health.
  • Rapid Calcium Reduction: It quickly lowers dangerously high blood calcium levels, helping prevent serious complications that require urgent treatment.
  • Protection Against High Calcium Complications: By reducing excess calcium in the bloodstream, it helps protect the kidneys, reduces dehydration, and improves symptoms such as confusion, weakness, and extreme fatigue.
Side effects of Unicalcin 100iu Injection 1ml
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Directions for Use

  • Follow your doctor’s recommendations on the dosage and timing of this medication to achieve optimal results.
  • UNICALCIN 100IU INJECTION 1ML will be administered by a healthcare professional.
  • Do not self-administer.

How UNICALCIN 100IU INJECTION 1ML Works

UNICALCIN 100IU INJECTION 1ML contains calcitonin, a hormone-like medicine that helps regulate calcium levels in the body and maintain healthy bones. UNICALCIN 100IU INJECTION 1ML works by slowing down the activity of osteoclasts, the specialised cells responsible for breaking down bone tissue. By reducing bone breakdown, it helps keep calcium stored in the bones, maintains bone strength, and prevents excessive calcium from being released into the bloodstream. UNICALCIN 100IU INJECTION 1ML also acts on the kidneys, helping them remove more calcium from the blood through urine. This further lowers high calcium levels and supports the body's natural calcium balance. Together, these actions help strengthen bones, reduce excessive bone loss, and lower abnormally high calcium levels in the blood.
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Alcohol

Caution

Consuming alcohol while on treatment with UNICALCIN 100IU INJECTION 1ML is not recommended since it may result in unpleasant side effects or make you more susceptible to the effects of alcohol.

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Pregnancy

Caution

UNICALCIN 100IU INJECTION 1ML should be used in pregnancy only when the benefit to the mother outweighs the risk to the foetus. Hence, inform your doctor if you are pregnant or expecting pregnancy.

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Breast Feeding

Caution

Tell your doctor if you are a nursing mother before taking UNICALCIN 100IU INJECTION 1ML; your doctor will decide whether UNICALCIN 100IU INJECTION 1ML can be taken by breastfeeding mothers.

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Driving

Safe

UNICALCIN 100IU INJECTION 1ML does not impact your ability to drive or operate machinery.

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Liver

Caution

Inform your doctor before receiving the UNICALCIN 100IU INJECTION 1ML if you have a liver impairment. It should be used with caution in patients with liver conditions as it may alter liver functioning.

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Kidney

Caution

Inform your doctor before receiving the UNICALCIN 100IU INJECTION 1ML if you have kidney impairment. Periodic examinations of urine sediment should be considered as this medicine may cause urine sediment abnormalities.

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Children

Caution

UNICALCIN 100IU INJECTION 1ML is not recommended for children as safety and effectiveness have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using UNICALCIN 100IU INJECTION 1ML. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of UNICALCIN 100IU INJECTION 1ML in elderly patients. Please consult your doctor.

What if I have taken an overdose of UNICALCIN 100IU INJECTION 1ML

If you suspect an overdose or experience severe symptoms like extreme muscle cramping, numbness, or breathing difficulties, seek immediate medical attention or call your local poison control centre right away.

Diet & Lifestyle Advise

  • Calcium and Vitamin D Intake: Ensure you are getting enough calcium and vitamin D through your diet, as advised by your doctor, to help keep your bones strong during treatment.
  • Regular Exercise: Engage in regular, low-impact weight-bearing exercises, such as walking, to help maintain bone density and support overall joint health.
  • Avoid Smoking and Excess Alcohol: Avoid smoking and limit your alcohol consumption, as both can weaken your bones and reduce the overall effectiveness of your treatment.
  • Stay Well Hydrated: Drink plenty of fluids, especially water, if you are being treated for high calcium levels, to help your kidneys filter your blood effectively.
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How Soon It Starts Working

The time required for UNICALCIN 100IU INJECTION 1ML to start to work: The time required for UNICALCIN 100IU INJECTION 1ML to show its action is unknown. The time for which the effects of UNICALCIN 100IU INJECTION 1ML last: The duration of action for UNICALCIN 100IU INJECTION 1ML is unknown.

What if you forget to take UNICALCIN 100IU INJECTION 1ML

If you miss a dose, inject it as soon as you remember. If it is almost time for your next scheduled injection, skip the missed dose and resume your regular schedule. Do not inject a double dose to make up for a missed one. Talk to your doctor or pharmacist if you are unsure of what to do.

Storage

•Store unopened vials or pre-filled syringes of UNICALCIN 100IU INJECTION 1ML in the refrigerator between 2°C and 8°C (36°F to 46°F). •Always check your specific product insert for exact room temperature storage limits.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the Solution: Always look closely at the solution before injecting; if you see any floating particles, cloudiness, or discolouration, do not use it.
  • Use Needles Only Once: Never reuse needles or syringes, as this greatly increases your risk of developing a serious infection at the injection site.
  • Rotate Injection Sites: Make sure to rotate your injection sites daily - such as alternating between your left thigh, right thigh, and abdomen - to keep your skin healthy.
  • Managing Flushing: If you frequently experience flushing after your injection, try taking your dose at bedtime to help sleep through this symptom.
  • Allergy Precaution: Your doctor may perform a skin test before your very first dose to ensure you do not have an allergic reaction to this medicine.

Drug-Drug Interactions

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Here are the medicines that may interact with UNICALCIN 100IU INJECTION 1ML and affect its safety or effectiveness:

  • Lithium: Taking UNICALCIN 100IU INJECTION 1ML may cause your kidneys to clear lithium out of your body faster, which can lower the amount of lithium in your blood and make it less effective.
  • Other bone medicines (such as bisphosphonates): Using these medicines together can cause your blood calcium levels to drop too low.

Drug-Drug Interactions

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How does the drug interact with Unicalcin 100iu Injection 1ml:
Etelcalcetide may decrease the calcium levels in the blood. Concomitant use with calcitonin may increase the risk of hypocalcemia, or low blood calcium.

How to manage the interaction:
Although there is an interaction, calcitonin can be taken with etelcalcetide if prescribed by the doctor. Consult the prescriber if you notice symptoms of hypocalcemia like numbness or tingling around your mouth, muscle spasms, or mental changes (irritability, depression, psychosis). Do not discontinue using any medication without contacting a doctor.

Drug-Food Interactions

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No clinically significant food interactions are known with UNICALCIN 100IU INJECTION 1ML when used as directed. 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[HYPOCALCEMIC AGENTS]

FAQs

UNICALCIN 100IU INJECTION 1ML is used to treat high blood calcium levels (hypercalcemia) and postmenopausal osteoporosis. Besides this, it also helps treat complications of Paget's disease.
UNICALCIN 100IU INJECTION 1ML contains Calcitonin. It reduces the activity of osteoclasts, which are the cells responsible for bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. As a result, calcitonin's suppression of osteoclasts limits the quantity of calcium released into the blood. Furthermore, it can reduce calcium resorption in the kidneys, resulting in decreased blood calcium levels.
If you have osteoporosis, avoid smoking, or try to quit. Smoking can reduce bone mineral density and increases the risk of fractures.
UNICALCIN 100IU INJECTION 1ML contains Calcitonin, a hormone that regulates the calcium level in the blood. This hormone helps in bone formation and also helps the body to reverse bone loss. Due to this, the number of cells that damages bones becomes comparatively less. Hence, the bone damage is halted. Using UNICALCIN 100IU INJECTION 1ML can increase bone formation by activation of the bone-forming cells.
Persons whose age is more than 45 years have low estrogen levels, females reaching menopause, too much consumption of alcohol, tobacco or caffeine, use of glucocorticoids and lack of calcium and vitamin D in foods are some of the factors that can increase the risk of osteoporosis.
Yes, UNICALCIN 100IU INJECTION 1ML is used together with calcium and vitamin D to treat bone loss in women with postmenopausal osteoporosis who have been postmenopausal for at least five years. UNICALCIN 100IU INJECTION 1ML inhibits the function of osteoclasts (bone breakdown), reducing bone resorption; thus, combining calcium and calcitonin could result in a positive bone balance.
This medicine is generally not recommended for use during pregnancy or while breastfeeding. Talk to your doctor or pharmacist to discuss safer alternative treatments for your bones.
Mild flushing of the face and hands is a very common side effect of this medicine. It is usually harmless and should go away on its own within a few hours. Talk to your doctor or pharmacist if the flushing becomes severe or is highly uncomfortable.
Signs of a severe allergic reaction include a sudden skin rash, hives, swelling of the face, tongue, or throat, severe dizziness, and difficulty breathing. If you experience any of these symptoms, seek emergency medical care immediately.
Unopened vials must be kept in the refrigerator. Once opened, some brands can be kept at room temperature for up to 30 days, while others must be put back in the refrigerator. Talk to your doctor or pharmacist to confirm the exact storage rules for your specific brand.
Some medical studies have shown a slight increase in the risk of certain cancers with very long-term use of this medicine. Your doctor will regularly review your treatment to ensure you are taking it for the shortest necessary duration. Talk to your doctor or pharmacist if you have concerns.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044
Other Info - UNI0021
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