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  1. Home
  2. Medicine

  3. VORIZOL 50MG TABLET

Prescription drug
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VORIZOL 50MG TABLET, Pack of 1 TABLET
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Composition :

VORICONAZOLE-50MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About VORIZOL 50MG TABLET

VORIZOL 50MG TABLET is used to treat a broad range of infections caused by fungi and yeast. A fungal infection is caused when a fungus invades and affects any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area and blood.

VORIZOL 50MG TABLET contains ‘Voriconazole’ that kills or prevents fungi or yeast by inhibiting an enzyme in fungi, which interferes with the fungal cell membrane's formation.

In some cases, you may experience common side effects such as vomiting, headache, nausea, abnormal liver function tests, rash, slow heart rate, and altered vision. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Do not take VORIZOL 50MG TABLET if you have had an allergic reaction to VORIZOL 50MG TABLET or any of its ingredients. VORIZOL 50MG TABLET is associated with liver toxicity, including fatalities in patients with other serious underlying diseases. VORIZOL 50MG TABLET is a pregnancy category D drug, so it should not be taken by breastfeeding or pregnant women. Antacid should be taken at 2 hours after taking VORIZOL 50MG TABLET.

Uses of VORIZOL 50MG TABLET

VORIZOL 50MG TABLET is used to treat fungal infections. The detailed uses of VORIZOL 50MG TABLET are as follows:

  • Treat serious fungal infections: VORIZOL 50MG TABLET is primarily used for invasive fungal infections such as aspergillosis, candidemia, and infections caused by Scedosporium apiospermum and Fusarium spp., especially in immunocompromised patients.
  • Manage esophageal candidiasis: VORIZOL 50MG TABLET is effective in treating esophageal yeast infections, helping reduce inflammation and discomfort caused by Candida overgrowth.
  • Control fluconazole-resistant fungal strains: VORIZOL 50MG TABLET is useful against certain fungal organisms that are resistant to other antifungals like fluconazole, due to its strong inhibition of fungal cell membrane synthesis.

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Directions for Use

  • VORIZOL 50MG TABLET can be taken at least one hour before, or one hour after a meal.
  • Generally, VORIZOL 50MG TABLET is taken twice every day for the best results or as advised by a doctor.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • VORIZOL 50MG TABLET belongs to the class of medicines known as 'antifungal', containing Voriconazole, used to treat a broad range of infections caused by fungi and yeast.
  •  It treats various fungal infections like invasive aspergillosis (fungal infection in the lungs), oesophagal candidiasis (white patching in the mouth and throat) and candidemia (a fungal infection in the blood).
  • It is also used to treat certain fungal infections when other medications do not work for certain patients. 
  • It works by killing or preventing fungi or yeast by inhibiting an enzyme in fungi responsible for its normal fat metabolism, interfering with the fungal cell membrane's formation.

How VORIZOL 50MG TABLET Works

VORIZOL 50MG TABLET contains 'Voriconazole' that kills or prevents fungus by inhibiting an enzyme in fungi responsible for its normal fat metabolism, thereby interfering with the fungal cell membrane formation. As a result, fungal cells get killed, or their growth is minimised.

Storage

• Store in a cool and dry place away from sunlight.• Keep VORIZOL 50MG TABLET out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Vorizol 50mg Tablet
  • Your doctor may recommend regular liver function tests (LFT) to monitor liver enzyme levels.
  • To support your liver, eat a healthy diet with lots of fruits, vegetables, lean proteins, and healthy fats.
  • Avoid eating processed meats, sugary foods, and unhealthy fats.
  • Limit your alcohol consumption, since too much can worsen liver function and contribute to high levels of Alkaline Phosphatase (ALP).
  • Stay active with regular exercise, drink plenty of water, and try to avoid harmful chemicals that can damage your liver.
  • Quit smoking to lower the risk of elevated ALP levels.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Eat more potassium-rich foods, like bananas, leafy greens, sweet potatoes, avocados, and nuts/seeds.
  • Choose potassium-fortified foods such as orange juice and sports beverages.
  • Limit potassium-depleting foods like caffeine, processed foods, and sugary drinks.
  • Exercise regularly, like walking or yoga, to help maintain potassium balance.
  • Inform your doctor if hypokalemia doesn't improve or worsen despite treatment.

What if I have taken an overdose of VORIZOL 50MG TABLET

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include widened pupils, sensitivity to light, drooling, closed eyes, loss of balance while moving, shortness of breath, swollen stomach, extreme tiredness, seizures, and depression. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take VORIZOL 50MG TABLET if you have been allergic to any of its ingredients.
  • VORIZOL 50MG TABLET is associated with liver toxicity, including fatalities in patients with other serious underlying diseases.
  • If you are suffering from liver disease, the doctor will lower the dose, and a regular liver function test will be done.
  • VORIZOL 50MG TABLET is a pregnancy category D drug, so it should not be taken by breastfeeding and pregnant women.
  • If you are suffering from a heart problem like an irregular heartbeat, slow heart rate or abnormality in ECG (electrocardiogram), please inform your doctor before starting VORIZOL 50MG TABLET.
  • Exposure to sunlight should be avoided while taking VORIZOL 50MG TABLET as it makes you sensitive to the sun's UV rays, or use a high sun protection factor (SPF) while going out.
  • Antacid should be taken at 2 hours after taking VORIZOL 50MG TABLET.

Drug-Drug Interactions

verifiedApollotooltip
VoriconazoleEfavirenz
Critical
VoriconazoleTicagrelor
Critical

Drug-Drug Interactions

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VoriconazoleEfavirenz
Critical
How does the drug interact with Vorizol 50mg Tablet:
Coadministration of Vorizol 50mg Tablet with Efavirenz can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Efavirenz can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
VoriconazoleTicagrelor
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using Ticagrelor together with Vorizol 50mg Tablet can significantly increase the blood levels of Ticagrelor.

How to manage the interaction:
Taking Ticagrelor with Vorizol 50mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience vomiting, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
VoriconazoleSirolimus
Critical
How does the drug interact with Vorizol 50mg Tablet:
Coadministration of Sirolimus and Vorizol 50mg Tablet can increase blood levels and side effects of Vorizol 50mg Tablet.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Sirolimus is generally avoided as it can result in an interaction, please consult a doctor before taking it. Contact a doctor if you experience nausea, fever, abdominal pain, or yellowing of the skin or eyes. Do not stop using any medication without consulting a doctor.
VoriconazoleZiprasidone
Critical
How does the drug interact with Vorizol 50mg Tablet:
Co-administration of Vorizol 50mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Vorizol 50mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
VoriconazoleCisapride
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using Cisapride together with Vorizol 50mg Tablet may significantly increase the blood levels and effects of cisapride.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Cisapride is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, or fast or pounding heartbeats. Do not stop using any medications without talking to a doctor.
VoriconazoleSparfloxacin
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using Sparfloxacin together with Vorizol 50mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Sparfloxacin is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
VoriconazoleSilodosin
Critical
How does the drug interact with Vorizol 50mg Tablet:
Co-administration of Silodosin together with Vorizol 50mg Tablet, may significantly increase the blood levels and effects of Silodosin which may lead to side effects.

How to manage the interaction:
Taking Vorizol 50mg Tablet and Silodosin is not recommended, but it can be taken if prescribed by a doctor. If you experience dizziness, headache, heart palpitation-call a doctor right away. Do not stop using any medications without a doctor's advice.
VoriconazoleConivaptan
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using Conivaptan together with Vorizol 50mg Tablet may significantly increase the blood levels and effects of conivaptan.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Conivaptan is not recommended, please consult your doctor before taking it. Call a doctor if you experience difficulty swallowing, trouble speaking, trouble controlling body movements. Do not stop using any medications without talking to a doctor.
VoriconazoleAlfuzosin
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using alfuzosin together with Vorizol 50mg Tablet may significantly increase the blood levels and effects of alfuzosin.

How to manage the interaction:
Taking Vorizol 50mg Tablet with Alfuzosin is not recommended, please consult a doctor before taking it. Call a doctor if you experience dizziness, headache, nasal congestion, or heart palpitation. Do not stop using any medications without talking to a doctor.
VoriconazoleIvabradine
Critical
How does the drug interact with Vorizol 50mg Tablet:
Using ivabradine together with Vorizol 50mg Tablet may significantly increase the blood levels and effects of ivabradine.

How to manage the interaction:
Taking Ivabradine with Vorizol 50mg Tablet together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience dizziness, shortness of breath, rapid heartbeat. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Don't walk barefoot in wet places such as changing rooms and gym showers to prevent fungal infections.
  • Do not scratch the affected skin; it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bedsheets and towels regularly.
  • Avoid taking VORIZOL 50MG TABLET (oral form) with foods containing chocolate and caffeine, such as cocoa beans, tea, coffee, cola and energy drinks, as it may increase the adverse effects of caffeine.
  • Avoid alcohol intake with VORIZOL 50MG TABLET (oral form) as it may cause adverse effects and increase the risk of liver damage.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcohol and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods. A very high-sugar or high-carbohydrate diet may increase the count of Candida in some people.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

VORIZOL 50MG TABLET Substitute

Substitutes safety advice
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Alcohol

Unsafe

It is advisable to avoid or limit the intake of alcohol while you use VORIZOL 50MG TABLET.

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Pregnancy

Unsafe

It is unsafe to take VORIZOL 50MG TABLET during pregnancy since it may show harmful effects on the fetus as it is a pregnancy category D drug. There are chances of spontaneous abortions in women treated with VORIZOL 50MG TABLET in the first trimester. Consult your doctor for further advice.

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Breast Feeding

Consult your doctor

If you are breastfeeding, please consult your doctor before taking VORIZOL 50MG TABLET. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Unsafe

Do not drive or operate machines if you experience dizziness or sensitivity to sunlight after taking VORIZOL 50MG TABLET.

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Liver

Consult your doctor

Inform your doctor if you have liver problems before taking VORIZOL 50MG TABLET. Your doctor may adjust the dose if necessary based on your condition.

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Kidney

Consult your doctor

Inform your doctor if you have kidney problems before taking VORIZOL 50MG TABLET. Your doctor may adjust the dose if necessary based on your condition.

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Children

Consult your doctor

Please consult your doctor. Your doctor will prescribe VORIZOL 50MG TABLET based on your child's age, condition, and body weight.

FAQs

Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - VOR0022

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 21, 2025 | 11:46 AM IST

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Reference

  1. https://medlineplus.gov/druginfo/meds/a605022.html
  2. https://pubchem.ncbi.nlm.nih.gov/compound/Voriconazole
  3. https://www.medicines.org.uk/emc/files/pil.7981.pdf

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