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  3. Sedogest-450 mg Tablet 10's

Sedogest-450 mg Tablet 10's, Pack of 10 TABLETS
Sedogest-450 mg Tablet 10's, Pack of 10 TABLETS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Sedogest-450 mg Tablet is used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and children above 6 years with biliary and liver diseases caused by cystic fibrosis. It contains Ursodeoxycholic acid, which helps decrease the production of cholesterol in the blood, thereby dissolving gall bladder stones composed mainly of cholesterol. It has a protective effect on the liver cells. Thus, it protects from injury caused by toxic bile acids and improves liver function. In some cases, you may experience certain common side effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, rash, dizziness, indigestion and weakness. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

URSODEOXYCHOLIC ACID-450MG

Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Sedogest-450 mg Tablet

Sedogest-450 mg Tablet belongs to a group of medicines called biliary agents or gallstone dissolution agents. These agents are used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in the bile, and children above 6 years old with biliary and liver diseases caused by cystic fibrosis. 

Sedogest-450 mg Tablet contains ursodeoxycholic acid, which is a naturally occurring bile acid. Sedogest-450 mg Tablet helps decrease the production of cholesterol in the blood, thereby dissolving gallbladder stones composed mainly of cholesterol. Sedogest-450 mg Tablet has a protective effect on the liver cells from injury caused by toxic bile acids and improves liver function.

Take Sedogest-450 mg Tablet with food. You are advised to take Sedogest-450 mg Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, rash, dizziness, indigestion and weakness. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking Sedogest-450 mg Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Do not take Sedogest-450 mg Tablet if you are pregnant or breastfeeding unless prescribed. Sedogest-450 mg Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with Sedogest-450 mg Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Sedogest-450 mg Tablet

Sedogest-450 mg Tablet is used in the treatment of Gall stones, primary biliary cholangitis and biliary and liver diseases caused by cystic fibrosis. The detailed uses of Sedogest-450 mg Tablet are as follows:
• Treatment for Cholestasis: Sedogest-450 mg Tablet is frequently recommended to treat pregnancy-related cholestasis, a disorder marked by decreased bile flow that usually results in elevated blood bile acids.
• Promote Liver Function: Sedogest-450 mg Tablet may be used to enhance bile production and promote liver function, which will help with fat digestion.
• Gallstone Management: By dissolving certain type of gallstones, especially those composed of cholesterol, Sedogest-450 mg Tablet can help remove them and prevent gallbladder problems.
• Liver Diseases: To improve liver function, Sedogest-450 mg Tablet is occasionally included in treatment plans for a number of liver disorders, including fatty liver disease.
• Bile Acid Malabsorption: By assisting in the regulation of bile levels in the digestive tract, it may be helpful for individuals who are suffering from bile acid malabsorption, which causes gastrointestinal symptoms.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule. Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use. Dispersible tablet: Disperse the tablet in water and consume it.

Medicinal Benefits

Sedogest-450 mg Tablet contains ursodeoxycholic acid, which is a naturally occurring bile acid. It belongs to a group of medicines called the biliary agent or gallstone dissolution agents used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile children above 6 years with biliary and liver diseases caused by cystic fibrosis. Sedogest-450 mg Tablet breaks down the cholesterol that has formed into gall bladder stones, thereby dissolving the stones. Sedogest-450 mg Tablet has a protective effect on the liver cells and the immune system, thereby improving liver function. Sedogest-450 mg Tablet decreases the amount of cholesterol produced by the liver and absorbed by the intestine. In patients with primary biliary cirrhosis, Sedogest-450 mg Tablet increases the bile flow.

How Sedogest-450 mg Tablet Works

Sedogest-450 mg Tablet contains ursodeoxycholic acid, which is a naturally occurring bile acid. Sedogest-450 mg Tablet helps decrease the production of cholesterol in the blood, thereby dissolving gallbladder stones composed mainly of cholesterol. Sedogest-450 mg Tablet has a protective effect on the liver cells from injury caused by toxic bile acids and improves liver function.

Storage

Store in a cool and dry place away from sunlight
Side effects of Sedogest-450 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Focus on eating nutrient-rich foods such as citrus fruits, spinach, ginger, garlic, turmeric, and fermented foods to improve immunity and general health.
  • Drink plenty of water to stay hydrated, and think about taking probiotics, zinc, vitamin C, and vitamin D supplements.
  • Adopt healthful practices such as leading a balanced lifestyle and remaining at home when necessary.

What if I have taken an overdose of Sedogest-450 mg Tablet

Do not take more than the prescribed dose of Sedogest-450 mg Tablet as it may cause overdose. The symptoms of overdose include diarrhoea. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Sedogest-450 mg Tablet if you are allergic to any of its contents, if you have inflammation of gall bladder and bile ducts, narrowing or blockage of bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer. Inform your doctor before taking Sedogest-450 mg Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Consult your doctor before taking Sedogest-450 mg Tablet with other medicines as Sedogest-450 mg Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine), increase the effect of immunosuppressants (cyclosporine), oral contraceptives (oestrogen) and cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Do not take Sedogest-450 mg Tablet if you are pregnant or breastfeeding unless prescribed. Sedogest-450 mg Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with Sedogest-450 mg Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include foods such as bell peppers, citrus fruits, leafy vegetables, tomatoes, milk, fish, low-fat dairy, beans, nuts, lentils, tofu and tempeh in your diet.
  • Eat a healthy, well-balanced diet, which includes fruits and vegetables.
  • Foods rich in vitamins B and C and calcium are good for the gallbladder.
  • Plant-based protein foods such as beans, nuts, lentils, tofu and tempeh help prevent gallbladder disease.
  • Avoid high-fat, trans-fat and processed foods.
  • White bread, white pasta and sugars should be avoided.
  • Avoid tobacco and alcohol consumption.

Habit Forming

No

Therapeutic Class

BILE ACID SEQUESTRANTS

Sedogest-450 mg Tablet Substitute

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Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Sedogest-450 mg Tablet as it may cause increased dizziness and liver damage.

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Pregnancy

Caution

Sedogest-450 mg Tablet belongs to pregnancy category B. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Sedogest-450 mg Tablet ; your doctor will decide whether breastfeeding mothers can take Sedogest-450 mg Tablet or not.

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Driving

Caution

Sedogest-450 mg Tablet does not affect your ability to drive. However, you are advised to be cautious while driving if you experience dizziness.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Sedogest-450 mg Tablet can be given to children with caution above 6 years and only if prescribed by the doctor.

Have a query?

FAQs

Sedogest-450 mg Tablet is used to treat gallstones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and children above 6 years with biliary and liver diseases caused by cystic fibrosis.

Sedogest-450 mg Tablet works in decreasing the production of cholesterol and by dissolving the cholesterol in bile, thereby preventing the formation of gallstones. Sedogest-450 mg Tablet decreases the toxic levels of bile acids that accumulate in primary biliary cirrhosis.

Do not discontinue Sedogest-450 mg Tablet without consulting your doctor. To treat your condition effectually, continue taking Sedogest-450 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you have any difficulty taking Sedogest-450 mg Tablet .

Diarrhoea might be a side-effect of Sedogest-450 mg Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Avoid taking aluminium-containing antacids along with Sedogest-450 mg Tablet , as they might interfere with its absorption. Maintain a gap of 2 hours between both.

Sedogest-450 mg Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine). Sedogest-450 mg Tablet might increase the effect of immunosuppressants (cyclosporine). Cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Inform your doctor before taking Sedogest-450 mg Tablet with other medicines to avoid unpleasant side effects.

Oral contraceptives (oestrogen) might promote the formation of gallstones. Consult your doctor if you have any concerns regarding this, your doctor may advise other contraception methods.

There is no evidence that Sedogest-450 mg Tablet affects fertility. Please consult the doctor if you have any concerns regarding this.

Sedogest-450 mg Tablet should be given to paediatric patients only if prescribed by the doctor. It may be used in children above 6 years with liver and biliary diseases caused by cystic fibrosis.

The doctor will determine when to take Sedogest-450 mg Tablet based on your condition. Sedogest-450 mg Tablet should be taken after a meal with a glass of milk or a small snack. Take the prescribed number of tablets distributed throughout the day as advised by the physician.

Yes, Sedogest-450 mg Tablet is safe to use if prescribed by the doctor. Like all medicines, Sedogest-450 mg Tablet may also cause side effects in some people. However, if any of the side effects are bothersome, please consult the doctor.

Sedogest-450 mg Tablet has a protective effect on the liver cells from injury caused by toxic bile acids and improves liver function.

Sedogest-450 mg Tablet may cause weight gain in some people. Consult the doctor if you notice rapid weight gain, especially in your face and midsection.

Avoid taking other medicines concomitantly with Sedogest-450 mg Tablet as it might reduce or intensify the effect of other medicines. Colestyramine and colestipol should be taken 2 hours before or after Sedogest-450 mg Tablet . Consult your doctor before taking Sedogest-450 mg Tablet with other medicines as Sedogest-450 mg Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine), increase the effect of immunosuppressants (cyclosporine), oral contraceptives (oestrogen) and cholesterol-lowering agents (clofibrate) might promote the formation of gallstones.

Country of origin

India

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - SED0050

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Apr 18, 2025 | 8:37 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.10065.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020675s017lbl.pdf
  3. https://medlineplus.gov/druginfo/meds/a699047.html
  4. https://www.drugs.com/mtm/ursodiol.html
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