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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Urmed SR 450 Tablet is used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and children above 6 years with biliary and liver diseases caused by cystic fibrosis. It contains Ursodeoxycholic acid, which helps decrease the production of cholesterol in the blood, thereby dissolving gall bladder stones composed mainly of cholesterol. It has a protective effect on the liver cells. Thus, it protects from injury caused by toxic bile acids and improves liver function. In some cases, you may experience certain common side effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, rash, dizziness, indigestion and weakness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Medsea Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

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About Urmed SR 450 Tablet

Urmed SR 450 Tablet belongs to a group of medicines called biliary agents or gallstone dissolution agents. These agents are used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in the bile, and children above 6 years old with biliary and liver diseases caused by cystic fibrosis. 

Urmed SR 450 Tablet contains ursodeoxycholic acid, which is a naturally occurring bile acid. Urmed SR 450 Tablet helps decrease the production of cholesterol in the blood, thereby dissolving gallbladder stones composed mainly of cholesterol. Urmed SR 450 Tablet has a protective effect on the liver cells from injury caused by toxic bile acids and improves liver function.

Take Urmed SR 450 Tablet with food. You are advised to take Urmed SR 450 Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, rash, dizziness, indigestion and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking Urmed SR 450 Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Do not take Urmed SR 450 Tablet if you are pregnant or breastfeeding unless prescribed. Urmed SR 450 Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with Urmed SR 450 Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Urmed SR 450 Tablet

Urmed SR 450 Tablet is used in the treatment of Gall stones, primary biliary cholangitis and biliary and liver diseases caused by cystic fibrosis. The detailed uses of Urmed SR 450 Tablet are as follows:
• Treatment for Cholestasis: Urmed SR 450 Tablet is frequently recommended to treat pregnancy-related cholestasis, a disorder marked by decreased bile flow that usually results in elevated blood bile acids.
• Promote Liver Function: Urmed SR 450 Tablet may be used to enhance bile production and promote liver function, which will help with fat digestion.
• Gallstone Management: By dissolving certain type of gallstones, especially those composed of cholesterol, Urmed SR 450 Tablet can help remove them and prevent gallbladder problems.
• Liver Diseases: To improve liver function, Urmed SR 450 Tablet is occasionally included in treatment plans for a number of liver disorders, including fatty liver disease.
• Bile Acid Malabsorption: By assisting in the regulation of bile levels in the digestive tract, it may be helpful for individuals who are suffering from bile acid malabsorption, which causes gastrointestinal symptoms.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule. Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use. Dispersible tablet: Disperse the tablet in water and consume it.

Medicinal Benefits

Urmed SR 450 Tablet contains ursodeoxycholic acid, which is a naturally occurring bile acid. It belongs to a group of medicines called the biliary agent or gallstone dissolution agents used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile children above 6 years with biliary and liver diseases caused by cystic fibrosis. Urmed SR 450 Tablet breaks down the cholesterol that has formed into gall bladder stones, thereby dissolving the stones. Urmed SR 450 Tablet has a protective effect on the liver cells and the immune system, thereby improving liver function. Urmed SR 450 Tablet decreases the amount of cholesterol produced by the liver and absorbed by the intestine. In patients with primary biliary cirrhosis, Urmed SR 450 Tablet increases the bile flow.

How Urmed SR 450 Tablet Works

Urmed SR 450 Tablet contains ursodeoxycholic acid, which is a naturally occurring bile acid. Urmed SR 450 Tablet helps decrease the production of cholesterol in the blood, thereby dissolving gallbladder stones composed mainly of cholesterol. Urmed SR 450 Tablet has a protective effect on the liver cells from injury caused by toxic bile acids and improves liver function.

Storage

Store in a cool and dry place away from sunlight
Side effects of Urmed SR 450 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

What if I have taken an overdose of Urmed SR 450 Tablet

Do not take more than the prescribed dose of Urmed SR 450 Tablet as it may cause overdose. The symptoms of overdose include diarrhoea. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Urmed SR 450 Tablet if you are allergic to any of its contents, if you have inflammation of gall bladder and bile ducts, narrowing or blockage of bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer. Inform your doctor before taking Urmed SR 450 Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Consult your doctor before taking Urmed SR 450 Tablet with other medicines as Urmed SR 450 Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine), increase the effect of immunosuppressants (cyclosporine), oral contraceptives (oestrogen) and cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Do not take Urmed SR 450 Tablet if you are pregnant or breastfeeding unless prescribed. Urmed SR 450 Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with Urmed SR 450 Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Include foods such as bell peppers, citrus fruits, leafy vegetables, tomatoes, milk, fish, low-fat dairy, beans, nuts, lentils, tofu and tempeh in your diet.
  • Eat a healthy, well-balanced diet, which includes fruits and vegetables.
  • Foods rich in vitamins B and C and calcium are good for the gallbladder.
  • Plant-based protein foods such as beans, nuts, lentils, tofu and tempeh help prevent gallbladder disease.
  • Avoid high-fat, trans-fat and processed foods.
  • White bread, white pasta and sugars should be avoided.
  • Avoid tobacco and alcohol consumption.

Habit Forming

No

Therapeutic Class

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Urmed SR 450 Tablet as it may cause increased dizziness and liver damage.

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Pregnancy

Caution

Urmed SR 450 Tablet belongs to pregnancy category B. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Urmed SR 450 Tablet ; your doctor will decide whether breastfeeding mothers can take Urmed SR 450 Tablet or not.

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Driving

Caution

Urmed SR 450 Tablet does not affect your ability to drive. However, you are advised to be cautious while driving if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Urmed SR 450 Tablet can be given to children with caution above 6 years and only if prescribed by the doctor.

Have a query?

FAQs

Urmed SR 450 Tablet is used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and children above 6 years with biliary and liver diseases caused by cystic fibrosis.

Urmed SR 450 Tablet works in decreasing the production of cholesterol and by dissolving the cholesterol in bile, thereby preventing the formation of gallstones. Urmed SR 450 Tablet decreases the toxic levels of bile acids that accumulate in primary biliary cirrhosis.

Do not discontinue Urmed SR 450 Tablet without consulting your doctor. To treat your condition effectually, continue taking Urmed SR 450 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you have any difficulty taking Urmed SR 450 Tablet .

Diarrhoea might be a side-effect of Urmed SR 450 Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Avoid taking aluminium-containing antacids along with Urmed SR 450 Tablet , as they might interfere with its absorption. Maintain a gap of 2 hours between both.

Urmed SR 450 Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine). Urmed SR 450 Tablet might increase the effect of immunosuppressants (cyclosporine). Cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Inform your doctor before taking Urmed SR 450 Tablet with other medicines to avoid unpleasant side effects.

Oral contraceptives (oestrogen) might promote the formation of gallstones. Consult your doctor if you have any concerns regarding this, your doctor may advise other contraception methods.

There is no evidence that Urmed SR 450 Tablet affects fertility. Please consult the doctor if you have any concerns regarding this.

Urmed SR 450 Tablet should be given to paediatric patients only if prescribed by the doctor. It may be used in children above 6 years with liver and biliary diseases caused by cystic fibrosis.

The doctor will determine when to take Urmed SR 450 Tablet based on your condition. Urmed SR 450 Tablet should be taken after a meal with a glass of milk or a small snack. Take the prescribed number of tablets distributed throughout the day as advised by the physician.

Yes, Urmed SR 450 Tablet is safe to use if prescribed by the doctor. Like all medicines, Urmed SR 450 Tablet may also cause side effects in some people. However, if any of the side effects are bothersome, please consult the doctor.

Urmed SR 450 Tablet has a protective effect on the liver cells from injury caused by toxic bile acids and improves liver function.

Urmed SR 450 Tablet may cause weight gain in some people. Consult the doctor if you notice rapid weight gain, especially in your face and midsection.

Avoid taking other medicines concomitantly with Urmed SR 450 Tablet as it might reduce or intensify the effect of other medicines. Colestyramine and colestipol should be taken 2 hours before or after Urmed SR 450 Tablet . Consult your doctor before taking Urmed SR 450 Tablet with other medicines as Urmed SR 450 Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine), increase the effect of immunosuppressants (cyclosporine), oral contraceptives (oestrogen) and cholesterol-lowering agents (clofibrate) might promote the formation of gallstones.

Country of origin

INDIA

Manufacturer/Marketer address

259,1st floor, Hauz Rani, opp. max hospital Saket,New Delhi, India
Other Info - URM0001

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