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  1. Home
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  3. Vasograin Plus Tablet 10's

Prescription drug
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Vasograin Plus Tablet 10's, Pack of 10
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Vasograin Plus Tablet 10's is used to prevent migraine symptoms uch as headache, nausea, and vomiting. It contains two medicines, namely Sumatriptan and Naproxen. It may cause common side effects, such as dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeats, and heartburn.
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Composition :

NAPROXEN-500MG + SUMATRIPTAN-85MG

Manufacturer/Marketer :

Cadila Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Vasograin Plus Tablet 10's

Vasograin Plus Tablet 10's is used to prevent migraine symptoms such as headache, nausea, and vomiting. Migraine is a neurological condition which is characterised by an intense pulsating, throbbing, pounding, debilitating headache which usually occurs on one side of the head; however, it can occur on both sides or shift. Hormonal changes, stress, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches. 

Vasograin Plus Tablet 10's is a combination of two drugs: Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain, thereby causing the narrowing of the brain's blood vessels, which in turn affects the blood flow patterns associated with headache. Naproxen is a painkiller which works by blocking the effect of chemical messengers that cause pain.  Thus, Vasograin Plus Tablet 10's prevents symptoms of migraine-like headache, nausea and vomiting. 
 
You are advised to take Vasograin Plus Tablet 10's as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeats, and heartburn. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Consult your doctor if you are pregnant or breastfeeding. Vasograin Plus Tablet 10's should not be taken during the third trimester of pregnancy. Vasograin Plus Tablet 10's may cause drowsiness and dizziness, so drive with caution. Vasograin Plus Tablet 10's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Vasograin Plus Tablet 10's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects. 

Uses of Vasograin Plus Tablet 10's

Vasograin Plus Tablet 10's is used in the treatment of migraine. The detailed uses of Vasograin Plus Tablet 10's are as follows:

  • Treats Migraine Headaches: Vasograin Plus Tablet 10's effectively treats acute migraine attacks with or without aura by narrowing the swollen blood vessels around the brain and by blocking the effect of chemical messengers that cause pain.
  • Relieves Migraine-Associated Symptoms: Vasograin Plus Tablet 10's helps relieve symptoms such as nausea, vomiting, headache, and sensitivity to light and sound.

Have a query?

Directions for Use

  • Vasograin Plus Tablet 10's can be taken with or without food or as advised by a doctor.
  • It is advised to take Vasograin Plus Tablet 10's exactly as prescribed by your doctor, following the recommended dosage and duration to get optimal results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

Vasograin Plus Tablet 10's is a combination of two drugs, Sumatriptan and Naproxen. Vasograin Plus Tablet 10's is indicated for the acute treatment of migraine with or without aura. Sumatriptan is a serotonin receptor agonist that acts on the serotonin (5-HT) receptors located in the brain, which causes the narrowing of the brain's blood vessels, thereby affecting the blood flow patterns with a headache. Naproxen is a pain killer which works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the effect of COX enzymes, fewer prostaglandins are produced, thereby reducing pain in migraine.

How Vasograin Plus Tablet 10's Works

Vasograin Plus Tablet 10's is a combination of two drugs: Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain, thereby causing the narrowing of the brain's blood vessels, which in turn affects the blood flow patterns associated with headache. Naproxen is a painkiller which works by blocking the effect of chemical messengers that cause pain.  Thus, Vasograin Plus Tablet 10's prevents symptoms of migraine-like headache, nausea and vomiting.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Vasograin Plus Tablet
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of Vasograin Plus Tablet 10's

Do not take more than the prescribed dose of Vasograin Plus Tablet 10's as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Vasograin Plus Tablet 10's if you are allergic to any of its contents; if you have had any recent heart surgery or stroke, blood circulation problems, heart problems, narrowing of blood vessels to the stomach, legs, arms or kidneys, or uncontrolled high blood pressure; if you are taking MAO inhibitors, antidepressant or have taken them in the last 14 days; or if you have taken 5-HT agonists called triptan or ergotamine in the last 24 hours. Inform your doctor if you have high blood pressure, asthma, diabetes, epilepsy, overweight, heart, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Vasograin Plus Tablet 10's should not be taken during the third trimester of pregnancy. Vasograin Plus Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Vasograin Plus Tablet 10's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol with Vasograin Plus Tablet 10's as it could lead to increased drowsiness. Stop taking Vasograin Plus Tablet 10's and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. 

Drug-Drug Interactions

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NaproxenKetorolac
Critical
NaproxenCidofovir
Critical

Drug-Drug Interactions

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NaproxenKetorolac
Critical
How does the drug interact with Vasograin Plus Tablet:
Coadministration of Ketorolac with Vasograin Plus Tablet can increase the risk or severity of gastric bleeding and ulceration.

How to manage the interaction:
Taking Ketorolac with Vasograin Plus Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
NaproxenCidofovir
Critical
How does the drug interact with Vasograin Plus Tablet:
Taking cidofovir with Vasograin Plus Tablet may increase the risk or severity of kidney problems

How to manage the interaction:
Taking Vasograin Plus Tablet with Cidofovir is generally avoided as it can possibly result in an interaction. You should seek immediate medical attention if you develop signs and symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm.
NaproxenMeloxicam
Critical
How does the drug interact with Vasograin Plus Tablet:
Co-administration of Vasograin Plus Tablet with Meloxicam can increase the risk or severity of gastric bleeding, ulceration, and rarely, perforation leading to serious blood loss.

How to manage the interaction:
Taking Meloxicam with Vasograin Plus Tablet is not advised as it can possibly result in an interaction, it can be taken if your doctor has advised it. You should seek immediate medical attention if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness.
SumatriptanMethylergometrine
Critical
How does the drug interact with Vasograin Plus Tablet:
Coadministration of Vasograin Plus Tablet with Methylergometrine can reduce the blood flow and increase the risk of high blood pressure or heart-related problems.

How to manage the interaction:
Taking Vasograin Plus Tablet with Methylergometrine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
SumatriptanIsocarboxazid
Critical
How does the drug interact with Vasograin Plus Tablet:
Combining Isocarboxazid with Vasograin Plus Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related problems.

How to manage the interaction:
Taking Isocarboxazid with Vasograin Plus Tablet is not recommended, please consult your doctor before taking it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
SumatriptanDihydroergotamine
Critical
How does the drug interact with Vasograin Plus Tablet:
Coadministration of Dihydroergotamine with Vasograin Plus Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related side effects.

How to manage the interaction:
Taking Dihydroergotamine with Vasograin Plus Tablet is not recommended, please consult your doctor before taking it. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
SumatriptanBromocriptine
Critical
How does the drug interact with Vasograin Plus Tablet:
Coadministration of Bromocriptine with Vasograin Plus Tablet can increase the risk or severity of side effects like high blood pressure or heart-related disorders.

How to manage the interaction:
Although there is an interaction between Bromocriptine and Vasograin Plus Tablet, they can be taken together if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, consult a doctor. Do not discontinue any medication without consulting a doctor.
SumatriptanErgotamine
Critical
How does the drug interact with Vasograin Plus Tablet:
Coadministration of Ergotamine with Vasograin Plus Tablet can reduce blood flow and increase the risk of serious side effects such as high blood pressure or heart-related disorders.

How to manage the interaction:
There may be a possibility of interaction between Vasograin Plus Tablet and Ergotamine, but it can be taken if prescribed by a doctor. However, if you experience abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, call a doctor. Do not discontinue any medication without consulting a doctor.
NaproxenPonatinib
Severe
How does the drug interact with Vasograin Plus Tablet:
Coadministration of Vasograin Plus Tablet and Ponatinib may increase the risk or severity of bleeding problems.

How to manage the interaction:
There may be a possible interaction between Vasograin Plus Tablet and Ponatinib, but they can be taken together if they are prescribed by doctor. However, if you experience unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness, consult the doctor. Do not discontinue any medication without a doctor's advice.
NaproxenTacrolimus
Severe
How does the drug interact with Vasograin Plus Tablet:
Coadministration of Vasograin Plus Tablet and Tacrolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
There may be a possible interaction between Vasograin Plus Tablet and Tacrolimus, but they can be taken together if they are prescribed by doctor. However, if you experience unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness lightheadedness red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds severe headache and weakness consult your doctor immediately. Do not discontinue any medication without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly as it helps in improving overall health and boosts self-esteem.

  • Avoid bright lights, loud noise, and extreme temperatures.

  • Perform meditation and yoga. This helps in relieving stress and provides relaxation.

  • Follow a regular sleep pattern to improve the amount and quality of sleep you get.

  • Massage your scalp to ease the pain.

  • Lie down in a quiet, dark room.

  • Place a cold cloth over your forehead or neck.

  • Avoid smoking, alcohol, and caffeinated drinks. 

  • Learn what triggers your migraine and try avoiding them.

  • Stay hydrated. Drink plenty of fluids.

  • Learn relaxation skills as they help in reducing stress.

Habit Forming

No

Therapeutic Class

ANTIMIGRAINE AGENTS

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Vasograin Plus Tablet 10's as it may cause increased drowsiness.

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Pregnancy

Caution

Vasograin Plus Tablet 10's should be used during the first and second trimesters of pregnancy only if the benefits outweigh the risks. Vasograin Plus Tablet 10's should not be taken during the third trimester of pregnancy.

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Breast Feeding

Caution

Vasograin Plus Tablet 10's may pass into breastmilk and harm the baby. Please consult your doctor before taking Vasograin Plus Tablet 10's; your doctor will decide whether Vasograin Plus Tablet 10's can be taken by breastfeeding mothers or not.

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Driving

Caution

Vasograin Plus Tablet 10's may cause dizziness, weakness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Vasograin Plus Tablet 10's should not be given to children as the safety and effectiveness were not established.

FAQs

Vasograin Plus Tablet 10's is used to prevent migraine symptoms such as headache, nausea, and vomiting.

Vasograin Plus Tablet 10's contains Sumatriptan and Naproxen. Sumatriptan acts on the serotonin (5-HT) receptors located in the brain; this causes the narrowing of the blood vessels in the brain and also affects the blood flow patterns associated with headaches. Naproxen works by blocking the effect of chemical messengers that cause pain.

Dry mouth could be a side-effect of Vasograin Plus Tablet 10's. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevents drying of the mouth.

Vasograin Plus Tablet 10's treats a headache that has already begun but does not prevent or reduce the attacks. Vasograin Plus Tablet 10's should not be used to treat cluster headache or other types of headache, which may cause loss of movement on one side of the body.

Vasograin Plus Tablet 10's contains Naproxen, an NSAID. Therefore, consult your doctor before taking any pain killer medicines, fever-reducing medicines, medicines for cold or sleeping problems along with Vasograin Plus Tablet 10's as they may also contain NSAID.

Talk to your doctor before taking Vasograin Plus Tablet 10's with anti-hypertensive medicines as they may cause impaired response when taken with painkiller. Regular monitoring of blood pressure levels is advised while taking Vasograin Plus Tablet 10's if you have high blood pressure. Vasograin Plus Tablet 10's should not be taken if you have uncontrolled high blood pressure.

Vasograin Plus Tablet 10's contains painkiller, which might increase the risk of gastrointestinal adverse effects such as ulceration, bleeding, and perforation of intestines or stomach. Therefore, consult your doctor if you have stomach ulcers.

Do not take a dose higher than the recommended dose of Vasograin Plus Tablet 10's. Taking more can lead to serious side effects like heart attack, stroke, bleeding, and stomach ulcers. Always follow your doctor's instructions. If your migraines persist, consult your doctor for a revised treatment plan to avoid harmful self-medication.

Store Vasograin Plus Tablet 10's in its original container, keeping it cool, dry, and out of sunlight. Keep it out of the reach of children. Regularly check the expiration date. When you need to dispose of the medicine, remove the label, place it in a plastic bag, and throw it away in the household trash. Remember, never flush the medicine down the toilet or sink to prevent harm to others and the environment.

Vasograin Plus Tablet 10's can cause sleepiness as a common side effect. Drowsiness affects up to 30% of naproxen users and 17% of sumatriptan users. Combining these medications may increase sedative effects. To minimize sleepiness, take the medication as directed, avoid operating heavy machinery or driving, and consider taking it at bedtime if prescribed once daily. If sleepiness persists or worsens, consult your doctor.

You can stop taking Vasograin Plus Tablet 10's once your migraine symptoms are relieved. However, always follow your doctor's instructions and consult them before stopping or adjusting the medication. If migraines persist, consult your doctor for further guidance.

Various factors, including stress, hormonal changes, certain foods, sleep disturbances, physical exertion, weather changes, and medical conditions can trigger migraines. Common triggers include chocolate, cheese, citrus fruits, bright lights, and loud noises. Identifying and managing your personal triggers can help reduce migraine frequency and severity.

The common side effects of Vasograin Plus Tablet 10's include dizziness, sleepiness, nausea, chest discomfort, dry mouth, irregular heartbeat, and heartburn. These side effects are usually mild and temporary, resolving as your body adjusts to the medication. However, if any side effects persist or worsen, it's essential to consult your doctor for proper guidance and care.

Vasograin Plus Tablet 10's should be used only during the first and second trimesters of pregnancy if the benefits outweigh the risks. Vasograin Plus Tablet 10's should not be taken during the third trimester of pregnancy.

Vasograin Plus Tablet 10's should not be given to children as safety and effectiveness were not established.

Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, and certain foods and drinks can trigger migraine headaches.

Taking more than the recommended dosage does not provide additional pain relief and can increase the risk of adverse effects.

Country of origin

India

Manufacturer/Marketer address

Sarkhej-Dholka Road, Bhat, Ahmedabad-382 210, India.
Other Info - VAS0508

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Sep 10, 2025 | 3:15 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021926s013lbl.pdf
  2. https://www.drugs.com/pregnancy/naproxen-sumatriptan.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021926s002lbl.pdf
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