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Valrest-500 mg ER Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). It helps reduce mood swings and improve impulsive behaviour.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Sbs Biotech

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Valrest-500 mg ER Tablet

Valrest-500 mg ER Tablet is an oral prescription medicine used to treat different types of seizures in epilepsy. It is also prescribed to manage manic episodes associated with bipolar disorder and to prevent migraine headaches in adults. This medicine works by calming overactive nerves in the brain to help you stay balanced and seizure-free.

For Valrest-500 mg ER Tablet to work effectively, you must take it consistently every day at the same times. It is usually taken once or twice a day, and taking it with or after food can help prevent stomach upset. Making simple lifestyle adjustments, such as getting enough sleep, managing daily stress, and eating regular meals, can also support your treatment and improve your overall results.

While taking Valrest-500 mg ER Tablet , you might experience mild side effects like drowsiness, nausea, or temporary hair thinning. However, you must contact your doctor immediately if you notice serious symptoms such as severe upper stomach pain, unexplained bruising, or yellowing of your skin and eyes.

Do not take this if you have active liver disease or a family history of severe liver problems. Before starting Valrest-500 mg ER Tablet , tell your doctor if you have kidney problems, urea cycle disorders, or mitochondrial disease. It is especially important to discuss your medical history because this medicine should not be taken during pregnancy unless there is no other treatment option.

This medicine can interact with alcohol, which can make you feel extremely sleepy and increase the risk of seizures, so it is best to avoid drinking while on this treatment. You should also consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, or if you are an older adult, as your body may handle the medication differently.
 

Uses of Valrest-500 mg ER Tablet

Valrest-500 mg ER Tablet is used to treat different types of seizures in epilepsy. The detailed uses of Valrest-500 mg ER Tablet are as follows:

  • Epilepsy (Seizures): Valrest-500 mg ER Tablet helps control and prevent various kinds of seizures, including generalised and partial seizures, by stabilising the electrical activity in the brain.
  • Bipolar Disorder (Manic Episodes): Valrest-500 mg ER Tablet manages periods of extreme excitement, high energy, or irritability by helping to restore the balance of certain natural chemicals in your brain.
  • Migraine Prevention: Valrest-500 mg ER Tablet helps by reducing how often you get severe migraine headaches, though it is not used to treat a migraine attack that has already started.
     

Key Benefits

Valrest-500 mg ER Tablet helps manage certain neurological conditions by stabilising electrical activity in the brain. Depending on the condition being treated, it helps control seizures, stabilise mood, or reduce the frequency of migraine attacks, supporting a better quality of life.

  • Helps Control Seizures: By reducing abnormal electrical activity in the brain, Valrest-500 mg ER Tablet helps decrease the frequency of seizures, allowing you to carry out daily activities with greater safety and confidence.
  • Supports Mood Stability: For individuals with bipolar disorder, Valrest-500 mg ER Tablet helps reduce extreme mood swings and prevent manic episodes, promoting greater emotional stability and improved daily functioning.
  • Helps Prevent Migraine Attacks: When used for migraine prevention, Valrest-500 mg ER Tablet helps reduce the frequency of migraine episodes, allowing you to spend more time enjoying your daily activities with fewer interruptions from headaches.
     
Side effects of Valrest-500 mg ER Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Valrest-500 mg ER Tablet can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Valrest-500 mg ER Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Valrest-500 mg ER Tablet Works

Valrest-500 mg ER Tablet contains sodium valproate, which helps to look at the chemistry of the brain. Your brain relies on electrical signals and chemical messengers to function. Sometimes, overactive electrical signals can cause a seizure or trigger a migraine. Valrest-500 mg ER Tablet works by increasing the levels of a natural calming chemical in your brain called gamma-aminobutyric acid (GABA). By boosting GABA, Valrest-500 mg ER Tablet helps block the excessive and rapid electrical signals that cause brain cells to overreact. This balancing effect calms brain activity, which helps prevent the onset of seizures, reduces the frequency of migraines, and stabilises fluctuating moods.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Valrest-500 mg ER Tablet as it may cause increased dizziness and sleepiness.

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Pregnancy

Unsafe

Valrest-500 mg ER Tablet belongs to pregnancy category D. Avoid taking Valrest-500 mg ER Tablet if you are pregnant as it could lead to serious birth defects.

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Breast Feeding

Consult your doctor

Valrest-500 mg ER Tablet may pass into breastmilk. Consult your doctor before taking Valrest-500 mg ER Tablet if you are breastfeeding.

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Driving

Unsafe

Valrest-500 mg ER Tablet causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Valrest-500 mg ER Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Valrest-500 mg ER Tablet can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

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Heart

Consult your doctor

It is unknown whether Valrest-500 mg ER Tablet is safe for use in cardiac patients or not. Please consult your physician.

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Geriatrics

Caution

Valrest-500 mg ER Tablet should be given with caution in elderly patients due to age-related side effects. Seek medical advice before using Valrest-500 mg ER Tablet .

What if I have taken an overdose of Valrest-500 mg ER Tablet

In case of an accidental overdose, seek immediate emergency medical attention right away. Symptoms of an overdose can include extreme drowsiness, confusion, shallow breathing, or loss of consciousness.

Diet & Lifestyle Advise

  • Maintain a consistent sleep routine: Lack of sleep is a well-known trigger for both seizures and migraines. Aim for 7 to 8 hours of quality sleep every night.
  • Avoid alcohol completely: Alcohol can increase the sedative effects of Valrest-500 mg ER Tablet , making you extremely dizzy or sleepy, and it can also lower your seizure threshold.
  • Eat regular meals: Skipping meals can trigger migraines or affect your metabolic balance. Eating consistent, balanced meals helps maintain steady energy levels.
  • Keep a health diary: Track your daily doses, any seizures or migraine attacks, and any mild side effects you notice. This record is highly valuable for your doctor during check-ups.
  • Stay adequately hydrated: Drinking enough water throughout the day supports overall brain health and can help reduce the frequency of headaches.
     
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How Soon It Starts Working

  • The time required for Valrest-500 mg ER Tablet to start to work: Valrest-500 mg ER Tablet ideally shows its action within 2 hours after administration.
  • The time for which the effects of Valrest-500 mg ER Tablet last: The effect of Valrest-500 mg ER Tablet lasts for 24 hours.

What if you forget to take Valrest-500 mg ER Tablet

If you miss a dose of Valrest-500 mg ER Tablet , take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, talk to your doctor or pharmacist.

Storage

• Store Valrest-500 mg ER Tablet tablets, capsules, or oral solutions at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Use highly effective birth control: This medication carries a high risk of causing severe birth defects. If you are of childbearing age, discuss safe, reliable contraception options with your doctor.
  • Do not stop treatment abruptly: Stopping Valrest-500 mg ER Tablet suddenly can cause severe, continuous seizures that can be dangerous. Always consult your doctor before making any changes.
  • Avoid driving or operating machinery: This medicine can make you feel sleepy or dizzy, especially when you first start taking it. Do not perform tasks requiring full alertness until you know how it affects you.
  • Monitor your mood: Pay close attention to any sudden changes in your mental health. Report any signs of depression, anxiety, or unusual thoughts to your doctor immediately.
  • Get regular blood tests: Your doctor will need to perform periodic blood tests to monitor your liver function, platelet counts, and the level of medicine in your body. Keep all your medical appointments.
     

Drug-Drug Interactions

verifiedApollotooltip
  • Aspirin: Taking aspirin with Valrest-500 mg ER Tablet can increase the level of this medicine in your blood, raising the risk of side effects.
  • Other seizure medications: Medicines like carbamazepine, phenytoin, or phenobarbital can speed up how your body processes Valrest-500 mg ER Tablet , while taking it with lamotrigine can increase lamotrigine levels to unsafe amounts.
  • Blood thinners: Combining this medicine with blood thinners like warfarin can increase your risk of bleeding or bruising.
     
DivalproexGlycerol phenylbutyrate
Critical

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Valrest-500 mg ER Tablet:
Coadministration of Glycerol phenylbutyrate and Valrest-500 mg ER Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Valrest-500 mg ER Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Valrest-500 mg ER Tablet:
Coadministration of Valrest-500 mg ER Tablet and Lamotrigine can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Valrest-500 mg ER Tablet and Lamotrigine, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.
How does the drug interact with Valrest-500 mg ER Tablet:
Co-administration of buprenorphine with Valrest-500 mg ER Tablet may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Buprenorphine with Valrest-500 mg ER Tablet can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexSodium phenylbutyrate
Severe
How does the drug interact with Valrest-500 mg ER Tablet:
Co-administration of Sodium phenylbutyrate and Valrest-500 mg ER Tablet can increase ammonia levels in the blood and is generally not recommended for patients with urea cycle disorders.

How to manage the interaction:
Co-administration of Valrest-500 mg ER Tablet with Sodium phenylbutyrate can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
DivalproexEsketamine
Severe
How does the drug interact with Valrest-500 mg ER Tablet:
Coadministration of Esketamine and Valrest-500 mg ER Tablet can increase the side effects of esketamine.

How to manage the interaction:
Although taking Valrest-500 mg ER Tablet and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience any symptoms like drowsiness and impaired motor coordination, consult the doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Valrest-500 mg ER Tablet:
Co-administration of Valrest-500 mg ER Tablet and teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Valrest-500 mg ER Tablet and teriflunomide can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Valrest-500 mg ER Tablet:
Co-administration of Valrest-500 mg ER Tablet and leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Valrest-500 mg ER Tablet and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valrest-500 mg ER Tablet:
Co-administration of Valrest-500 mg ER Tablet and Meropenem can reduce the blood levels of Valrest-500 mg ER Tablet sodium.

How to manage the interaction:
Co-administration of Valrest-500 mg ER Tablet with Meropenem can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without a doctor's advice.
DivalproexMipomersen
Severe
How does the drug interact with Valrest-500 mg ER Tablet:
Co-administration of Valrest-500 mg ER Tablet and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Valrest-500 mg ER Tablet and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.
How does the drug interact with Valrest-500 mg ER Tablet:
Coadministration of Ertapenem with Valrest-500 mg ER Tablet may reduce the blood levels of Valrest-500 mg ER Tablet and increase the risk of developing seizures.

How to manage the interaction:
Although there is a possible interaction, ertapenem can be taken with Valrest-500 mg ER Tablet if prescribed by the doctor. Consult the doctor if you experience loss of seizure control or changes in behaviour. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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  • Alcohol: Drinking alcohol while taking this medicine can cause severe drowsiness, impair coordination, and increase the risk of seizures.

 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Valrest-500 mg ER Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache).
Valrest-500 mg ER Tablet decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizure episodes.
Valrest-500 mg ER Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.
Valrest-500 mg ER Tablet limits the transmission of nerve pain, thereby preventing migraine headaches. Migraines are a neurological condition characterised by intense headaches.
Do not discontinue Valrest-500 mg ER Tablet without consulting your doctor. To treat your condition effectively, continue taking Valrest-500 mg ER Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Valrest-500 mg ER Tablet ; your doctor will reduce the dose gradually to avoid worsening of seizures.
Birth-control pills like oestrogen-containing products may affect the way Valrest-500 mg ER Tablet works. It is better to consult the doctor if you are using birth control pills to avoid pregnancy.
Valrest-500 mg ER Tablet might cause fertility issues in both men and women. However, it can be reversible upon discontinuation of Valrest-500 mg ER Tablet . In rare cases, Valrest-500 mg ER Tablet can be a contributing factor in male infertility.
Limit caffeine intake, avoid smoking and mouthwashes containing alcohol, drink water regularly, and chew sugar-free gum/candy might prevent dry mouth.
Valrest-500 mg ER Tablet may change the results of liver enzymes, urine and blood tests. Inform the person doing the tests that you are taking Valrest-500 mg ER Tablet .
Store Valrest-500 mg ER Tablet at room temperature, in a dry place. Keep out of sight and reach of children.
Valrest-500 mg ER Tablet may cause side effects like stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Yes, Valrest-500 mg ER Tablet causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.
No, taking higher than the recommended dose of Valrest-500 mg ER Tablet will not be more effective and may cause unpleasant side effects. Do not take more than the prescribed dose of Valrest-500 mg ER Tablet as it may cause an overdose.
No, you should avoid drinking alcohol while taking this medicine. Alcohol can increase the sleepiness and dizziness caused by Valrest-500 mg ER Tablet and may also increase your risk of having a seizure. Talk to your doctor.
You must contact your doctor immediately before planning a pregnancy or as soon as you discover you are pregnant. This medicine carries a high risk of causing physical and developmental birth defects. Your doctor will help you evaluate alternative treatments. Talk to your doctor.
Yes, weight gain is a common side effect for some people taking this medicine. Managing your diet and staying physically active can help, but you should not make drastic changes without medical advice. Talk to your doctor.
No, you should never stop taking this medicine on your own. Stopping it suddenly can cause your seizures to return more frequently or become more severe. If you need to stop, your doctor will guide you on how to reduce your dose safely. Talk to your doctor.
Your doctor needs to check your blood regularly to monitor your liver health, check your blood platelet counts, and ensure the level of medicine in your body is within a safe and effective range. Talk to your doctor.
Some people experience temporary thinning or loss of hair while taking this medicine. In most cases, the hair grows back once the treatment is stopped or adjusted, though it may grow back with a slightly different texture. Talk to your doctor.
You can take this medicine with or without food. However, taking it with or immediately after a meal can help reduce common stomach upsets, such as nausea or indigestion. Talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Nanhera, Kala Amb Industrial Area, Sirmaur, Himachal Pradesh
Other Info - VAL0255
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