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compositionComposition:PANITUMUMAB-100MG
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Prescription Medicine
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₹32627 with coupons & bank offers*

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Vectibix 100 mg Infusion 5 ml is used to treat Metastatic colorectal cancer (mCRC). It contains Panitumumab, which works by slowing or stopping the growth of cancer cells. As a result, it prevents the cancer from spreading. This medication may cause fetal harm when administered to a pregnant woman. Before beginning treatment, discuss effective contraception with your healthcare professional. Inform them immediately if you or your partner become pregnant while undergoing therapy. Breastfeeding is not recommended while taking Panitumumab.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
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More about the Product

Composition :

PANITUMUMAB-100MG

Manufacturer/Marketer :

GlaxoSmithKline Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Vectibix 100 mg Infusion 5 ml

Vectibix 100 mg Infusion 5 ml is a specialised medicine used to treat advanced bowel cancer (colorectal cancer) that has spread to other parts of the body. It is specifically designed for tumours that have a normal gene pattern known as RAS 'wild-type' and express a specific protein that helps cancer grow. This medicine is prescribed to slow down or stop the progression of the disease when other treatments have not worked or are being combined with it.

This medicine is given as a slow injection into a vein (an intravenous infusion) by a healthcare professional, usually once every two weeks. Because it is given in a clinical setting, your healthcare team will manage your schedule to ensure consistency. To support your body during treatment, it is highly recommended to stay well-hydrated, protect your skin from direct sunlight, and follow any specific dietary advice provided by your doctor.

Common side effects of Vectibix 100 mg Infusion 5 ml mostly affect the skin, causing acne-like rashes, dryness, and itching, as well as low levels of magnesium in the blood. You must contact your doctor immediately if you experience severe skin peeling, painful blistering, a sudden cough, or shortness of breath. Your healthcare team will monitor you closely during and after each session to manage these effects.

Talk to your doctor before starting Vectibix 100 mg Infusion 5 ml if you have a history of lung disease, severe skin conditions, or inflammatory bowel issues. Do not take this if you have had a severe, life-threatening allergic reaction to this medication in the past. Additionally, this medicine is not suitable for patients whose tumours have mutated RAS genes, especially when combined with certain chemotherapies, as it can cause harm.

Some medicines, including specific types of chemotherapy, can interact with Vectibix 100 mg Infusion 5 ml and increase the risk of severe side effects. It is also important to avoid alcohol and smoking, as they can worsen skin dryness and overall treatment tolerance. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor immediately, as this medicine can harm an unborn baby.

Uses of Vectibix 100 mg Infusion 5 ml

Vectibix 100 mg Infusion 5 ml is used to treat advanced bowel cancer (colorectal cancer). The detailed uses of Vectibix 100 mg Infusion 5 ml are as follows:

  • Advanced Bowel Cancer (Metastatic Colorectal Cancer): Vectibix 100 mg Infusion 5 ml is used to treat colorectal cancer that has spread to other organs. It is prescribed for tumours that test positive for the epidermal growth factor receptor (EGFR) and have normal (wild-type) RAS genes. It helps by targeting and blocking the signals that tell these cancer cells to grow.

Key Benefits

Vectibix 100 mg Infusion 5 ml helps patients by directly targeting cancer cells, which can offer several real-world benefits during advanced cancer care:

  • Slows Tumour Growth: By blocking growth signals, this medicine can help shrink tumours or stop them from spreading further.
  • Controls Symptoms: Helping to limit tumour progression can reduce cancer-related pain and physical discomfort, improving your daily comfort.
  • Works with Other Treatments: When used alongside chemotherapy, it can enhance the overall effectiveness of your cancer treatment plan.
Side effects of Vectibix 100 mg Infusion 5 ml
Managing Medication-Triggered Erythema (Redness of the Skin or Skin redness): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Know your allergens that cause dermatitis and avoid them.
  • Use fragrance-free detergents and soaps.
  • Apply moisturizer after taking bath to retain moisture in the skin.
  • Apply cool, moist compresses to the rash.
  • Talk to your doctor about creams and ointments to manage your dermatitis.
  • Avoid the use of abrasive scrubs, astringents, and soaps that might irritate skin.
  • Contact a physician or dermatologist to treat any medical concerns if the skin symptoms worsen or continue.
  • Drink enough water throughout the day to maintain hydrated, plump skin.
  • If the skin symptoms persist or worsen, consult a doctor or dermatologist
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Soak the infected nail in warm water for 10 to 20 minutes, a few times a day.
  • Apply topical antibiotic ointment as advised by the doctor.
  • Avoid irritants and excessive moisture.
  • Maintaining adequate hydration will help you control your magnesium levels and improve your general health.
  • Maintain a diet high in magnesium-rich foods such as spinach, almonds, chickpeas and brown rice.
  • Limit your alcohol intake because too much of it lowers your magnesium levels.
  • Plan blood testing on a regular basis to monitor magnesium levels.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Vectibix 100 mg Infusion 5 ml will be administered by your doctor.
  • Avoid self-administration.

How Vectibix 100 mg Infusion 5 ml Works

Vectibix 100 mg Infusion 5 ml contains panitumumab, which is a monoclonal antibody, which is a type of targeted protein. It works by finding and locking onto a specific protein called Epidermal Growth Factor Receptor (EGFR) found on the surface of certain cancer cells. Normally, when natural proteins bind to EGFR, they send signals telling the cancer cell to grow and divide. By blocking this receptor, Vectibix 100 mg Infusion 5 ml cuts off these growth signals, which helps slow down, stop, or even reverse tumour growth.
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Alcohol

Unsafe

Do not consume alcohol while on treatment with Vectibix 100 mg Infusion 5 ml.

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Pregnancy

Unsafe

Vectibix 100 mg Infusion 5 ml is not recommended for use during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception for at least two months from the last dose of medicine to prevent pregnancy while taking these medications.

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Breast Feeding

Unsafe

Do not breastfeed your baby during the period over which you are being treated with Vectibix 100 mg Infusion 5 ml and for two months after the last dose.

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Driving

Caution

Vectibix 100 mg Infusion 5 ml will be administered to hospitalized patients. Hence, driving is not recommended.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Vectibix 100 mg Infusion 5 ml. Your doctor will weigh the benefits and potential risks before prescribing Vectibix 100 mg Infusion 5 ml.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Vectibix 100 mg Infusion 5 ml. Your doctor may titrate the dose if required based on your condition.

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Children

Caution

The safety and effectiveness of Vectibix 100 mg Infusion 5 ml in children have not been established.

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Heart

Consult your doctor

Vectibix 100 mg Infusion 5 ml should be avoided in individuals with heart problems due to potential cardiac risks. Always consult your doctor to explore safer treatment options tailored to your condition.

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Geriatrics

Safe if prescribed

Vectibix 100 mg Infusion 5 ml can be used in geriatric patients, and studies have not shown age-specific limitations to its effectiveness. However, older adults may be more prone to side effects like diarrhea or skin reactions, so careful monitoring is advised during treatment. Always consult your doctor to weigh the risks and benefits based on your overall health.

What if I have taken an overdose of Vectibix 100 mg Infusion 5 ml

Since this medication is prepared and given by trained medical professionals, an overdose is highly unlikely. However, if you suspect an error or experience severe side effects immediately after an infusion, seek emergency medical help right away.

Diet & Lifestyle Advise

  • Protect Your Skin: Apply an alcohol-free, gentle moisturiser to your face and body daily, starting before your first treatment. Wear a broad-spectrum sunscreen (SPF 30 or higher) and protective clothing whenever you go outside, as this medicine makes your skin highly sensitive to sunlight.
  • Eat Magnesium-Rich Foods: Since Vectibix 100 mg Infusion 5 ml can lower your magnesium levels, incorporate foods like spinach, almonds, black beans, and avocados into your diet, as advised by your doctor.
  • Stay Well-Hydrated: Drink plenty of water throughout the day to help your kidneys function well and to manage dryness or mild diarrhoea.
  • Avoid Harsh Skin Products: Do not use anti-acne products that contain benzoyl peroxide or salicylic acid, as they can severely irritate the skin rash caused by this medicine.
health query

Have a query?

How Soon It Starts Working

The time required for Vectibix 100 mg Infusion 5 ml to start to work: The time required for Vectibix 100 mg Infusion 5 ml to show its action is not clinically established. The time for which the effects of Vectibix 100 mg Infusion 5 ml last: The duration of action for Vectibix 100 mg Infusion 5 ml is not clinically established.

What if you forget to take Vectibix 100 mg Infusion 5 ml

Because this medicine is given by a healthcare provider at a clinic, missing a dose usually means missing an appointment. Contact your doctor or cancer clinic immediately to reschedule your infusion. Do not attempt to double the dose at your next visit.

Storage

• It must be kept in a refrigerator between 2°C and 8°C.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect Your Skin Daily: Tell your healthcare team about any new skin redness, rash, or peeling immediately, as early treatment can prevent the rash from becoming severe.
  • Complete Your Genetic Testing: Ensure your doctor has confirmed your tumour has 'wild-type' (normal) RAS genes before starting therapy, as this medicine is not effective for mutated RAS tumours.
  • Avoid Sunbathing: Keep out of direct sunlight and avoid tanning beds entirely during treatment and for at least two months after your final dose.
  • Watch for Eye Irritation: If you wear contact lenses, ask your doctor if you should switch to glasses, as this medicine can cause dry eyes and corneal inflammation.
  • Monitor Your Infusion Site: Tell the nurse immediately if you feel pain, burning, or swelling around the injection site during your infusion.

Drug-Drug Interactions

verifiedApollotooltip
  • Certain Chemotherapy Regimens (e.g., Bevacizumab combinations): Combining Vectibix 100 mg Infusion 5 ml with certain other cancer drugs may significantly increase the risk of severe skin toxicity, diarrhoea, and infections.
PanitumumabAmiodarone
Severe

Drug-Drug Interactions

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PanitumumabAmiodarone
Severe
How does the drug interact with Vectibix 100 mg Infusion 5 ml:
Coadministration of Amiodarone together with Vectibix 100 mg Infusion 5 ml may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Vectibix 100 mg Infusion 5 ml interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Vectibix 100 mg Infusion 5 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[MONOCLONAL ANTIBODIES]

FAQs

Vectibix 100 mg Infusion 5 ml is used to treat Metastatic colorectal cancer (mCRC).
Vectibix 100 mg Infusion 5 ml contains Panitumumab, which works by slowing or stopping the growth of cancer cells. Thus, it prevents the cancer from spreading.
Attend all your doctor's appointments while receiving Vectibix 100 mg Infusion 5 ml to ensure the therapy is effective. Regular blood tests and weight checks must be performed. While taking the Vectibix 100 mg Infusion 5 ml, both men and women should use an effective means of contraception. Do not use any other medications unless prescribed by the doctor.
Magnesium and calcium levels in the blood may significantly fall as a result of Panitumumab. Laboratory testing may be recommended by your doctor both before and during treatment.
Vectibix 100 mg Infusion 5 ml is given as an intravenous (IV) infusion (a slow drip into a vein) by a healthcare professional in a clinic or hospital setting. Talk to your doctor if you have questions about your infusion schedule.
Yes, skin rashes are a very common side effect. They often look like acne and can be itchy or dry. Talk to your doctor or pharmacist about safe moisturisers to use during treatment.
This medicine only works effectively on tumours that have normal (wild-type) RAS genes. A genetic test ensures that Vectibix 100 mg Infusion 5 ml is the right and safe choice for your specific cancer type. Talk to your doctor to learn more.
Drink plenty of clear fluids to stay hydrated and contact your healthcare provider. They can recommend safe anti-diarrhoea medications or adjust your treatment plan. Talk to your doctor before taking any over-the-counter remedies.
You must limit your sun exposure, as Vectibix 100 mg Infusion 5 ml makes your skin highly sensitive to UV rays. Wear protective clothing, hats, and sunscreen with a high SPF whenever you are outdoors. Talk to your pharmacist for product recommendations.
Yes, this medicine can cause your body to lose magnesium, which can lead to fatigue or muscle cramps. Your doctor will monitor your blood levels regularly and may prescribe magnesium supplements. Talk to your doctor if you experience muscle weakness.
No, this medicine can harm an unborn baby. Women who can become pregnant must use effective birth control during treatment and for at least two months after the last dose. Talk to your doctor about safe family planning options.
Severe skin reactions and lung inflammation are among the most serious risks. Seek immediate medical attention if you experience breathing difficulties, a sudden cough, or severe blistering and peeling of the skin. Talk to your doctor for a complete list of warning signs.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

24-25 Floor, One Horizon Center Golf Course Road, Dlf Phase 5 Gurgaon 122002, India.
Other Info - VEC0029
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