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compositionComposition:GENTAMICIN-80MG
prescription
Prescription Medicine
info
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Zenotic 80mg Kit is an antibiotic used in the treatment of bacterial infections of the ear, nose, throat, respiratory tract, gastrointestinal tract, biliary tract, bone and joint, skin and soft tissue. It helps by inhibiting the protein synthesis of the bacterial cell and thereby helps fight infection causing bacteria. This medicine is not effective for treating viral infections.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
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More about the Product

Composition :

GENTAMICIN-80MG

Manufacturer/Marketer :

Shreya Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Zenotic 80mg Kit

Zenotic 80mg Kit is a prescribed injectable antibiotic used to treat serious, life-threatening bacterial infections throughout the body. It is typically prescribed for severe blood, urinary tract, chest, or abdominal infections when other treatments may not be effective. Its main medical purpose is to target and destroy the bacteria causing these severe illnesses.

Because this medicine is injected directly into the body, it is usually given on a highly consistent daily schedule determined by your doctor to maintain steady levels in your blood. It is crucial to complete the entire course of treatment, even if you begin to feel better within a few days. Drinking plenty of fluids during your treatment is a highly helpful lifestyle habit that protects your body while using this medication.

Common side effects of this medication may include mild nausea, poor appetite, or irritation where the injection was given. However, you must contact your doctor immediately if you experience serious symptoms such as changes in your hearing, constant ringing in your ears, severe dizziness, or a sudden drop in how much you urinate.

Before starting treatment, talk to your doctor if you have a history of kidney disease, hearing problems, or nerve-muscle disorders like myasthenia gravis. Do not take this medicine if you have ever had a severe allergic reaction to similar injectable antibiotics.

This medicine can interact with other treatments like strong water pills or other antibiotics, which can increase the risk of kidney or hearing damage. If you are pregnant, breastfeeding, or an elderly individual, consult your doctor as your dosage and kidney health will need very close monitoring.

Uses of Zenotic 80mg Kit

Your doctor may prescribe Zenotic 80mg Kit to help manage the following conditions:

  • Severe blood infections (sepsis): It helps eliminate bacteria circulating in the bloodstream to prevent systemic organ damage.
  • Complicated urinary tract infections: It targets and clears deep-seated bacterial infections in the kidneys and bladder.
  • Chest and lung infections: It treats serious bacterial pneumonia when other standard antibiotics are not suitable.
  • Bone and joint infections: It reaches deep tissues to clear stubborn bacterial bone infections and support healing.
  • Abdominal infections: It resolves severe bacterial infections within the stomach and abdominal cavity.

Key Benefits

When used as directed as part of your treatment plan, Zenotic 80mg Kit may provide the following benefits:

  • Helps treat serious bacterial infections: Helps eliminate susceptible bacteria causing severe infections in different parts of the body.
  • Helps control the spread of infection: Helps prevent the infection from becoming worse or spreading to other organs.
  • Supports recovery from severe infections: Helps treat serious infections affecting the bloodstream, urinary tract, lungs, abdomen, bones, and joints when caused by susceptible bacteria.
  • May relieve infection-related symptoms: As the infection improves, symptoms such as fever, chills, pain, and tiredness may gradually improve.
  • Supports recovery when used with other antibiotics: For some severe infections, your doctor may prescribe this medicine together with other antibiotics to improve treatment.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Zenotic 80mg Kit will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How Zenotic 80mg Kit Works

Zenotic 80mg Kit contains gentamicin; it belongs to a class of medicines known as aminoglycoside antibiotics (a medicine used to treat bacterial infections). It works by entering bacterial cells and attaching to ribosomes (structures inside bacteria that make proteins). This prevents the bacteria from making the proteins they need to grow, survive, and multiply. As a result, the bacteria die. By killing the bacteria causing the infection, this medicine helps your body's immune system (the body's natural defence against infection) clear the infection. This medicine works only against susceptible bacterial infections. It does not treat viral infections such as the common cold or flu.
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Alcohol

Caution

Limit or avoid alcohol intake while being treated with Zenotic 80mg Kit since it may worsen side effects like dizziness.

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Pregnancy

Caution

Zenotic 80mg Kit should be cautiously administered during pregnancy since there are chances of fetal harm. Please consult your doctor before taking Zenotic 80mg Kit if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Zenotic 80mg Kit can be excreted into breast milk in small amounts when used by a nursing mother. Please consult your doctor before taking Zenotic 80mg Kit if you are breastfeeding.

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Driving

Caution

Zenotic 80mg Kit may cause side effects like dizziness or vertigo that could affect your driving ability. Do not drive or operate machinery in such cases. Drive only when you are mentally alert.

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Liver

Caution

Let your doctor know if you have any history of liver diseases before taking Zenotic 80mg Kit since it may cause abnormal liver function tests.

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Kidney

Caution

Let your doctor know if you have any history of kidney diseases or impairment before taking Zenotic 80mg Kit. Dose adjustment may be required.

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Children

Caution

Zenotic 80mg Kit should be used for children only when prescribed by a doctor. The dose may depend on the child's age and body weight.

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Heart

Caution

Zenotic 80mg Kit can be used in heart patients, but with caution. It may cause electrolyte imbalances or kidney strain, which can indirectly affect heart function, especially in those with pre-existing cardiac conditions. Always consult your doctor before use to ensure it's safe for your specific heart profile.

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Geriatrics

Caution

Zenotic 80mg Kit can be used in geriatric patients, but older adults are more susceptible to kidney damage and hearing loss. Doctors typically adjust the dose and monitor kidney function closely to ensure safe use.

What if I have taken an overdose of Zenotic 80mg Kit

If you suspect you have received too much of this medicine, seek immediate medical attention. An overdose can increase the risk of damage to your kidneys and the nerves that control your hearing and balance.

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water throughout the day (unless your doctor advises you to limit fluids) to help your kidneys safely filter and flush the medication from your system.
  • Rest and conserve energy: Allow your body plenty of physical rest to help your immune system fight off the severe infection.
  • Monitor your body's output: Pay attention to the frequency and colour of your urine, and report any sudden changes to your doctor.
  • Avoid sudden movements: If you feel slightly unsteady or dizzy during your treatment course, move slowly and avoid heavy physical activities to prevent falls.
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How Soon It Starts Working

The time required for Zenotic 80mg Kit to start to work: Zenotic 80mg Kit ideally shows its action within 30 to 60 minutes after administration. The time for which the effects of Zenotic 80mg Kit last: The effect of Zenotic 80mg Kit lasts for 6 to 8 hours.

What if you forget to take Zenotic 80mg Kit

Because this medication relies on a strict schedule to keep steady levels in your body, you must receive it consistently. If you think you have missed an injection, contact your doctor or clinic immediately for instructions. Do not double the dose to make up for a missed one.

Storage

•Store Zenotic 80mg Kit vials at controlled room temperature, safely between 20°C and 25°C (68°F to 77°F). •Do not freeze the medicine, and keep it protected from direct sunlight, moisture, and excessive heat.

Drug Warnings

  • Complete the full course: Continue receiving this medicine for the full duration prescribed, even if you start feeling better, unless your doctor tells you to stop.
  • Stay well hydrated: Drink plenty of fluids during treatment, unless your doctor has advised you to limit your fluid intake. This helps support normal kidney function.
  • Watch for hearing changes: Consult your doctor right away if you notice ringing in your ears, hearing loss, dizziness, or problems with balance during treatment.
  • Report kidney-related symptoms: Consult your doctor right away if you notice a decrease in the amount of urine you pass, swelling of your feet or ankles, or unusual tiredness, as these may be signs of kidney problems.
  • Attend follow-up appointments: Keep all scheduled appointments for blood tests so your doctor can monitor your kidney function and, if needed, the level of gentamicin in your blood to help ensure safe treatment.
  • Tell your doctor about other medicines: Inform your doctor about all medicines you are taking, especially medicines that may affect the kidneys or hearing, before and during treatment.
  • Seek help for severe diarrhoea: Consult your doctor right away if you develop severe or persistent diarrhoea during or after treatment, as this could be a sign of a serious bowel infection associated with antibiotic use.
  • Tell your healthcare team about muscle disorders: Before treatment, inform your doctor if you have myasthenia gravis (a condition that causes muscle weakness) or other neuromuscular disorders, as gentamicin may worsen muscle weakness.

Drug-Drug Interactions

verifiedApollotooltip
  • Water pills (loop diuretics like furosemide): May significantly increase the risk of hearing damage and kidney issues when used together.
  • Other strong antibiotics (such as vancomycin or cephalosporins): Can place extra strain on your kidneys and increase the risk of kidney damage.
  • Muscle relaxants (used during surgery): This medicine may prolong or strengthen the effects of muscle relaxants, which can affect your breathing.
GentamicinTenofovir alafenamide
Severe
GentamicinRocuronium bromide
Severe

Drug-Drug Interactions

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GentamicinTenofovir alafenamide
Severe
How does the drug interact with Zenotic 80mg Kit:
Co-administration of Tenofovir alafenamide may cause kidney problems and combining it Zenotic 80mg Kit may increase that risk.

How to manage the interaction:
Although there is a possible interaction, Zenotic 80mg Kit can be taken with tenofovir alafenamide if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.
GentamicinRocuronium bromide
Severe
How does the drug interact with Zenotic 80mg Kit:
When Rocuronium is used with Zenotic 80mg Kit, it can make the treatment more effective.

How to manage the interaction:
Co-administration of Rocuronium bromide with Zenotic 80mg Kit can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
GentamicinMetrizamide
Severe
How does the drug interact with Zenotic 80mg Kit:
Co-administration of Metrizamide with Zenotic 80mg Kit may increase the risk of kidney problems.

How to manage the interaction:
Taking Zenotic 80mg Kit with Metrizamide together can possibly result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let a doctor know right away. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble with your muscles, balance, or heart rhythm. Do not stop using any medications without a doctor's advice.
GentamicinMagnesium sulfate
Severe
How does the drug interact with Zenotic 80mg Kit:
Co-administration of Magnesium sulfate with Zenotic 80mg Kit can increase the risk of muscle weakness.

How to manage the interaction:
Although there is a possible interaction between Magnesium sulfate and Zenotic 80mg Kit, you can take these medicines together if prescribed by a doctor. However, consult a doctor if you experience muscle weakness and breathing difficulties. Do not stop using any medications without talking to a doctor.
GentamicinHuman immunoglobulin
Severe
How does the drug interact with Zenotic 80mg Kit:
Co-administration of Human immunoglobulin with Zenotic 80mg Kit may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Zenotic 80mg Kit together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
GentamicinMannitol
Severe
How does the drug interact with Zenotic 80mg Kit:
Co-administration of Mannitol with Zenotic 80mg Kit can increase the risk of kidney damage.

How to manage the interaction:
There may be a possibility of interaction between Zenotic 80mg Kit and Mannitol, but it can be taken if prescribed by a doctor. If you're having problems like hearing loss, ringing in your ears, feeling dizzy, or having kidney issues, it's important to let your doctor know right away. They may be able to recommend other options for you that won't cause these problems. Do not stop using any medications without a doctor's advice.
GentamicinTemsirolimus
Severe
How does the drug interact with Zenotic 80mg Kit:
Co-administration of Zenotic 80mg Kit and Temsirolimus may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Zenotic 80mg Kit with Temsirolimus can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes like peeing more or less than usual, it's a good idea to let your doctor know right away. Some signs to watch out for include gaining weight quickly, feeling bloated, having trouble breathing, or feeling sick to your stomach. Other symptoms to be aware of are not feeling hungry, losing weight, swelling, muscle cramps, feeling weak or dizzy, feeling confused, or having an irregular heartbeat. Do not stop using any medications without a doctor's advice.
GentamicinColistin
Severe
How does the drug interact with Zenotic 80mg Kit:
Co-administration of Colistin with Zenotic 80mg Kit can increase the levels and risk of Colistin side effects.

How to manage the interaction:
Although there is a possible interaction between Colistin and Zenotic 80mg Kit, you can take these medicines together if prescribed by your doctor. However, if you experience weight gain or loss suddenly, muscle pain, dizziness, or palpitations, call your doctor right away. Do not stop using any medications without a doctor's advice.
GentamicinPipecuronium bromide
Severe
How does the drug interact with Zenotic 80mg Kit:
Co-administration of Pipecuronium bromide with Zenotic 80mg Kit may increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Zenotic 80mg Kit and Pipecuronium bromide, but it can be taken if prescribed by a doctor. If you have trouble breathing or feel like you can't breathe at all, it's important to contact your doctor right away. This is especially true if you're having difficulty breathing for a long time. Do not stop using any medications without a doctor's advice.
GentamicinClindamycin
Severe
How does the drug interact with Zenotic 80mg Kit:
Co-administration of of clindamycin with Zenotic 80mg Kit may increase the risk of kidney and/or nerve damage.

How to manage the interaction:
Although there is a possible interaction, clindamycin can be taken with Zenotic 80mg Kit if prescribed by the doctor. Consult the prescriber if you experience signs and symptoms of kidney damage such as sudden weight gain or weight loss, nausea, vomiting, fluid retention, loss of appetite, increased or decreased urination, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. If you develop diarrhea or vomiting during treatment with these medications, drink plenty of fluids to prevent dehydration, as dehydration may also harm the kidney.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Zenotic 80mg Kit when used as directed.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Zenotic 80mg Kit belongs to the class of 'antibiotics', primarily used to treat serious bacterial infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness.
Zenotic 80mg Kit is an antibiotic that treats bacterial infections. It works by inhibiting bacterial protein synthesis, which retards bacterial growth.
Zenotic 80mg Kit should be used with proper caution and doctor consultation if you have any allergic reactions to medicines, liver/kidney problems, cystic fibrosis, hearing problems, low blood minerals/electrolyte imbalance, myasthenia gravis (muscular weakness), and Parkinson's disease.
Zenotic 80mg Kit can affect the live vaccines like typhoid vaccine and decrease its effectiveness. Please consult a doctor if you are undergoing any vaccinations.
Zenotic 80mg Kit may cause abnormal liver function tests as one of its side effects. It may increase the levels of liver enzymes and blood bilirubin. Please consult your doctor before starting Zenotic 80mg Kit if you have any history of liver problems.
Diarrhoea can be a side-effect of Zenotic 80mg Kit. Clostridium difficile-associated diarrhoea (CDAD) is also reported during usage of antibiotics like Zenotic 80mg Kit. Therefore, when the patient has diarrhoea, undergoing an examination is advised to rule out the chances of CDAD following Zenotic 80mg Kit therapy.
This medicine is injected either directly into a large muscle or given slowly into a vein through an intravenous infusion. It is typically administered by a trained healthcare professional. Talk to your doctor if you have questions about how your injections are given.
Yes, this medication can affect kidney function, especially if it is used for a long time or in high doses. Your doctor will monitor your kidney health with regular blood tests during your treatment. Talk to your doctor if you notice you are urinating less than usual.
Ringing in your ears, hearing loss, or dizziness are serious signs that the medicine may be affecting your inner ear nerves. You must contact your doctor immediately if you notice these changes. Talk to your doctor to see if your treatment plan needs to be adjusted.
This medicine is generally not recommended during pregnancy because it can cause harm, including permanent hearing loss, to the unborn baby. It is typically reserved for life-threatening infections when other options cannot be used. Talk to your doctor to discuss the risks and benefits.
Regular blood tests are necessary to measure the exact amount of the medicine in your blood and to check how well your kidneys are working. This helps your doctor keep the dose in a safe and effective range. Talk to your doctor or pharmacist about your blood monitoring schedule.
While alcohol does not directly interact with this medicine, it can cause dehydration, which increases the strain on your kidneys. It is highly recommended to avoid alcohol and focus on staying well-hydrated during your recovery. Talk to your doctor for personalised advice.
No, you must complete the exact course prescribed by your doctor, even if you feel completely recovered. Stopping an antibiotic too early can allow the strongest bacteria to survive, multiply, and become resistant to treatment. Talk to your doctor before making any changes.

Disclaimer

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Reference

  1. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Gentamicin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. ScienceDirect ScienceDirect. [Accessed on 31 Mar. 2019]Check here
  4. PubChem PubChem. [Accessed on 31 Mar. 2019]Check here
  5. PubChem Compound Summary for CID 5311051, Clobetasol. National Center for Biotechnology Information. June 2022. [Accessed on 27th June 2022]Check here
  6. Bruno J. Chaves; Prasanna Tadi. Gentamicin. StatPearls [Internet]. StatPearls Publishing. May 2022. [Accessed on 27th June 2022]Check here
  7. Glaxo Operations UK Limited. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 27th June 2022]Check here

Country of origin

India
Other Info - ZE17712
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