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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
V-Parin 5000I.U Inj is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. It contains Heparin, which works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation. Some people may experience haemorrhage (bleeding), thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Whats That

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Composition :

HEPARIN-5000IU

Manufacturer/Marketer :

Vh Bhagat & Company

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About V-Parin 5000I.U Inj

V-Parin 5000I.U Inj belongs to a class of drugs called anticoagulants or blood thinners. V-Parin 5000I.U Inj is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks. Deep vein thrombosis is a medical condition in which blood clots form in deep veins, usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called mini-strokes. These have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. V-Parin 5000I.U Inj works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

V-Parin 5000I.U Inj will be administered by a healthcare professional; do not self-administer. Some people may experience haemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of V-Parin 5000I.U Inj do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to V-Parin 5000I.U Inj or any other medicines, please tell your doctor. It is not known whether V-Parin 5000I.U Inj harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using V-Parin 5000I.U Inj. V-Parin 5000I.U Inj is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking V-Parin 5000I.U Inj.

Uses of V-Parin 5000I.U Inj

Prevention of blood clots.

Directions for Use

V-Parin 5000I.U Inj will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

V-Parin 5000I.U Inj is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). V-Parin 5000I.U Inj also reduces the risk of blood clots during surgeries (like heart surgery). V-Parin 5000I.U Inj is used as an anticoagulant in blood transfusion and in a dialysis procedure.

How V-Parin 5000I.U Inj Works

V-Parin 5000I.U Inj works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot), preventing blood clot formation.

Storage

Store in a cool and dry place away from sunlight

What if I have taken an overdose of V-Parin 5000I.U Inj

The overdose of V-Parin 5000I.U Inj is unlikely as it is administered by a doctor. Too much heparin may cause bleeding. Therefore, if you suspect any adverse reactions or unusual symptoms or more severe bleeding while on treatment with V-Parin 5000I.U Inj, please inform your doctor immediately.

Drug Warnings

Use V-Parin 5000I.U Inj cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving V-Parin 5000I.U Inj. Patients should inform the doctor that they are receiving V-Parin 5000I.U Inj before any surgery is scheduled.

Drug-Drug Interactions

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HeparinOritavancin
Critical

Drug-Drug Interactions

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HeparinOritavancin
Critical
How does the drug interact with V-Parin 5000I.U Inj:
Using V-Parin 5000I.U Inj with Oritavancin can make V-Parin 5000I.U Inj less effective as a therapy.

How to manage the interaction:
V-Parin 5000I.U Inj is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess V-Parin 5000I.U Inj's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with V-Parin 5000I.U Inj:
Taking Ticlopidine with V-Parin 5000I.U Inj can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with V-Parin 5000I.U Inj is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with V-Parin 5000I.U Inj:
When V-Parin 5000I.U Inj is taken with bazedoxifene the effects of V-Parin 5000I.U Inj are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with V-Parin 5000I.U Inj is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with V-Parin 5000I.U Inj:
Taking Alteplase with V-Parin 5000I.U Inj can increase the risk of bleeding.

How to manage the interaction:
Taking V-Parin 5000I.U Inj with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with V-Parin 5000I.U Inj:
Taking Mifepristone with V-Parin 5000I.U Inj can increase the risk of negative side effects.

How to manage the interaction:
Taking V-Parin 5000I.U Inj with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with V-Parin 5000I.U Inj:
Taking Tenecteplase with V-Parin 5000I.U Inj can increase the risk of bleeding.

How to manage the interaction:
Taking V-Parin 5000I.U Inj with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with V-Parin 5000I.U Inj:
Sulfadiazine enhances the effects of V-Parin 5000I.U Inj by slowing its breakdown.

How to manage the interaction:
Co-administration of Sulfadiazine with V-Parin 5000I.U Inj can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with V-Parin 5000I.U Inj:
Co-administration of Cefpodoxime with V-Parin 5000I.U Inj may enhance the levels or effects of V-Parin 5000I.U Inj by anticoagulation (preventing blood from clotting).

How to manage the interaction:
Although there is an interaction, Cefpodoxime can be taken with V-Parin 5000I.U Inj if prescribed by the doctor. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
How does the drug interact with V-Parin 5000I.U Inj:
Co-administration of Cangrelor with V-Parin 5000I.U Inj can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although there is a possible interaction between V-Parin 5000I.U Inj and Cangrelor, you can take these medicines together if prescribed by a doctor. However, if you have any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, you should seek immediate medical attention. Do not stop using any medications without a doctor's advice.
HeparinAntithrombin iii
Severe
How does the drug interact with V-Parin 5000I.U Inj:
Using V-Parin 5000I.U Inj together with antithrombin III may increase the risk of bleeding.

How to manage the interaction:
Although taking Antithrombin iii and V-Parin 5000I.U Inj together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these signs - bleeding, bruising, vomiting, headache, dizziness, weakness, or blood in your urine or stools, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate

Drug-Food Interactions

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HEPARIN-5000IUHerbal products/medicines
Moderate
Common Foods to Avoid:
Garlic Pill

How to manage the interaction:
Taking V-Parin 5000I.U Inj along with herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba can lead to an increased risk of bleeding Avoid taking herbs and supplements such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba while taking V-Parin 5000I.U Inj.

Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS
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Alcohol

Caution

You are recommended to avoid consumption of alcohol with V-Parin 5000I.U Inj as it may cause severe bleeding in the stomach and harmful side effects to the liver.

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Pregnancy

Caution

V-Parin 5000I.U Inj is a Category C pregnancy drug and should be given to pregnant women only if clearly needed and has more benefits than risks. Preservative-free forms are preferred in pregnant women as preservatives such as benzyl alcohol may cross the placenta.

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Breast Feeding

Caution

V-Parin 5000I.U Inj should be given to breastfeeding mothers only if clearly needed and has more benefits than risks.

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Driving

Safe if prescribed

V-Parin 5000I.U Inj usually does not affect your ability to drive or operate machinery.

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Liver

Caution

V-Parin 5000I.U Inj should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

V-Parin 5000I.U Inj should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

V-Parin 5000I.U Inj is not recommended for children below 2 months.

Have a query?

FAQs

V-Parin 5000I.U Inj is used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.

V-Parin 5000I.U Inj works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Thereby, preventing blood clot formation.

No, you are not recommended to take ibuprofen with V-Parin 5000I.U Inj as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with V-Parin 5000I.U Inj.

Yes, V-Parin 5000I.U Inj may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, V-Parin 5000I.U Inj may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, V-Parin 5000I.U Inj may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking V-Parin 5000I.U Inj to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Country of origin

India

Manufacturer/Marketer address

40 - B/2, Shankar Smruti Sir Bhalchandra Road, Dadar (E), Mumbai-400014
Other Info - VPA0002

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