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compositionComposition:DIVALPROEX SODIUM-500MG
prescriptionPrescription Medicine
Valance 500 Oral Solution 100 ml

Valance 500 Oral Solution is used to treat epilepsy (seizures/fits). It can be used alone or in combination with other medications to treat complex partial seizures that occur alone or alongside other types of seizures. It contains Divalproex sodium, which decreases the brain's excessive and abnormal nerve activity, thereby helping to control seizures. In some cases, it may cause common side effects such as drowsiness, dizziness, and nausea. Before taking this medicine, you should inform your doctor if you are allergic to any of its components, if you are pregnant/breastfeeding, and about all the medications you are taking, as well as any pre-existing medical conditions.

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Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

DIVALPROEX SODIUM-500MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Valance 500 Oral Solution

Valance 500 Oral Solution is used to treat epilepsy (seizures/fits). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

Valance 500 Oral Solution contains 'Divalproex sodium', which raises a brain chemical called GABA. This calms the brain, lowers abnormal activity, and helps stop seizures.

In some cases, you may experience certain common side effects, such as drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor if you are allergic to any of its contents, have liver problems, or urea cycle disorders. Avoid taking Valance 500 Oral Solution if you are pregnant, as it may cause severe birth defects. Consult your doctor before using Valance 500 Oral Solution if you are breastfeeding. Valance 500 Oral Solution should be given to children only if prescribed by your doctor.

Uses of Valance 500 Oral Solution

Valance 500 Oral Solution is used in the treatment of epilepsy (seizures). The detailed uses of Valance 500 Oral Solution are as follows:

  • Partial seizures: It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.
  • Simple and complex absence seizures: It may also be used alone or with other medications to treat both simple and complex absence seizures (which cause a brief loss and return of consciousness for a few seconds).

Key Benefits

  • Valance 500 Oral Solution belongs to a group of medicines called anticonvulsants or antiepileptics, primarily used to treat epilepsy (seizures or fits).
  • It increases the levels of a natural chemical (GABA) in the brain, which helps reduce excessive and abnormal nerve activity in the brain, thereby helping to control seizures.
  • Valance 500 Oral Solution is used alone or in combination with other medications to treat complex partial seizures, whether they occur alone or alongside other types of seizures.
Side effects of Valance 500 Oral Solution 100 ml
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Eat a balanced diet containing enough proteins, fibre, healthy fats, vegetables and fruits.
  • Get quality sleep for about 7-9 hours.
  • Try to manage stress with meditation or yoga.
  • Drink enough water.
  • Exercise regularly as it helps regulate appetite.

Directions for Use

  • Valance 500 Oral Solution can be taken with or without food, or as advised by the doctor.
  • Shake the bottle well before each use.
  • Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided with the pack.
  • Replace the bottle cap tightly after each use.
  • Avoid using regular household spoons, as they may not accurately measure the dose.
  • Your doctor may adjust the dose and frequency of this medication based on your medical condition.

How Valance 500 Oral Solution Works

Valance 500 Oral Solution contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Valance 500 Oral Solution helps control seizures.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Valance 500 Oral Solution , as it may cause increased drowsiness and dizziness.

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Pregnancy

Unsafe

Valance 500 Oral Solution belongs to pregnancy category D. Avoid taking Valance 500 Oral Solution if you are pregnant, as it could lead to serious birth defects. Consult your doctor for further advice.

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Breast Feeding

Caution

Valance 500 Oral Solution may pass into breastmilk. Consult your doctor before taking Valance 500 Oral Solution if you are breastfeeding.

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Driving

Unsafe

Valance 500 Oral Solution causes drowsiness and dizziness. Therefore, do not drive or operate machinery until you are mentally alert.

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Liver

Unsafe

Valance 500 Oral Solution should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this. Dose adjustment may be needed in patients with kidney impairment.

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Children

Caution

Valance 500 Oral Solution should be given to children only if prescribed by a doctor.

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Heart

Caution

Please inform your doctor if you have heart problems before taking Valance 500 Oral Solution , as there is limited information available on its safety in such cases.

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Geriatrics

Caution

Valance 500 Oral Solution can be taken if you're geriatric, but it requires careful monitoring and medical supervision.

What if I have taken an overdose of Valance 500 Oral Solution

Do not take more than the prescribed dose of Valance 500 Oral Solution , as it may lead to serious side effects. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for energy generation of energy.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try to reduce or avoid them.
  • Please pay attention to your overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Have a query?

How Soon It Starts Working

  • The time required for Valance 500 Oral Solution to start to work: Valance 500 Oral Solution ideally shows its action within 15 minutes to 2 hours after administration.
  • The time for which the effects of Valance 500 Oral Solution last: The effect of Valance 500 Oral Solution lasts for 4 to 6 hours.

What if you forget to take Valance 500 Oral Solution

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one and continue your regular dosage routine. Avoid taking two doses at once.

Storage

• Store in a cool and dry place away from sunlight.• Keep Valance 500 Oral Solution out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Valance 500 Oral Solution if you are allergic to any of its contents, have significant liver disease or dysfunction, or have urea cycle disorders.
  • Inform your doctor before taking Valance 500 Oral Solution if you have pancreatitis, blood problems, or multi-organ hypersensitivity.
  • Consult your doctor immediately if you experience suicidal tendencies while taking Valance 500 Oral Solution .
  • Valance 500 Oral Solution may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature), and liver problems.
  • Please do not stop taking Valance 500 Oral Solution without consulting your doctor to avoid worsening of seizures.
  • Do not take Valance 500 Oral Solution if you are pregnant, as it could cause serious birth defects. If you are of childbearing age, use effective contraception while taking Valance 500 Oral Solution .
  • Consult your doctor before taking Valance 500 Oral Solution if you are breastfeeding.
  • Valance 500 Oral Solution should be given to children only if prescribed by your doctor.
  • Avoid driving or operating machinery, as Valance 500 Oral Solution may cause drowsiness and dizziness.
  • Avoid consuming alcohol along with Valance 500 Oral Solution , as it could lead to increased drowsiness and dizziness.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Valance 500 Oral Solution may have interaction with pain killers (aspirin), anti-epileptics (pregabalin, topiramate, phenobarbital, primidone, phenytoin, carbamazepine, lamotrigine, felbamate, ethosuximide), anti-HIV (zidovudine), anti-depressant (duloxetine, escitalopram, amitriptyline, nortriptyline), anti-psychotic (aripiprazole, lurasidone, quetiapine), anti-anxiety (alprazolam), anti-TB (rifampicin), anti-coagulant (warfarin), antibiotics (imipenem, meropenem), and benzodiazepine (diazepam).

Drug-Food Interactions: Avoid alcohol consumption while taking Valance 500 Oral Solution , as it might cause increased dizziness and sleepiness. Alcohol intake might also provoke seizures.

Drug-Disease Interactions: Valance 500 Oral Solution may interact with disease conditions such as depression, liver disease, urea cycle disorders, suicidal tendency, HIV disease, and thrombocytopenia (low levels of platelets).

DivalproexGlycerol phenylbutyrate
Critical
DivalproexDoripenem
Severe

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Valance 500 Oral Solution 100 ml:
Coadministration of Glycerol phenylbutyrate and Valance 500 Oral Solution 100 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Valance 500 Oral Solution 100 ml together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexDoripenem
Severe
How does the drug interact with Valance 500 Oral Solution 100 ml:
Co-administration of Valance 500 Oral Solution 100 ml and Doripenem can reduce the blood levels of Valance 500 Oral Solution 100 ml sodium and increase the risk of developing seizures.

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 100 ml with Doripenem can possibly result in an interaction, it can be taken when your doctor has advised it. Do not stop using any medications without first talking to your doctor.
DivalproexMipomersen
Severe
How does the drug interact with Valance 500 Oral Solution 100 ml:
Co-administration of Valance 500 Oral Solution 100 ml and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 100 ml and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.
DivalproexMeropenem
Severe
How does the drug interact with Valance 500 Oral Solution 100 ml:
Co-administration of Valance 500 Oral Solution 100 ml and Meropenem can reduce the blood levels of Valance 500 Oral Solution 100 ml sodium.

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 100 ml with Meropenem can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.
DivalproexErtapenem
Severe
How does the drug interact with Valance 500 Oral Solution 100 ml:
Coadministration of Ertapenem with Valance 500 Oral Solution 100 ml may reduce the blood levels of Valance 500 Oral Solution 100 ml and increase the risk of developing seizures.

How to manage the interaction:
Although there is a possible interaction, ertapenem can be taken with Valance 500 Oral Solution 100 ml if prescribed by the doctor. Consult the doctor if you experience loss of seizure control or changes in behaviour. Do not stop using any medications without talking to your doctor.
DivalproexKetamine
Severe
How does the drug interact with Valance 500 Oral Solution 100 ml:
Co-administration of Valance 500 Oral Solution 100 ml and Ketamine can increase the risk of side effects.

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 100 ml and Ketamine can lead to an interaction, it can be taken if advised by your doctor. If you have any symptoms such as dizziness, drowsiness, shortness of breath, or impairment in thinking and motor coordination, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
DivalproexLeflunomide
Severe
How does the drug interact with Valance 500 Oral Solution 100 ml:
Co-administration of Valance 500 Oral Solution 100 ml and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Valance 500 Oral Solution 100 ml and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
DivalproexSodium phenylbutyrate
Severe
How does the drug interact with Valance 500 Oral Solution 100 ml:
Co-administration of Sodium phenylbutyrate and Valance 500 Oral Solution 100 ml can increase ammonia levels in the blood and is generally not recommended for patients with urea cycle disorders.

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 100 ml with Sodium phenylbutyrate can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
DivalproexTeriflunomide
Severe
How does the drug interact with Valance 500 Oral Solution 100 ml:
Co-administration of Valance 500 Oral Solution 100 ml and teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Valance 500 Oral Solution 100 ml and teriflunomide can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexBuprenorphine
Severe
How does the drug interact with Valance 500 Oral Solution 100 ml:
Co-administration of buprenorphine with Valance 500 Oral Solution 100 ml may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Buprenorphine with Valance 500 Oral Solution 100 ml can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Valance 500 Oral Solution belongs to a group of medicines called anticonvulsants or antiepileptics, used to treat epilepsy (seizures/fits). It is used alone or in combination with other medications to treat complex partial seizures (which affect only one side of the brain and cause impaired consciousness), whether they occur alone or alongside other types of seizures.

Valance 500 Oral Solution contains 'Divalproex sodium,' which works by increasing the levels of a natural chemical in the brain called gamma-aminobutyric acid (GABA). This helps reduce excessive and abnormal nerve activity in the brain, producing a calming effect. Therefore, Valance 500 Oral Solution helps control seizures.

Do not discontinue Valance 500 Oral Solution without consulting your doctor. To treat your condition effectively, continue taking Valance 500 Oral Solution for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Valance 500 Oral Solution , your doctor will reduce the dose gradually to avoid worsening of seizures.

Valance 500 Oral Solution may cause weight gain due to increased appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Valance 500 Oral Solution . Avoid getting pregnant while taking Valance 500 Oral Solution as it could lead to severe birth defects. Do not stop taking Valance 500 Oral Solution and consult your doctor immediately if you become pregnant.

Valance 500 Oral Solution may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Valance 500 Oral Solution .

Topiramate (an anticonvulsant) should not be taken along with Valance 500 Oral Solution as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature), and liver problems.

It is crucial to consult with your doctor before discontinuing Valance 500 Oral Solution . Abruptly stopping this medication can lead to severe consequences, mainly if it's prescribed to treat conditions like epilepsy.

Valance 500 Oral Solution can indeed make you sleepy. This is a common side effect of the medication. If you're experiencing excessive drowsiness, please consult your doctor.

Yes, Valance 500 Oral Solution can cause hair loss as a side effect. While this isn't a common side effect, it can occur in some people. If you notice significant hair loss while taking Valance 500 Oral Solution , it's essential to consult with your doctor.

Yes, Valance 500 Oral Solution can potentially damage your liver. While this is a rare side effect, being aware of the risk is essential. Signs of liver damage may include yellowing of the skin or eyes or jaundice, dark urine, abdominal pain, light-coloured stools, nausea and vomiting. If you experience any of these symptoms while taking Valance 500 Oral Solution , seeking medical attention is crucial.

Avoid consumption of alcohol while taking Valance 500 Oral Solution , as it may cause increased drowsiness and dizziness.

If you experience abdominal pain, nausea, and anorexia while taking Valance 500 Oral Solution , it's essential to contact your doctor immediately. These symptoms can be signs of a severe side effect, such as liver damage.

An overdose of Valance 500 Oral Solution can be a severe medical emergency. The symptoms of an overdose may include heart block, excess sleepiness, and deep coma. If you or someone you know has taken an overdose of Valance 500 Oral Solution , please seek immediate medical attention.

The common side effects of Valance 500 Oral Solution include drowsiness, dizziness, nausea, back pain, increased appetite, constipation, diarrhoea, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

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Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - VAL0272
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