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compositionComposition:CEFTAZIDIME-250MG
prescription
Prescription Medicine
info
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Volcef-250 Injection 1's is used to treat bacterial infections. It contains Ceftazidime which works by damaging the bacterial cell wall and killing bacteria. In some cases, this medicine may cause side effects such as redness or swelling at the site of injection or diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFTAZIDIME-250MG

Manufacturer/Marketer :

Biochemix Health Care Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Volcef-250 Injection 1's

Volcef-250 Injection 1's is a prescription antibiotic injection used to treat serious bacterial infections throughout the body. It is commonly prescribed to treat infections in the lungs, skin, stomach, and urinary tract. This medicine is typically injected into a vein or muscle under medical supervision.

Because this medicine is given as an injection, you do not need to worry about taking it with or without food. However, it is vital to receive this treatment at consistent times as directed by your doctor to keep a steady level of the medicine in your body. To support your recovery, drink plenty of fluids and get adequate rest while receiving this treatment.

Most people tolerate this injection well, but some may experience mild side effects like swelling at the injection site or stomach upset. If you develop severe watery diarrhea, a skin rash, or difficulty breathing, you must seek medical help immediately. Always consult your doctor if you experience any unusual symptoms during your treatment.

Do not take this if you have had a severe allergic reaction to similar antibiotics in the past. Before starting this medicine, tell your doctor if you have kidney disease or a history of bowel inflammation.

This medicine can interact with certain other treatments, such as strong water pills, which can increase the risk of kidney strain. If you are pregnant, breastfeeding, or managing health conditions as an older adult, consult your healthcare provider to ensure this treatment is safe for you.

Uses of Volcef-250 Injection 1's

Your doctor may prescribe this medicine to treat several conditions, including:

  • Severe lung infections (pneumonia): Stops the growth of bacteria deep in the lungs to help you breathe easier.
  • Complicated urinary tract infections: Clears stubborn bacterial infections in the kidneys and bladder.
  • Skin and soft tissue infections: Destroys bacteria causing deep, painful infections in the skin layers.
  • Intra-abdominal infections: Treats serious bacterial infections inside the stomach cavity and surrounding organs.
  • Meningitis: Fights dangerous bacterial infections affecting the membranes around the brain and spinal cord.
  • Bloodstream infections: Targets and eliminates bacteria that have entered the blood, preventing widespread organ damage.
  • Pseudomonas infection: Helps treat serious infections caused by Pseudomonas aeruginosa, a type of bacteria that can be difficult to treat

Key Benefits

Volcef-250 Injection 1's provides the following benefits when used as prescribed:

  • Fast-Acting Infection Relief: By being injected directly into the body, Volcef-250 Injection 1's provides fast-acting relief because it bypasses the digestive system and enters the bloodstream immediately. This rapid action helps stop severe, fast-spreading bacterial infections from causing further damage to vital organs.
  • Targets Resistant Bacteria: It is highly effective against hard-to-treat bacteria that are resistant to other standard antibiotics.
  • Supports Faster Recovery: Patients typically experience a steady reduction in fever, pain, and other infection symptoms, helping them recover their strength and return to daily activities faster.
     
Side effects of Volcef-250 Injection
  • Eosinophil levels can be lowered by eating fruits and vegetables, avoiding smoking, and consuming alcohol in moderation.
  • Several foods, such as ginger, garlic, pepper, turmeric, and honey, might boost immunity.
  • Avoid dairy products, including cheese, yoghurt, and milk.
  • Drink water and keep yourself hydrated.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Tell your healthcare provider about symptoms you are experiencing to explore treatment options.
  • Talk to your doctor about the medication history for finding the root cause and get change in dose or medications if required.
  • Identify the allergen causing the reaction and avoid further exposure to it.
  • Use medications as instructed by your doctor.
  • Regularly monitor heart rate, blood pressure, and breathing.
  • Wear comfortable clothes to aid breathing.
  • People with severe allergies should wear a medical alert bracelet to inform healthcare providers about their sensitivities.
  • Consult a healthcare professional to identify specific allergens through allergy testing.
  • Develop a personalized plan with your doctor to manage your allergies, including avoiding triggers and proper medication use.
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.
  • Eat a balanced diet rich in fruits, vegetables, whole grains, lean protein, and healthy fats.
  • Boost fiber, fruits, vegetables, omega-3 fatty acids, and vitamin K-rich foods.
  • Limit red meat, processed foods, sugary drinks, and excessive alcohol.
  • Exercise regularly with moderate-intensity activities for healthy blood flow.
  • Stay hydrated by drinking plenty of water.
  • Quit smoking to reduce blood clot risk.
  • Practice stress-reducing techniques like yoga or meditation.
  • Maintain a healthy weight to lower cardiovascular risk.
  • Always seek guidance from a healthcare professional before implementing major changes to your diet or lifestyle.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Volcef-250 Injection 1's will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Volcef-250 Injection 1's Works

Ceftazidime belongs to a class of antibiotics that target the protective outer layer of bacteria. Bacteria must continuously build and repair their cell walls to survive and multiply in the human body. This medicine works by blocking the specific proteins that bacteria use to build these protective walls. Without a strong cell wall, the bacteria cannot withstand internal pressure, causing them to rupture and die. Because human cells do not have cell walls, this process specifically targets and destroys the invading bacteria without harming your own cells.
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Alcohol

Caution

The interaction of Volcef-250 Injection 1's with alcohol is unknown. Please consult a doctor before consuming alcohol while using Volcef-250 Injection 1's.

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Pregnancy

Caution

Volcef-250 Injection 1's is a category B pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Volcef-250 Injection 1's may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Volcef-250 Injection 1's may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Volcef-250 Injection 1's.

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Liver

Caution

Take Volcef-250 Injection 1's with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Volcef-250 Injection 1's with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Volcef-250 Injection 1's should be used in children only in doses as prescribed by a doctor.

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Heart

Caution

Volcef-250 Injection 1's should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving Volcef-250 Injection 1's.

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Geriatrics

Caution

Volcef-250 Injection 1's should be administered with caution to elderly patients due to an increased risk of side effects. Please consult your doctor before receiving Volcef-250 Injection 1's.

What if I have taken an overdose of Volcef-250 Injection 1's

If you suspect an overdose, or if you experience severe symptoms like seizures or confusion after receiving an injection, seek emergency medical care.

Diet & Lifestyle Advise

  • Probiotic and Gut Health: Take a high-quality probiotic or eat fermented foods like yogurt (separated by a few hours from your injection) to help restore healthy gut bacteria.
  • Stay Well Hydrated: Stay well-hydrated by drinking plenty of water to help your kidneys process and clear the medicine efficiently.
  • Get Adequate Rest: Get plenty of rest to support your immune system while your body fights off the infection.
  • Avoid Alcohol: Avoid drinking alcohol, as it can stress your liver and cause dehydration during your recovery.
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How Soon It Starts Working

The time required for Volcef-250 Injection 1's to start to work: Volcef-250 Injection 1's ideally shows its action within 1 hour after administration. The time for which the effects of Volcef-250 Injection 1's last: The effect of Volcef-250 Injection 1's lasts for 8 to 12 hours.

What if you forget to take Volcef-250 Injection 1's

If you miss an injection appointment or miss a dose at home, contact your doctor or healthcare provider immediately for instructions. Do not inject a double dose to make up for a missed one.

Storage

• Store dry powder vials at room temperature, between 20°C to 25°C (68°F to 77°F), away from direct light and heat.

Drug Warnings

  • Inspect Vial: Always inspect the vial before use and discard it if you see floating particles, cloudiness, or unusual discoloration.
  • Injection Site Rotation: Rotate your injection sites regularly to reduce the risk of pain, swelling, or tissue damage at the injection area.
  • Sterile Needle Use: Use a new, sterile needle and syringe for every single injection to prevent serious blood infections.
  • Finish Course: Complete the entire prescribed course of treatment, even if you feel completely better, to prevent the infection from returning.
  • Kidney Warning: Inform your doctor immediately if you have kidney disease, as your dose may need to be adjusted to prevent side effects.

Drug-Drug Interactions

verifiedApollotooltip
  • Strong water pills (like furosemide): May increase the risk of kidney damage when used together.
  • Certain other antibiotics (like aminoglycosides): Can increase stress and potential damage to the kidneys.
  • Oral typhoid vaccine: This antibiotic may decrease the effectiveness of live bacterial vaccines.
CeftazidimeBCG vaccine
Critical
CeftazidimeCholera vaccines
Severe

Drug-Drug Interactions

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CeftazidimeBCG vaccine
Critical
How does the drug interact with Volcef-250 Injection:
When BCG vaccine is used with Volcef-250 Injection, its effectiveness may be reduced.

How to manage the interaction:
Taking Volcef-250 Injection with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.
CeftazidimeCholera vaccines
Severe
How does the drug interact with Volcef-250 Injection:
Taking the cholera vaccine after or along with Volcef-250 Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although there is a possible interaction between Volcef-250 Injection and Cholera vaccines, you can take these medicines together if prescribed by your doctor. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. Do not stop using any medications without consulting a doctor.
CeftazidimeCholera, live attenuated
Severe
How does the drug interact with Volcef-250 Injection:
Taking the cholera vaccine after or along with Volcef-250 Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Volcef-250 Injection with Cholera, live attenuated can possibly result in an interaction, but it can be taken if your doctor has advised it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Volcef-250 Injection 1's when used as directed.     
 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Volcef-250 Injection 1's contains Ceftazidime, an antibiotic that works by damaging the bacterial cell wall (protective covering) that is necessary for their survival. Thereby, kills bacteria.
Volcef-250 Injection 1's may be used to treat meningitis (inflammation of membranes covering the brain and spinal cord) caused by bacterial infection. Volcef-250 Injection 1's is an antibiotic that kills bacteria and prevents the spread of infection.
Volcef-250 Injection 1's may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, avoid taking Volcef-250 Injection 1's and consult a doctor immediately.
You are not recommended to take Volcef-250 Injection 1's with furosemide as co-administration of these two medicines may increase the risk of kidney problems, especially in patients with kidney impairment and also when Volcef-250 Injection 1's is given in high doses. However, please consult your doctor before taking Volcef-250 Injection 1's with other medicines.
Volcef-250 Injection 1's is not used to treat viral infections. Volcef-250 Injection 1's is an antibiotic that is used to treat only bacterial infections.
You are not recommended to stop taking Volcef-250 Injection 1's without consulting your doctor as it may worsen the infection or cause recurring symptoms. Therefore, take Volcef-250 Injection 1's for as long as your doctor has prescribed it and if you experience any difficulty while taking Volcef-250 Injection 1's, please consult your doctor.
Volcef-250 Injection 1's belongs to a class of antibiotics used to treat several bacterial infections.
Volcef-250 Injection 1's contains Ceftazidime, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria.
Common side effects of Volcef-250 Injection 1's may include redness and swelling along with a vein, a red raised skin rash that may be itchy, burning, painful, inflammation, or swelling at the site of injection, or diarrhoea. Most of these side effects of Volcef-250 Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
It is injected directly into a vein or deep into a muscle by a healthcare professional, or by yourself at home after proper training. Talk to your doctor.
Yes, if your healthcare provider decides it is appropriate and trains you thoroughly on safe injection techniques. Talk to your doctor.
Mild redness and pain can happen, but if the swelling, redness, or pain worsens or becomes hot to the touch, contact your healthcare provider. Talk to your doctor.
It is best to avoid alcohol while recovering from a serious infection, as it can dehydrate your body and affect your recovery. Talk to your doctor.
This medicine should only be used during pregnancy if clearly needed and prescribed by your healthcare provider. Talk to your doctor.
Contact your healthcare provider immediately to get advice on when to receive your next dose. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.275 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Ceftazidime Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Drugs H. Ceftazidime Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2025 [Accessed on 30 Sep 2025]Check here
  4. FORTAZ® (ceftazidime for injection) USP [Internet]. Accessdata.fda.gov. 2025 [Accessed on 30 Sep 2025]Check here
  5. Ceftazidime 1g Powder for Solution for Injection or Infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 30 Sep 2025]Check here
  6. Ceftazidime 1g Powder for Solution for Injection or Infusion - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 30 Sep 2025]Check here
  7. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Ceftazidime. [Accessed on 15th July 2022]Check here

Country of origin

India

Manufacturer/Marketer address

Dsco 54, Tau Devilal Market, Near Kanhaiya Sahib Chowk, Yamunanagar - 135001, Haryana, India
Other Info - VOL0461
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