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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CARBAMAZEPINE-300MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Zepcar 300mg Tablet CR

Zepcar 300mg Tablet CR is a prescription medication primarily used to control and prevent various types of seizures in people with epilepsy. It is also prescribed to treat severe nerve pain in the face, known as trigeminal neuralgia, and to help stabilise moods in certain patients with bipolar disorder. This medicine works on the nervous system to calm overactive nerve signals.

To get the best results, you must take Zepcar 300mg Tablet CR regularly and exactly as prescribed by your doctor. It can be taken with or without food, but taking it with a meal may help if it upsets your stomach. Along with taking your medicine, maintaining a regular sleep schedule and avoiding specific dietary triggers can significantly support your treatment.

While taking Zepcar 300mg Tablet CR, you may experience mild side effects like drowsiness or dizziness, which often improve as your body adjusts. However, it is vital to contact your doctor immediately if you develop any severe reactions, especially a skin rash, fever, or unusual bruising.

Talk to your doctor before starting this medicine if you have a history of heart, liver, or kidney problems. Do not take this if you have a history of bone marrow depression, a known hypersensitivity to carbamazepine, tricyclic compounds, or structurally related medicines, or if you have taken a monoamine oxidase inhibitor (MAOI) within the last 14 days.

This medicine can interact with several other drugs, including hormonal birth control, making them less effective. It is also important to avoid alcohol while taking Zepcar 300mg Tablet CR because it can worsen drowsiness and increase the risk of seizures. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to discuss the risks and benefits.

Uses of Zepcar 300mg Tablet CR

Zepcar 300mg Tablet CR is used to treat the following conditions: 

  • Epilepsy: Zepcar 300mg Tablet CR helps control and prevent various types of seizures by stabilising overactive electrical activity in the brain.
  • Trigeminal Neuralgia: Zepcar 300mg Tablet CR relieves intense, stabbing facial nerve pain by calming hyperactive nerve pathways in the face.
  • Bipolar Disorder: Zepcar 300mg Tablet CR helps stabilise mood swings and manage manic episodes in certain patients when other treatments are not suitable.
     

Key Benefits

Zepcar 300mg Tablet CR helps control abnormal electrical activity in the brain and nerves, making it effective for managing seizures, certain nerve pain conditions, and some mood disorders.

  • Controls Seizures: Helps reduce the frequency and severity of seizures, supporting better day-to-day functioning and safety.
  • Relieves Nerve Pain: Provides relief from intense nerve-related pain, such as trigeminal neuralgia, making activities like eating, speaking, and facial movement more comfortable.
  • Stabilises Nerve Activity: Helps regulate abnormal nerve signals, reducing symptoms caused by nerve overactivity.
  • Supports Mood Stability: May help promote emotional balance and support mood stabilisation in certain conditions.
  • Improves Quality of Life: Better symptom control can help increase independence, comfort, and confidence in daily activities.
     

Directions for Use

Always take Zepcar 300mg Tablet CR exactly as your doctor has instructed. Follow these steps for safe use:

  • Take this medicine by mouth, usually with a glass of water.
  • You can take it with or without food, but taking it with a meal can help prevent stomach upset.
  • If you are taking extended-release tablets, swallow them whole. Do not crush, chew, or break them, as this can release all the medicine at once and increase side effects.
  • Never stop taking this medicine suddenly, even if you feel completely fine, as this can cause your seizures or pain to return suddenly.

If you have any questions about how to take your dose, talk to your doctor or pharmacist.
 

How Zepcar 300mg Tablet CR Works

Zepcar 300mg Tablet CR contains carbamazepine, which belongs to a group of medicines called anticonvulsants. It works by targeting the sodium channels on the surface of nerve cells in your brain and spinal cord. When these nerve cells become overactive, they send rapid, repetitive electrical signals that can trigger seizures or intense nerve pain. By temporarily blocking these sodium channels, Zepcar 300mg Tablet CR slows down the flow of electrical impulses. This helps stabilise the nerve membranes, preventing the abnormal, uncontrolled electrical storms in the brain that cause seizures and calming the hyperactive nerves responsible for chronic pain.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zepcar 300mg Tablet CR as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking Zepcar 300mg Tablet CR if you are pregnant unless prescribed by a doctor, as it could lead to serious birth defects. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

It is safe to take Zepcar 300mg Tablet CR while breastfeeding. However, consult your doctor immediately if you think that the baby is having side effects like excessive sleepiness, skin reactions or yellowing of skin or eyes.

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Driving

Unsafe

Zepcar 300mg Tablet CR causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Consult your doctor

Zepcar 300mg Tablet CR can be given to children above 6 years if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

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Heart

Caution

Zepcar 300mg Tablet CR can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Zepcar 300mg Tablet CR to geriatric patients. Your doctor will prescribe Zepcar 300mg Tablet CR if the benefits outweigh the risks.

What if I have taken an overdose of Zepcar 300mg Tablet CR

Do not take more than the prescribed dose of Zepcar 300mg Tablet CR as it may cause an overdose. The symptoms of overdose include dizziness, sleepiness, difficulty talking, nausea or vomiting, stomach pain, blurred vision, confusion or normal behaviour changes. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Avoid grapefruit products: Do not eat grapefruit or drink grapefruit juice while taking Zepcar 300mg Tablet CR, as it can increase the levels of the medicine in your blood to dangerous levels.
  • Avoid alcohol: Do not drink alcohol. It can greatly increase drowsiness, impair your coordination, and increase the risk of having a seizure.
  • Prioritise consistent sleep: Ensure you get a consistent, adequate amount of sleep every night, as sleep deprivation is a known trigger for seizures.
  • Use alternative birth control: If you use hormonal contraceptives (like pills, patches, or implants), use a reliable backup barrier method (such as condoms) because Zepcar 300mg Tablet CR can make hormonal birth control less effective.

Have a query?

How Soon It Starts Working

The time required for Zepcar 300mg Tablet CR to start to work: Zepcar 300mg Tablet CR ideally shows its action within 4 hours after administration.

The time for which the effects of Zepcar 300mg Tablet CR last: The effect of Zepcar 300mg Tablet CR lasts for 2 to 3 days.

What if you forget to take Zepcar 300mg Tablet CR

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

Store Zepcar 300mg Tablet CR at room temperature, ideally between 20°C and 25°C (68°F to 77°F). Keep the medication in its original container to protect it from light and moisture.

Drug Warnings

  • Do Not Stop Suddenly: Never stop taking Zepcar 300mg Tablet CR without medical advice, as sudden discontinuation may trigger seizures or worsen symptoms.
  • Protect Your Skin from Sunlight: Wear sunscreen and protective clothing when outdoors, as this medicine may increase sensitivity to sunlight.
  • Monitor Mood Changes: Contact your doctor immediately if you notice new or worsening depression, anxiety, mood changes, or unusual thoughts.
  • Attend Regular Blood Tests: Keep all scheduled appointments so your doctor can monitor your blood cell counts and liver function during treatment.
  • Use Caution During Activities: Avoid driving, operating machinery, or performing tasks requiring alertness until you know how Zepcar 300mg Tablet CR affects you.

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact with Zepcar 300mg Tablet CR: 

  • Hormonal Contraceptives: Zepcar 300mg Tablet CR can speed up the breakdown of hormonal birth control, making it less effective and increasing the risk of unplanned pregnancy.
  • Blood Thinners: It can reduce the effectiveness of blood thinners such as warfarin, requiring close monitoring and possible dose adjustments.
  • MAO Inhibitors: Do not take this medicine if you have taken a monoamine oxidase inhibitor (MAOI) within the past 14 days, as serious reactions may occur.
  • Other Antiepileptic Medicines: Medicines such as phenytoin, valproate, lamotrigine, and other anti-seizure treatments may affect Zepcar 300mg Tablet CR levels or have their own levels altered when used together. Your doctor may need to monitor treatment closely and adjust doses.
  • Certain Antibiotics and Antifungals: Medicines such as erythromycin, clarithromycin, or ketoconazole may increase Zepcar 300mg Tablet CR levels in the body and raise the risk of side effects.
  • Other Medications: Several prescription, over-the-counter, and herbal medicines can interact with Zepcar 300mg Tablet CR. Always inform your doctor about all medicines and supplements you are taking.

Drug-Food Interactions

Certain foods and beverages may affect how Zepcar 300mg Tablet CR works or increase the risk of side effects:

  • Grapefruit and Grapefruit Juice: Grapefruit products may affect how your body processes Zepcar 300mg Tablet CR and could increase the risk of side effects in some people. The clinical significance of this interaction may vary, so consult your doctor or pharmacist about grapefruit consumption during treatment.

Drug-Disease Interactions

Inform your doctor if you have any of the following conditions before taking Zepcar 300mg Tablet CR, as dose adjustments or additional monitoring may be required: 

  • Heart Conditions: This medicine should be used with extreme caution if you have a history of heart block or other heart rhythm disorders, as it can worsen these conditions.
  • Bone Marrow Suppression: Do not take this medicine if you have a history of bone marrow depression, as it can further lower your white blood cell, red blood cell, or platelet counts.
  • Liver and Kidney Disease: If you have liver or kidney damage, your body may process this medicine more slowly, requiring careful dose adjustments and monitoring.
     

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

FAQs

Zepcar 300mg Tablet CR is used to treat epilepsy (fits) and trigeminal neuralgia (pain in the face nerves).

Zepcar 300mg Tablet CR decreases the brain's excessive and abnormal nerve activity by blocking sodium currents in your brain and body. This reduces abnormal electrical activity between your nerve cells.

Zepcar 300mg Tablet CR may cause hyponatremia (low sodium levels in the blood). This could lead to confusion, reduced concentration, vision problems, nausea, vomiting or worsening of seizures. Regular monitoring of sodium levels is advised while taking Zepcar 300mg Tablet CR. Consult your doctor if you experience these symptoms.

Dry mouth could be a side effect of Zepcar 300mg Tablet CR. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

No, it is not an analgesic medication. It is an anticonvulsant or anti-epileptic used to treat epilepsy (fits) and trigeminal neuralgia (pain in the face's nerves).

Before using Zepcar 300mg Tablet CR, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimize side effects.

Long-term usage of Zepcar 300mg Tablet CR may result in osteoporosis and osteopenia. Your doctor may perform specific tests to assess your bone strength. A healthy diet and regular exercise can also help your bones stay strong.

Consumption of alcohol and drinking grapefruit juice or eating grapefruit should be avoided. The risk of sleepiness and dizziness may be increased if you drink alcohol while taking carbamazepine. Grapefruit may increase the effects of Zepcar 300mg Tablet CR by increasing its levels in the body.

Do not stop taking Zepcar 300mg Tablet CR unless your doctor tells you to. If you take carbamazepine for epilepsy, you may get seizures after you stop using it. To avoid withdrawal seizures, gradually reduce your carbamazepine dose as suggested by your doctor. Suppose you are taking it for bipolar disorder or nerve pain. In that case, your condition may worsen temporarily after you stop using it.

Watch for early warning signs of suicidal thoughts and actions, such as changes in mood or withdrawal from others. Increased anxiety or irritability, changes in sleep or self-care habits, and giving away belongings or talking about death can also be indicators. Be alert to self-harm or reckless behaviour and feelings of hopelessness or being trapped. If you observe these signs, express empathy and care by asking open-ended inquiries and attentively listening. Take all suicide warnings seriously and seek help, as early intervention can make a big difference.

Weight gain is one of the more typical adverse effects of Zepcar 300mg Tablet CR. However, this is not happening for everyone, and it is not indicated for use in weight gain. Follow a nutritious diet and exercise regularly to maintain a healthy weight.

Several common seizure medicines, including Zepcar 300mg Tablet CR, have been shown to affect hormone levels. In men, Zepcar 300mg Tablet CR may reduce the level of free testosterone (the primary male hormone). Low levels of testosterone are linked to decreased sexual desire.

If you have nerve pain, once the pain has gone, you will need to take Zepcar 300mg Tablet CR for several months to stop it coming back.

The common side effects of Zepcar 300mg Tablet CR are usually mild and disappear. If they do not go away, there are things you can do to help cope with the specific lifestyle changes. For example, if you're feeling or being sick, try having small, frequent sips of water or squash to avoid dehydration. Stick to simple meals and do not eat rich or spicy food. To manage headaches, make sure you rest and drink plenty of fluids. Try not to drink too much alcohol. To control Dry mouth, try chewing sugar-free gum or sucking sugar-free sweets.

If you want to switch medicines, it is very important to follow your doctor's advice. Switching from carbamazepine to a different medicine will be different for each person. Do not switch medications on your own unless recommended by the doctor.

You can take Zepcar 300mg Tablet CR as usual before and after surgery. However, because it may reduce the effects of some muscle relaxants, these may need to be increased. Tell your doctor you are on carbamazepine if you need surgery.

When you first start taking Zepcar 300mg Tablet CR, you may feel sleepy, tired, or dizzy. This may also happen if your dose has increased. If you're affected, do not drive, ride a bike, or operate machinery until you feel better.

Epilepsy is a common neurological disorder that produces recurrent seizures. Seizures are bursts of electrical activity in the brain that briefly impair its function.

Living with seizures requires some adjustments, but it's possible to manage and cope. Begin by learning about your disease, available treatment choices, and associated triggers. Take your medication exactly as directed, and try to avoid frequent triggers including stress, lack of sleep, and excessive alcohol intake. Maintaining a seizure diary might also help you discover patterns and be prepared. Additionally, take simple safety precautions like showering instead of bathing and wearing a helmet when biking. Build a support network of friends, family, and healthcare professionals, and don't hesitate to reach out when you need help. Finally, prioritize self-care by managing stress, staying active, and getting enough rest. With the right mindset and strategies, you can lead an entire and active life despite living with seizures.

No, you should avoid alcohol while taking Zepcar 300mg Tablet CR. Alcohol can increase side effects like extreme drowsiness and dizziness, and it may also trigger seizures. Talk to your doctor if you have concerns about avoiding alcohol.

If you notice a skin rash, contact your doctor immediately. In rare cases, Zepcar 300mg Tablet CR can cause severe, life-threatening skin reactions, especially during the first few months of treatment. Talk to your doctor before taking any more doses.

Yes, Zepcar 300mg Tablet CR can make hormonal birth control (including pills, patches, rings, and implants) less effective. It is recommended to use an additional, non-hormonal barrier method of contraception, such as condoms. Talk to your doctor to discuss the best birth control options for you.

Zepcar 300mg Tablet CR may increase the risk of birth defects, including neural tube defects, when taken during pregnancy. However, uncontrolled seizures can also pose serious risks to both the mother and baby. If you are pregnant, planning a pregnancy, or could become pregnant, speak with your doctor before making any changes to treatment. Your doctor may recommend folic acid supplementation before conception and during pregnancy to help reduce certain risks. Do not stop taking Zepcar 300mg Tablet CR without medical advice.

It can take several days or even a few weeks for Zepcar 300mg Tablet CR to reach its full effect in controlling seizures or nerve pain. Your doctor may start with a low dose and gradually increase it. Talk to your doctor if you do not feel any improvement after a few weeks.

Regular tablets should be swallowed whole with water. If you are taking extended-release or controlled-release tablets, you must never crush or chew them, as this can release the entire dose too quickly. Talk to your doctor or pharmacist if you have trouble swallowing tablets.

Your doctor will schedule regular blood tests to monitor your blood cell counts, liver function, and the levels of the medicine in your blood. This helps ensure the medicine is working safely and effectively. Talk to your doctor about how often you will need these tests.

Zepcar 300mg Tablet CR can increase its own metabolism during the first few weeks of treatment, which may reduce medicine levels in the body. If your seizures, nerve pain, or other symptoms worsen after initially improving, contact your doctor. They may need to adjust your dose or monitor your medicine levels.

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Country of origin

India
Other Info - ZE98888
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