Apollo
logo
Select Delivery Location
prescription
Prescription Medicine
info

Vaxenosetron 0.25 mg Injection 5 ml is used to prevent nausea and vomiting during chemotherapy. It contains Palonosetron, which blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone) located in the brain. Thus, it prevents nausea and vomiting. Common side effects of Vaxenosetron 0.25 mg Injection 5 ml are diarrhoea, constipation, dizziness or headache.

Read more
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get 18% Off with Coupons
coupon
Extra 10% Off with Bank Offers
bank offer
bank offer
bank offer

More about the Product

Composition :

PALONOSETRON-0.25MG

Manufacturer/Marketer :

Redvaxin (I) Pvt Ltd

Consume Type :

Parenteral

Return Policy :

Not Returnable

About Vaxenosetron 0.25 mg Injection 5 ml

Vaxenosetron 0.25 mg Injection 5 ml is an injection used to prevent nausea and vomiting caused by cancer chemotherapy or surgery. It belongs to a group of medicines that block signals in the body that trigger the vomiting reflex. By stopping these signals, it helps keep your stomach settled during critical medical treatments.

This medicine is injected by a healthcare professional as a single dose before your medical procedure or treatment begins. Because it is given in a clinical setting, you do not need to worry about keeping a daily schedule. Eating small, balanced meals and staying well-hydrated can also help support your overall recovery.

Most people tolerate this injection well, though some may experience mild side effects like a headache or constipation. If you develop serious symptoms such as a fast or irregular heartbeat, severe dizziness, or signs of a serious allergic reaction, tell your healthcare provider immediately.

Do not receive this medicine if you have had an allergic reaction to similar anti-nausea drugs in the past. Before starting, talk to your doctor if you have a history of heart rhythm disorders, severe liver damage, or an imbalance of minerals in your blood.

This medicine can interact with certain antidepressants, which can cause a rare but serious condition that affects your nervous system. Make sure to consult your doctor if you are pregnant, breastfeeding, or planning a pregnancy before receiving this injection.

Uses of Vaxenosetron 0.25 mg Injection 5 ml

Your doctor may prescribe Vaxenosetron 0.25 mg Injection 5 ml to help manage the following conditions:

  • Chemotherapy-induced nausea and vomiting: Helps prevent the feeling of sickness and throwing up both immediately after cancer chemotherapy and during the days following treatment.
  • Post-operative nausea and vomiting: Helps prevent nausea and throwing up that can occur after undergoing surgery under general anesthesia.

Key Benefits

When used as directed as part of your treatment plan, Vaxenosetron 0.25 mg Injection 5 ml may provide the following benefits:

  • Helps prevent nausea and vomiting: Reduces the chance of feeling sick or being sick during and after chemotherapy or surgery.
  • Provides long-lasting protection: Helps prevent both early and delayed nausea and vomiting, especially after certain types of chemotherapy.
  • Supports your recovery: By reducing nausea and vomiting, it may help you feel more comfortable while recovering from chemotherapy or surgery.
  • Helps you eat and drink more comfortably: Preventing nausea may make it easier to maintain your fluid intake and nutrition during recovery.
  • May improve your quality of life during treatment: Better control of nausea and vomiting can help you continue your daily activities and cancer treatment more comfortably.

Directions for Use

  • Vaxenosetron 0.25 mg Injection 5 ml is administered only in clinical settings by healthcare professionals, usually through intravenous or intramuscular injections.
  • The dosage and timing are decided by the doctor, depending on the cause and severity of symptoms.
  • Do not self-administer this medication.
  • Patients are monitored during and after administration to ensure safety and effective control of symptoms.

How Vaxenosetron 0.25 mg Injection 5 ml Works

Vaxenosetron 0.25 mg Injection 5 ml contains palonosetron. Palonosetron belongs to a group of medicines called 5-HT3 receptor antagonists (medicines that block serotonin signals that trigger nausea and vomiting). Chemotherapy and surgery can cause your body to release serotonin (a natural chemical), which attaches to 5-HT3 receptors (special proteins that receive signals) in the gut and brain. These signals can trigger nausea and vomiting. Palonosetron blocks these receptors, preventing serotonin from sending nausea and vomiting signals to the brain. This helps prevent nausea and vomiting before they start and provides long-lasting protection, particularly after chemotherapy.
bannner image

Alcohol

Caution

The interaction of alcohol with Vaxenosetron 0.25 mg Injection 5 ml is unknown. Please consult a doctor before consuming alcohol with Vaxenosetron 0.25 mg Injection 5 ml.

bannner image

Pregnancy

Consult your doctor

Vaxenosetron 0.25 mg Injection 5 ml is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please inform your doctor if you are pregnant.

bannner image

Breast Feeding

Consult your doctor

Please inform your doctor before taking Vaxenosetron 0.25 mg Injection 5 ml if you are breastfeeding. Vaxenosetron 0.25 mg Injection 5 ml is given to breastfeeding women only if the doctor thinks the benefits are greater than the risks.

bannner image

Driving

Caution

Vaxenosetron 0.25 mg Injection 5 ml may cause tiredness or dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel tired or dizzy after taking Vaxenosetron 0.25 mg Injection 5 ml.

bannner image

Liver

Safe if prescribed

Vaxenosetron 0.25 mg Injection 5 ml may be safe to use in patients with liver problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.

bannner image

Kidney

Safe if prescribed

Vaxenosetron 0.25 mg Injection 5 ml may be safe to use in patients with kidney problems if prescribed by a doctor. However, if you have any concerns regarding this, please discuss them with your doctor.

bannner image

Children

Caution

Vaxenosetron 0.25 mg Injection 5 ml may be given to children above 1 month in doses as advised by a doctor based on the child's body weight.

bannner image

Heart

Caution

If you have a pre-existing condition or a history of heart disease, inform your doctor before receiving Vaxenosetron 0.25 mg Injection 5 ml.

bannner image

Geriatrics

Consult your doctor

Please consult a doctor if you have any concerns regarding the use of Vaxenosetron 0.25 mg Injection 5 ml in elderly patients.

What if I have taken an overdose of Vaxenosetron 0.25 mg Injection 5 ml

Since this medication is prepared and injected by clinical professionals in a controlled medical setting, an overdose is extremely rare. However, if you suspect an overdose or experience severe symptoms like extreme dizziness or a rapid heartbeat, seek immediate medical attention.

Diet & Lifestyle Advise

  • Eat small, frequent meals: Eating smaller meals more often may help reduce nausea and make eating more comfortable.
  • Choose simple foods: Plain foods such as toast, rice, crackers, bananas, or porridge may be easier to tolerate. Avoid greasy, spicy, or very rich foods if they make your nausea worse.
  • Drink enough fluids: Sip water or other clear fluids regularly throughout the day to help prevent dehydration. If tolerated, ginger tea may also help relieve mild nausea.
  • Eat slowly and rest afterwards: Eat slowly and remain sitting upright for a while after meals to help digestion and reduce stomach discomfort.
  • Avoid strong smells: Cooking odours, perfumes, or cigarette smoke may trigger nausea in some people. Avoid them whenever possible.
health query

Have a query?

How Soon It Starts Working

The time required for Vaxenosetron 0.25 mg Injection 5 ml to start to work: Vaxenosetron 0.25 mg Injection 5 ml ideally shows its effects in 30 minutes. The time for which the effects of Vaxenosetron 0.25 mg Injection 5 ml last: Vaxenosetron 0.25 mg Injection 5 ml effect lasts for a few days.

What if you forget to take Vaxenosetron 0.25 mg Injection 5 ml

Because this medicine is injected by a healthcare professional right before a scheduled medical procedure, it is highly unlikely that you will miss a dose. If your treatment schedule changes or you believe a dose was missed, contact your healthcare provider immediately to reschedule.

Storage

•Keep the vial in its original carton to protect the solution from direct light. Do not freeze the medicine, as freezing can damage its effectiveness.

Drug Warnings

  • Tell your healthcare provider about all your medicines: This includes prescription medicines, over-the-counter medicines, vitamins, and herbal products, as some medicines may interact with Vaxenosetron 0.25 mg Injection 5 ml.
  • Report unusual symptoms immediately: Tell your healthcare provider straight away if you develop a rash, swelling, difficulty breathing, a fast or irregular heartbeat, severe dizziness, or fainting after receiving this medicine.
  • Be aware of serotonin syndrome: Seek medical help immediately if you develop symptoms such as agitation, confusion, shivering, fever, muscle twitching, or heavy sweating, especially if you also take antidepressants or other medicines that affect serotonin.
  • Tell your doctor if you have heart rhythm problems: Inform your doctor if you have a history of an irregular heartbeat, long QT syndrome (a heart rhythm disorder), or low potassium or magnesium levels before receiving this medicine.
  • Take care if you feel dizzy: If you feel dizzy or drowsy after receiving the injection, avoid driving, cycling, or operating machinery until you feel well again.
  • Tell your doctor if constipation becomes severe: Constipation can occur with this medicine. Seek medical advice if it is severe, persistent, or accompanied by abdominal pain or swelling.

verifiedApollotooltip
  • Antidepressants and other medicines that affect serotonin: Medicines such as SSRIs, SNRIs, MAOIs, or other medicines that increase serotonin may rarely increase the risk of serotonin syndrome (a serious condition caused by too much serotonin in the body). Tell your doctor immediately if you develop agitation, confusion, fever, heavy sweating, muscle twitching, or shivering.
  • Medicines that affect the heart rhythm: Some medicines used to treat irregular heart rhythms, certain antibiotics, antipsychotics, or other medicines that can prolong the QT interval (the time it takes the heart to recharge between beats) may increase the risk of abnormal heart rhythms when used together with Vaxenosetron 0.25 mg Injection 5 ml. Your doctor will decide if these medicines can be used safely together.
  • Other anti-sickness medicines: If you are receiving more than one medicine to prevent nausea and vomiting, your doctor will choose the combination that is most suitable for your treatment.

Login/Sign Up

verifiedApollotooltip
  • No clinically significant food interactions are known with Vaxenosetron 0.25 mg Injection 5 ml when used as directed.

Login/Sign Up

Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

FAQs

Vaxenosetron 0.25 mg Injection 5 ml is used to treat nausea and vomiting.
Vaxenosetron 0.25 mg Injection 5 ml contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
You are not recommended to take erythromycin with Vaxenosetron 0.25 mg Injection 5 ml as it may increase the risk of severe irregular heart rhythm. However, please consult your doctor before taking other medicines with Vaxenosetron 0.25 mg Injection 5 ml.
Vaxenosetron 0.25 mg Injection 5 ml may cause constipation as a side effect. It is not necessary for everyone taking Vaxenosetron 0.25 mg Injection 5 ml to experience this side effect. However, if the condition persists or worsens, please consult a doctor.
Vaxenosetron 0.25 mg Injection 5 ml should be used with caution in patients suffering from heart problems as it may worsen the condition. Therefore, inform your doctor if you have any heart problems before taking have Vaxenosetron 0.25 mg Injection 5 ml so that the dose may be adjusted appropriately.
It is given as an injection directly into a vein by a doctor or nurse in a medical clinic or hospital. Talk to your doctor if you have questions about the injection process.
Yes, it is designed to help prevent both immediate nausea and delayed nausea that can occur several days after receiving chemotherapy. Talk to your doctor for more information.
If you are pregnant or planning to become pregnant, you should discuss the risks and benefits with your doctor before receiving this injection. Talk to your doctor to find the best option for you.
While it is less likely to cause severe drowsiness than some older anti-nausea medicines, some people may still feel tired or weak after receiving it. Talk to your doctor if these symptoms persist.
This medicine can cause dizziness or fatigue in some patients. It is best to avoid driving or operating machinery until you know how the injection affects you. Talk to your doctor if you are unsure.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

SU-21, DDA Building, Madam Bhika Cama Place Bhawan,11 Bhikaji Cama Place,New Delhi,New Delhi,Delhi,110066-India
Other Info - VAX0057
whatsapp Floating Button
Buy Now
Add to Cart