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  3. Zeropress 5mg Tablet ER

Zeropress 5mg Tablet ER, Pack of 1 Tablet
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zeropress 5mg Tablet ER is used to treat hypertension (high blood pressure). In addition to this, it is also used to treat mild prostate gland enlargement in men (known as Benign Prostate Hyperplasia), heart failure, and painful cold fingers (Raynaud’s Disease). It contains Prazosin, which acts by relaxing the blood vessels and muscles around the bladder and prostate gland. Sometimes, this medicine may cause common side effects such as drowsiness, headache, weakness, dizziness, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components and about all the medications you are taking and pre-existing medical conditions.

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Synonym :

PRAZOSIN HYDROCHLORIDE

Composition :

PRAZOSIN-5MG

Manufacturer/Marketer :

Albus Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Zeropress 5mg Tablet ER

Zeropress 5mg Tablet ER is used to treat hypertension (high blood pressure). It may also be used to treat mild prostate gland enlargement in men (known as Benign Prostate Hyperplasia), painful cold fingers (Raynaud’s Disease) and heart failure.

Zeropress 5mg Tablet ER contains Prazosin, an alpha-blocker, which works by relaxing the blood vessels and improving blood flow. In patients with an enlarged prostate, it relaxes the muscles around the bladder and prostate so that urine is passed more easily.

The common side effects of Zeropress 5mg Tablet ER are drowsiness, headache, weakness, dizziness, nausea, and dry mouth. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not take Zeropress 5mg Tablet ER if you are allergic to any of its components. Inform your doctor if you are pregnant or breastfeeding. Let your doctor know about your health conditions and medications to prevent any potential interactions.

Uses of Zeropress 5mg Tablet ER

Zeropress 5mg Tablet ER is used in the treatment of high blood pressure (hypertension), benign prostate hyperplasia, and cold finger syndrome (Raynaud's disease). The detailed uses of Zeropress 5mg Tablet ER are as follows:
• Hypertension Management: Zeropress 5mg Tablet ER is primarily used to treat high blood pressure by relaxing blood vessels, which helps lower the pressure against the walls of the arteries.
• Heart Failure Treatment: Zeropress 5mg Tablet ER may be used in conjunction with other medications to manage symptoms of heart failure by reducing the workload on the heart.
• Benign Prostatic Hyperplasia (BPH): Zeropress 5mg Tablet ER can help relieve urinary symptoms associated with BPH by relaxing muscles in the prostate and bladder.
• Raynaud’s Phenomenon: Zeropress 5mg Tablet ER might be used to alleviate symptoms of Raynaud’s phenomenon by improving blood flow to the extremities in response to cold or stress.

Directions for Use

  • Zeropress 5mg Tablet ER can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Zeropress 5mg Tablet ER as a whole with a glass of water.
  • Do not chew, crush or break it.

Medicinal Benefits

  • Zeropress 5mg Tablet ER is primarily used to treat high blood pressure (hypertension) by relaxing blood vessels, allowing blood to flow more easily. It can be used alone or in combination with other antihypertensive medications.
  • In patients with heart failure, Zeropress 5mg Tablet ER relaxes the main blood vessels of the heart, making it easier for the heart to pump blood. It is typically used when other treatments are no longer effective or have failed.
  • Zeropress 5mg Tablet ER may also be used to treat Raynaud’s Disease by relaxing blood vessels in the hands, improving blood flow to the fingers. This helps prevent coldness, pain, and stiffness.
  • In men with enlargement of the prostate gland (benign prostatic hyperplasia), Zeropress 5mg Tablet ER helps relieve urinary symptoms such as difficulty or frequent urination. It works by relaxing the muscles around the bladder and prostate, making it easier to pass urine.

How Zeropress 5mg Tablet ER Works

Zeropress 5mg Tablet ER contains Prazosin, which lowers blood pressure by relaxing the blood vessels, reducing the heart's workload, and making the heart more efficient at pumping blood throughout the body. In patients with Raynaud’s Disease, Zeropress 5mg Tablet ER relaxes blood vessels in the hands, improving blood flow to the fingers. In men with enlargement of the prostate gland, Zeropress 5mg Tablet ER works by relaxing the muscles around the bladder and prostate, making it easier to pass urine.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zeropress 5mg Tablet ER
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

What if I have taken an overdose of Zeropress 5mg Tablet ER

Do not take more than the prescribed dose of Zeropress 5mg Tablet ER as it may cause an overdose. The symptoms of overdose include lightheadedness, dizziness, fainting, drowsiness or decreased reflexes. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Do not take Zeropress 5mg Tablet ER if you are allergic to prazosin, or any similar drugs (known as quinazoline drugs) or any of the other ingredients of this medicine.
  • Inform your doctor if you have heart failure, liver or kidney disease, prolonged erection of the penis, cataracts, or low blood pressure.
  • Consult your doctor before taking Zeropress 5mg Tablet ER if you are pregnant, plan to become pregnant or are breastfeeding.
  • Zeropress 5mg Tablet ER may cause dizziness and drowsiness. Therefore, drive or operate machinery only if you are alert.
  • Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
  • Let your doctor know if you have any pre-existing medical conditions or if you are taking any other medicines, including supplements or herbal products.

Drug-Drug Interactions

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PrazosinTizanidine
Severe
PrazosinSodium oxybate
Severe

Drug-Drug Interactions

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PrazosinTizanidine
Severe
How does the drug interact with Zeropress 5mg Tablet ER:
Taking Tizanidine and Zeropress 5mg Tablet ER together may have additive effects in lowering your blood pressure.

How to manage the interaction:
Taking tizanidine and Zeropress 5mg Tablet ER together can possibly result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor immediately if you experience headaches, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. It is advised not to drive or use any hazardous machinery. Do not stop using any medications without a doctor's advice.
PrazosinSodium oxybate
Severe
How does the drug interact with Zeropress 5mg Tablet ER:
Taking Zeropress 5mg Tablet ER and Sodium oxybate together can increase the risk of side effects.

How to manage the interaction:
Although taking Zeropress 5mg Tablet ER and sodium oxybate together can evidently cause an interaction, it can be taken if your doctor has suggested it. Consult your doctor immediately if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking or judgement. It is advised not to drive or use any hazardous machinery. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mmHg.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily, and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oils like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Zeropress 5mg Tablet ER Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol and Zeropress 5mg Tablet ER to avoid unpleasant side effects like lowering blood pressure (hypotension).

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Pregnancy

Caution

Zeropress 5mg Tablet ER belongs to the pregnancy category C medicine. There is limited evidence regarding the use of Zeropress 5mg Tablet ER and it is generally not preferred as the initial treatment of hypertension in pregnancy. It is best to consult your doctor if you have high blood pressure during pregnancy.

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Breast Feeding

Caution

Use of Zeropress 5mg Tablet ER during breastfeeding has not been shown to cause any harmful effects in breastfed babies. If you are a nursing mother, it is best to consult your Obstetrician regarding the use of Zeropress 5mg Tablet ER.

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Driving

Caution

Drive with caution, Zeropress 5mg Tablet ER usually causes drowsiness and affects driving ability.

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Liver

Caution

Zeropress 5mg Tablet ER to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Kidney

Safe if prescribed

Zeropress 5mg Tablet ER is generally safe for patients with kidney diseases, and dose adjustment is generally not required. However, your doctor will decide the appropriate dosage strength depending on the severity of your condition.

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Children

Safe if prescribed

Zeropress 5mg Tablet ER can be given safely to children aged 6-12 years provided a child specialist has prescribed the dose. Zeropress 5mg Tablet ER should not be given to the children without consulting a child specialist.

Have a query?

FAQs

Zeropress 5mg Tablet ER is used to treat high blood pressure (hypertension), Benign Prostatic Hyperplasia, and Cold Finger Syndrome (Raynaud's disease).

Zeropress 5mg Tablet ER contains Prazosin, an alpha-blocker that acts by relaxing and widening the constricted blood vessels. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it reduces high blood pressure and reduces the chances of a future heart attack or stroke.

No, do not discontinue Zeropress 5mg Tablet ER on your own. To treat your condition effectively, keep taking Zeropress 5mg Tablet ER for the prescribed duration.

In case, you have missed a dose of Zeropress 5mg Tablet ER, you are advised to take it as soon as you remember. However, if it is time for you to take your next dose, then do not take both doses together. Take only one dose; taking a double dose of Zeropress 5mg Tablet ER will lead to low blood pressure.

Zeropress 5mg Tablet ER can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are lifelong, and one should not abruptly discontinue it without discussing it with a doctor.

Yes, Zeropress 5mg Tablet ER may cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Zeropress 5mg Tablet ER. In case you feel dizzy or light-headed, it is advised to rest for some time until you feel better.

Zeropress 5mg Tablet ER may cause priapism (prolonged erections) sometimes. If you have an erection that lasts more than four hours, inform your doctor and seek emergency medical help, as if not treated, it can lead to tissue scarring or erectile dysfunction.

Zeropress 5mg Tablet ER can cause nasal congestion due to dilation of vessels in the nasal mucosa.

Zeropress 5mg Tablet ER is not a sleeping pill. It is used to lower blood pressure in patients with hypertension.

Zeropress 5mg Tablet ER cannot get you high as it doesn’t have the potential of abuse or dependence.

Though prazosin may help with anxiety, especially related to chronic PTSD (Post-Traumatic Stress Disorder), it is not used for anxiety.

Zeropress 5mg Tablet ER should be swallowed as a whole with water. It can be taken before or after food and drinks.

Zeropress 5mg Tablet ER might cause dizziness or light-headedness, which may be caused by low blood pressure upon sitting or standing up quickly. To prevent this, avoid standing or sitting up quickly. Lie down and try getting up slowly after you feel better.

Zeropress 5mg Tablet ER belongs to the class of drugs called alpha-blockers. It relaxes the blood vessels and helps treat high blood pressure.

Side effects of Zeropress 5mg Tablet ER are drowsiness, headache, weakness, dizziness, nausea, and feeling exhausted. If the side effects are persistent, reach out to your doctor.

Country of origin

India
Other Info - ZE25035

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 16, 2025 | 2:19 PM IST

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Reference

  1. https://medlineplus.gov/druginfo/meds/a682245.html
  2. https://www.healthline.com/health/prazosin-oral-capsule
  3. https://www.drugs.com/mtm/prazosin.html
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