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Composition :

VORICONAZOLE-200MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About VORAZE 200MG VIAL injection

VORAZE 200MG VIAL injection is used to treat a broad range of fungal infections. A fungal infection is caused when a fungus invades and affects any body part, including the mouth, throat, oesophagus, lungs, bladder, genital area and blood.

VORAZE 200MG VIAL injection contains ‘Voriconazole’ that kills or prevents fungi or yeast by inhibiting an enzyme in fungi which interferes with the fungal cell membrane's formation.

In some cases, you may experience certain common side effects, such as injection site reactions, headache, diarrhoea, vomiting, abdominal pain, chest pain, nausea, fever, insomnia, confusion, weakness, tingling sensation, sleepiness, dizziness, stomach upset, constipation, rashes, itchiness, red skin, back pain and chills. Talk to your doctor if you experience these side effects persistently.

Before taking VORAZE 200MG VIAL injection, let your doctor know about your medical condition, sensitivities, and medications. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. VORAZE 200MG VIAL injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Uses of VORAZE 200MG VIAL injection

VORAZE 200MG VIAL injection is used in the treatment of Fungal infections. The detailed uses of VORAZE 200MG VIAL injection are as follows:

  • Treat invasive aspergillosis: VORAZE 200MG VIAL injection is a first-line antifungal therapy for serious infections caused by Aspergillus species, especially in immunocompromised patients such as those undergoing chemotherapy or organ transplantation.
  • Manage candidemia and deep tissue Candida infections: VORAZE 200MG VIAL injection is used to treat bloodstream infections and other severe Candida infections in patients who are not neutropenic, offering broad-spectrum antifungal coverage.
  • Treat esophageal candidiasis: VORAZE 200MG VIAL injection helps eliminate Candida infections in the esophagus, especially in patients who cannot tolerate oral antifungals.
  • Combat rare and resistant fungal infections: VORAZE 200MG VIAL injection is effective against Scedosporium apiospermum and Fusarium species, including Fusarium solani, in patients who are intolerant of or refractory to other antifungal therapies.

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Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • VORAZE 200MG VIAL injection will be administered by a healthcare professional.
  • Do not self-administer.

Medicinal Benefits

  • VORAZE 200MG VIAL injection is an antifungal medicine containing Voriconazole, used to treat a broad range of infections caused due to fungi and yeast.
  • It treats various fungal infections like invasive aspergillosis (fungal infection in the lungs), esophageal candidiasis (white patching in the mouth and throat) and candidemia (a fungal infection in the blood).
  • It is also used to treat certain fungal infections when other medications do not work for certain patients.
  • It works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for their normal fat metabolism, thereby interfering with the formation of the fungal cell membrane.
  • It also effectively treats CNS fungal infections transmitted by epidural injection of contaminated steroids.
  • On the other hand, it can prevent fungal infections in people undergoing bone marrow transplants.

How VORAZE 200MG VIAL injection Works

VORAZE 200MG VIAL injection contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

Storage

• Store in a cool and dry place away from sunlight.• Keep VORAZE 200MG VIAL injection out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of VORAZE 200MG VIAL injection
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of VORAZE 200MG VIAL injection

As VORAZE 200MG VIAL injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

  • Inform your doctor about your medical conditions, sensitivities, and medications you are using.
  • And also, let your doctor know if you are pregnant, planning to become pregnant, or breastfeeding.
  • Women of childbearing potential should always use effective contraception during treatment.
  • Please inform your doctor if you are suffering from a heart problem like an irregular heartbeat, slow heart rate or abnormality in ECG (electrocardiogram), QT prolongation, or if you have hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption.
  • VORAZE 200MG VIAL injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

Drug-Drug Interactions

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VoriconazoleVoclosporin
Critical

Drug-Drug Interactions

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VoriconazoleVoclosporin
Critical
How does the drug interact with VORAZE 200MG VIAL injection:
Using Voclosporin together with VORAZE 200MG VIAL injection may significantly increase the blood levels of Voclosporin.

How to manage the interaction:
Taking VORAZE 200MG VIAL injection with Voclosporin is not recommended, please consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Coadministration of Methylergometrine with VORAZE 200MG VIAL injection may increase the blood level of Methylergometrine.

How to manage the interaction:
Although Methylergometrine with VORAZE 200MG VIAL injection can cause an interaction, they can be taken if prescribed by a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Co-administration of VORAZE 200MG VIAL injection with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with VORAZE 200MG VIAL injection together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Co-administration of Silodosin together with VORAZE 200MG VIAL injection, may significantly increase the blood levels and effects of Silodosin which may lead to side effects.

How to manage the interaction:
Taking VORAZE 200MG VIAL injection and Silodosin is not recommended, but it can be taken if prescribed by a doctor. If you experience dizziness, headache, heart palpitation-call a doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with VORAZE 200MG VIAL injection:
Using Nimodipine together with VORAZE 200MG VIAL injection may significantly increase the risk of serous side effects.

How to manage the interaction:
Taking Nimodipine with VORAZE 200MG VIAL injection is not recommended, as it may lead to an interaction, but it can be taken if prescribed by the doctor. However, if you experience symptoms such as irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Using ivabradine together with VORAZE 200MG VIAL injection may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with VORAZE 200MG VIAL injection together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Using VORAZE 200MG VIAL injection together with Carbamazepine may significantly reduce the blood levels of VORAZE 200MG VIAL injection.

How to manage the interaction:
Taking Carbamazepine with VORAZE 200MG VIAL injection is not recommended, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Coadministration of VORAZE 200MG VIAL injection with Efavirenz can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking VORAZE 200MG VIAL injection with Efavirenz can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Coadministration of Sirolimus and VORAZE 200MG VIAL injection can increase blood levels and side effects of VORAZE 200MG VIAL injection.

How to manage the interaction:
Taking VORAZE 200MG VIAL injection with Sirolimus is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
How does the drug interact with VORAZE 200MG VIAL injection:
Co-administration of Ranolazine together with VORAZE 200MG VIAL injection may significantly increase the blood levels and effects of Ranolazine.

How to manage the interaction:
Taking Ranolazine with VORAZE 200MG VIAL injection together can result in an interaction, but it can be taken if a doctor has advised it. Consult a doctor if you experience dizziness, or fast or pounding heartbeats. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • In wet places such as changing rooms and gym showers, don’t walk barefoot to prevent fungal infections.
  • Do not scratch the affected skin, as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.
  • It is advisable to follow a candida diet during fungal infections. This diet excludes sugar, gluten, certain dairy products, and alcohol. Switch to low-sugar fruits, non-starchy vegetables and gluten-free foods. A very-high sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS
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Alcohol

Consult your doctor

It is not known if alcohol affects VORAZE 200MG VIAL injection. Please consult your doctor.

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Pregnancy

Consult your doctor

VORAZE 200MG VIAL injection is generally not recommended in pregnancy. Your doctor may prescribe this medicine if the benefit to the mother outweighs the potential risk to the fetus.

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Breast Feeding

Consult your doctor

If you are breastfeeding, please inform your doctor. It is not known if VORAZE 200MG VIAL injection passes into breastmilk. Your doctor may advise you to stop breastfeeding before starting the treatment with VORAZE 200MG VIAL injection.

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Driving

Unsafe

VORAZE 200MG VIAL injection may affect your ability to drive or operate machinery; thus, avoid driving or using machinery.

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Liver

Consult your doctor

Inform your doctor if you have liver problems before receiving VORAZE 200MG VIAL injection.

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Kidney

Consult your doctor

Inform your doctor if you have kidney problems before receiving VORAZE 200MG VIAL injection.

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Children

Consult your doctor

Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Heart

VORAZE 200MG VIAL injection may disrupt heart rhythm, so patients with heart conditions must consult their doctor before use. Careful monitoring is crucial to avoid serious cardiac side effects.

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Geriatrics

Caution

Geriatric patients may receive VORAZE 200MG VIAL injection, but only with close medical supervision. Older adults are more prone to side effects like visual disturbances, liver issues, and heart rhythm changes, so dosage and monitoring must be carefully tailored.

FAQs

VORAZE 200MG VIAL injection is used to treat fungal infections.

VORAZE 200MG VIAL injection contains Voriconazole that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimized.

VORAZE 200MG VIAL injection can also prevent fungal infections in people undergoing bone marrow transplants.

VORAZE 200MG VIAL injection may not be suitable in patients with known hypersensitivity to any of the components present in VORAZE 200MG VIAL injection; or with a hereditary intolerance for galactose, Lapp lactase deficiency, or glucose-galactose malabsorption.

You can take VORAZE 200MG VIAL injection with contraceptive pills. However, some studies show a chance of an increase in the body's hormonal levels when you take VORAZE 200MG VIAL injection with a combined pill. Seek your doctor's advice if any side effects occur.

Yes, fungal infection is a contagious skin condition that spreads from one person to another through direct skin-to-skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person, as it can also spread the infection.

VORAZE 200MG VIAL injection can use women of childbearing potential; however, they must always use effective contraception during treatment.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - VOR0010

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