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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Valgress-CR-500 Tablet is used to treat epilepsy/seizures/fits and bipolar disorder. It contains 'Sodium valproate', which decreases the brain's excessive and abnormal nerve activity. Thus, it helps in controlling seizures. On the other hand, it increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thus, it helps treat bipolar disorder.

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Synonym :

VALPROIC ACID

Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Valgress-CR-500 Tablet

Valgress-CR-500 Tablet is used to treat epilepsy/seizures/fits and bipolar disorder. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. 

Valgress-CR-500 Tablet contains 'Sodium valproate', which decreases the brain's excessive and abnormal nerve activity. Thus, it helps in controlling seizures. Valgress-CR-500 Tablet increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thus, it helps treat bipolar disorder. 

Use Valgress-CR-500 Tablet as prescribed by your doctor. Sometimes, it may cause certain side effects such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually. However, if the side effects persist or worsen, inform your doctor immediately.

Before using Valgress-CR-500 Tablet , inform your doctor about your children's medical conditions, sensitivities, and all medications used. To treat your condition effectually, continue using Valgress-CR-500 Tablet for as long as your doctor has prescribed. Valgress-CR-500 Tablet should be gradually withdrawn, so please do not stop using Valgress-CR-500 Tablet without consulting your doctor. Consult your doctor immediately if you observe any suicidal tendencies in your children.

Uses of Valgress-CR-500 Tablet

Treatment of Epilepsy and Bipolar disorder

Directions for Use

Give this medicine to your child as directed by your physician or per instructions in the package leaflet.

Medicinal Benefits

Sodium valproate reduces the brain's excessive and unusual nerve activity. On the other hand, it helps to raise the quantity of a chemical substance called GABA in the brain, which helps to stop nerve transmission and has a calming effect. Thus, it aids in the treatment of epilepsy, seizures, and fits, as well as bipolar disorder.

How Valgress-CR-500 Tablet Works

Valgress-CR-500 Tablet contains 'Sodium valproate', which decreases the brain's excessive and abnormal nerve activity. Thus, it helps in controlling seizures. Valgress-CR-500 Tablet increases the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect. Thus, it helps treat bipolar disorder.

Storage

Store in a cool and dry place away from sunlight
Side effects of Valgress-CR-500 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Include fruits, vegetables, and leafy greens rich in vitamins C and K.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Avoid tobacco products as smoking can worsen gum disease.
  • Stay hydrated by drinking water to flush bacteria and food particles.
  • Consider vitamin supplements if deficient to support gum health.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Swish with coconut oil for its antibacterial properties to reduce plaque.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Consult your dentist if gums bleed consistently.
  • Apply a cold compress to the affected area for 10 to 15 minutes multiple times a day.
  • Elevate your head while resting or sleeping to reduce fluid accumulation.
  • Drink lots of water to eliminate excess fluids.
  • Limit salty foods as they can cause water retention.
  • To stimulate lymphatic drainage, gently massage the swollen area.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • To keep your vocal cords lubricated and hydrated, drink lots of water.
  • Suck on ice chips, popsicles, or lozenges to clear your throat and reduce hoarseness.
  • Your voice cords may be soothed and healed by honey's antibacterial and anti-inflammatory properties.
  • Gargle with salt water.
  • Using a steam humidifier or inhaling steam might help minimize hoarseness and release mucus.

What if I have taken an overdose of Valgress-CR-500 Tablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Valgress-CR-500 Tablet may include breathing problems, feeling confused or changes to your normal behaviour, feeling or being sick (nausea or vomiting), headaches or feeling dizzy, muscle weakness, and passing out. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

The presence of other medical problems or using other medications may affect the use of this medicine. So, before using Valgress-CR-500 Tablet , let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use this medication on your own unless prescribed by the doctor. Do not exceed the stated recommended dose.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateMeropenem
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valgress-CR-500 Tablet:
Combining Sodium phenylbutyrate and Valgress-CR-500 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valgress-CR-500 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Valgress-CR-500 Tablet:
Co-administration of Meropenam and Valgress-CR-500 Tablet together can reduce the effect of Valgress-CR-500 Tablet.

How to manage the interaction:
Co-administration of Meropenam and Valgress-CR-500 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Valgress-CR-500 Tablet:
Co-administration of Valgress-CR-500 Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valgress-CR-500 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Valgress-CR-500 Tablet:
Co-administration of Lithium with Valgress-CR-500 Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valgress-CR-500 Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Valgress-CR-500 Tablet:
Using buprenorphine together with Valgress-CR-500 Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valgress-CR-500 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Valgress-CR-500 Tablet:
Co-administration of Teriflunomide and Valgress-CR-500 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valgress-CR-500 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Valgress-CR-500 Tablet:
Co-administration of Vorinostat with Valgress-CR-500 Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valgress-CR-500 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Valgress-CR-500 Tablet:
The combined use of Ertapenem and Valgress-CR-500 Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valgress-CR-500 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Valgress-CR-500 Tablet:
Co-administration of Ketamine and Valgress-CR-500 Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valgress-CR-500 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Valgress-CR-500 Tablet:
Co-administration of Leflunomide and Valgress-CR-500 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valgress-CR-500 Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps utilise fat instead of glucose for energy generation.
  • Have a seizure response plan, and help those around you know what to do.
  • Prepare your children's living area; small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures are and try reducing or avoiding them.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Let your child rest well and sleep well.

Habit Forming

Not enough scientific literature available around this hence it is best to consult your physician

Therapeutic Class

ANTICONVULSANT

Valgress-CR-500 Tablet Substitute

Substitutes safety advice
  • Encorate 500 Tablet 10's

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    8.16per tablet
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  • VALPO CR 500MG TABLET

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  • Valparin 500 Alkalets Tablet 10's

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    12.24per tablet
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Alcohol

Not applicable

It is intended for Children.

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Pregnancy

Not applicable

It is intended for Children.

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Breast Feeding

Not applicable

It is intended for Children.

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Driving

Not applicable

It is intended for Children.

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Liver

Caution

Inform your doctor if your child has liver problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform your doctor if your child has kidney problems. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Valgress-CR-500 Tablet can be given safely to children. Give this medicine to your child in the doses as prescribed by the doctor.

Have a query?

FAQs

Valgress-CR-500 Tablet is used to treat epilepsy/seizures/fits and bipolar disorder.

Valgress-CR-500 Tablet decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizure episodes.

Valgress-CR-500 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps block nerve transmission across the brain and provides a calming effect.

Do not discontinue Valgress-CR-500 Tablet without consulting your doctor. To treat your child's condition effectually, continue using Valgress-CR-500 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if your child experiences difficulty while taking Valgress-CR-500 Tablet ; your doctor will gradually reduce the dose to avoid worsening seizures.

Valgress-CR-500 Tablet may change the results of liver enzymes and urine and blood tests. Inform the person doing the tests that your child using Valgress-CR-500 Tablet .

Country of origin

INDIA

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - VAL0236

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