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compositionComposition:OXACEPROL-200MG
prescription
Prescription Medicine
info
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ZEXTRA 200MG CAPSULE is used to treat osteoarthritis. It contains Oxaceprol which works by inhibiting the accumulation of white blood cells in the affected area or joints. In some cases, this medicine may cause side effects such as stomach pain, nausea, vomiting, diarrhoea, constipation, bloating, indigestion, dizziness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

OXACEPROL-200MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About ZEXTRA 200MG CAPSULE

ZEXTRA 200MG CAPSULE is prescribed to help manage joint pain and reduce inflammation. It is primarily used to treat chronic joint conditions like osteoarthritis, helping to ease stiffness and improve movement.

For the best results, you must take ZEXTRA 200MG CAPSULE regularly and consistently exactly as your doctor prescribes. It is typically taken with food to help prevent stomach upset. Combining this medication with joint-friendly exercises and maintaining a healthy weight can significantly improve your mobility. ZEXTRA 200MG CAPSULE may not be suitable for everyone. Your doctor will decide whether it is the right treatment for you based on your symptoms, medical history, and response to treatment, particularly if long-term therapy is being considered.

While taking ZEXTRA 200MG CAPSULE, you may experience some mild side effects such as nausea or an upset stomach. However, if you notice severe skin rashes, swelling, or difficulty breathing, stop taking the medication and consult your doctor immediately.

Before starting this medicine, tell your doctor if you have a history of stomach ulcers, kidney problems, or liver issues. Do not take this medicine if you have severe renal impairment (severe kidney disease) unless your doctor specifically advises otherwise. Your healthcare provider will assess whether ZEXTRA 200MG CAPSULE is suitable for you based on your kidney function and overall medical condition. Do not take this medicine if you are allergic to ZEXTRA 200MG CAPSULE or any of its ingredients.

Some medicines, such as blood thinners, can interact with ZEXTRA 200MG CAPSULE and increase your risk of bleeding. Avoid drinking alcohol while on this medicine, as it can worsen stomach irritation. If you are pregnant, breastfeeding, or are an elderly individual, talk to your doctor or pharmacist before using this medicine.
 

Uses of ZEXTRA 200MG CAPSULE

Here are the main joint conditions where ZEXTRA 200MG CAPSULE is used to reduce inflammation, relieve pain, and improve mobility:

  • Osteoarthritis: ZEXTRA 200MG CAPSULE helps by targeting the painful swelling in weight-bearing joints like knees and hips, making daily activities easier.
  • Other degenerative joint conditions: Your doctor may occasionally prescribe ZEXTRA 200MG CAPSULE for certain chronic degenerative joint conditions when considered appropriate based on your symptoms and medical history.  
  • Other painful joint disorders: It provides relief from long-term wear-and-tear joint pain by stopping inflammatory processes in the joint tissues.
     

Key Benefits

ZEXTRA 200MG CAPSULE offers several important benefits that help relieve joint pain, reduce inflammation, and improve daily mobility:
 

  • Relieves Joint Pain and Stiffness: It helps reduce persistent joint pain and stiffness, allowing you to move more freely and comfortably.
  • Targets Joint Inflammation: It acts directly within joint tissues to reduce inflammation, helping prevent ongoing irritation and promote long-term joint comfort.
  • Supports Better Mobility: By easing pain and improving joint flexibility, it helps you carry out everyday activities with greater ease.
  • Gentle on the Stomach: ZEXTRA 200MG CAPSULE works differently from many traditional anti-inflammatory pain relievers and may cause less stomach irritation in some people. However, stomach-related side effects can still occur, so take it with food as advised by your doctor.
     
Side effects of Zextra 200mg Capsule
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Directions for Use

  • Take ZEXTRA 200MG CAPSULE with or without food, or as advised by a doctor.
  • Adhere to your doctor’s guidance regarding the dosage and timing of this medication for optimal effectiveness.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How ZEXTRA 200MG CAPSULE Works

ZEXTRA 200MG CAPSULE contains oxaceprol, an anti-inflammatory medicine that helps relieve joint pain and inflammation associated with conditions such as osteoarthritis. Based on available evidence, ZEXTRA 200MG CAPSULE works differently from many traditional anti-inflammatory medicines. Rather than mainly blocking pain-producing chemicals, it appears to help reduce inflammation by limiting the adhesion and movement of white blood cells into joint tissues while supporting the stability of the collagen framework within the joints. Together, these actions may help reduce the inflammatory response responsible for swelling, pain, and stiffness. Studies suggest that by reducing the build-up of inflammatory cells in the joints, ZEXTRA 200MG CAPSULE may help support joint cartilage health and limit ongoing inflammation associated with joint damage. However, evidence for its long-term cartilage-protective effects remains limited. Together, these actions help reduce joint pain and swelling, improve joint movement, and support long-term joint function.
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Alcohol

Safe if prescribed

ZEXTRA 200MG CAPSULE may not interact with alcohol. However, limit alcohol consumption while on treatment with ZEXTRA 200MG CAPSULE.

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Pregnancy

Caution

ZEXTRA 200MG CAPSULE is not recommended for use in pregnancy unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

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Breast Feeding

Caution

There is no information regarding the use of ZEXTRA 200MG CAPSULE in breastfeeding. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

ZEXTRA 200MG CAPSULE may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy after taking ZEXTRA 200MG CAPSULE.

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Liver

Caution

There is limited information regarding the use of ZEXTRA 200MG CAPSULE in patients with liver diseases. So, please consult your doctor before using this medicine.

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Kidney

Caution

Caution is advised in patients with a history of renal (kidney) diseases such as renal impairment as this may increase the risk of adverse effects of ZEXTRA 200MG CAPSULE. So, please consult your doctor before using this medicine. Your doctor may adjust the dose based on your condition.

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Children

Caution

ZEXTRA 200MG CAPSULE should be used with caution in children. The dose of this medicine will by decided by your doctor based on your child's condition.

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Heart

Safe if prescribed

ZEXTRA 200MG CAPSULE can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Caution

ZEXTRA 200MG CAPSULE should be taken with caution in geriatric patients. Please inform your doctor before using ZEXTRA 200MG CAPSULE.

What if I have taken an overdose of ZEXTRA 200MG CAPSULE

If you accidentally take more than the prescribed amount, seek immediate medical attention or contact a poison control centre right away, even if you do not feel any symptoms.

Diet & Lifestyle Advise

  • Low-impact exercises: Swim, cycle, or walk to keep joint cartilage healthy and lubricated without putting too much stress on your knees or hips.
  • Weight management: Keep a healthy weight to reduce the physical pressure and strain on your weight-bearing joints.
  • Anti-inflammatory foods: Focus on a diet rich in omega-3 fatty acids (like fish or flaxseeds) and colourful vegetables to help naturally ease body inflammation.
  • Stay hydrated: Drink plenty of water throughout the day to support overall joint fluid production.
     
health query

Have a query?

How Soon It Starts Working

The time required for ZEXTRA 200MG CAPSULE to start to work: The time required for ZEXTRA 200MG CAPSULE to show its action is not clinically established. The time for which the effects of ZEXTRA 200MG CAPSULE last: The duration of action for ZEXTRA 200MG CAPSULE is not clinically established.

What if you forget to take ZEXTRA 200MG CAPSULE

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store ZEXTRA 200MG CAPSULE at room temperature, ideally below 25°C (77°F), in a dry place away from direct heat, sunlight, and moisture.

Drug Warnings

  • Check Before Use: Always check the packaging to ensure the medicine has not expired before taking it.
  • Consult Before Taking Other Pain Relievers: Do not start taking any other pain relievers or anti-inflammatory drugs without talking to your doctor first.
  • Inform Your Healthcare Provider Before Surgery: If you are scheduled for any surgery or dental procedure, tell your doctor or dentist that you are taking ZEXTRA 200MG CAPSULE. This is especially important if you also take blood-thinning medicines, as your treatment plan may need to be reviewed before the procedure.
  • Monitor for Unusual Bleeding: If you take blood-thinning medicines, watch for signs of unusual bruising or bleeding and report them to your doctor promptly. 
     

Drug-Drug Interactions

verifiedApollotooltip

Here are the medicines that may interact with ZEXTRA 200MG CAPSULE and increase the risk of side effects:

  • Blood Thinners (such as Warfarin): If you take blood-thinning medicines, your doctor may recommend closer monitoring while you are taking ZEXTRA 200MG CAPSULE, as combining these medicines may increase the risk of bleeding in some people.
  • Other Anti-Inflammatory Pain Relievers: Taking it alongside other anti-inflammatory pain relievers may increase the risk of stomach irritation or ulcers.
     
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with ZEXTRA 200MG CAPSULE when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANALGESICS]

FAQs

ZEXTRA 200MG CAPSULE is used to treat osteoarthritis, a degenerative joint disease.
ZEXTRA 200MG CAPSULE contains ‘Oxaceprol’, which belongs to the class of anti-inflammatory agents. It prevents the accumulation of white blood cells in the affected joints, thereby reducing inflammation. This effect also helps to reduce symptoms such as pain, swelling and stiffness.
ZEXTRA 200MG CAPSULE can act as a pain killer. It effectively reduces pain in patients with osteoarthritis and other inflammatory disorders.
ZEXTRA 200MG CAPSULE is probably safe when used in patients with diabetes. However, consult your doctor before using ZEXTRA 200MG CAPSULE to prevent unpleasant effects.
ZEXTRA 200MG CAPSULE may cause side effects such as stomach pain, nausea, vomiting, diarrhoea, constipation, bloating, indigestion, dizziness, headache and skin rashes. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.
Osteoarthritis is a progressive inflammatory disease, and there is no permanent cure. However, you can effectively manage the symptoms and delay the disease's progression by following the recommendations of your doctor, such as controlling weight, doing optimal exercises and taking medication as advised.
ZEXTRA 200MG CAPSULE may cause side effects such as nausea, vomiting, diarrhoea, stomach pain, constipation, indigestion, bloating or dizziness. If these side effects persist or worsen, please consult your doctor.
Osteoarthritis is a degenerative joint disease that occurs due to breakdown of joint cartilage and underlying bone. The symptoms include joint pain, stiffness, problems moving the joint, tenderness, swelling, crackling or grating sound when moving the affected joints.
You are recommended to consult your doctor before taking ZEXTRA 200MG CAPSULE with diclofenac or other medicines.
It is best to take ZEXTRA 200MG CAPSULE with or after food to minimise the risk of stomach upset and nausea. Talk to your doctor or pharmacist if you experience stomach pain.
You should avoid or limit alcohol while taking this medicine because it can increase the risk of stomach irritation and liver strain.
You should avoid taking this medicine during pregnancy unless your doctor specifically advises it, as its safety during pregnancy is not fully established.
No, it does not cure osteoarthritis, but it helps manage pain, reduce inflammation, and improve joint movement. Talk to your doctor about long-term joint health.
Taking multiple anti-inflammatory medicines together can increase the risk of severe stomach issues. Always talk to your doctor before combining pain relievers.
Stop taking the medicine immediately, as a rash could be a sign of an allergic reaction. Talk to your doctor right away.
Drowsiness is not a common side effect of this medicine, but if you feel dizzy or tired, avoid driving or operating machinery.
ZEXTRA 200MG CAPSULE is available and prescribed in some countries for managing osteoarthritis, but it is not widely included in major international osteoarthritis treatment guidelines. Your doctor will decide whether it is an appropriate option for you based on your symptoms, medical history, available evidence, and local prescribing practices.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - ZEX0020
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