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VIROTRENZ TABLET is used to treat HIV infection. It works by inhibiting the reverse transcriptase enzyme production, which is necessary for viral reproduction. In some cases, this medicine may cause side effects such as headache, dizziness, diarrhoea, nausea, and vomiting. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

EFAVIRENZ-600MG+EMTRICITABINE-200MG+TENOFOVIR DISOPROXIL-300MG

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About VIROTRENZ TABLET

VIROTRENZ TABLET is a prescription tablet used to manage Human Immunodeficiency Virus type 1 (HIV-1) infection in adults and adolescents. It combines three antiviral agents into a single medication to help control the replication of the virus in your body. By keeping the viral load low, it helps protect your immune system from damage and prevents the disease from progressing. Your doctor will choose the most appropriate HIV treatment based on current treatment guidelines, your medical history, and the results of any necessary tests.

To achieve the best results, you must take VIROTRENZ TABLET consistently once every day at the exact same time without missing doses. It is best to take this tablet on an empty stomach, ideally right before bedtime, to minimise certain brain-related side effects. Adopting a nutritious diet, maintaining regular exercise, and avoiding smoking can significantly boost your overall health and treatment success.

While starting this therapy, you may notice mild side effects such as temporary dizziness, trouble sleeping, or mild nausea. However, you must contact your doctor immediately if you develop serious symptoms such as a severe skin rash, persistent low mood, or yellowing of the skin and eyes.

Before you begin taking VIROTRENZ TABLET, tell your doctor if you have liver disease, including hepatitis B, kidney disease, or mental health problems. If you have hepatitis B, your doctor may monitor you closely because stopping this medicine can cause your liver condition to worsen.

This medicine can interact negatively with alcohol, certain herbal products, and other prescription medications, potentially lowering its effectiveness or increasing side effects. Pregnant individuals, breastfeeding mothers, or elderly patients must consult their healthcare provider before using this medicine to ensure it is safe for them.

Uses of VIROTRENZ TABLET

VIROTRENZ TABLET is used to treat HIV-1 infection in treatment-naive patients and in certain people who are changing treatment, as decided by their doctor. It helps control the virus and protect the immune system. It may be prescribed for:

  • HIV-1 Infection: VIROTRENZ TABLET is used to treat HIV-1 by keeping the virus at extremely low levels in the blood, which prevents the virus from damaging your immune cells.
  • Immune System Preservation: By controlling the viral multiplication, this medication allows your body to maintain or increase its CD4 cell count, protecting you against opportunistic infections.
     

Key Benefits

VIROTRENZ TABLET helps control HIV-1 infection by reducing the amount of virus in the body. Its benefits include:

  • Suppresses HIV Replication: Helps reduce the amount of HIV in the body (viral load), allowing the immune system to function more effectively.
  • Supports Immune Health: By controlling HIV infection, it helps preserve and improve immune function, reducing the risk of opportunistic infections and HIV-related illnesses.
  • Provides Complete Combination Therapy: Combines three antiretroviral medicines in a single tablet, providing comprehensive HIV treatment in one regimen.
  • Simplifies Daily Treatment: The once-daily, single-tablet regimen helps reduce pill burden and supports long-term treatment adherence.
  • Reduces the Risk of HIV Transmission: Maintaining an undetectable viral load through consistent treatment greatly reduces the risk of sexually transmitting HIV to others, although it does not eliminate the need for appropriate preventive measures.
     

Directions for Use

  • VIROTRENZ TABLET should be taken on an empty stomach 1 hour before or 2 hours after a meal, preferably at bedtime, or as prescribed by the doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow it as a whole with a glass of water.
  • Do not chew, crush or break it.

How VIROTRENZ TABLET Works

VIROTRENZ TABLET contains efavirenz, emtricitabine, and tenofovir disoproxil, which work together to disrupt the life cycle of the HIV-1 virus and stop it from making copies of itself inside your body. Two of the active ingredients, emtricitabine and tenofovir disoproxil, belong to a class of medicines called nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs). Once inside your cells, they mimic natural building blocks that the virus tries to use to build its DNA. When the virus uses these mock building blocks, its DNA chain is cut short, stopping replication. The third active ingredient, efavirenz, belongs to a class called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It directly binds to and blocks the enzyme the virus uses to duplicate itself. Together, these actions help prevent the HIV-1 virus from multiplying and spreading to new immune cells.
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Alcohol

Caution

Consumption of alcohol may increase the risk of side-effects.

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Pregnancy

Caution

VIROTRENZ TABLET should be used with caution in pregnant women. It is given only if clinically needed and when benefits outweigh the risk.

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Breast Feeding

Caution

VIROTRENZ TABLET should be used with caution in breastfeeding women. If VIROTRENZ TABLET is prescribed during breastfeeding, the doctor may advise you to stop breastfeeding as this medicine can pass into breastmilk.

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Driving

Caution

VIROTRENZ TABLET may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

VIROTRENZ TABLET should not be used with caution in patients with severe liver diseases. In mild to moderate conditions, the dose may have to be adjusted by your doctor as required.

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Kidney

Caution

VIROTRENZ TABLET should not be used in patients with moderate to severe kidney diseases as this medicine may affect kidney function. In mild conditions, the dose may have to be adjusted by your doctor as required.

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Children

Unsafe

VIROTRENZ TABLET is not recommended for use in children and adolescents below 18 years.

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Heart

Caution

VIROTRENZ TABLET should be taken with caution in patients with heart problems. Therefore, please inform your doctor before using VIROTRENZ TABLET.

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Geriatrics

Caution

VIROTRENZ TABLET should be given with caution in elderly patients due to an increased risk of side effects. Please inform your doctor before use.

What if I have taken an overdose of VIROTRENZ TABLET

If you take more than your prescribed dose of VIROTRENZ TABLET, seek immediate medical attention or call your local poison control centre, even if you do not notice any symptoms. Symptoms of an overdose may include extreme dizziness, confusion, or a rapid heart rate.

Diet & Lifestyle Advise

  • Avoid high-fat meals: Consuming high-fat food near your dosing time can significantly increase the levels of the medicine in your blood, raising the risk of severe central nervous system side effects.
  • Drink plenty of fluids: Stay well-hydrated throughout the day. This helps your kidneys process and eliminate the medication safely, reducing the risk of kidney strain.
  • Limit alcohol intake: Alcohol can put extra stress on your liver and worsen side effects like dizziness, drowsiness, and difficulty concentrating.
  • Support your immune system: Focus on a balanced diet rich in clean proteins, vegetables, and fruit, and practice safe hygiene to protect your body from infections.
     
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Have a query?

How Soon It Starts Working

The time required for VIROTRENZ TABLET to start to work: The time required for VIROTRENZ TABLET to show its action is unknown. The time for which the effects of VIROTRENZ TABLET last: The duration of action for VIROTRENZ TABLET is clinically unknown.

What if you forget to take VIROTRENZ TABLET

If you miss a dose of VIROTRENZ TABLET, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure what to do, talk to your doctor or pharmacist.

Storage

•Store VIROTRENZ TABLET tablets in their original container at room temperature, ideally between 68°F and 77°F (20°C to 25°C). •Keep the bottle tightly closed and store it away from moisture, direct heat, and light. Avoid storing this medication in humid areas lik

Drug Warnings

  • Do not stop taking suddenly: Stopping this medicine abruptly can cause the virus to quickly multiply and become resistant, making future treatments less effective.
  • Check your hepatitis B status: Ensure your doctor tests you for Hepatitis B before starting. Stopping VIROTRENZ TABLET if you have Hepatitis B can trigger a sudden, severe liver flare-up.
  • Avoid driving if dizzy: Because this medicine can cause drowsiness, dizziness, and trouble concentrating, do not drive or operate machinery until you know how it affects you.
  • Use reliable birth control: This medication may cause harm to an unborn baby during early pregnancy. Talk to your doctor about effective barrier methods of contraception.
  • Look after your bone health: The tenofovir disoproxil component may affect bone strength in some people during long-term treatment. Your doctor may recommend monitoring your bone health if needed.
  • Keep up with lab tests: Your doctor may recommend tests before starting treatment to help choose the most appropriate HIV medicine and monitor how well it continues to work. Attend all your scheduled blood tests so your doctor can regularly check your kidney function, liver health, and viral levels.
     

Drug-Drug Interactions

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  • Other antiviral medications: Taking this with other HIV drugs that contain the same active ingredients can cause an accidental overdose.
  • Tuberculosis and bacterial medications: Rifampin can significantly lower the levels of VIROTRENZ TABLET in your body, making it less effective.
  • Seizure medications: Anticonvulsants like carbamazepine or phenytoin can reduce the absorption and effectiveness of this treatment.
  • Hormonal contraceptives: The efavirenz component may reduce the effectiveness of some hormonal contraceptives. Your doctor may recommend an additional or alternative method of contraception.
  • Methadone: This medicine may reduce the effectiveness of methadone. Tell your doctor if you notice withdrawal symptoms or changes in how well your treatment is working.
  • Antifungal medicines: Some antifungal medicines, such as voriconazole, may interact with VIROTRENZ TABLET. Tell your doctor about all medicines you are taking before starting treatment.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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  • High-fat meals: Eating a high-fat meal close to your dose can increase the absorption of the efavirenz component, making side effects such as dizziness, drowsiness, or vivid dreams more likely.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIRETROVIRAL AGENTS]

FAQs

VIROTRENZ TABLET is used to treat HIV infection.
VIROTRENZ TABLET contains Efavirenz, Emtricitabine, and Tenofovir. Efavirenz is a non-nucleoside reverse transcriptase inhibitor, whereas Emtricitabine and Tenofovir are nucleotide reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme production, which the HIV-infected cells must make to make new viruses. This effect helps to inhibit viral replication.
VIROTRENZ TABLET should be taken on an empty stomach 1 hour before or 2 hours after a meal, preferably at bedtime, as this medicine may cause dizziness or drowsiness.
The common side-effects of VIROTRENZ TABLET are dizziness, headache, diarrhea, feeling sick (nausea), being sick (vomiting), rashes (red spots or blotches sometimes with blistering and swelling of the skin), and feeling weak. These side-effects usually resolve without requiring any medical attention. However, if any of these side effects persist or get worse, inform your doctor immediately.
VIROTRENZ TABLET should not be given to patients with severe liver disease, moderate to severe kidney disease, heart condition such as prolongation of the QT interval which increases the risk of severe heart rhythm problems, family history of heart problems, and low electrolyte levels.
VIROTRENZ TABLET doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.
No, you should take VIROTRENZ TABLET on an empty stomach, preferably at bedtime. Taking it with food, especially high-fat meals, can cause too much of the medicine to enter your blood, which increases the risk of severe side effects like dizziness and confusion. Talk to your doctor or pharmacist if you struggle with this schedule.
Vivid dreams and difficulty sleeping are common when first starting VIROTRENZ TABLET. Taking the medicine right before you go to sleep on an empty stomach usually helps reduce these effects, and they often improve after a few weeks. If they continue to bother you, talk to your doctor.
You should avoid or strictly limit alcohol while taking VIROTRENZ TABLET. Alcohol can increase your risk of liver damage and worsen central nervous system side effects such as drowsiness, dizziness, and poor concentration. Talk to your doctor about your alcohol use.
Missing doses can allow the virus to start reproducing again and quickly develop resistance to VIROTRENZ TABLET, meaning the medication may stop working for you entirely. If you have missed doses, do not double your dose; talk to your doctor or pharmacist immediately for advice.
Yes, in some patients, components of VIROTRENZ TABLET can cause kidney strain or damage. Your doctor will monitor your kidney function through regular blood and urine tests while you are on this therapy. Talk to your doctor if you notice changes in your urination or swelling in your legs.
The efavirenz component may pose a risk to an unborn baby, particularly during early pregnancy. If you are pregnant, planning to become pregnant, or think you might be, talk to your doctor before taking this medicine so they can recommend the most appropriate treatment.
Some supplements, like St. John's Wort, or certain pain medications can interact negatively with VIROTRENZ TABLET or stress your kidneys further. Always talk to your doctor or pharmacist before starting any new over-the-counter medications, vitamins, or herbal products.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - VIR0027
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