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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

ZECYTE 250MG TABLET is an anti-androgen medicine used to treat prostate cancer. It contains Abiraterone, which is in a class of medications called androgen biosynthesis inhibitors. It works by decreasing the amount of certain hormones in the body. Common side effects of ZECYTE 250MG TABLET may include nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain.

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Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About ZECYTE 250MG TABLET

ZECYTE 250MG TABLET is an anti-androgen medicine used in the treatment of prostate cancer. It is used to treat metastatic castration-resistant prostate cancer (a condition where cancer does not get controlled with hormonal therapy) and metastatic castration-sensitive prostate cancer (a condition where cancer has spread to other parts of the body but can be controlled) in men. Prostate cancer is a condition that occurs when the prostate gland cells increase abnormally. Symptoms may include difficulty in urinating, pain, numbness, etc.

ZECYTE 250MG TABLET contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. ZECYTE 250MG TABLET works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. 

ZECYTE 250MG TABLET may cause certain side effects such as nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite and groin pain. These side effects usually disappear without any medical attention. However, if these side effects persist, inform your doctor. Take this medicine as advised by your doctor. It should be taken on an empty stomach at least 2 hours before or after meals. Your doctor will decide the dose of the medicine based on the severity of your disease.

ZECYTE 250MG TABLET should be avoided if you are allergic to it. Inform your doctor if you have any pre-existing or a history of liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention before taking ZECYTE 250MG TABLET. ZECYTE 250MG TABLET is not recommended for use in women and children as the safety and efficacy of this medicine are not established. Inform your doctor of all your ongoing medications to avoid interactions. This medicine is used in combination with prednisolone for the treatment of prostate cancer. 

Uses of ZECYTE 250MG TABLET

Treatment of Prostate Cancer

Directions for Use

ZECYTE 250MG TABLET should be taken on an empty stomach at least two hours before or after a meal. It is advised not to take more than the recommended dose of medicine. Swallow the medicine as a whole with a glass of water. Do not chew or crush or break the medicine.

Medicinal Benefits

ZECYTE 250MG TABLET contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes increase of cancer cells in prostate gland. ZECYTE 250MG TABLET works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer. ZECYTE 250MG TABLET is used in combination with prednisolone for the treatment of prostate cancer. It is mainly intended for use in men only.

How ZECYTE 250MG TABLET Works

ZECYTE 250MG TABLET contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. Testosterone is a natural hormone produced by the body. This causes an increase in cancer cells in the prostate gland. ZECYTE 250MG TABLET works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zecyte 250mg Tablet
  • If you have discomfort, illness, or unease after taking medication, seek medical attention.
  • Your treatment plan may be modified, including adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage discomfort, follow your doctor's advice, like getting plenty of rest, or staying hydrated, and practising stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to manage the discomfort effectively.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

What if I have taken an overdose of ZECYTE 250MG TABLET

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of ZECYTE 250MG TABLET may include fast or irregular heartbeat, lightheadedness, dizziness, or fainting, shortness of breath or difficulty breathing, swelling of the feet, ankles, or lower legs, and unexplained weight gain. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

ZECYTE 250MG TABLET should be avoided if you are allergic to it or any other components present in it. Inform your doctor if you have/had any conditions like liver/kidney disease, cardiovascular disease, adrenocortical insufficiency, hypokalemia, hypoglycaemia, fluid retention or taking any other medicines before taking ZECYTE 250MG TABLET as it may cause serious side effects. ZECYTE 250MG TABLET is not recommended for use in women and children as the safety and efficacy of this medicine are not established. This medicine is used in combination with prednisolone for the treatment of prostate cancer.

Drug-Drug Interactions

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AbirateroneThioridazine
Critical
AbirateroneSaquinavir
Critical

Drug-Drug Interactions

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AbirateroneThioridazine
Critical
How does the drug interact with Zecyte 250mg Tablet:
Taking Zecyte 250mg Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zecyte 250mg Tablet and Thioridazine together is not recommended and can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneSaquinavir
Critical
How does the drug interact with Zecyte 250mg Tablet:
Taking Zecyte 250mg Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zecyte 250mg Tablet and Saquinavir together is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneEliglustat
Critical
How does the drug interact with Zecyte 250mg Tablet:
Coadministration of Zecyte 250mg Tablet with Eliglustat can increase the levels of Eliglustat in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Zecyte 250mg Tablet with Eliglustat is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AbirateroneMesoridazine
Critical
How does the drug interact with Zecyte 250mg Tablet:
Taking Zecyte 250mg Tablet with Mesoridazine can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Zecyte 250mg Tablet and Mesoridazine together is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneZiprasidone
Critical
How does the drug interact with Zecyte 250mg Tablet:
Taking Zecyte 250mg Tablet with ziprasidone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Zecyte 250mg Tablet and ziprasidone, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
AbirateroneVemurafenib
Severe
How does the drug interact with Zecyte 250mg Tablet:
Taking Zecyte 250mg Tablet with Vemurafenib can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zecyte 250mg Tablet with Vemurafenib together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneOsimertinib
Severe
How does the drug interact with Zecyte 250mg Tablet:
Taking Zecyte 250mg Tablet with Osimertinib can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Zecyte 250mg Tablet with Osimertinib together can result in an interaction; it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat. Do not discontinue any medications without consulting a doctor.
AbirateroneVenetoclax
Severe
How does the drug interact with Zecyte 250mg Tablet:
Coadministration of Zecyte 250mg Tablet with Venetoclax can increase the levels of Venetoclax in the body. This increases the risk or severity of side effects like bleeding problems, kidney injury, and the risk of developing serious infections.

How to manage the interaction:
Taking Zecyte 250mg Tablet with Venetoclax together can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
AbirateroneHydroxychloroquine
Severe
How does the drug interact with Zecyte 250mg Tablet:
The combined use of Zecyte 250mg Tablet and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Zecyte 250mg Tablet and Hydroxychloroquine can lead to an interaction, but it can be taken if your doctor advises. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
AbirateroneArsenic trioxide
Severe
How does the drug interact with Zecyte 250mg Tablet:
Taking Zecyte 250mg Tablet with Arsenic trioxide can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Zecyte 250mg Tablet with arsenic trioxide together can result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, or a rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to take vegetables like cauliflower, cabbage, broccoli, spinach and kale. This food slows the growth of prostate cancer and even reduces the risk of prostate cancer.
  • It is advised to consume fewer dairy products as these foods may increase the risk of prostate cancer. 
  • Physical activity helps in strengthening muscles, reduces fatigue, helps in weight loss and gives strength.
  • Maintain a healthy weight by doing regular simple exercises and yoga. 
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention. 
  • Avoid including red meat high amounts of meat in your diet. When meat is cooked, it may increase the risk of developing prostate cancer.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

ZECYTE 250MG TABLET Substitute

Substitutes safety advice
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Alcohol

Caution

Interaction of ZECYTE 250MG TABLET with alcohol is unknown. It is advisable to consult your doctor if you have concerns.

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Pregnancy

Not applicable

Not intended for women.

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Breast Feeding

Not applicable

Not intended for women.

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Driving

Caution

ZECYTE 250MG TABLET may decrease alertness or make you feel sleepy and dizzy. So, do not drive or operate heavy machinery while taking ZECYTE 250MG TABLET until your vision improves.

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Liver

Caution

ZECYTE 250MG TABLET should be used with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust the dose based on your condition.

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Kidney

Caution

ZECYTE 250MG TABLET should be used with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust the dose based on your condition.

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Children

Unsafe

ZECYTE 250MG TABLET is not recommended for use in children as the safety and efficacy of this medicine are not established.

Have a query?

FAQs

ZECYTE 250MG TABLET is used to treat Prostate Cancer.

ZECYTE 250MG TABLET contains Abiraterone acetate, which belongs to the class of androgen biosynthesis inhibitors. It works by inhibiting the production of the testosterone hormone and thus stops the growth and spread of cancer.

No, do not stop taking ZECYTE 250MG TABLET without consulting your doctor. It is recommended to take this medicine for the entire prescribed duration, even when symptoms improve or resolve.

The common side-effects of ZECYTE 250MG TABLET are nausea, dizziness, heartburn, headache, diarrhoea, muscle weakness, joint pain, confusion, hot flushes, loss of appetite, and groin pain. These side effects usually do not require any medical attention.

Take ZECYTE 250MG TABLET as advised by your doctor. However, if you forget or miss any dose of ZECYTE 250MG TABLET, take it as soon as you remember unless it is time for your next dose. But do not double the dose.

Inform your doctor if you have a pre-existing or a history of liver/kidney disease, hypoglycemia, hypokalemia, bone disorders, adrenocortical insufficiency, fluid retention and cardiovascular conditions before taking ZECYTE 250MG TABLET.

ZECYTE 250MG TABLET is not a cure for prostate cancer. However, it helps manage advanced stages by blocking testosterone production, thereby slowing the growth and progression of the cancer.

No, ZECYTE 250MG TABLET is not a chemotherapy drug. ZECYTE 250MG TABLET is a hormonal therapy that lowers testosterone levels to reduce the growth of prostate cancer.

You need to take prednisolone with ZECYTE 250MG TABLET to reduce the risk of high blood pressure, fluid retention (too much water in your body), and low potassium levels in your blood which may be caused by ZECYTE 250MG TABLET.

Yes, ZECYTE 250MG TABLET can affect the liver. Your healthcare provider will perform blood tests to check your liver function before and during treatment.

Liver function tests (investigation) should be conducted before starting ZECYTE 250MG TABLET and periodically during treatment, as advised by your healthcare provider.

ZECYTE 250MG TABLET should be taken once daily on an empty stomach, at least two hours after eating or one hour before eating. Swallow ZECYTE 250MG TABLET whole with a glass of water; do not chew, crush, or break it. Always follow the recommended dose.

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Other Info - ZEC0055

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