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compositionComposition:ISOTRETINOIN-10MG
prescriptionPrescription Medicine
Zinderm Iso-10 Capsule

Zinderm Iso-10 Capsule is used to treat a severe form of acne known as nodular acne when other treatments are ineffective. It contains Isotretinoin, which works by stopping the sebaceous glands from producing too much sebum and slowing the production of certain natural substances that can cause acne. Some people may experience dry skin and headaches. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ISOTRETINOIN-10MG

Manufacturer/Marketer :

Wockhardt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zinderm Iso-10 Capsule

Zinderm Iso-10 Capsule belongs to a class of drugs called retinoids, primarily used to treat a severe form of acne known as nodular acne that has not responded to other treatments, including antibiotics.

Zinderm Iso-10 Capsule contains 'isotretinoin', which works by stopping the sebaceous glands from producing too much sebum and slowing the production of certain natural substances that can cause acne.

In some cases, Zinderm Iso-10 Capsule may cause side effects like dry skin, headache, cold symptoms, and vision problems. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Zinderm Iso-10 Capsule if you are allergic to any of its components, are pregnant or breastfeeding. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.

Uses of Zinderm Iso-10 Capsule

Zinderm Iso-10 Capsule used in the treatment of nodular acne. The detailed uses of Zinderm Iso-10 Capsule are as follows:

  • Treatment for nodular acne: Zinderm Iso-10 Capsule reduces acne lesions and treats severe nodular acne that is not responding to other treatments.
  • Sebum Reduction: Zinderm Iso-10 Capsule prevents acne by reducing oil production, avoiding the growth of acne, and shrinking the sebaceous gland.
  • Enhancement of Skin Texture: By encouraging the removal of dead skin cells and avoiding clogged pores, Zinderm Iso-10 Capsule helps to improve skin texture.

Key Benefits

  • Zinderm Iso-10 Capsule used to treat severe nodular acne, especially when other treatments (like antibiotics) have failed.
  • It reduces oil (sebum) production by shrinking the sebaceous glands, helping to prevent clogged pores.
  • Zinderm Iso-10 Capsule reduces the buildup of dead skin cells and bacteria in pores. Thereby, prevents the formation of new acne.
  • Helps reduce redness, swelling, and tenderness of acne lesions.
  • By controlling severe breakouts, it helps reduce the risk of permanent scarring.
  • It often provides sustained acne clearance even after treatment ends.
Side effects of Zinderm Iso-10 Capsule
  • Exercise and a healthy diet can help manage high cholesterol, but consult your doctor about medication if lifestyle changes are not enough.
  • Avoid foods high in cholesterol, saturated fat, and trans fats, such as egg yolks, cheese, fried foods, pastries, ice cream, and red meat.
  • Increase your intake of vegetables, fruits, oats, whole grains, lentils, and beans to boost fibre consumption.
  • Include foods rich in monounsaturated fats, like nuts, avocados, olive oil, and oily fish.
  • Exercise regularly for 30 minutes and maintain a healthy weight.
  • Quit smoking and limit excessive alcohol consumption, as both can negatively impact your cholesterol levels.
Managing Medication-Triggered Epistaxis (Nosebleed): A Step-by-Step Guide:
  • If you experience nosebleeds or unusual bleeding after taking medication, seek medical attention right away and schedule an appointment to discuss your symptoms with your doctor.
  • Your doctor may adjust your treatment plan by changing the dosage, switching to a different medication, or stopping the medication.
  • If your doctor advises, take steps to manage bleeding and promote healing, such as applying pressure, using saline nasal sprays, or applying a cold compress, using humidifiers, avoiding blowing or picking your nose, and applying petroleum jelly to the nostrils.
  • Schedule follow-up appointments with your doctor to monitor progress, adjust treatment plans, and prevent future episodes.
Managing Medication-Triggered Cheilitis (Inflammation of the lips): A Step-by-Step Guide:
  • Consult your doctor if you experience lip inflammation, redness, or irritation after taking medication.
  • Your doctor will assess your condition, investigate possible causes, and design a treatment plan.
  • To soothe and moisturize the lips, use topical creams or ointments like petroleum jelly or lip balm.
  • Practice good lip care by keeping your lips clean, avoiding irritants, and staying hydrated.
  • If your condition worsens or persists, speak with your doctor about further therapy.
  • If you notice increased red blood cell sedimentation rate (ESR) after starting a medication, consult your doctor so that they may advise possible medication adjustments.
  • Regular blood tests are advised to monitor your ESR levels to assess the effectiveness of any treatment plan.
  • Eat a well-balanced diet rich in nutrients and antioxidants to reduce inflammation.
  • Drink lots of water to maintain proper blood viscosity.
  • Do regular physical activity as it helps to manage chronic conditions that may contribute to high ESR.
  • If you a smoker, quit smoking as it can negatively impact ESR levels.
  • Exercise for at least 30 minutes most days of the week.
  • Limit alcohol consumption.
  • Consider a low carbohydrate diet that limits grains, starchy vegetables and fruit. Include foods rich in protein and fat.
  • Avoid excess sugar, fatty foods and carbohydrates.
  • Aim for weight loss as it helps to improve cardiovascular health and minimize the risk of complications related to obesity.
  • Apply a gentle lip balm with ingredients such as castor seed oil or shea butter.
  • Ensure you are hydrated by drinking plenty of water; this helps heal your lips.
  • Avoid licking your lips or picking at them.
  • Use a humidifier at home, particularly at night, to maintain moisture in the air.
  • Protect your lips from sun exposure by using SPF lip balm and avoid using any irritating components.
  • Stay away from metal objects that could irritate your lips.
  • Consume a vitamin-rich diet to enhance the health of your skin overall.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.

Directions for Use

  • Take Zinderm Iso-10 Capsule with food or as advised by your doctor.
  • It is advised to take Zinderm Iso-10 Capsule twice a day; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Zinderm Iso-10 Capsule as a whole with a glass of water.
  • Do not crush, chew or break it.

How Zinderm Iso-10 Capsule Works

Zinderm Iso-10 Capsule contains 'isotretinoin', which works by stopping the sebaceous glands from producing too much sebum and slowing the production of certain natural substances that can cause acne.
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Alcohol

Unsafe

Avoid consumption of alcohol with Zinderm Iso-10 Capsule as it may increase the risk of liver damage and cause a rise in cholesterol levels.

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Pregnancy

Unsafe

Zinderm Iso-10 Capsule is a Category X pregnancy drug and is considered unsafe for pregnant women as it may cause severe birth defects. Please consult a doctor if you are pregnant or planning to become pregnant.

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Breast Feeding

Unsafe

Zinderm Iso-10 Capsule may be excreted in breast milk and cause adverse effects in the baby. Please consult a doctor before using Zinderm Iso-10 Capsule while breastfeeding.

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Driving

Caution

Zinderm Iso-10 Capsule may reduce night vision in some patients. Therefore, drive only if you are alert after taking Zinderm Iso-10 Capsule.

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Liver

Unsafe

Zinderm Iso-10 Capsule is usually not recommended for patients with impaired liver function. If you have any concerns regarding the use of Zinderm Iso-10 Capsule in patients with liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding the use of Zinderm Iso-10 Capsule in patients with kidney problems, please consult a doctor.

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Children

Unsafe

Zinderm Iso-10 Capsule is not recommended for children below 12 years of age.

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Heart

Consult your doctor

If you have any concerns regarding the use of Zinderm Iso-10 Capsule in patients with heart problems, please consult a doctor.

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Geriatrics

Consult your doctor

Limited information is available. Please consult your doctor.

What if I have taken an overdose of Zinderm Iso-10 Capsule

Do not take more than the prescribed dose of Zinderm Iso-10 Capsule as it may cause an overdose. The symptoms of overdose include vomiting, dizziness, headache, stomach pain, loss of balance or coordination, warmth or tingling in your face and swollen or cracked lips. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Regular exercise can improve your mood and self-esteem, though it doesn't clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.
  • Avoid sun exposure while using Zinderm Iso-10 Capsule as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
  • Regular hair washing is also recommended, and hair contact with the face should be avoided.
  • Remove the makeup completely before going to bed.

Have a query?

How Soon It Starts Working

The time required for Zinderm Iso-10 Capsule to start to work: Zinderm Iso-10 Capsule ideally shows its action within 1 to 4 hours after administration. The time for which the effects of Zinderm Iso-10 Capsule last: The effect of Zinderm Iso-10 Capsule lasts for 5 days.

What if you forget to take Zinderm Iso-10 Capsule

Skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Zinderm Iso-10 Capsule if you are allergic to any of its components, are pregnant or breastfeeding.
  • Inform your doctor if you have asthma, diabetes, hypervitaminosis A (high levels of vitamin A), liver or heart problems, weak bones, osteoporosis (bone loss), anorexia nervosa (an eating disorder where people eat too little), any mental problems such as psychosis (loss of contact with reality) or depression before taking Zinderm Iso-10 Capsule.
  • If you have depression or any suicidal thoughts while taking Zinderm Iso-10 Capsule or after stopping treatment with Zinderm Iso-10 Capsule, please consult your doctor.
  • Do not undergo any cosmetic procedures while taking Zinderm Iso-10 Capsule and for a minimum of 6 months after stopping treatment with Zinderm Iso-10 Capsule, as it may increase the risk of scarring.
  • Stop taking Zinderm Iso-10 Capsule and call your doctor right away if you think you are pregnant, miss a menstrual period, or have had sex without using two forms of birth control.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interaction: Zinderm Iso-10 Capsule may interact with anticonvulsants (phenytoin), antibiotics (doxycycline, demeclocycline, minocycline, oxytetracycline, tetracycline, eravacycline), and vitamins (vitamin A).

Drug-Food Interaction: Do not use Zinderm Iso-10 Capsule with St. John's Wort (a herbal supplement used to treat depression) as it may reduce the effectiveness of hormonal contraceptive pills, raising the risk of pregnancy.

Drug-Disease Interaction: If you have asthma, diabetes, liver or heart problems, hypervitaminosis A (high levels of vitamin A), weak bones, osteoporosis (bone loss), anorexia nervosa (an eating disorder where people eat too little), any mental problems such as psychosis (loss of contact with reality) or depression before taking Zinderm Iso-10 Capsule.

IsotretinoinDoxycycline
Critical
IsotretinoinOxytetracycline
Critical

Drug-Drug Interactions

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IsotretinoinDoxycycline
Critical
How does the drug interact with Zinderm Iso-10 Capsule:
Taking Zinderm Iso-10 Capsule with Doxycycline may increase the risk of a rare condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Zinderm Iso-10 Capsule and Doxycycline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinOxytetracycline
Critical
How does the drug interact with Zinderm Iso-10 Capsule:
Co-administration of Zinderm Iso-10 Capsule with Oxytetracycline can increase the risk of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Zinderm Iso-10 Capsule and Oxytetracycline together is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinDemeclocycline
Critical
How does the drug interact with Zinderm Iso-10 Capsule:
Taking Zinderm Iso-10 Capsule with Demeclocycline may increase the risk of a rare and serious condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Zinderm Iso-10 Capsule and Demeclocycline together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting doctor.
IsotretinoinMinocycline
Severe
How does the drug interact with Zinderm Iso-10 Capsule:
Taking Zinderm Iso-10 Capsule with minocycline may increase the risk of a rare and serious condition called pseudotumor cerebri (increased pressure in the brain).

How to manage the interaction:
Although taking Zinderm Iso-10 Capsule and minocycline together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as headache, nausea, vomiting, and visual disturbances, consult a doctor. Do not stop using any medications without consulting a doctor.
IsotretinoinTeriflunomide
Severe
How does the drug interact with Zinderm Iso-10 Capsule:
Taking Zinderm Iso-10 Capsule with teriflunomide may affect liver and causes liver problems.

How to manage the interaction:
Although taking Zinderm Iso-10 Capsule and teriflunomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, light-coloured stools, and/or yellowing of the skin or eyes. Do not stop using any medications without consulting doctor.
IsotretinoinTretinoin
Severe
How does the drug interact with Zinderm Iso-10 Capsule:
Taking Zinderm Iso-10 Capsule together with tretinoin may increase the risk of hypervitaminosis A (excessive vitamin A-related effects).

How to manage the interaction:
Although taking Zinderm Iso-10 Capsule and tretinoin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as increased pressure in the brain (headache, nausea, vomiting, visual disturbances) or liver damage (fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, yellowing of the skin or eyes). Do not stop using any medications without consulting doctor.
IsotretinoinLomitapide
Severe
How does the drug interact with Zinderm Iso-10 Capsule:
Taking Zinderm Iso-10 Capsule with lomitapide may affect liver and cause liver problems.

How to manage the interaction:
Although taking Zinderm Iso-10 Capsule and lomitapide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
IsotretinoinAminolevulinic acid
Severe
How does the drug interact with Zinderm Iso-10 Capsule:
Taking Zinderm Iso-10 Capsule with aminolevulinic acid may increase the risk of a severe sunburn.

How to manage the interaction:
Although taking Zinderm Iso-10 Capsule and aminolevulinic acid together can possibly result in an interaction, it can be taken if your doctor has prescribed it. After taking you should avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Incase you experience any unusual symptoms, consult a doctor. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[RETINOIDS]

FAQs

Zinderm Iso-10 Capsule is used to treat a severe form of acne known as nodular acne that cannot be cleared by any other treatments, including antibiotics.

Zinderm Iso-10 Capsule may cause decreased night vision temporarily or permanently in some patients. It is not necessary for everyone taking Zinderm Iso-10 Capsule to experience this side effect. Avoid driving after taking Zinderm Iso-10 Capsule if you are unable to see in the dark, and consult a doctor if you notice any changes in vision or have painful or persistent dry eyes.

Zinderm Iso-10 Capsule may increase the skin sensitivity to sunlight. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen and wear protective clothing while going out to prevent sunburn.

No, you are not recommended to undergo any cosmetic procedures to smoothen your skin, including waxing, laser procedures or dermabrasion (an exfoliating technique to remove outer layers of skin with a rotating instrument) while taking Zinderm Iso-10 Capsule and for a minimum of 6 months after stopping treatment with Zinderm Iso-10 Capsule, as it may increase the risk of scarring.

You are not recommended to take vitamin A supplements with Zinderm Iso-10 Capsule as it may cause hypervitaminosis A (excessive levels of vitamin A in the body), leading to an increased risk of adverse effects. However, please consult a doctor before taking other medicines or supplements with Zinderm Iso-10 Capsule.

No, Zinderm Iso-10 Capsule is not recommended for use during pregnancy as it may cause severe birth defects. Also, it is advised to use effective contraceptive measures before, while taking Zinderm Iso-10 Capsule and after 1 month of stopping treatment with Zinderm Iso-10 Capsule. However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Zinderm Iso-10 Capsule.

Zinderm Iso-10 Capsule is safe to use if prescribed by the doctor. Use Zinderm Iso-10 Capsule exactly as advised by the doctor as it is associated with adverse effects.

Zinderm Iso-10 Capsule is not a steroid. It is a retinoid used to treat severe nodular acne.

Pregnancy tests, lipid profile tests, liver function tests, blood glucose tests, and creatine phosphokinase (CPK) tests are recommended tests during Zinderm Iso-10 Capsule treatment.

In most cases, the effect of Zinderm Iso-10 Capsule is permanent. Isotretinoin is a clinically effective anti-acne therapy that shows significant improvement in many patients.

Zinderm Iso-10 Capsule does not cause cancer. In fact, isotretinoin slows the growth of cancer cells by activating protein receptors in cells, including cancer cells.

Long-term use of Zinderm Iso-10 Capsule, even in low doses, has not been studied and is not recommended. Hence, long-term side effects of Zinderm Iso-10 Capsule have not been established.

Zinderm Iso-10 Capsule is not known to affect male fertility.

Zinderm Iso-10 Capsule might elevate liver enzymes. Therefore, regular liver function tests are advised.

Side effects of Zinderm Iso-10 Capsule include chapped lips and dry skin, eyes, nose, or lips. These side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

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Author Details

Veda MaddalaDoctor badge

Written By

  • Veda Maddala

    M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India
Other Info - ZIN0344
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