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Composition :

VORICONAZOLE-200MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Vorihope 200 mg Injection

Vorihope 200 mg Injection is used to treat a broad range of fungal infections. A fungal infection is caused when a fungus invades and affects any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area and blood.

Vorihope 200 mg Injection contains ‘Voriconazole’ that kills or prevents fungi or yeast by inhibiting an enzyme in fungi, which interferes with the fungal cell membrane's formation.

In some cases, you may experience certain common side effects, such as injection site reactions, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills. Talk to your doctor if you experience these side effects persistently.

Before taking Vorihope 200 mg Injection, let your doctor know about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Vorihope 200 mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Uses of Vorihope 200 mg Injection

Vorihope 200 mg Injection is used in the treatment of Fungal infections. The detailed uses of Vorihope 200 mg Injection are as follows:

  • Treat invasive aspergillosis: Vorihope 200 mg Injection is a first-line antifungal therapy for serious infections caused by Aspergillus species, especially in immunocompromised patients such as those undergoing chemotherapy or organ transplantation.
  • Manage candidemia and deep tissue Candida infections: Vorihope 200 mg Injection is used to treat bloodstream infections and other severe Candida infections in patients who are not neutropenic, offering broad-spectrum antifungal coverage.
  • Treat esophageal candidiasis: Vorihope 200 mg Injection helps eliminate Candida infections in the esophagus, especially in patients who cannot tolerate oral antifungals.
  • Combat rare and resistant fungal infections: Vorihope 200 mg Injection is effective against Scedosporium apiospermum and Fusarium species, including Fusarium solani, in patients who are intolerant of or refractory to other antifungal therapies.

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Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Vorihope 200 mg Injection will be administered by a healthcare professional.
  • Do not self-administer.

Medicinal Benefits

  • Vorihope 200 mg Injection is an antifungal medicine containing Voriconazole, used to treat a broad range of infections caused due to fungi and yeast.
  • It treats various fungal infections like invasive aspergillosis (fungal infection in the lungs), esophageal candidiasis (white patching in the mouth and throat) and candidemia (a fungal infection in the blood).
  • It is also used to treat certain fungal infections when other medications do not work for certain patients.
  • It works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for their normal fat metabolism, thereby interfering with the formation of the fungal cell membrane.
  • It also effectively treats CNS fungal infections transmitted by epidural injection of contaminated steroids.
  • On the other hand, it can prevent fungal infections in people undergoing bone marrow transplants.

How Vorihope 200 mg Injection Works

Vorihope 200 mg Injection contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Storage

• Store in a cool and dry place away from sunlight.• Keep Vorihope 200 mg Injection out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Vorihope 200 mg Injection
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat more potassium-rich foods, like bananas, leafy greens, sweet potatoes, avocados, and nuts/seeds.
  • Choose potassium-fortified foods such as orange juice and sports beverages.
  • Limit potassium-depleting foods like caffeine, processed foods, and sugary drinks.
  • Exercise regularly, like walking or yoga, to help maintain potassium balance.
  • Inform your doctor if hypokalemia doesn't improve or worsen despite treatment.

What if I have taken an overdose of Vorihope 200 mg Injection

As Vorihope 200 mg Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

  • Inform your doctor about your medical conditions, sensitivities, and medications you are using.
  • And also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding.
  • Women of childbearing potential should always use effective contraception during treatment.
  • Please inform your doctor if you are suffering from a heart problem like an irregular heartbeat, slow heart rate or abnormality in ECG (electrocardiogram), QT prolongation, or if you have hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption.
  • Vorihope 200 mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Vorihope 200 mg Injection:
Coadministration of Vorihope 200 mg Injection with Efavirenz can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Efavirenz can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Using Ticagrelor together with Vorihope 200 mg Injection can significantly increase the blood levels of Ticagrelor.

How to manage the interaction:
Taking Ticagrelor with Vorihope 200 mg Injection is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Coadministration of Sirolimus and Vorihope 200 mg Injection can increase blood levels and side effects of Vorihope 200 mg Injection.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Sirolimus is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Co-administration of Vorihope 200 mg Injection with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Vorihope 200 mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Using Cisapride together with Vorihope 200 mg Injection may significantly increase the blood levels and effects of cisapride.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Cisapride is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Using Sparfloxacin together with Vorihope 200 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Sparfloxacin is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Co-administration of Silodosin together with Vorihope 200 mg Injection, may significantly increase the blood levels and effects of Silodosin which may lead to side effects.

How to manage the interaction:
Taking Vorihope 200 mg Injection and Silodosin is not recommended, but it can be taken if prescribed by a doctor. If you experience dizziness, headache, heart palpitation-call a doctor right away. Do not stop using any medications without a doctor's advice.
VoriconazoleConivaptan
Critical
How does the drug interact with Vorihope 200 mg Injection:
Using Conivaptan together with Vorihope 200 mg Injection may significantly increase the blood levels and effects of conivaptan.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Conivaptan is not recommended, please consult your doctor before taking it. Call a doctor if you experience difficulty swallowing, trouble speaking, trouble controlling body movements. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Using alfuzosin together with Vorihope 200 mg Injection may significantly increase the blood levels and effects of alfuzosin.

How to manage the interaction:
Taking Vorihope 200 mg Injection with Alfuzosin is not recommended, please consult a doctor before taking it. Call a doctor if you experience dizziness, headache, nasal congestion, or heart palpitation. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vorihope 200 mg Injection:
Using ivabradine together with Vorihope 200 mg Injection may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Vorihope 200 mg Injection together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • In wet places such as changing rooms and gym showers, don’t walk barefoot to prevent fungal infections.
  • Do not scratch the affected skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.
  • It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS
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Alcohol

Consult your doctor

It is not known if alcohol affects Vorihope 200 mg Injection. Please consult your doctor.

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Pregnancy

Consult your doctor

Vorihope 200 mg Injection is generally not recommended in pregnancy. Your doctor may prescribe this medicine if the benefit to the mother outweighs the potential risk to the fetus.

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Breast Feeding

Consult your doctor

If you are breastfeeding, please inform your doctor. It is not known if Vorihope 200 mg Injection passes into breastmilk. Your doctor may advise you to stop breastfeeding before starting the treatment with Vorihope 200 mg Injection.

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Driving

Unsafe

Vorihope 200 mg Injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

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Liver

Consult your doctor

Inform your doctor if you have liver problems before receiving Vorihope 200 mg Injection.

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Kidney

Consult your doctor

Inform your doctor if you have kidney problems before receiving Vorihope 200 mg Injection.

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Children

Consult your doctor

Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Heart

Vorihope 200 mg Injection may disrupt heart rhythm, so patients with heart conditions must consult their doctor before use. Careful monitoring is crucial to avoid serious cardiac side effects.

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Geriatrics

Caution

Geriatric patients may receive Vorihope 200 mg Injection, but only with close medical supervision. Older adults are more prone to side effects like visual disturbances, liver issues, and heart rhythm changes, so dosage and monitoring must be carefully tailored.

FAQs

Vorihope 200 mg Injection is used to treat fungal infections.

Vorihope 200 mg Injection contains Voriconazole that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Vorihope 200 mg Injection can also prevent fungal infections in people undergoing bone marrow transplants.

Vorihope 200 mg Injection may not be suitable in patients with known hypersensitivity to any of the components present in Vorihope 200 mg Injection; or with a hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption.

You can take Vorihope 200 mg Injection with contraceptive pills. However, some studies show a chance of an increase in the body's hormonal levels when you take Vorihope 200 mg Injection with a combined pill. Seek your doctor's advice if any side effects occur.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person, as it can also spread the infection.

Vorihope 200 mg Injection can use women of childbearing potential; however, they must always use effective contraception during treatment.

Country of origin

India

Manufacturer/Marketer address

401, Lsc, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 In.
Other Info - VOR0107

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