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compositionComposition:CANAGLIFLOZIN-50MG+METFORMIN-1000MG
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Prescription Medicine
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Vokanamet 50/1000 Tablet is used to treat type 2 diabetes mellitus. It contains Metformin and Canagliflozin which reduce increased blood glucose levels by eliminating excess sugars from the body through urine. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, gas, headache, weakness, frequent urination and indigestion. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CANAGLIFLOZIN-50MG+METFORMIN-1000MG

Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Vokanamet 50/1000 Tablet

Vokanamet 50/1000 Tablet is a prescription medication used to manage blood sugar levels in adults with type 2 diabetes. It serves as an important therapeutic option when lifestyle changes like diet and exercise alone do not provide adequate glycemic control. By keeping blood sugar levels within a healthy range, it helps lower the risk of serious long-term complications associated with diabetes.

For this medication to work effectively, you must take it consistently every day at the same time, exactly as directed by your doctor. It is typically taken with meals to reduce the likelihood of stomach upset. To achieve the best results, you should use this medication in combination with a balanced diet low in simple carbohydrates and regular, moderate physical exercise.

While taking Vokanamet 50/1000 Tablet , you may experience mild and manageable side effects such as temporary stomach discomfort or an increased need to urinate. However, you must contact your doctor immediately if you experience serious symptoms like extreme weakness, breathing difficulties, severe abdominal pain, or signs of a severe urinary tract infection.

Talk to your doctor before starting this medication if you have a history of kidney disease, liver problems, heart failure, or frequent urinary tract infections. Do not take this if you have severe kidney impairment, are on dialysis, or have a history of diabetic ketoacidosis or metabolic acidosis.

This medicine can interact with other treatments, such as water pills or blood pressure medications, which may require your doctor to adjust your therapy. Limit or avoid alcohol while taking this medicine, as alcohol increases the risk of serious metabolic complications. If you are pregnant, breastfeeding, or are an older adult, consult your healthcare provider to discuss whether this medication is appropriate for you.

Uses of Vokanamet 50/1000 Tablet

Vokanamet 50/1000 Tablet is used to treat Type 2 diabetes mellitus. The detailed uses of Vokanamet 50/1000 Tablet are as follows: 

  • Type 2 Diabetes Mellitus: Vokanamet 50/1000 Tablet helps lower daily blood sugar levels in adults whose glucose levels remain high despite dietary changes and physical exercise.
  • Reduction of Cardiovascular Risk: In adults who have both type 2 diabetes and established heart disease, this medication helps lower the risk of major adverse heart events, such as heart attacks or strokes.

Key Benefits

This medicine provides meaningful daily benefits that help you manage your health more comfortably:

  • Stable blood sugar levels: By preventing sharp spikes in glucose after eating, it helps you maintain more consistent energy levels throughout the day and reduces the fatigue caused by high blood sugar.
  • Heart and kidney protection: Controlling your blood sugar levels reduces chronic strain on your blood vessels, helping to preserve your long-term heart and kidney health.
  • Simplified daily routine: Because it combines two complementary active components into a single tablet, it reduces the number of pills you need to take each day, making it easier to stay on track with your treatment.

Directions for Use

  • Vokanamet 50/1000 Tablet should be taken with meals.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Vokanamet 50/1000 Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Vokanamet 50/1000 Tablet Works

Vokanamet 50/1000 Tablet contains metformin and canagliflozin, which work together in different ways to help control blood sugar levels. Metformin helps your body respond better to insulin, allowing your cells to use glucose (sugar) more effectively. It also reduces the amount of glucose produced by your liver and slows the absorption of glucose from food into your bloodstream. Canagliflozin works through your kidneys by blocking a protein called sodium-glucose co-transporter 2 (SGLT2), which normally reabsorbs glucose back into the body. This allows excess glucose to be removed from your body through your urine, helping lower blood sugar levels.
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Alcohol

Unsafe

It is advised to avoid alcohol intake since it may worsen the side effects like lactic acidosis and increase the risk of developing low blood sugar levels.

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Pregnancy

Caution

Canagliflozin in Vokanamet 50/1000 Tablet is not recommended during pregnancy. Your doctor may suggest other medications to control your blood sugar levels. Please consult your doctor before starting Vokanamet 50/1000 Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Vokanamet 50/1000 Tablet may be unsafe to use during breastfeeding since it is excreted into the breast milk. Please seek medical advice for further information.

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Driving

Caution

Your driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience blurred vision, dizziness or drowsiness due to extremely low or high blood sugar.

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Liver

Caution

Let your doctor know if you have any history of liver diseases or hepatic impairment when prescribed Vokanamet 50/1000 Tablet .

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Kidney

Unsafe

Vokanamet 50/1000 Tablet is contraindicated in patients with renal impairment/kidney diseases. Let your doctor know if you have any history of kidney diseases when you are prescribed Vokanamet 50/1000 Tablet .

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Children

Unsafe

Vokanamet 50/1000 Tablet is not recommended for people younger than 18 years of age.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems before taking Vokanamet 50/1000 Tablet .

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Geriatrics

Consult your doctor

This medicine is not safe for use in elderly patients due to its serious side effects.

What if I have taken an overdose of Vokanamet 50/1000 Tablet

If you suspect an overdose, seek immediate emergency medical attention right away. An overdose can cause severe low blood sugar or lactic acidosis, both of which require urgent clinical care.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water throughout the day. This medicine increases urination, which can raise the risk of dehydration, especially in hot weather or during intense physical activity.
  • Eat a structured diet: Focus on a balanced meal plan rich in fiber, whole grains, and lean proteins, while avoiding foods high in simple sugars and processed carbohydrates.
  • Maintain daily foot care: Inspect your feet every day for cuts, redness, sores, or swelling, and report any changes to your doctor immediately.
  • Prioritise personal hygiene: Practice careful genital hygiene to minimise the risk of developing yeast or urinary tract infections, which are more common due to the increased sugar in your urine.
  • Monitor blood glucose: Keep a regular log of your blood sugar levels as advised by your healthcare team to ensure you remain within your target range.
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How Soon It Starts Working

The time required for Vokanamet 50/1000 Tablet to start to work: Vokanamet 50/1000 Tablet starts to show its action within 1 to 2 hour of administration. The time for which the effects of Vokanamet 50/1000 Tablet last: Vokanamet 50/1000 Tablet effect lasts for 24 hours.

What if you forget to take Vokanamet 50/1000 Tablet

If you miss a dose, take it with food as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Vokanamet 50/1000 Tablet at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check the medicine before use: Do not take the tablet if the packaging is damaged or if the tablet is cracked, broken, or discoloured.
  • Before surgery or dental procedures: Tell your doctor, surgeon, or dentist that you are taking Vokanamet 50/1000 Tablet well in advance, as your treatment may need to be stopped temporarily before certain procedures.
  • Alcohol: Limit or avoid alcohol while taking Vokanamet 50/1000 Tablet , as it may increase the risk of a build-up of lactic acid in the blood (lactic acidosis).
  • Watch for low blood sugar: Carry a fast-acting source of sugar, such as glucose tablets, fruit juice, or regular (non-diet) soft drinks, especially if you are also taking other diabetes medicines that can lower blood sugar.
  • Regular monitoring: Attend all follow-up appointments and blood tests. Your doctor may monitor your blood sugar, kidney function, and liver function during treatment.

verifiedApollotooltip

The following medicines may interact with Vokanamet 50/1000 Tablet and require closer monitoring or dose adjustments:

  • Water pills (diuretics): Taking these with Vokanamet 50/1000 Tablet can significantly increase your risk of dehydration and dangerously low blood pressure.
  • Insulin or sulfonylureas: Combining these blood sugar-lowering medicines with Vokanamet 50/1000 Tablet can increase your risk of low blood sugar, which may require your doctor to adjust your doses.
  • Blood pressure medications (specifically ACE inhibitors or ARBs): May increase the risk of kidney function changes when taken together.
  • Iodinated contrast media (used in medical imaging scans): Can temporarily impair kidney function and increase the risk of lactic acidosis; you must stop taking Vokanamet 50/1000 Tablet before and for a short period after these scans as directed by your physician.

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verifiedApollotooltip

Certain foods or drinks may affect the safety or tolerability of Vokanamet 50/1000 Tablet . Important interactions include:

  • Alcohol: Avoid or strictly limit alcohol, as it increases the risk of lactic acidosis and can cause unpredictable fluctuations in your blood sugar levels.

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Vokanamet 50/1000 Tablet is used to treat type 2 diabetes mellitus with a proper diet and exercise. It also lowers the risk of heart attack, stroke or heart failure in type 2 diabetic patients with heart diseases.
Vokanamet 50/1000 Tablet contains two antidiabetic medicines: Metformin and Canagliflozin. These drugs lower the blood sugar levels in type 2 diabetes mellitus by eliminating excess sugars through urine and increasing insulin activity. Vokanamet 50/1000 Tablet also reduces the risk of death due to heart attack, stroke and end-stage kidney disease in type 2 diabetic patients with heart/kidney diseases.
Vokanamet 50/1000 Tablet may cause low blood sugar levels (hypoglycaemia) and can make you hungry, dizzy, irritable, confused, anxious, or shaky. Hence, it is advised to take Vokanamet 50/1000 Tablet with a meal. To immediately treat hypoglycaemia, it is advised to eat or drink fast-acting sugar sources like fruit juices, hard candy, raisins or non-diet soda. Consult your doctor immediately.
Your doctor may advise Vokanamet 50/1000 Tablet with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to achieve the controlled blood sugar levels while using Vokanamet 50/1000 Tablet with or without other antidiabetic drugs.
Vokanamet 50/1000 Tablet should be used with caution in heart, kidney or liver diseases, breathing problems, blood disorders, dehydration, alcohol use, foot ulcers, nerve damage, low blood pressure and yeast infection of genitals. Vokanamet 50/1000 Tablet is contraindicated in patients with renal impairment and diabetic ketoacidosis.
While using Vokanamet 50/1000 Tablet , if you experience vomiting, stomach/abdominal pain, muscle cramps, sick feeling, severe tiredness, difficulty in breathing or reduced body temperature and heartbeat, it is important to seek immediate medical help since these are the symptoms of lactic acidosis. Lactic acidosis is a rare but a serious complication caused due to accumulation of metformin. It is a medical emergency and needs immediate treatment. Please consult your doctor for further information.
It is not recommended to use Vokanamet 50/1000 Tablet along with water pills/diuretics. Simultaneous use of Vokanamet 50/1000 Tablet and water pills causes dehydration and may increase the risk of lactic acidosis.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
Yes, long term use of metformin in Vokanamet 50/1000 Tablet may cause a decrease in the amount of vitamin B12 in your blood, especially if you have had low vitamin B12 blood levels before. Consult your doctor for further advice.
No, this medication is generally not recommended during pregnancy, particularly in the second and third trimesters, or while breastfeeding. Talk to your doctor to discuss safer, alternative methods for managing your blood sugar during this time.
This medicine works by removing excess sugar from your body through your urine. Because yeast thrives on sugar, the increased sugar content in your urinary tract can lead to yeast infections. Maintaining good daily hygiene and staying hydrated can help reduce this risk. Talk to your doctor if you experience symptoms.
If you feel shaky, sweaty, dizzy, or have a fast heartbeat, consume a fast-acting source of sugar immediately, such as three to four glucose tablets or half a cup of fruit juice. Rest and monitor your symptoms. Talk to your doctor if these episodes happen frequently.
Yes, your doctor will request routine laboratory tests to monitor your kidney function, liver health, and haemoglobin A1c levels to ensure the medication is working safely and effectively. Talk to your doctor about your regular testing schedule.
No, you should not stop taking this medicine without consulting your healthcare provider. Your blood sugar is controlled because the medicine is actively working; stopping it abruptly can cause your blood sugar levels to rise again. Talk to your doctor before making any changes.
While this medicine is not a weight-loss product, some patients may notice a modest reduction in weight as a side effect because the body is excreting calories in the form of sugar through the urine. Talk to your doctor for a complete, healthy weight-management plan.
This medication causes your body to lose more fluids through your urine as it filters out excess sugar. If you do not drink enough water, this increased urination can lead to dehydration and low blood pressure. Talk to your doctor if you have difficulty maintaining your fluid intake.
No, you will typically need to temporarily stop taking this medication before and for at least 48 hours after any imaging scan that uses contrast dye, as the combination can place extra stress on your kidneys. Talk to your doctor for precise instructions before your procedure.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

INDIA

Manufacturer/Marketer address

Corporate Communications, Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060
Other Info - VOK0003
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