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Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zidovir Oral Solution is used in the treatment of HIV. It contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This inhibits viral replication and thereby prevents the further spread of infection. Common side effects of this medication may include nausea, headache, stomach pain, loss of appetite, vomiting, nausea, cough, diarrhoea, nasal congestion, fever, tiredness, muscle pain, dizziness, and allergic reactions.

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Whats That

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Composition :

ZIDOVUDINE-50MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zidovir Oral Solution

Zidovir Oral Solution is an antiretroviral medicine used in the treatment of HIV. Human Immunodeficiency Virus (HIV) is a retroviral infection that attacks and damages the cells of the immune system. This weakens the ability to fight against infections and diseases. If this condition is left untreated, it can lead to Acquired Immuno Deficiency Syndrome (AIDS). Symptoms of HIV include fever, chills, night sweats, muscle aches, etc. This medicine is also used for the prevention of maternal-fetal HIV transmission.

Zidovir Oral Solution contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection.

Zidovir Oral Solution may cause certain side effects such as nausea, headache, stomach pain, loss of appetite, vomiting, nausea, cough, diarrhea, nasal congestion, fever, tiredness, muscle pain, dizziness, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Zidovir Oral Solution should be taken as advised by your doctor. Your doctor will decide the dose of the medicine based on your health condition. Do not take more than the recommended dose.

Zidovir Oral Solution should be avoided if you are allergic to it. Before taking this medicine, inform your doctor if you have heart problems, liver/kidney diseases, haematological toxicity, severe anemia, hepatomegaly with steatosis, lactic acidosis, or peripheral nephropathy. If you are pregnant and breastfeeding, let your doctor know before taking Zidovir Oral Solution . Zidovir Oral Solution can be used in children only if recommended by the doctor. If prescribed, the child should be carefully monitored for any changes. Zidovir Oral Solution is used to treat the infection but does not cure or prevent it. Inform your doctor about your medical history and the medicines you take to prevent possible interactions.

Uses of Zidovir Oral Solution

Zidovir Oral Solution is used in the treatment and prevention of HIV (Human Immunodeficiency Virus) infection. The detailed uses of Zidovir Oral Solution are as follows:<br/>• Treatment of HIV infection: Zidovir Oral Solution , in combination with other antiretroviral medications, helps reduce HIV levels in the blood and slows disease progression.<br/>• Prevention of mother-to-child transmission: Zidovir Oral Solution is used in HIV-positive pregnant women to lower the risk of passing the infection to their babies.<br/>• Delay progression to AIDS: Zidovir Oral Solution reduces the risk of developing AIDS and associated complications like infections and certain cancers.<br/>• Part of comprehensive HIV management: Zidovir Oral Solution is an nucleoside reverse transcriptase inhibitor (NRTI) that forms a key component of combination antiretroviral therapy (cART), supporting viral suppression and improved quality of life.<br/>

Directions for Use

• Zidovir Oral Solution can be taken with or without food as prescribed by your doctor.• It is usually taken twice daily; however, follow your doctor's advice regarding the dosage and duration.• Swallow the capsule as a whole with a glass of water.• Do not open, chew or break the medicine.

Medicinal Benefits

Zidovir Oral Solution contains Zidovudine, which belongs to the class of protease nucleoside reverse transcriptase inhibitor (NRTI). It works by inhibiting the nucleoside reverse transcriptase enzymes that are necessary for the virus's DNA reproduction. This causes inhibition of viral replication and thereby prevents further spread of infection. Zidovir Oral Solution is used in combination with other antiretroviral medicines to help reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It also helps in improving the quality of life of a patient with HIV. 

Storage

• Store in a cool and dry place away from sunlight.
• Keep Zidovir Oral Solution out of the sight and reach of children.
• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zidovir Oral Solution

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Zidovir Oral Solution may include extreme drowsiness/tiredness, confusion, and seizures. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Zidovir Oral Solution should be avoided if you are allergic to it. It is advised not to take this medicine along with ganciclovir, interferon alpha, ritonavir, stavudine, daunorubicin, bleomycin, idarubicin, and epirubicin, as it can cause serious side effects. Hence, avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, hematological toxicity, anemia, hepatomegaly with steatosis, lactic Acidosis, and peripheral nephropathy, on priority. It is not known whether Zidovir Oral Solution can be given to pregnant and breastfeeding women. Hence, inform your doctor if you are pregnant and breastfeeding before receiving Zidovir Oral Solution . Zidovir Oral Solution can be used in children only if recommended by the pediatrician. If prescribed, the child should be carefully monitored for any changes. Zidovir Oral Solution is used to treat the infection but does not cure or prevent it. Zidovir Oral Solution is used to treat the infection but does not cure or prevent it. This medicine is used in combination for the treatment of HIV infection. This medicine may cause dizziness; hence, avoid driving or operating machines while taking Zidovir Oral Solution .

Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Eat vitamin-rich and nutrient-rich food such as vegetables and fruit as it helps to boost your immune system. Try to take lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Never share personal items with body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS
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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption while taking Zidovir Oral Solution .

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Pregnancy

Consult your doctor

If you are pregnant or suspect you may be pregnant, inform your doctor before taking Zidovir Oral Solution . Your doctor will prescribe a suitable dose of this medicine to prevent maternal-fetal HIV transmission.

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Breast Feeding

Unsafe

Zidovir Oral Solution is excreted in milk. You should not nurse your child if you are taking this medicine because of the risk of HIV-1 transmission and serious adverse reactions in breastfeeding infants.

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Driving

Unsafe

Avoid driving vehicles after taking Zidovir Oral Solution as it may cause dizziness and affect your ability to drive.

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Liver

Caution

Zidovir Oral Solution should be used with caution in patients with mild to moderate liver impairment. In case of severe liver problems, it may increase the risk of hematologic toxicity. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Zidovir Oral Solution should be used with caution in patients with kidney impairment. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

Please consult your doctor. Your doctor will decide the dose of this medicine based on the age and condition of your child.

Have a query?

FAQs

Country of origin

India

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013.
Other Info - ZID0003

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