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compositionComposition:VERAPAMIL-5MG
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Prescription Medicine
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Vpl 5 mg Injection 10 x 2 ml is used to treat abnormal heart rhythms (arrhythmias), such as irregular or rapid heart rates. It can also be used to treat high blood pressure (hypertension) and heart failure. It helps relax the blood vessels and decrease the workload on the heart. It also increases the blood and oxygen supply to the heart, normalising electrical impulses. These effects help reduce blood pressure and control the rate and rhythm of the heartbeat.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

VERAPAMIL-5MG

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Vpl 5 mg Injection 10 x 2 ml

Vpl 5 mg Injection 10 x 2 ml is a prescription medicine injected into a vein to treat certain types of fast or irregular heartbeats, such as supraventricular tachycardia. It is also used to control rapid heart rates in patients with atrial fibrillation or atrial flutter. This medicine is given under close medical supervision to help restore a normal, steady heart rhythm.

Because this medicine is given directly into a vein, it is typically used in a hospital or clinic setting for immediate relief during an episode of rapid heart rate. It is not a daily self-administered medicine, but rather a treatment used as needed under professional guidance. Maintaining a low-sodium diet and avoiding stimulants like caffeine can further support your heart health during recovery.

Some people may experience mild side effects, such as dizziness, low blood pressure, or a mild headache after receiving this injection. However, if you experience serious symptoms like extreme dizziness, fainting, shortness of breath, or a very slow heartbeat, tell your healthcare provider immediately.

Before receiving this medicine, it is important to tell your doctor if you have a history of heart failure, very low blood pressure, or specific heart rhythm disorders like sick sinus syndrome or second- or third-degree heart block (unless you have a working pacemaker). Do not take this if you are already taking certain other heart medicines, such as beta-blockers, through your veins.

This medicine can interact with other blood pressure drugs, alcohol, and certain antibiotics, which may cause your blood pressure to drop too low. Talk to your doctor if you are pregnant, planning to become pregnant, breastfeeding, or if the patient is an older adult, as you may be more sensitive to the effects of this medicine.

Uses of Vpl 5 mg Injection 10 x 2 ml

Vpl 5 mg Injection 10 x 2 ml is used in the treatment of abnormal heart rhythms (arrhythmias). The detailed uses of Vpl 5 mg Injection 10 x 2 ml are as follows:

  • Abnormal rapid heartbeats (Supraventricular tachycardia): It helps quickly slow down a racing heart and restore a normal heart rhythm.
  • Rapid heart rate in atrial fibrillation: It helps control and slow down the heart rate when the upper chambers of the heart beat too fast and irregularly.
  • Rapid heart rate in atrial flutter: It helps regulate the heartbeat by slowing the electrical signals passing through the heart.

Key Benefits

Vpl 5 mg Injection 10 x 2 ml helps restore a normal heart rhythm and control a fast heartbeat. The following are the benefits of this medication:

  • Helps slow down a dangerously fast heartbeat and relieve symptoms such as palpitations and chest discomfort.
  • Regulates the heart's electrical signals to maintain a steady and regular heart rhythm.
  • Improves blood flow by restoring a more effective heartbeat.
  • Reduces the workload on the heart, helping protect it from excessive strain.
  • Lowers the risk of complications associated with a persistently rapid heart rate.
Side effects of Vpl 5 mg Injection 10 x 2 ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Vpl 5 mg Injection 10 x 2 ml will be administered by a healthcare professional.
  • Do not self-administer.

How Vpl 5 mg Injection 10 x 2 ml Works

Vpl 5 mg Injection 10 x 2 ml works by relaxing the blood vessels and slowing down the electrical conduction system of the heart. It belongs to a class of medicines that block calcium from entering the muscle cells of your heart and blood vessels. Calcium is necessary for muscles to contract. By limiting calcium entry, this medicine relaxes the blood vessels, making it easier for blood to flow. At the same time, it slows the electrical impulses in the heart that cause it to beat too quickly. This dual action helps lower blood pressure and stabilises a racing heart.
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Alcohol

Unsafe

Do not consume alcohol while using Vpl 5 mg Injection 10 x 2 ml as it may worsen your condition.

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Pregnancy

Caution

Vpl 5 mg Injection 10 x 2 ml should be used with caution in pregnancy as it may harm your unborn baby. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Vpl 5 mg Injection 10 x 2 ml .

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Breast Feeding

Caution

Vpl 5 mg Injection 10 x 2 ml should not be used in nursing mothers unless necessary. So, inform your doctor if you are breastfeeding. Your doctor will weigh the benefits and potential risks before prescribing Vpl 5 mg Injection 10 x 2 ml .

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Driving

Caution

Vpl 5 mg Injection 10 x 2 ml may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy after taking this medicine.

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Liver

Caution

Inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml if you have a pre-existing or a history of liver disease/condition. Your doctor may adjust the dose depending on your current liver condition.

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Kidney

Caution

Inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml if you have a pre-existing or a history of kidney disease/condition. Your doctor may adjust the dose depending on your current medical condition.

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Children

Safe if prescribed

Please consult your paediatrician. Your child's doctor will weigh the benefits and potential risks before prescribing Vpl 5 mg Injection 10 x 2 ml .

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Heart

Caution

Vpl 5 mg Injection 10 x 2 ml may be used in heart patients, but only with caution due to its effects on heart rate and contractility. It can worsen heart failure or cause AV block, so close monitoring is essential.

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Geriatrics

Caution

Geriatric patients may receive Vpl 5 mg Injection 10 x 2 ml , but only with caution due to increased sensitivity to its heart effects. Medical supervision is essential to monitor blood pressure and heart rhythm closely.

What if I have taken an overdose of Vpl 5 mg Injection 10 x 2 ml

Because this medicine is given by medical professionals under close monitoring, an overdose is extremely rare. However, if you suspect an overdose or experience severe symptoms like extreme dizziness, confusion, or difficulty breathing, notify your medical team immediately or seek emergency medical attention.

Diet & Lifestyle Advise

  • Limit or avoid caffeine: Stimulants like caffeine in coffee, tea, soda, and energy drinks can trigger rapid heartbeats, reducing the effectiveness of your treatment.
  • Avoid alcohol: Drinking alcohol can lower your blood pressure further and interact poorly with your heart medication.
  • Eat a heart-healthy diet: Focus on low-sodium foods, fresh vegetables, and whole grains to help manage your blood pressure and overall cardiovascular health.
  • Manage stress levels: High stress can raise your heart rate. Practice calming techniques such as deep breathing, meditation, or gentle yoga as approved by your doctor.
health query

Have a query?

How Soon It Starts Working

  • The time required for Vpl 5 mg Injection 10 x 2 ml to start to work: Vpl 5 mg Injection 10 x 2 ml ideally shows its action within 3 to 5 minutes of IV administration.
  • The time for which the effects of Vpl 5 mg Injection 10 x 2 ml last: The effect of Vpl 5 mg Injection 10 x 2 ml lasts for 10 to 20 minutes after administration.

What if you forget to take Vpl 5 mg Injection 10 x 2 ml

Since this medicine is given by a healthcare provider in a hospital or clinic setting, it is highly unlikely that you will miss a dose. If you have concerns about your treatment schedule, talk to your doctor.

Storage

• Store the injection solution at room temperature, ideally between 15°C and 30°C (59°F and 86°F).

Drug Warnings

  • Inspect the solution: Before the injection is given, ensure the liquid is clear and colourless. Do not use if it is discoloured or contains floating particles.
  • Stay lying down: Remain lying down during and immediately after the injection to prevent a sudden drop in blood pressure and dizziness.
  • Continuous monitoring: Your doctor will monitor your blood pressure and heart rate closely during administration. Let them know immediately if you feel faint or short of breath.
  • Avoid sudden movements: Sit or stand up slowly after the procedure to avoid feeling dizzy or losing your balance.
  • Inform your care team: Always tell any doctor, dentist, or surgeon treating you that you have received Vpl 5 mg Injection 10 x 2 ml , especially before any medical procedures.

Drug-Drug Interactions

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  • Other blood pressure medicines (e.g., metoprolol): Combining Vpl 5 mg Injection 10 x 2 ml with other blood pressure treatments can cause your heart rate to slow down dangerously and lower your blood pressure too much.
  • Medicines used to treat heart failure (e.g., digoxin): This medicine can raise the levels of digoxin in your body, increasing the risk of side effects.
VerapamilArbutamine
Critical
VerapamilCisapride
Critical

Drug-Drug Interactions

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VerapamilArbutamine
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Taking Vpl 5 mg Injection 10 x 2 ml with Arbutamine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Arbutamine together is generally avoided as it can result in an interaction, it can be taken when a doctor has advised it. However, if you experience irregular heartbeat, chest tightness, blurred vision, or nausea. contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VerapamilCisapride
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Coadministration of cisapride together with Vpl 5 mg Injection 10 x 2 ml may significantly increase the blood levels of cisapride. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Cisapride is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment with cisapride.
VerapamilLomitapide
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Using lomitapide together with Vpl 5 mg Injection 10 x 2 ml may significantly increase the blood levels of lomitapide.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Lomitapide is generally avoided as it can possibly result in an interaction. Call a doctor if you experience diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, and yellowing of skin or eyes. Do not discontinue any medications without consulting a doctor.
VerapamilEliglustat
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
The metabolism of Eliglustat can be decreased when combined with Vpl 5 mg Injection 10 x 2 ml . This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VerapamilDofetilide
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Using dofetilide together with Vpl 5 mg Injection 10 x 2 ml may significantly increase the blood levels of dofetilide. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Dofetilide is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without first consulting a doctor.
VerapamilFlibanserin
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Using flibanserin together with Vpl 5 mg Injection 10 x 2 ml can significantly increase the blood levels of flibanserin.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Flibanserin is generally avoided as it can result in an interaction. Call a doctor immediately if you experience excessive drowsiness and decreases in blood pressure that can lead to dizziness, lightheadedness, fainting, and accidental injury, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VerapamilPimozide
Critical
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Using pimozide together with Vpl 5 mg Injection 10 x 2 ml can increase the blood levels and risk of developing irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Vpl 5 mg Injection 10 x 2 ml with Pimozide is generally avoided as it can cause an interaction. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
VerapamilVoclosporin
Severe
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Taking Vpl 5 mg Injection 10 x 2 ml with Voclosporin may significantly increase the blood levels of Voclosporin.

How to manage the interaction:
Although taking Vpl 5 mg Injection 10 x 2 ml and Voclosporin together can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
VerapamilPindolol
Severe
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Taking Pindolol with Vpl 5 mg Injection 10 x 2 ml may increase the risk or severity of side effects.

How to manage the interaction:
Although there may be an interaction, Pindolol can be taken with Vpl 5 mg Injection 10 x 2 ml if prescribed by the doctor. Consult a prescriber if you experience headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
VerapamilNaloxegol
Severe
How does the drug interact with Vpl 5 mg Injection 10 x 2 ml :
Combine use of Naloxegol with Vpl 5 mg Injection 10 x 2 ml may increase the effectiveness of Naloxegol.

How to manage the interaction:
Although taking Naloxegol together with Vpl 5 mg Injection 10 x 2 ml can result in an interaction, they can be taken together if prescribed by your doctor. However, consult a doctor if you experience sweating, tearing, runny nose, chills, diarrhoea, abdominal pain, anxiety, insomnia, irritability, restlessness, and yawning. Do not stop taking any medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit juice: While this is an injection, regular dietary grapefruit juice can interfere with how your body processes this class of medicines; talk to your doctor about your diet.
  • Caffeine: Consuming high amounts of caffeine can counteract the heart-slowing effects of this medicine.
VERAPAMIL-5MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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VERAPAMIL-5MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Consuming Grapefruit juice with Vpl 5 mg Injection 10 x 2 ml can increase the blood levels and effects of Vpl 5 mg Injection 10 x 2 ml . Avoid the Consumption of Grapefruit juice with Vpl 5 mg Injection 10 x 2 ml . Contact a doctor if you experience sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest pain, or difficulty breathing.

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Habit Forming

No

Therapeutic Class

[CALCIUM CHANNEL BLOCKERS]

FAQs

Vpl 5 mg Injection 10 x 2 ml is used to treat abnormal heart rhythms (arrhythmias), such as irregular or rapid heart rates. It can also be used to treat high blood pressure (hypertension) and heart failure.
Vpl 5 mg Injection 10 x 2 ml contains Verapamil, which blocks the entry of calcium into the heart and blood vessel muscles. This relaxes the blood vessels, reduces the workload on the heart, and helps normalise the heart's electrical activity. As a result, it lowers blood pressure and helps control abnormal heart rhythms. During the injection, your healthcare team will monitor your blood pressure and heart rhythm closely. Talk to your doctor if you feel dizzy or have concerns.
It is not recommended to take Vpl 5 mg Injection 10 x 2 ml with other medicines to treat high blood pressure, especially beta-blockers such as atenolol, propranolol, and metoprolol. It may cause an atrioventricular block (a type of heart block) and bradycardia (slow heart rate).
Vpl 5 mg Injection 10 x 2 ml is not suitable for patients with myasthenia gravis (muscle disorders); if you are suffering from myasthenia gravis, inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml .
Vpl 5 mg Injection 10 x 2 ml is contraindicated in people using Ivabradine. So, inform your doctor before receiving Vpl 5 mg Injection 10 x 2 ml if you are on treatment with Ivabradine.
Vpl 5 mg Injection 10 x 2 ml should not be taken in people with any degree of heart failure (unless you have a pacemaker), who are taking beta-blockers, who have severe hypotension (low blood pressure), who have severe bradycardia (low heart rate), and Wolff-Parkinson-White syndrome (rapid heart rate associated with dizziness).
No, this injection must be administered by a trained healthcare professional in a medical setting, such as a hospital or clinic, where your heart can be continuously monitored. Talk to your doctor for more details.
You should avoid drinking alcohol, consuming caffeine, and making sudden movements like standing up too quickly. Talk to your doctor or pharmacist for personalised advice.
This medicine is only used during pregnancy if the potential benefits outweigh the risks. Talk to your doctor to discuss safe options for your heart condition during pregnancy.
Your doctor monitors your heart with an ECG to ensure the medicine is working safely and effectively to correct your heart rhythm without slowing it down too much. Talk to your doctor if you have concerns.
While constipation is a more common side effect of the oral form of this medicine, it is less common with a single intravenous dose. Talk to your doctor or pharmacist if you experience any changes in your bowel habits.
Older adults may be more sensitive to the blood pressure-lowering and heart-slowing effects of this medicine. Doctors usually administer it with extra caution. Talk to your doctor for more information.

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Country of origin

INDIA

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - VPL0001
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