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More about the Product

Composition :

UPADACITINIB-15MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Upadazen 15 mg Tablet 10's

Upadazen 15 mg Tablet 10's is used to treat ulcerative colitis (an inflammatory disease of the large intestine) and Crohn's disease (a chronic inflammatory disorder that affects the digestive tract). It is also used to treat rheumatoid arthritis (an autoimmune disease that causes joint pain and damage), psoriatic arthritis (an inflammatory condition of the joints), ankylosing spondylitis, and atopic dermatitis (eczema).

Upadazen 15 mg Tablet 10's contains Upadacitinib, which works by blocking the Janus kinase enzyme, thereby lowering inflammation and symptoms associated with inflammatory conditions.

In some cases, you may experience common side effects such as diarrhoea, headache, upper respiratory tract infection, cold, joint pains, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Avoid taking Upadazen 15 mg Tablet 10's if you are allergic to it. Inform your doctor if you have an active infection or are taking immunosuppressants, medicines that affect the immune system, or corticosteroids. Avoid taking Upadazen 15 mg Tablet 10's if you are pregnant or breastfeeding. 

Uses of Upadazen 15 mg Tablet 10's

Upadazen 15 mg Tablet 10's is used to treat ulcerative colitis, Crohn's disease, arthritis, atopic dermatitis (eczema), and a few other inflammatory conditions. The detailed uses of Upadazen 15 mg Tablet 10's are as follows:

  • Treatment of Ulcerative Colitis: Upadazen 15 mg Tablet 10's helps induce and maintain remission in moderate-to-severe ulcerative colitis.
  • Crohn’s Disease: Upadazen 15 mg Tablet 10's is used to treat Crohn’s disease with moderately to severely active disease.
  • Treatment of Rheumatoid Arthritis: Upadazen 15 mg Tablet 10's helps to manage moderate to severe rheumatoid arthritis by reducing joint pain and inflammation and slowing disease progression.
  • Management of Psoriatic Arthritis: Upadazen 15 mg Tablet 10's treats active psoriatic arthritis by reducing joint pain, swelling, and stiffness and improving overall joint function.
  • Ankylosing Spondylitis: Upadazen 15 mg Tablet 10's manages active ankylosing spondylitis by decreasing spinal inflammation, pain, and stiffness.

Key Benefits

  • Helps reduce joint pain, swelling, and stiffness in arthritis conditions.
  • Improves movement and physical activity.
  • Reduces inflammation caused by an overactive immune system.
  • Helps control skin itching, redness, and rashes in severe eczema.
  • May help when other treatments are not giving enough relief.
  • Can improve quality of life and daily functioning over time.
  • Taken as an oral tablet, making it convenient for long-term treatment.

Directions for Use

  • Upadazen 15 mg Tablet 10's can be taken with or without food.
  • It is recommended to take the medicine as directed by your doctor, depending on your medical condition.
  • Swallow Upadazen 15 mg Tablet 10's as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Upadazen 15 mg Tablet 10's Works

Upadazen 15 mg Tablet 10's contains Upadacitinib, which works by blocking the action of certain proteins in the body called Janus kinases (JAKs), which play a key role in causing inflammation. By reducing the activity of these proteins, Upadacitinib helps lower inflammation, pain, swelling, and other symptoms associated with autoimmune and inflammatory conditions.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Upadazen 15 mg Tablet 10's, so please consult a doctor.

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Pregnancy

Unsafe

Upadazen 15 mg Tablet 10's must not be taken during pregnancy. If you are a woman of child-bearing potential, use effective contraception during the treatment with Upadazen 15 mg Tablet 10's.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking Upadazen 15 mg Tablet 10's. Please consult a doctor if you have any concerns.

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Driving

Safe if prescribed

Upadazen 15 mg Tablet 10's generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this. Upadazen 15 mg Tablet 10's is not recommended for patients with severe liver problems.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Upadazen 15 mg Tablet 10's is not safe for use in children below 12 years of age. Caution should be exercised for children above 12 years. However, your paediatrician will prescribe the medicine only if needed.

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Heart

Caution

Careful consideration and monitoring of the patient is required due to increased risks of heart-related problems, particularly in patients with existing cardiovascular risk factors.

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Geriatrics

Caution

No serious adverse effects were observed; however, it requires careful consideration and caution due to the increased risk of certain adverse events, particularly infections.

What if I have taken an overdose of Upadazen 15 mg Tablet 10's

Take Upadazen 15 mg Tablet 10's only as prescribed by the physician. Do not exceed the recommended dose, as it might cause unwanted side effects. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

Diet

  • Eat a balanced diet with fruits, vegetables, whole grains, and protein to support immunity and recovery
  • Drink enough water and avoid excessive junk food or oily foods
  • Avoid raw or unhygienic food to reduce the chance of infections while your immunity is lowered

Lifestyle changes

  • Maintain good hygiene and wash hands regularly to reduce infection risk
  • Exercise regularly with gentle activities like walking or stretching to keep joints flexible
  • Get enough sleep and manage stress to support the immune system
  • Avoid close contact with people who have active infections whenever possible

Habits

  • Avoid smoking, tobacco, and excessive alcohol use
  • Wash hands regularly and maintain cleanliness to lower infection risk
  • Inform your doctor quickly if you develop fever, cough, skin rash, or signs of infection

Have a query?

How Soon It Starts Working

The time required for Upadazen 15 mg Tablet 10's to start to work: The time required for Upadazen 15 mg Tablet 10's to show its action is unknown.

The time for which the effects of Upadazen 15 mg Tablet 10's last: The duration of action for Upadazen 15 mg Tablet 10's is clinically unknown.

What if you forget to take Upadazen 15 mg Tablet 10's

If you miss a dose of Upadazen 15 mg Tablet 10's, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Upadazen 15 mg Tablet 10's if you are allergic to any of its components
  • Also, avoid Upadazen 15 mg Tablet 10's if you have a severe infection, a bloodstream infection, or if you have severe liver problems.
  • Inform your doctor if you have an infection, symptoms of infection, or a condition that increases chances of infection, are taking any medicines that affect the immune system; have or had a history of tuberculosis, chronic lung disease, liver problems, hepatitis B/C, cancer, inflammation/ulcers of the large intestine, or kidney problems; are planning to get vaccinated; or have heart problems, high cholesterol, high blood pressure, heart attack, diabetes, or blood clotting problems.
  • Inform your doctor if you notice painful blisters on the skin or if you experience breathing difficulties.
  • Let your doctor know if you have any cancer or immune system problems, cardiovascular problems like heart attack, stroke, or any previous smoking history.
  • Inform your doctor about your complete medical and medication history before starting treatment with Upadazen 15 mg Tablet 10's, which helps the physician decide the best treatment plan.

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Drug-Drug Interactions: Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Antibiotics (rifampicin)
    • Potential effect: May change the levels of Upadazen 15 mg Tablet 10's in the body
  • Antifungals (fluconazole, ketoconazole)
    • Potential effect: May alter the levels of Upadazen 15 mg Tablet 10's in the body
  • Immunosuppressants (azathioprine, mercaptopurine, cyclosporine)
    • Potential effect: May increase the risk of serious adverse effects.
  • Corticosteroids (prednisone)
    • Potential effect: May reduce the effectiveness of Upadazen 15 mg Tablet 10's.
  • Blood thinners (warfarin)
    • Potential effect: May cause bleeding problems; hence, careful consideration is needed.

Drug-Food Interactions: Avoid intake of grapefruit, as it can cause serious side effects.

Drug-Disease Interactions: Inform your doctor if you have a history of the following conditions before taking Upadazen 15 mg Tablet 10's, as it may worsen your condition or cause complications.

  • Have serious infections
  • Bloodstream infection
  • Severe liver problems
  • Tuberculosis
  • Blood clot problems
  • High cholesterol
  • Intestinal perforation, or gastrointestinal obstruction.
  • Stroke
  • Heart attack

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Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Upadazen 15 mg Tablet 10's is used to treat ulcerative colitis, Crohn's disease, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, atopic dermatitis (eczema), and a few other inflammatory conditions.

Upadazen 15 mg Tablet 10's contains Upadacitinib, which works by reducing overactive immune system activity in the body.

Diarrhoea might be a side-effect of Upadazen 15 mg Tablet 10's. Eat non-spicy meals and drink plenty of fluids to prevent dehydration if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Upadazen 15 mg Tablet 10's is not recommended for patients with severe liver impairment. Dose adjustment may be needed in patients with mild to moderate liver impairment. Please consult the doctor if you have liver problems.

Prior to starting treatment with Upadazen 15 mg Tablet 10's, your doctor may suggest a few blood tests, such as an active or latent tuberculosis test, CBC (complete blood count), LFT (liver function test), and lipid profile tests, should be done.

Caution should be exercised if you have liver problems, tuberculosis, gastrointestinal perforations, vaccinations, cancer, or serious infections. Inform your physician of your medical history before starting treatment.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

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We provide you with authentic, trustworthy and relevant information.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - UPA0040
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