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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Xone ES 1.5 gm Powder For Solution Injection 1's is used to treat life-threatening infections caused by gram-negative bacteria. It contains ceftriaxone (third-generation cephalosporin antibiotic), Disodium Edetate (an Antibiotic Resistance Breaker), and Sulbactam (a beta-lactamase inhibitor). Ceftriaxone works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Disodium Edetate and Sulbactam work by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Thus, Xone ES 1.5 gm Powder For Solution Injection 1's helps treat bacterial infections.

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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Xone ES 1.5 gm Powder For Solution Injection 1's

Xone ES 1.5 gm Powder For Solution Injection 1's belongs to the group of medicines called antibiotics. It is used to treat life-threatening infections caused by gram-negative bacteria. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection.

Xone ES 1.5 gm Powder For Solution Injection 1's contains ceftriaxone (third-generation cephalosporin antibiotic), Disodium Edetate (an Antibiotic Resistance Breaker), and Sulbactam (a beta-lactamase inhibitor). Ceftriaxone works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Disodium Edetate and Sulbactam work by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Thus, Xone ES 1.5 gm Powder For Solution Injection 1's helps treat bacterial infections.

Xone ES 1.5 gm Powder For Solution Injection 1's will be administered by a healthcare professional; do not self-administer. In some cases, Xone ES 1.5 gm Powder For Solution Injection 1's may cause injection site reactions, diarrhoea, rashes, abdominal pain, nausea, and abnormalities in the number of white blood cells and platelets. Most of these side effects of Xone ES 1.5 gm Powder For Solution Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know about your medical and medication history to avoid the occurrence of potential interactions. Xone ES 1.5 gm Powder For Solution Injection 1's should only be given during pregnancy when it clearly necessary. Hence, inform your doctor if you are pregnant, suspect you are pregnant or plan to have a baby; your doctor will weigh the benefits of Xone ES 1.5 gm Powder For Solution Injection 1's therapy against the risks. Breastfeeding should be avoided unless instructed by the doctor. Consumption of alcohol should be avoided while on treatment with Xone ES 1.5 gm Powder For Solution Injection 1's.

Uses of Xone ES 1.5 gm Powder For Solution Injection 1's

Xone ES 1.5 gm Powder For Solution Injection 1's is used in the treatment of serious and resistant bacterial infections. The detailed uses of Xone ES 1.5 gm Powder For Solution Injection 1's are as follows:<br/>• Treats severe bacterial infections: Xone ES 1.5 gm Powder For Solution Injection 1's is effective against a broad range of infections, especially those caused by resistant organisms.<br/>• Manages respiratory tract infections: It helps treat bacterial pneumonia, bronchitis, and other lower respiratory tract infections.<br/>• Effective in urinary tract infections: Xone ES 1.5 gm Powder For Solution Injection 1's is used in the treatment of complicated UTIs, including those caused by multidrug-resistant bacteria.<br/>• Controls skin and soft tissue infections: It treats cellulitis, abscesses, and wound infections.<br/>• Treats bone and joint infections: Xone ES 1.5 gm Powder For Solution Injection 1's is used in osteomyelitis and septic arthritis where bacterial resistance is a concern.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Xone ES 1.5 gm Powder For Solution Injection 1's will be administered by a healthcare professional.• Do not self-administer it.

Medicinal Benefits

Xone ES 1.5 gm Powder For Solution Injection 1's contains ceftriaxone (third-generation cephalosporin antibiotic), Disodium Edetate, and Sulbactam (a beta-lactamase inhibitor). Xone ES 1.5 gm Powder For Solution Injection 1's is a unique and patented anti-infective product that is primarily used to treat potentially fatal illnesses caused by gram-negative bacteria. Ceftriaxone works by preventing the production of the bacterial cell wall (a protective covering required for survival). As a result, the bacterial cell wall is damaged, and the organism (bacteria) is killed. Disodium Edetate and Sulbactam function by lowering bacterial resistance and increasing Ceftizoxime action against bacteria.

How Xone ES 1.5 gm Powder For Solution Injection 1's Works

Xone ES 1.5 gm Powder For Solution Injection 1's contains ceftriaxone (third-generation cephalosporin antibiotic), Disodium Edetate (an Antibiotic Resistance Breaker), and Sulbactam (a beta-lactamase inhibitor). Ceftriaxone works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Disodium Edetate and Sulbactam work by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Thus, Xone ES 1.5 gm Powder For Solution Injection 1's helps treat bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Xone ES 1.5 gm Powder For Solution Injection 1's out of reach and sight of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Xone ES 1.5 gm Powder For Solution Injection 1's

As Xone ES 1.5 gm Powder For Solution Injection 1's is a parenteral formulation, the chance of overdose may be less. In case of overdose, patients must be closely monitored for signs or symptoms of adverse reactions and appropriate symptomatic treatment instituted. Signs and symptoms of an overdose of Xone ES 1.5 gm Powder For Solution Injection 1's may include Neurological adverse reactions, including convulsions.

Drug Warnings

It is recommended not to use if you are allergic to any component in Xone ES 1.5 gm Powder For Solution Injection 1's. If you are pregnant or breastfeeding, discuss with your doctor about the risks and benefits before taking Xone ES 1.5 gm Powder For Solution Injection 1's. For effective outcomes, it is recommended that you complete the entire course of Xone ES 1.5 gm Powder For Solution Injection 1's as prescribed by your doctor. If you are received or scheduled for vaccines, inform your doctor before receiving Xone ES 1.5 gm Powder For Solution Injection 1's. Xone ES 1.5 gm Powder For Solution Injection 1's should be used cautiously in people with Clostridium difficile-associated diarrhoea and hyperbilirubinemia (too much bilirubin in the blood), cardiovascular dysfunction, and tuberculosis. So, before taking the Xone ES 1.5 gm Powder For Solution Injection 1's, inform your doctor about all of your medical problems, sensitivities, and medications.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Xone ES 1.5 gm Powder For Solution Injection:
Co-administration of Calcium chloride with Xone ES 1.5 gm Powder For Solution Injection can increase the risk of side effects.

How to manage the interaction:
Taking Xone ES 1.5 gm Powder For Solution Injection with Calcium chloride is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Xone ES 1.5 gm Powder For Solution Injection:
Co-administration of Calcium gluconate with Xone ES 1.5 gm Powder For Solution Injection can increase the risk of adverse effects.

How to manage the interaction:
Taking Xone ES 1.5 gm Powder For Solution Injection with Calcium gluconate is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
CeftriaxoneCholera, live attenuated
Severe
How does the drug interact with Xone ES 1.5 gm Powder For Solution Injection:
Taking the cholera vaccine after or along with Xone ES 1.5 gm Powder For Solution Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Xone ES 1.5 gm Powder For Solution Injection and Cholera, live attenuated together can evidently cause an interaction, it can be taken if your doctor has suggested it. To ensure adequate vaccine response, you should not receive cholera vaccine, live until at least 14 days after you complete your antibiotic therapy. In case you experience any unusual side effects, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Probiotics should be taken after taking the full course of Xone ES 1.5 gm Powder For Solution Injection 1's to restore healthy bacteria that may have been killed in the intestine. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should be included in your diet.
  • Avoid intake of alcoholic beverages with Xone ES 1.5 gm Powder For Solution Injection 1's as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid Xone ES 1.5 gm Powder For Solution Injection 1's in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Xone ES 1.5 gm Powder For Solution Injection 1's Substitute

Substitutes safety advice
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Alcohol

Caution

Avoid taking alcohol while using Xone ES 1.5 gm Powder For Solution Injection 1's since it may worsen the disease condition.

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Pregnancy

Caution

Xone ES 1.5 gm Powder For Solution Injection 1's should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Xone ES 1.5 gm Powder For Solution Injection 1's.

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Breast Feeding

Caution

Inform the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the medicine to the mother.

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Driving

Caution

Xone ES 1.5 gm Powder For Solution Injection 1's usually does not affect your ability to drive or operate machinery. However, do not drive or operate machinery if you feel sleepy or dizzy after taking medicine.

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Liver

Caution

Caution should be exercised while using Xone ES 1.5 gm Powder For Solution Injection 1's in patients with liver disease. Inform your doctor before receiving Xone ES 1.5 gm Powder For Solution Injection 1's if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

The use of Xone ES 1.5 gm Powder For Solution Injection 1's is contraindicated in patients with anuria and severe renal dysfunction. Caution should be exercised while using Xone ES 1.5 gm Powder For Solution Injection 1's in patients with mild to moderate kidney disease. Inform your doctor before receiving Xone ES 1.5 gm Powder For Solution Injection 1's if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

The safety and effectiveness of Xone ES 1.5 gm Powder For Solution Injection 1's in children have not been established.

Have a query?

FAQs

Xone ES 1.5 gm Powder For Solution Injection 1's is used to treat Bacterial infections.

Xone ES 1.5 gm Powder For Solution Injection 1's contains ceftriaxone, Disodium Edetate, and Sulbactam (a beta-lactamase inhibitor). Ceftriaxone works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Disodium Edetate and Sulbactam works by decreasing bacterial resistance and enhancing the activity of Ceftizoxime against the bacteria. Thus, Xone ES 1.5 gm Powder For Solution Injection 1's helps treat bacterial infections.

Xone ES 1.5 gm Powder For Solution Injection 1's may cause Clostridium difficile-associated diarrhoea (CDAD). Antibiotic treatment alters the normal flora, leading to overgrowth of Clostridium difficile, which causes diarrhoea. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you experience prolonged diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

No, it can only be used to treat specific medical diseases, most notably potentially lethal illnesses caused by gram-negative bacteria.

Inform your doctor if you do not feel better even after finishing the full course of treatment. If the symptoms worsen while using this medicine, consult your doctor right away.

Usually, Xone ES 1.5 gm Powder For Solution Injection 1's starts working soon after taking it. However, it may take a few days to kill all the harmful bacteria and make you feel better.

Disodium Edetate is usually contraindicated in patients with active tuberculosis or healed calcified tubercular lesions. Edetate disodium forms stable soluble complexes with calcium. So, inform your doctor before receiving Xone ES 1.5 gm Powder For Solution Injection 1's if you have had tuberculosis.

Inform the doctor about your detailed medical and surgical history, if you have liver, kidney or heart disease or fits and if you are pregnant, breastfeeding or planning to have a baby. Inform your doctor if you are taking any other medicines including supplements or herbal products as Xone ES 1.5 gm Powder For Solution Injection 1's may interact with other medicines. Also, let your doctor know if you are stopping any medicine.

Xone ES 1.5 gm Powder For Solution Injection 1's is usually administered in a hospital under the doctor’s supervision. Your doctor will decide the dosage and administration.

Country of origin

India

Manufacturer/Marketer address

Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - XON0052

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