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compositionComposition:APREPITANT-205MG
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Prescription Medicine
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Vexapitant 125/80 Kit Capsule 3's is used to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. It contains Aprepitant, a neurokinin 1 (NK1) receptor antagonist which works by blocking the neurokinin-1 receptor (causes the feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

APREPITANT-205MG

Manufacturer/Marketer :

Redvaxin (I) Pvt Ltd

Consume Type :

Oral

Return Policy :

Not Returnable

About Vexapitant 125/80 Kit Capsule 3's

Vexapitant 125/80 Kit Capsule 3's is a prescription medicine used to prevent nausea and vomiting that may be caused by cancer chemotherapy treatments. It is also prescribed to prevent nausea and vomiting that can occur after surgical procedures under general anesthesia. This medicine is used as a preventive measure and is not intended to treat nausea or vomiting that has already started.

This medication is typically taken as a short-term course, starting shortly before your treatment or surgery. To achieve the best results, it is crucial to take Vexapitant 125/80 Kit Capsule 3's exactly as scheduled by your doctor, even if you are not currently feeling sick. You can take this medicine with or without food, swallowing the capsule whole with a glass of water. Adopting a diet of bland, small meals and maintaining proper hydration can also significantly support your recovery.

Some patients taking Vexapitant 125/80 Kit Capsule 3's may experience mild side effects, such as hiccups, fatigue, or indigestion. While these symptoms are generally mild, you must contact your healthcare provider immediately if you experience serious side effects like severe dizziness, skin rashes, or difficulty breathing. Always report any unusual or worsening symptoms to your medical team right away.

Before starting Vexapitant 125/80 Kit Capsule 3's, it is important to inform your doctor if you have a history of liver damage, as this organ processes the medicine. Do not take this medicine if you are allergic to any of its components or if you are currently taking medications like pimozide, cisapride, or terfenadine, as this can cause dangerous health risks.

This medication can interact with other substances, including hormonal contraceptives, which may make your birth control less effective during treatment. It is also important to consult your healthcare provider if you are pregnant, planning a pregnancy, or breastfeeding to evaluate the safety of this medicine for you. Additionally, avoid drinking alcohol or smoking while taking this medicine, as they can worsen stomach irritation and increase tiredness.

Uses of Vexapitant 125/80 Kit Capsule 3's

A healthcare professional may prescribe Vexapitant 125/80 Kit Capsule 3's to prevent nausea and vomiting associated with medical treatments and surgery. These include:

  • Chemotherapy-induced nausea and vomiting: Vexapitant 125/80 Kit Capsule 3's is used to prevent both the immediate and delayed nausea and vomiting associated with cancer chemotherapy treatments.
  • Postoperative nausea and vomiting: Vexapitant 125/80 Kit Capsule 3's helps prevent nausea and vomiting that can occur when waking up from general anesthesia after a surgical procedure.

Key Benefits

Vexapitant 125/80 Kit Capsule 3's helps prevent nausea and vomiting, making cancer treatment and recovery after surgery more comfortable. Key benefits include:

  • Prevents nausea and vomiting: Vexapitant 125/80 Kit Capsule 3's provides significant relief by helping to control the physical triggers that cause nausea, allowing you to undergo chemotherapy or surgery with greater physical comfort. By preventing severe nausea and vomiting, this medication helps you maintain your regular nutrition and fluid intake during critical treatment periods.
  • Provides long-lasting protection: Another key benefit is its long-lasting action, which helps prevent delayed nausea that often occurs several days after chemotherapy. This continuous protection supports a smoother, faster recovery process and reduces the need for emergency medical care for dehydration.

Directions for Use

  • Vexapitant 125/80 Kit Capsule 3's can be taken with or without food because food does not impact its effectiveness.
  • It is usually taken once a day; however, follow your doctor’s advice regarding the dosage and duration.
  • Swallow Vexapitant 125/80 Kit Capsule 3's as a whole with a glass of water.
  • Do not break, chew, or crush it.

How Vexapitant 125/80 Kit Capsule 3's Works

Vexapitant 125/80 Kit Capsule 3's contains aprepitant. During treatments like chemotherapy or major surgery, the body releases a chemical messenger called substance P in the brain and gut. When substance P attaches to specific receptors, known as neurokinin-1 (NK1) receptors, it sends strong signals that trigger the vomiting reflex and cause feelings of intense nausea. Vexapitant 125/80 Kit Capsule 3's works as an NK1 receptor blocker. It binds tightly to these specific receptors in the brain and nervous system, preventing substance P from attaching to them. By blocking these signals, the medication effectively shuts down the communication pathway that triggers nausea and vomiting, helping to prevent these symptoms from developing.
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Alcohol

Consult your doctor

The interaction of alcohol with Vexapitant 125/80 Kit Capsule 3's is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before taking Vexapitant 125/80 Kit Capsule 3's. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Consult your doctor

It is unknown whether Aprepitant is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before taking Vexapitant 125/80 Kit Capsule 3's.

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Driving

Caution

Vexapitant 125/80 Kit Capsule 3's may cause dizziness or drowsiness in some people. Hence, do not drive or operate machinery if you feel dizzy or drowsy after taking Vexapitant 125/80 Kit Capsule 3's.

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Liver

Caution

If you have liver disease, inform your doctor before taking Vexapitant 125/80 Kit Capsule 3's. Your doctor may monitor your liver condition.

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Kidney

Consult your doctor

If you have any kidney problems, inform your doctor before taking Vexapitant 125/80 Kit Capsule 3's.

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Children

Unsafe

Vexapitant 125/80 Kit Capsule 3's is not recommended for children below 12 years of age.

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Heart

Consult your doctor

Please consult your doctor before receiving Vexapitant 125/80 Kit Capsule 3's if you have pre-existing heart problems. Your doctor will prescribe Vexapitant 125/80 Kit Capsule 3's if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available about the use of Vexapitant 125/80 Kit Capsule 3's in geriatric patients. Please consult your physician.

What if I have taken an overdose of Vexapitant 125/80 Kit Capsule 3's

If you suspect an accidental overdose, seek emergency medical care immediately. Watch for symptoms such as extreme fatigue or a severe headache.

Diet & Lifestyle Advise

  • Eat small, frequent meals: Eat small, frequent meals throughout the day rather than three large meals to reduce pressure on your stomach.
  • Choose bland foods: Choose dry, bland foods like crackers, toast, plain rice, or oatmeal, and avoid greasy, fried, spicy, or very sweet foods that can trigger nausea.
  • Stay hydrated: Drink clear liquids, such as water, clear broths, or ginger tea, in small sips throughout the day. Try to drink fluids between meals instead of during meals.
  • Avoid lying down after eating: Avoid lying down completely flat for at least 30–60 minutes after eating to help prevent acid reflux and nausea.
  • Avoid strong smells: Sit in a well-ventilated room with fresh air, and avoid strong cooking smells or perfumes that can stimulate the vomiting reflex.
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Have a query?

How Soon It Starts Working

The time required for Vexapitant 125/80 Kit Capsule 3's to start to work: The onset of time for Vexapitant 125/80 Kit Capsule 3's is unknown. The time for which the effects of Vexapitant 125/80 Kit Capsule 3's last: The duration of Vexapitant 125/80 Kit Capsule 3's effect is unknown.

What if you forget to take Vexapitant 125/80 Kit Capsule 3's

If you miss a dose of Vexapitant 125/80 Kit Capsule 3's, contact your doctor or pharmacist immediately to get instructions on what to do. Do not take a double dose to make up for a missed one, as this is a highly scheduled preventive therapy.

Storage

• Store Vexapitant 125/80 Kit Capsule 3's oral capsules at room temperature, between 20°C and 25°C.

Drug Warnings

  • Check the medicine pack: Always check your medicine pack before use to ensure the blister seal is fully intact and undamaged.
  • Use backup contraception: This medicine can significantly reduce the effectiveness of hormonal contraceptives, such as birth control pills, patches, or implants. Use a reliable non-hormonal backup method, such as condoms, while taking this medicine and for 28 days after your final dose.
  • Monitor blood clotting: If you take blood thinners such as warfarin, your doctor may perform extra blood tests to monitor your blood clotting levels after you complete treatment.
  • Avoid driving if affected: Do not drive, operate heavy machinery, or perform hazardous tasks if you feel dizzy or unusually tired after taking this medicine.
  • Inform your healthcare team: Make sure your healthcare team has a complete list of all medicines you take, including prescription medicines, over-the-counter products, and herbal supplements, before you start treatment.

verifiedApollotooltip
  • Hormonal Contraceptives: May decrease the effectiveness of birth control pills, patches, or rings.
  • Blood Thinners (such as Warfarin): May reduce the effect of the blood thinner, requiring close monitoring of your blood clotting times.
  • Certain Anti-seizure Medications (such as Carbamazepine, Phenytoin): May lower the levels of Vexapitant 125/80 Kit Capsule 3's in your body, making it less effective.
  • Certain Antifungals and Antibiotics (such as Ketoconazole, Clarithromycin): May increase the levels of Vexapitant 125/80 Kit Capsule 3's in your blood, increasing the risk of side effects.

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verifiedApollotooltip
  • Grapefruit and Grapefruit Juice: Consuming grapefruit products can increase the levels of Vexapitant 125/80 Kit Capsule 3's in your system, raising your risk of side effects. Avoid these products during your treatment.

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Habit Forming

No

Therapeutic Class

[ANTIEMETICS]

FAQs

Vexapitant 125/80 Kit Capsule 3's is used to treat Chemotherapy-induced nausea and vomiting.
Vexapitant 125/80 Kit Capsule 3's works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.
You are not recommended to take erythromycin with Vexapitant 125/80 Kit Capsule 3's as it may increase the blood levels and effects of Vexapitant 125/80 Kit Capsule 3's. Contact your doctor if your condition changes or experience side effects such as diarrhoea, constipation, nausea, or loss of appetite. However, please consult your doctor before taking other medicines with Vexapitant 125/80 Kit Capsule 3's.
No, Vexapitant 125/80 Kit Capsule 3's is a preventive medication and must be taken before you start feeling sick to be effective. It is not designed to stop active vomiting that has already started. Talk to your doctor for options if you are currently vomiting.
Yes, fatigue and sleepiness are known side effects for some patients taking this medicine. Avoid activities that require mental alertness, like driving, if you feel tired. Talk to your doctor if this tiredness persists or worsens.
You should take your first dose of Vexapitant 125/80 Kit Capsule 3's before your chemotherapy session or surgery begins, exactly at the time directed by your healthcare team. Talk to your doctor if you are unsure about your exact dosing timeline.
Yes, you can take this medicine with or without food. Be sure to swallow the capsule whole with water. Talk to your doctor or pharmacist if you have questions about taking your dose.
Yes. Vexapitant 125/80 Kit Capsule 3's can make hormonal birth control methods, including birth control pills, implants, skin patches, and certain intrauterine devices (IUDs), less effective during treatment and for up to 2 months after your last dose. You should use a non-hormonal backup method, such as condoms, during this time. Talk to your doctor about the most appropriate birth control options for you.
If you throw up shortly after taking your dose, do not take an extra capsule on your own. Contact your healthcare team immediately for guidance on what to do next. Talk to your doctor for specific advice.
It is best to avoid alcohol while taking this medicine, as alcohol can increase side effects like dizziness and drowsiness and can irritate your stomach. Talk to your doctor if you have questions about alcohol use.
The safety of this medicine during pregnancy is not fully known, and it should only be used if absolutely necessary. Talk to your doctor to discuss the potential benefits and risks before starting this treatment.

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Country of origin

India

Manufacturer/Marketer address

SU-21, DDA Building, Madam Bhika Cama Place Bhawan,11 Bhikaji Cama Place,New Delhi,New Delhi,Delhi,110066-India
Other Info - VEX0036
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