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compositionComposition:CAPECITABINE-150MG
prescription
Prescription Medicine
info
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Xortib 150mg Tablet is used to treat breast, colon and stomach cancer. It contains Capecitabine which works by interfering with the growth of cancer cells. In some cases, this medicine may cause side effects such as nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, and mouth ulcers. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CAPECITABINE-150MG

Manufacturer/Marketer :

Biocon Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Xortib 150mg Tablet

Xortib 150mg Tablet is a prescription oral medication used to treat certain types of cancer, including colon, rectal, and breast cancer. It works by targeting rapidly dividing cancer cells to slow down or stop their growth. Your doctor will determine if Xortib 150mg Tablet is suitable for your specific type of cancer.

You will typically take this medication twice a day, in the morning and evening, consistently at the same times. It is very important to take each dose within 30 minutes after finishing a meal to help your body absorb it properly. Staying well-hydrated and eating a balanced diet can help support your body during this treatment.

While taking Xortib 150mg Tablet, you may experience some common side effects such as diarrhea, nausea, or redness and peeling on your hands and feet. If you experience severe diarrhea, vomiting, or a high fever, you must contact your doctor immediately, as these can become serious quickly.

Talk to your doctor if you have a history of kidney disease, liver damage, heart conditions, or a known enzyme deficiency called DPD deficiency. Do not take this if you have a complete lack of the DPD enzyme, as this can lead to severe, life-threatening reactions. Xortib 150mg Tablet should not be taken by pregnant or breastfeeding individuals due to the risk of harm to the baby.

This medication can interact with other treatments, including blood thinners, certain antacids, and seizure medicines, which may increase your risk of severe bleeding or other side effects. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist to discuss specific precautions and monitoring needed during your therapy.

Uses of Xortib 150mg Tablet

Xortib 150mg Tablet is used in the treatment of Breast cancer, rectal, and colon cancer. The detailed uses of Xortib 150mg Tablet are as follows:

  • Breast Cancer: It is used to treat advanced or metastatic breast cancer, either alone or combined with other medications, when other standard treatments have stopped working.
  • Colorectal Cancer: Xortib 150mg Tablet helps manage and treat advanced or metastatic colorectal cancer that has spread to other areas of the body.
  • Colon Cancer: Xortib 150mg Tabletis used after surgery to help prevent the cancer from returning in patients who have had stage III colon cancer completely removed.

 

Key Benefits

Xortib 150mg Tablet helps treat certain types of cancer by slowing or stopping the growth of cancer cells. As part of a comprehensive cancer treatment plan, it helps control disease progression and supports improved treatment outcomes.
Benefits may include:

  • Helps slow or stop the growth of certain cancer cells.
  • May help shrink tumours and delay the progression of cancer.
  • Supports treatment after surgery to help reduce the risk of cancer recurrence in appropriate patients.
  • Helps improve disease control as part of a comprehensive cancer treatment plan.
  • Provides the convenience of oral treatment, reducing the need for frequent intravenous chemotherapy visits.
  • Supports overall quality of life during cancer treatment by allowing greater flexibility in daily routines.

Directions for Use

  • Xortib 150mg Tablet should be taken within 30 minutes after a meal.
  • It is recommended to take Xortib 150mg Tablet twice daily or as advised by your doctor.
  • Swallow Xortib 150mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Xortib 150mg Tablet Works

Capecitabine is an oral medicine that acts as a prodrug, meaning it is inactive when you swallow it. Once absorbed into your digestive system, it travels through your body and is converted into its active, cancer-fighting form primarily inside tumor cells. This conversion relies on specific enzymes that are highly active in cancer tissue. Once converted, the active medicine interferes with the production of DNA and RNA, which cancer cells need to grow, repair, and multiply. By disrupting this process, the medicine stops the cancer cells from dividing, leading to their destruction while causing less direct exposure to healthy body tissues compared to some other treatments.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Xortib 150mg Tablet to avoid unpleasant side effects. Alcohol intake, along with Xortib 150mg Tablet, may cause increased drowsiness.

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Pregnancy

Unsafe

Xortib 150mg Tablet should not be used during pregnancy because it causes harm to the fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking fluorouracil and for at least six months afterwards. Please consult your doctor about any concerns regarding this.

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Breast Feeding

Unsafe

Xortib 150mg Tablet should not be taken during breastfeeding as it passes into the breastmilk and may harm the nursing baby. It is contraindicated in breastfeeding mothers.

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Driving

Unsafe

Xortib 150mg Tablet may cause dizziness and drowsiness, do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

If you have had a history or evidence of any liver-related diseases, please consult the doctor before taking Xortib 150mg Tablet. Your doctor will weigh the benefits and potential risks before prescribing Xortib 150mg Tablet.

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Kidney

Caution

If you have had a history or evidence of any kidney-related diseases, please consult the doctor before taking Xortib 150mg Tablet. Your doctor will weigh the benefits and potential risks before prescribing Xortib 150mg Tablet.

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Children

Unsafe

Xortib 150mg Tablet should not be used by children, as efficacy and safety have not been established.

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Heart

Caution

Xortib 150mg Tablet should be used with extreme caution due to the risk of cardiovascular problems. Please inform your physician if you have any concerns.

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Geriatrics

Safe if prescribed

Xortib 150mg Tablet is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Xortib 150mg Tablet

If you take more than your prescribed dose, seek emergency medical attention or contact a poison control center immediately. An overdose can cause severe nausea, diarrhea, bleeding, or infections.

Diet & Lifestyle Advise

  • Stay hydrated: Drink 8 to 10 glasses of water or clear fluids daily to prevent dehydration, especially if you experience mild diarrhea or nausea.
  • Protect your skin: Apply a thick, alcohol-free moisturizing cream to your hands and feet regularly. Avoid hot water, vigorous rubbing, and tight footwear to reduce the risk of hand-foot syndrome.
  • Eat smaller meals: Choose small, frequent, bland meals (such as bananas, rice, applesauce, and toast) to ease digestion and manage nausea. Avoid spicy, fatty, or highly acidic foods.
  • Practice gentle oral care: Use a soft-bristle toothbrush and rinse your mouth with water or a mild baking soda solution after meals to prevent mouth sores.
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Have a query?

How Soon It Starts Working

  • The time required for Xortib 150mg Tablet to start to work: The time required for Xortib 150mg Tablet to show its action is unknown.
  • The time for which the effects of Xortib 150mg Tablet last: The duration of action for Xortib 150mg Tablet is clinically unknown.

What if you forget to take Xortib 150mg Tablet

If you miss a dose, skip the missed dose entirely. Take your next scheduled dose at your regular time. Do not take a double dose to make up for the missed one, and consult your doctor or pharmacist if you have concerns.

Storage

•Store Xortib 150mg Tablettablets at room temperature, ideally between 20°C to 25°C (68°F to 77°F) •Keep the medicine in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Inspect the medicine before use: Do not take the tablets if they are cracked, chipped, broken, or otherwise damaged.
  • Separate antacids from your dose: Avoid taking antacids containing aluminum or magnesium hydroxide within 2 hours of Xortib 150mg Tablet, as they may reduce its absorption and effectiveness.
  • Use effective contraception: Use reliable birth control during treatment and for the recommended period after your final dose, as Xortib 150mg Tablet can harm an unborn baby. Follow your doctor's advice regarding the appropriate duration of contraception.
  • Protect your skin from sunlight: Xortib 150mg Tablet may increase your sensitivity to sunlight. Limit direct sun exposure, wear protective clothing, and apply a broad-spectrum sunscreen when outdoors.
  • Reduce the risk of hand-foot skin reactions: Avoid long, hot baths or showers, as heat and friction can worsen hand-foot skin reactions. Keep your hands and feet cool, moisturized, and protected during treatment.

verifiedApollotooltip
  • Blood thinners (e.g., warfarin): Taking these medicines alongside Xortib 150mg Tablet may significantly increase the risk of serious bleeding. Your doctor may monitor your blood clotting closely and adjust your treatment if needed.
  • Anti-seizure medicines (e.g., phenytoin): Xortib 150mg Tablet may increase phenytoin levels in the body, raising the risk of side effects and toxicity.
  • Antacids: Certain antacids may increase the absorption of Xortib 150mg Tablet, which could increase the risk of side effects. Consult your doctor or pharmacist before taking these medicines together.

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verifiedApollotooltip
  • Food: Always take Xortib 150mg Tablet within 30 minutes after finishing a meal. Taking it on an empty stomach may affect how the medicine is absorbed and increase the risk of side effects.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

FAQs

Xortib 150mg Tablet belongs to a group of medicines known as anti-cancer‚ used to treat breast, colon and stomach cancer.
Xortib 150mg Tablet interferes with the growth of the cancer cells genetic material (DNA). This slows the growth of cancer cells and eventually kills them.
Xortib 150mg Tablet can make your skin more sensitive to the harmful effects of sunlight. Hence it is advised to wear protective clothing while using Xortib 150mg Tablet. It is recommended to avoid tanning booths and sunlamps.
Yes, Xortib 150mg Tablet may change the results of blood tests and other laboratory tests. Inform the person doing the tests that you are taking Xortib 150mg Tablet as regular monitoring of liver and kidney functions tests, electrolyte levels and blood cells is required.
Yes, Xortib 150mg Tablet commonly affects the hair by making it thin, which further causes hair loss. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Xortib 150mg Tablet. These effects are not long-lasting and may return after some time. If it matters to you, then consult your doctor for further advice.
Xortib 150mg Tablet may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Xortib 150mg Tablet.
Your doctor will decide the number of treatment cycles and the frequency of Xortib 150mg Tablet to be taken, depending on the type and stage of the cancer being treated.
No, it is advised not to use these two medicines at the same time as they may cause severe drug reactions. Maintain a gap of at least four weeks between the last dose of brivudine and the first dose of Xortib 150mg Tablet.
Xortib 150mg Tablet contains Capecitabine, an anti-cancer medication used to treat breast cancer, stomach, rectal and colon cancer.
Xortib 150mg Tablet may cause side-effects such as nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, decreased blood cells (red cells, white cells, and platelets), mouth ulcers, blisters on fingers/feet in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
No, you should not crush, chew, or split Xortib 150mg Tablettablets. They must be swallowed whole with water to ensure you receive the correct dose and to prevent exposure to the active medicine. If you have difficulty swallowing, talk to your doctor or pharmacist for alternative options.
Do not take an extra dose to replace the one you vomited. Simply wait and take your next scheduled dose at the normal time. Inform your doctor as soon as possible if you frequently vomit after taking your medication. Talk to your doctor for guidance on managing nausea.
Taking Xortib 150mg Tabletshortly after a meal helps your body absorb the medication properly and safely. It also helps reduce the likelihood of experiencing stomach irritation and nausea. Talk to your doctor or pharmacist if you struggle to eat before your doses.
Hand-foot syndrome is a skin reaction that causes redness, swelling, tingling, numbness, or peeling on the palms of your hands and soles of your feet. If you notice these symptoms becoming painful or interfering with your daily activities, talk to your doctor immediately.
It is best to avoid or strictly limit alcohol while taking Xortib 150mg Tablet. Alcohol can worsen stomach irritation, dehydration, and liver strain, which are already potential side effects of your treatment. Talk to your doctor or pharmacist before drinking alcohol.
You should avoid getting live vaccines during your treatment, as Xortib 150mg Tabletcan weaken your immune system and increase the risk of infection from the vaccine. Always talk to your doctor before receiving any vaccine or booster shot.
Xortib 150mg Tablet can cause harm to an unborn baby and may affect fertility in both men and women. Reliable birth control must be used by both male and female patients during treatment and for a period after stopping. Talk to your doctor if you have concerns about family planning.
Your healthcare team will monitor your progress through regular checkups, blood tests, and imaging scans (like CT or MRI scans) to see how your body is responding. Do not stop taking the medicine unless directed, and talk to your doctor about your treatment progress.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - XO33277
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