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compositionComposition:CEFTAZIDIME-1000MG
prescription
Prescription Medicine
info
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Xorzid 1000mg Injection is used to treat bacterial infections. It contains Ceftazidime which works by damaging the bacterial cell wall and killing bacteria. In some cases, this medicine may cause side effects such as redness or swelling at the site of injection or diarrhoea. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFTAZIDIME-1000MG

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Xorzid 1000mg Injection

Xorzid 1000mg Injection is a prescription antibiotic injection used to treat serious bacterial infections throughout the body. It is commonly prescribed to treat infections in the lungs, skin, stomach, and urinary tract. This medicine is typically injected into a vein or muscle under medical supervision.

Because this medicine is given as an injection, you do not need to worry about taking it with or without food. However, it is vital to receive this treatment at consistent times as directed by your doctor to keep a steady level of the medicine in your body. To support your recovery, drink plenty of fluids and get adequate rest while receiving this treatment.

Most people tolerate this injection well, but some may experience mild side effects like swelling at the injection site or stomach upset. If you develop severe watery diarrhea, a skin rash, or difficulty breathing, you must seek medical help immediately. Always consult your doctor if you experience any unusual symptoms during your treatment.

Do not take this if you have had a severe allergic reaction to similar antibiotics in the past. Before starting this medicine, tell your doctor if you have kidney disease or a history of bowel inflammation.

This medicine can interact with certain other treatments, such as strong water pills, which can increase the risk of kidney strain. If you are pregnant, breastfeeding, or managing health conditions as an older adult, consult your healthcare provider to ensure this treatment is safe for you.

Uses of Xorzid 1000mg Injection

Your doctor may prescribe this medicine to treat several conditions, including:

  • Severe lung infections (pneumonia): Stops the growth of bacteria deep in the lungs to help you breathe easier.
  • Complicated urinary tract infections: Clears stubborn bacterial infections in the kidneys and bladder.
  • Skin and soft tissue infections: Destroys bacteria causing deep, painful infections in the skin layers.
  • Intra-abdominal infections: Treats serious bacterial infections inside the stomach cavity and surrounding organs.
  • Meningitis: Fights dangerous bacterial infections affecting the membranes around the brain and spinal cord.
  • Bloodstream infections: Targets and eliminates bacteria that have entered the blood, preventing widespread organ damage.
  • Pseudomonas infection: Helps treat serious infections caused by Pseudomonas aeruginosa, a type of bacteria that can be difficult to treat

Key Benefits

Xorzid 1000mg Injection provides the following benefits when used as prescribed:

  • Fast-Acting Infection Relief: By being injected directly into the body, Xorzid 1000mg Injection provides fast-acting relief because it bypasses the digestive system and enters the bloodstream immediately. This rapid action helps stop severe, fast-spreading bacterial infections from causing further damage to vital organs.
  • Targets Resistant Bacteria: It is highly effective against hard-to-treat bacteria that are resistant to other standard antibiotics.
  • Supports Faster Recovery: Patients typically experience a steady reduction in fever, pain, and other infection symptoms, helping them recover their strength and return to daily activities faster.
     
Side effects of Xorzid 1000mg Injection
Managing Medication-Triggered Thrombophlebitis (Inflammation of a vein): A Step-by-Step Guide:
  • If you have symptoms such as pain, swelling, redness, or warmth in your veins after taking medication, contact your doctor right once. Share information about your symptoms, medication regimen, and medical history.
  • Your doctor will then assess your medication regimen to determine if it's contributing to the thrombophlebitis. This assessment will help identify the best course of action to manage your condition and prevent further complications.
  • Your doctor may suggest certain diet and lifestyle changes to help manage your condition. This may include increasing your intake of foods rich in omega-3 fatty acids, staying hydrated, exercising regularly, and maintaining a healthy weight. Your doctor may also advise medications to reduce inflammation, prevent blood clots, or manage pain if necessary.
  • If your condition does not improve or persists, consult your doctor and report your condition. Your doctor will assess your progress, adjust your treatment plan if necessary, and provide appropriate advice to ensure the best possible outcome.
  • If you notice swelling, pain, redness, or pus at the injection site, contact your doctor for advice and appropriate care.
  • Use ice packs on the injection site for at least 20 minutes multiple times a day.
  • Rest the affected area and elevate it to reduce inflammation if possible.
  • Avoid intense physical activity that could worsen the injection site.
  • If you need regular injections, try using different spots to avoid severe inflammation in one place.
  • Consider using medications like ibuprofen or paracetamol to relieve pain, and hydrocortisone cream or anti-itch lotion to ease swelling and discomfort.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Eat foods rich in vitamins C and E, and healthy fats.
  • Consider soft foods like smoothies, soups, and scrambled eggs.
  • Take supplements like vitamins C and E, zinc, and omega-3 fatty acids under medical supervision.
  • Include anti-inflammatory foods like omega-3 rich foods, berries, leafy greens, and spices.
  • Avoid allergens and consider an elimination diet.
  • Practice gentle skin care with non-irritating cleansers and moisturizers.
  • Keep skin well-moisturized with fragrance-free products.
  • Monitor for complications like infection and temperature regulation.
  • Let your doctor know if there are unsual symptoms after taking the medication, such as red patches on your skin.
  • Your doctor may change your medication, lower the dose, or stop the treatment to help manage the symptoms.
  • Avoid heavy physical activity and get plenty of rest to prevent further worsening of the symptoms.
  • Apply cold packs to the affected areas for relief.
  • Keep yourself hydrated or take supplements to get enough vitamins.
  • Over-the-counter pain relievers can help with discomfort.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Xorzid 1000mg Injection will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Xorzid 1000mg Injection Works

Ceftazidime belongs to a class of antibiotics that target the protective outer layer of bacteria. Bacteria must continuously build and repair their cell walls to survive and multiply in the human body. This medicine works by blocking the specific proteins that bacteria use to build these protective walls. Without a strong cell wall, the bacteria cannot withstand internal pressure, causing them to rupture and die. Because human cells do not have cell walls, this process specifically targets and destroys the invading bacteria without harming your own cells.
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Alcohol

Caution

The interaction of Xorzid 1000mg Injection with alcohol is unknown. Please consult a doctor before consuming alcohol while using Xorzid 1000mg Injection.

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Pregnancy

Caution

Xorzid 1000mg Injection is a category B pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Xorzid 1000mg Injection may be excreted in human milk in small amounts. Therefore, it is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Xorzid 1000mg Injection may cause dizziness. Therefore, avoid driving if you feel dizzy after taking Xorzid 1000mg Injection.

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Liver

Caution

Take Xorzid 1000mg Injection with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Xorzid 1000mg Injection with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Xorzid 1000mg Injection should be used in children only in doses as prescribed by a doctor.

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Heart

Caution

Xorzid 1000mg Injection should be administered with caution in patients with heart problems. Therefore, please talk to your doctor before receiving Xorzid 1000mg Injection.

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Geriatrics

Caution

Xorzid 1000mg Injection should be administered with caution to elderly patients due to an increased risk of side effects. Please consult your doctor before receiving Xorzid 1000mg Injection.

What if I have taken an overdose of Xorzid 1000mg Injection

If you suspect an overdose, or if you experience severe symptoms like seizures or confusion after receiving an injection, seek emergency medical care.

Diet & Lifestyle Advise

  • Probiotic and Gut Health: Take a high-quality probiotic or eat fermented foods like yogurt (separated by a few hours from your injection) to help restore healthy gut bacteria.
  • Stay Well Hydrated: Stay well-hydrated by drinking plenty of water to help your kidneys process and clear the medicine efficiently.
  • Get Adequate Rest: Get plenty of rest to support your immune system while your body fights off the infection.
  • Avoid Alcohol: Avoid drinking alcohol, as it can stress your liver and cause dehydration during your recovery.
health query

Have a query?

How Soon It Starts Working

The time required for Xorzid 1000mg Injection to start to work: Xorzid 1000mg Injection ideally shows its action within 1 hour after administration. The time for which the effects of Xorzid 1000mg Injection last: The effect of Xorzid 1000mg Injection lasts for 8 to 12 hours.

What if you forget to take Xorzid 1000mg Injection

If you miss an injection appointment or miss a dose at home, contact your doctor or healthcare provider immediately for instructions. Do not inject a double dose to make up for a missed one.

Storage

• Store dry powder vials at room temperature, between 20°C to 25°C (68°F to 77°F), away from direct light and heat.

Drug Warnings

  • Inspect Vial: Always inspect the vial before use and discard it if you see floating particles, cloudiness, or unusual discoloration.
  • Injection Site Rotation: Rotate your injection sites regularly to reduce the risk of pain, swelling, or tissue damage at the injection area.
  • Sterile Needle Use: Use a new, sterile needle and syringe for every single injection to prevent serious blood infections.
  • Finish Course: Complete the entire prescribed course of treatment, even if you feel completely better, to prevent the infection from returning.
  • Kidney Warning: Inform your doctor immediately if you have kidney disease, as your dose may need to be adjusted to prevent side effects.

Drug-Drug Interactions

verifiedApollotooltip
  • Strong water pills (like furosemide): May increase the risk of kidney damage when used together.
  • Certain other antibiotics (like aminoglycosides): Can increase stress and potential damage to the kidneys.
  • Oral typhoid vaccine: This antibiotic may decrease the effectiveness of live bacterial vaccines.
CeftazidimeBCG vaccine
Critical
CeftazidimeCholera vaccines
Severe

Drug-Drug Interactions

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CeftazidimeBCG vaccine
Critical
How does the drug interact with Xorzid 1000mg Injection:
When BCG vaccine is used with Xorzid 1000mg Injection, its effectiveness may be reduced.

How to manage the interaction:
Taking Xorzid 1000mg Injection with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. In case you experience any unusual side effects, consult a doctor. Do not discontinue any medications without consulting a doctor.
CeftazidimeCholera vaccines
Severe
How does the drug interact with Xorzid 1000mg Injection:
Taking the cholera vaccine after or along with Xorzid 1000mg Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although there is a possible interaction between Xorzid 1000mg Injection and Cholera vaccines, you can take these medicines together if prescribed by your doctor. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. Do not stop using any medications without consulting a doctor.
CeftazidimeCholera, live attenuated
Severe
How does the drug interact with Xorzid 1000mg Injection:
Taking the cholera vaccine after or along with Xorzid 1000mg Injection may reduce the activity of the vaccine.

How to manage the interaction:
Although taking Xorzid 1000mg Injection with Cholera, live attenuated can possibly result in an interaction, but it can be taken if your doctor has advised it. You should wait at least 14 days after finishing your antibiotic treatment before receiving the cholera vaccine in order to ensure an appropriate immune response. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Xorzid 1000mg Injection when used as directed.     
 

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Xorzid 1000mg Injection contains Ceftazidime, an antibiotic that works by damaging the bacterial cell wall (protective covering) that is necessary for their survival. Thereby, kills bacteria.
Xorzid 1000mg Injection may be used to treat meningitis (inflammation of membranes covering the brain and spinal cord) caused by bacterial infection. Xorzid 1000mg Injection is an antibiotic that kills bacteria and prevents the spread of infection.
Xorzid 1000mg Injection may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, avoid taking Xorzid 1000mg Injection and consult a doctor immediately.
You are not recommended to take Xorzid 1000mg Injection with furosemide as co-administration of these two medicines may increase the risk of kidney problems, especially in patients with kidney impairment and also when Xorzid 1000mg Injection is given in high doses. However, please consult your doctor before taking Xorzid 1000mg Injection with other medicines.
Xorzid 1000mg Injection is not used to treat viral infections. Xorzid 1000mg Injection is an antibiotic that is used to treat only bacterial infections.
You are not recommended to stop taking Xorzid 1000mg Injection without consulting your doctor as it may worsen the infection or cause recurring symptoms. Therefore, take Xorzid 1000mg Injection for as long as your doctor has prescribed it and if you experience any difficulty while taking Xorzid 1000mg Injection, please consult your doctor.
Xorzid 1000mg Injection belongs to a class of antibiotics used to treat several bacterial infections.
Xorzid 1000mg Injection contains Ceftazidime, an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria.
Common side effects of Xorzid 1000mg Injection may include redness and swelling along with a vein, a red raised skin rash that may be itchy, burning, painful, inflammation, or swelling at the site of injection, or diarrhoea. Most of these side effects of Xorzid 1000mg Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
It is injected directly into a vein or deep into a muscle by a healthcare professional, or by yourself at home after proper training. Talk to your doctor.
Yes, if your healthcare provider decides it is appropriate and trains you thoroughly on safe injection techniques. Talk to your doctor.
Mild redness and pain can happen, but if the swelling, redness, or pain worsens or becomes hot to the touch, contact your healthcare provider. Talk to your doctor.
It is best to avoid alcohol while recovering from a serious infection, as it can dehydrate your body and affect your recovery. Talk to your doctor.
This medicine should only be used during pregnancy if clearly needed and prescribed by your healthcare provider. Talk to your doctor.
Contact your healthcare provider immediately to get advice on when to receive your next dose. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.275 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Ceftazidime Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. Drugs H. Ceftazidime Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2025 [Accessed on 30 Sep 2025]Check here
  4. FORTAZ® (ceftazidime for injection) USP [Internet]. Accessdata.fda.gov. 2025 [Accessed on 30 Sep 2025]Check here
  5. Ceftazidime 1g Powder for Solution for Injection or Infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 30 Sep 2025]Check here
  6. Ceftazidime 1g Powder for Solution for Injection or Infusion - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 30 Sep 2025]Check here
  7. NIH National Library of Medicine, National center for biotechnology information. Pubchem. Ceftazidime. [Accessed on 15th July 2022]Check here

Country of origin

India
Other Info - XO91068
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