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  3. Valparin 500 Alkalets Tablet 10's

Prescription drug
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Valparin 500 Alkalets Tablet 10's, Pack of 10 TABLETS
Valparin 500 Alkalets Tablet 10's, Pack of 10 TABLETS
Valparin 500 Alkalets Tablet 10's, Pack of 10 TABLETS
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Composition :

SODIUM VALPROATE-500MG

Manufacturer/Marketer :

Sanofi India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Valparin 500 Alkalets Tablet

Valparin 500 Alkalets Tablet is used to treat epilepsy/seizures/fits. Additionally, Valparin 500 Alkalets Tablet is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. 
­ 
Valparin 500 Alkalets Tablet contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Valparin 500 Alkalets Tablet increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 
 
You can take Valparin 500 Alkalets Tablet with or without food. You are advised to take Valparin 500 Alkalets Tablet as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Please do not stop taking Valparin 500 Alkalets Tablet without consulting your doctor to avoid worsening of seizures. Contact your doctor if your child gets her first period whilst on treatment with Valparin 500 Alkalets Tablet . Do not take Valparin 500 Alkalets Tablet if you are pregnant, as it could cause serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Valparin 500 Alkalets Tablet . Consult your doctor before taking Valparin 500 Alkalets Tablet if you are breastfeeding. Do not drive or operate machinery as Valparin 500 Alkalets Tablet may cause drowsiness and dizziness. Avoid consuming alcohol along with Valparin 500 Alkalets Tablet as it could lead to increased dizziness and sleepiness.

Uses of Valparin 500 Alkalets Tablet

Valparin 500 Alkalets Tablet is used in the treatment of epilepsy, bipolar disorder, and migraine. The detailed uses of Valparin 500 Alkalets Tablet are as follows:<br/>• Seizure Management: Valparin 500 Alkalets Tablet is primarily used to manage various types of seizures in individuals with epilepsy, helping to stabilise electrical activity in the brain.<br/>• Bipolar Disorder Treatment: Valparin 500 Alkalets Tablet can be utilized in the treatment of bipolar disorder, aiding in mood stabilization and reducing the frequency of mood swings.<br/>• Migraine Prevention: Valparin 500 Alkalets Tablet may also be prescribed to prevent migraines, providing relief from recurrent headaches.<br/>

Have a query?

Directions for Use

  • Valparin 500 Alkalets Tablet can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Valparin 500 Alkalets Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Valparin 500 Alkalets Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Additionally, Valparin 500 Alkalets Tablet is also used to treat bipolar disorder and prevent migraine headaches. Valparin 500 Alkalets Tablet decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Valparin 500 Alkalets Tablet is used to treat both localized (seizures which affect only a part of the brain) and generalized seizures (seizures which affect the entire brain).

How Valparin 500 Alkalets Tablet Works

Valparin 500 Alkalets Tablet contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Valparin 500 Alkalets Tablet increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder.

Storage

Keep Valparin 500 Alkalets Tablet out of reach and sight of children.
Side effects of Valparin 500 Alkalets Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Avoid tobacco products, as smoking can worsen gum problems.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Consult your dentist if gums bleed consistently.
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

What if I have taken an overdose of Valparin 500 Alkalets Tablet

Do not take more than the prescribed dose of Valparin 500 Alkalets Tablet as it may cause an overdose. The symptoms of overdose include headache, dizziness, confusion, memory loss, tiredness, feeling sick or being sick, blurred vision due to pupil of the eye becoming smaller, poor reflexes, weak or floppy muscles, fits, loss of consciousness, behavioural changes and breathing difficulties such as fast breathing, shortness of breath or chest pain. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Valparin 500 Alkalets Tablet if you are allergic to any of its contents; if you have liver problems, porphyria, urine-related problems (like urea cycle disorder), diabetes, an immune system disorder or kidney problems. Consult your doctor immediately if you experience suicidal tendencies while taking Valparin 500 Alkalets Tablet . Contact your doctor if your child gets her first period during the treatment with Valparin 500 Alkalets Tablet . Do not take Valparin 500 Alkalets Tablet if you are pregnant unless prescribed by the doctor, as it is a pregnancy category C medicine and can cause serious congenital disabilities. Consult your doctor before taking Valparin 500 Alkalets Tablet if you are breastfeeding. Valparin 500 Alkalets Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Valparin 500 Alkalets Tablet as it could lead to increased dizziness and sleepiness. 

Drug-Drug Interactions

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateTeriflunomide
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valparin 500 Alkalets Tablet:
Combining Sodium phenylbutyrate and Valparin 500 Alkalets Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valparin 500 Alkalets Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Valparin 500 Alkalets Tablet:
Co-administration of Teriflunomide and Valparin 500 Alkalets Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valparin 500 Alkalets Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Valparin 500 Alkalets Tablet:
The combined use of Ertapenem and Valparin 500 Alkalets Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valparin 500 Alkalets Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Valparin 500 Alkalets Tablet:
Co-administration of Lithium with Valparin 500 Alkalets Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valparin 500 Alkalets Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Valparin 500 Alkalets Tablet:
Co-administration of Meropenam and Valparin 500 Alkalets Tablet together can reduce the effect of Valparin 500 Alkalets Tablet.

How to manage the interaction:
Co-administration of Meropenam and Valparin 500 Alkalets Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Valparin 500 Alkalets Tablet:
Co-administration of Leflunomide and Valparin 500 Alkalets Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valparin 500 Alkalets Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Valparin 500 Alkalets Tablet:
Co-administration of Vorinostat with Valparin 500 Alkalets Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valparin 500 Alkalets Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Valparin 500 Alkalets Tablet:
Using buprenorphine together with Valparin 500 Alkalets Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valparin 500 Alkalets Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Valparin 500 Alkalets Tablet:
Co-administration of Valparin 500 Alkalets Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valparin 500 Alkalets Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Valparin 500 Alkalets Tablet:
Co-administration of Ketamine and Valparin 500 Alkalets Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valparin 500 Alkalets Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps maintain weight and improve overall health. 
  • Rest well; get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Have a seizure response plan that helps those around you know what to do.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Valparin 500 Alkalets Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Valparin 500 Alkalets Tablet as it may cause increased dizziness and sleepiness.

bannner image

Pregnancy

Unsafe

Valparin 500 Alkalets Tablet belongs to pregnancy category D. Avoid taking Valparin 500 Alkalets Tablet if you are pregnant as it could lead to serious birth defects.

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Breast Feeding

Consult your doctor

Valparin 500 Alkalets Tablet may pass into breastmilk. Consult your doctor before taking Valparin 500 Alkalets Tablet if you are breastfeeding.

bannner image

Driving

Unsafe

Valparin 500 Alkalets Tablet causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Unsafe

Valparin 500 Alkalets Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

bannner image

Children

Safe if prescribed

Valparin 500 Alkalets Tablet can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

FAQs

Valparin 500 Alkalets Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache).

Valparin 500 Alkalets Tablet decreases the excessive and abnormal nerve activity in the brain. It balances the brain&amp;#039;s chemical messenger and prevents overactivity of the brain, thereby controlling seizures episodes.

Valparin 500 Alkalets Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.

Valparin 500 Alkalets Tablet limits the transmission of nerve pain, thereby prevents migraine headache. Migraine is a neurological condition which is characterized by intense headaches.

Do not discontinue Valparin 500 Alkalets Tablet without consulting your doctor. To treat your condition effectually, continue taking Valparin 500 Alkalets Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Valparin 500 Alkalets Tablet ; your doctor will reduce the dose gradually to avoid worsening of seizures.

Birth-control pills like oestrogen-containing products may affect the way Valparin 500 Alkalets Tablet works. It is better to consult the doctor if you are using birth control pills to avoid pregnancy.

Valparin 500 Alkalets Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Valparin 500 Alkalets Tablet might cause fertility issues in both men and women. However, it can be reversible upon discontinuation of Valparin 500 Alkalets Tablet . In rare cases, Valparin 500 Alkalets Tablet can be a contributing factor in male infertility.

Limit caffeine intake, avoid smoking and mouthwashes containing alcohol, drink water regularly, and chew sugar-free gum/candy might prevent dry mouth.

Valparin 500 Alkalets Tablet may change the results of liver enzymes, and urine and blood tests. Inform the person doing the tests that you are taking Valparin 500 Alkalets Tablet .

Store Valparin 500 Alkalets Tablet at room temperature, in a dry place. Keep out of sight and reach of children.

Valparin 500 Alkalets Tablet may cause side effects like stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

No, avoid consumption of alcohol while taking Valparin 500 Alkalets Tablet as it may cause increased dizziness and sleepiness.

Yes, Valparin 500 Alkalets Tablet causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

No, taking higher than the recommended dose of Valparin 500 Alkalets Tablet will not be more effective and may cause unpleasant side effects. Do not take more than the prescribed dose of Valparin 500 Alkalets Tablet as it may cause an overdose.

Country of origin

India

Manufacturer/Marketer address

CT Survey No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072.
Other Info - VAL0034

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:42 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.1500.pdf
  2. https://www.nhs.uk/medicines/sodium-valproate/http://mri.cts-mrp.eu/download/DE_H_0642_002_FinalPI_2of4.pdf
  3. https://www.drugs.com/cons/valproate-sodium-intravenous.html
  4. https://www.medsafe.govt.nz/consumers/cmi/e/Epilim.pdf

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