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About TRETINOIN

TRETINOIN belongs to the class of drugs known as retinoids (synthetic or man-made vitamin A). TRETINOIN is primarily used to treat acne (pimples) and sun-damaged skin. Acne is a skin condition that is common and occurs when hair follicles are blocked with dead skin cells and oil.

TRETINOIN contains tretinoin, also known as retinoic acid (a form of vitamin A) that loosens and unblocks pores on the skin’s surface by reducing the oil secretion in the skin. This prevents the formation of pimples, whiteheads, and blackheads.

TRETINOIN is for external use only. Your doctor will advise you on how often you use TRETINOIN based on your medical condition. Avoid contact of TRETINOIN with nose, mouth, eyes, ears, or vagina. In case TRETINOIN comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience dry skin, peeling, redness, burning, itching, or stinging sensation of the skin. Most of these side effects of TRETINOIN do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to TRETINOIN or any other medicines, please tell your doctor. If you are pregnant, nursing mother, or planning for pregnancy, it is advised to consult a doctor before using TRETINOIN. Avoid sun exposure while using TRETINOIN as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use a sunscreen lotion (SPF) while going out to protect your skin from sunburn. Do not apply TRETINOIN in large amounts than prescribed as it does not give quick or better results but causes peeling, marked redness, or skin discomfort. Patients with a history of depression, eczema, history of skin cancer, and fish allergies should use TRETINOIN with caution.

Uses of TRETINOIN

Acne, Wrinkles

Medicinal Benefits

TRETINOIN is a form of vitamin A (retinoid) that loosen and unblock pores on the skin’s surface by reducing the oil secretion in the skin. This prevents the formation of pimples, whiteheads, and blackheads.

Directions for Use

Wash your hands before and after applying TRETINOIN. Before using it, try to clean and dry the affected skin area. Applying TRETINOIN to wet skin may cause skin irritation, so try not to wash the treated area. Also do not apply other skin products for at least 1 hour after applying TRETINOIN. Wash the face with mild soap and pat the skin dry. Take a small pearl-sized amount of TRETINOIN on the fingertip and apply on the clean and dry affected area once a day in the evening. Avoid contact of TRETINOIN with nose, mouth, eyes, ears or vagina. In case TRETINOIN comes in contact with these areas accidentally, rinse with water thoroughly.

Storage

Store in a cool and dry place away from sunlight

Side Effects of TRETINOIN

  • Dry skin
  • Peeling
  • Skin redness
  • Burning
  • Itching
  • Stinging sensation

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to tretinoin or any other medicines, please inform your doctor. If skin irritation, redness, burning, or stinging sensation worsens at the site of application, stop using TRETINOIN and consult a doctor. If you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using TRETINOIN. Avoid sun exposure, use a sunscreen lotion and wear protective clothing while going out in the sun as TRETINOIN may make the skin more sensitive to the sun. Do not apply TRETINOIN in large amounts than prescribed as it does not give quick or better results but causes peeling, marked redness, or skin discomfort. Use TRETINOIN with caution when used together with medicated or abrasive soaps, cleansers, shampoos, astringents, products with high concentrations of alcohol, electrolysis, hair depilatories, or waxes or topical medications as they may increase skin irritation.

Drug Interactions

Drug-Drug Interaction: TRETINOIN may interact with vitamin A-related drugs known as retinoids (isotretinoin), photosensitizing agents (aminolevulinic acid, methoxsalen, porfirmer, verteporfin), sensitizer (methyl aminolevulinate), keratolytic agents (benzoyl peroxide, salicylic acid, sulfur), antiseptic (resorcinol).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have eczema (itchy, swelling of the skin) or any other skin condition, inform your doctor before taking TRETINOIN.

Drug-Drug Interactions Checker List:

  • ISOTRETINOIN
  • AMINOLEVULINIC ACID
  • METHOXSALEN
  • PORFIRMER
  • VERTEPORFIN
  • METHYL AMINOLEVULINATE
  • BENZOYL PEROXIDE
  • SALICYCLIC ACID
  • SULFUR
  • RESORCINOL
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Interaction of alcohol with TRETINOIN is unknown. Please consult a doctor before consuming alcohol while using TRETINOIN.

    • Safety Warning

      Pregnancy

      unsafe

      TRETINOIN is Category C pregnancy drug and is considered unsafe for pregnant women. Therefore, if you are pregnant, inform your doctor before using TRETINOIN.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether TRETINOIN is excreted in human milk. Please consult a doctor before using TRETINOIN while breastfeeding.

    • Safety Warning

      Driving

      safe if prescribed

      TRETINOIN usually does not affect your ability to drive or operate machinery.

    • Safety Warning

      Liver

      caution

      If you have any concerns regarding the use of TRETINOIN in patients with liver problems, please consult a doctor.

    • Safety Warning

      Kidney

      caution

      If you have any concerns regarding the use of TRETINOIN in patients with kidney problems, please consult a doctor.

    • Safety Warning

      Children

      unsafe

      TRETINOIN is not recommended for children below 18 years as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Avoid sun exposure while using TRETINOIN as it may make the skin more sensitive to sunlight and cause sunburn. Wear protective clothing and use sunscreen while going out to protect your skin from sunburn.
    • Regular exercise can improve your mood and self-esteem though it doesn’t clear acne. Take a shower immediately after finishing exercise as sweat may irritate acne.
    • Do regular hair wash and avoid hair falling across the face.
    • Use water-based cosmetic products and remove the make-up completely before going to bed.

    Special Advise

    • ​​​​​​Do not apply TRETINOIN in large amounts than prescribed as it does not give quick or better results but causes peeling, marked redness or skin discomfort.
    • Do not squeeze spots or try to clean blackheads as it may worsen them and cause permanent scarring.

    Patients Concern

    Disease/Condition Glossary

    Acne: Acne is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads and blackheads. Acne affects people of all ages but is most common among teenagers. The symptoms of acne include pus-filled pimples, uninflamed (not swollen) blackheads, red, large and tender bumps.

    FAQs

    Does TRETINOIN make skin sensitive to sunlight?

    TRETINOIN may increase the skin sensitivity to sunlight in the treated areas. Therefore, avoid or limit exposure to sunlight and sunlamps. You are advised to use sunscreen with a minimum SPF 15 and wear protective clothing while going out to prevent sunburn.

    Can I use cosmetics after applying TRETINOIN?

    You are recommended to use cosmetics after 1 hour of applying TRETINOIN but avoid cosmetics with a strong drying effect as they may increase skin irritation. If you are using any cosmetics, clean your face before applying TRETINOIN again.

    Does TRETINOIN cause skin irritation?

    Yes, TRETINOIN may cause skin irritation, burning sensation or itching at the site of application. Extreme weather conditions such as cold or wind may cause more irritation in patients using TRETINOIN containing products. However, if the irritation worsens, stop using TRETINOIN and consult a doctor.

    Can I use moisturizers with TRETINOIN?

    You are advised to use moisturizers in the morning every day to prevent dryness in the treated areas.

    Does TRETINOIN remove wrinkles?

    TRETINOIN does not remove wrinkles completely or repair skin damaged by the sun. TRETINOIN may reduce fine wrinkles, especially when used along with other skincare products.

    How long should I use TRETINOIN?

    You are recommended to use TRETINOIN for as long as your doctor has prescribed it. However, the course of treatment with TRETINOIN takes up to 6 months for effective results.

    Available Medicines for

    TRETINOIN