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compositionComposition:CEFUROXIME-125MG
prescription
Prescription Medicine
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Zion DS 125mg Oral Drops is used to treat bacterial infections. It contains Cefuroxime, which works by killing infection-causing bacteria. It may cause common side effects like headache, dizziness, stomach upset, and unpleasant taste in the mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

CEFUROXIME-125MG

Manufacturer/Marketer :

Iifa Healthcare

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Zion DS 125mg Oral Drops

Zion DS 125mg Oral Drops is an antibiotic prescribed to treat a variety of bacterial infections, including middle ear infections, throat infections, sinus infections, and urinary tract infections. It works by stopping the growth of bacteria, helping your body clear the infection and preventing it from spreading further. This medication is only effective against bacterial infections and will not work for viral illnesses such as the common cold or flu.

To get the best results, you must take Zion DS 125mg Oral Drops consistently at evenly spaced intervals throughout the day as directed by your doctor. This oral medication should be taken with food, as this helps your body absorb the medicine much better and reduces the risk of an upset stomach. Drinking plenty of fluids, getting adequate rest, and eating a balanced diet will also support your body’s recovery during treatment.

While taking this medicine, you may experience mild side effects like nausea, mild diarrhoea, or a temporary, unusual taste in your mouth. Most of these symptoms are mild and go away on their own, but you should contact your doctor immediately if you develop severe, watery diarrhoea, a high fever, or stomach cramps. Always consult your doctor if you experience any unusual or persistent symptoms.

Talk to your doctor before starting Zion DS 125mg Oral Drops if you have a history of kidney disease, liver disease, or severe stomach disorders such as colitis (inflammation of the large intestine). Kidney disease may affect how cefuroxime is removed from the body and could require dose adjustments. Do not take this medicine if you have a known severe allergy to cephalosporin antibiotics or if you have had a severe allergic reaction to penicillin. Your doctor will help determine if this medication is safe for your specific health history.

Certain medications, such as antacids or drugs that reduce stomach acid, can interfere with how your body absorbs Zion DS 125mg Oral Drops, making it less effective. Limit or avoid alcohol during treatment to prevent stomach irritation, and consult your doctor if you are pregnant, breastfeeding, or managing health conditions at an older age.

Uses of Zion DS 125mg Oral Drops

Zion DS 125mg Oral Drops may be prescribed for the following bacterial infections:

  • Pharyngitis and tonsillitis: Zion DS 125mg Oral Drops helps clear bacterial infections of the throat and tonsils, relieving painful swallowing and reducing swelling.
  • Acute middle ear infections: It targets the bacteria causing painful fluid buildup behind the eardrum, resolving ear pain and pressure.
  • Acute bacterial sinusitis: It eliminates bacterial infections in the nasal passages, relieving facial pain, congestion, and headaches.
  • Urinary tract infections: It treats bacterial infections in the bladder or kidneys, easing symptoms like burning urination and frequent urges.
  • Skin and soft tissue infections: It clears bacterial infections on the skin, reducing redness, warmth, swelling, and pain.
  • Chronic bronchitis flare-ups: It helps treat bacterial flare-ups in patients with ongoing bacterial lung airway irritation, improving breathing.

Key Benefits

Zion DS 125mg Oral Drops may provide the following benefits when used as prescribed.

  • Relieves Infection Symptoms: By eliminating the bacteria causing the infection, Zion DS 125mg Oral Drops may help reduce symptoms such as fever, pain, swelling, congestion, burning during urination, or discomfort associated with bacterial infections.
  • Helps Clear Bacterial Infections: Zion DS 125mg Oral Drops works against a wide range of susceptible bacteria, helping the body overcome infections affecting the ears, throat, sinuses, urinary tract, skin, and respiratory system.
  • Reduces the Risk of Complications: Prompt and appropriate treatment with Zion DS 125mg Oral Drops may help prevent bacterial infections from worsening, spreading to other parts of the body, or causing more serious health problems.
  • Supports Faster Recovery: By controlling the infection effectively, Zion DS 125mg Oral Drops may help improve overall well-being and allow patients to return to normal daily activities sooner.
  • Provides Targeted Antibacterial Action: Zion DS 125mg Oral Drops specifically targets bacteria responsible for the infection and is designed to treat bacterial illnesses without affecting viral infections such as the common cold or flu.

Directions for Use

  • Zion DS 125mg Oral Drops can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Zion DS 125mg Oral Drops as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Zion DS 125mg Oral Drops Works

Cefuroxime, the active ingredient in Zion DS 125mg Oral Drops, belongs to a class of antibiotics known as cephalosporins. It works by interfering with the formation of the bacterial cell wall, a protective outer layer that bacteria need to survive and multiply. Cefuroxime binds to specific proteins called penicillin-binding proteins (PBPs), which bacteria use to build and strengthen this protective outer layer. By blocking these proteins, cefuroxime prevents the bacteria from forming a proper cell wall. As a result, the bacterial cell wall becomes weak and unstable, causing the bacteria to break down and die. Since human cells do not have cell walls, cefuroxime specifically targets the bacteria causing the infection without affecting the body's own cells.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Zion DS 125mg Oral Drops.

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Pregnancy

Safe if prescribed

Zion DS 125mg Oral Drops is a pregnancy category B drug. So, Zion DS 125mg Oral Drops can be safely taken by pregnant women if prescribed by the doctor.

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Breast Feeding

Caution

Zion DS 125mg Oral Drops is excreted in human milk; caution should be exercised. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Driving

Caution

No studies on the effects on the ability to drive and use machines have been performed. However, as this medicine may cause dizziness, patients should be warned to be cautious when driving or operating machinery.

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Liver

Caution

Consult your doctor; there is no substantial research yet on the use of Zion DS 125mg Oral Drops in patients with liver problems.

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Kidney

Caution

Consult your doctor, as there is no substantial research yet on the use of Zion DS 125mg Oral Drops in people with kidney problems.

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Children

Safe if prescribed

Zion DS 125mg Oral Drops can be given safely to children provided the dose has been prescribed by a child specialist. However, there is no clinical evidence of using Zion DS 125mg Oral Drops in children under the age of 3 months.

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Heart

Consult your doctor

Please consult your doctor before using Zion DS 125mg Oral Drops if you have pre-existing heart problems. Your doctor will prescribe Zion DS 125mg Oral Drops if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Zion DS 125mg Oral Drops to geriatric patients. Your doctor will prescribe Zion DS 125mg Oral Drops if the benefits outweigh the risks.

What if I have taken an overdose of Zion DS 125mg Oral Drops

Taking too much of this medicine may cause nausea, vomiting, diarrhoea, dizziness, or stomach discomfort. In severe overdose situations, particularly in people with significant kidney impairment or very high drug levels, serious effects on the nervous system, including seizures, may occur. If you suspect an overdose, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Take probiotics: Consider consuming probiotic-rich foods like yoghurt or taking a probiotic supplement a few hours after your antibiotic dose to help maintain a healthy balance of gut bacteria.
  • Stay hydrated: Drink plenty of water throughout the day, especially if you experience mild diarrhoea, to keep your body well-hydrated and flush out toxins.
  • Complete the full course: Always finish the entire prescription, even if your symptoms disappear. Stopping early can allow the remaining bacteria to multiply and become resistant to the medication.
  • Rest and recover: Give your body ample time to rest while fighting off the infection, as physical exertion can slow down your recovery process.
health query

Have a query?

How Soon It Starts Working

The time required for Zion DS 125mg Oral Drops to start to work: Zion DS 125mg Oral Drops ideally shows its action within 2 to 3 hours after administration. The time for which the effects of Zion DS 125mg Oral Drops last: The effect of Zion DS 125mg Oral Drops lasts for 8 hours.

What if you forget to take Zion DS 125mg Oral Drops

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store the tablet form of Zion DS 125mg Oral Drops at room temperature, between 15°C and 30°C (59°F to 86°F), in a dry place away from direct heat and moisture. Do not store them in the bathroom.

Drug Warnings

  • Check the medication: Before taking, inspect the tablets or liquid. Do not use the liquid suspension if it has changed colour significantly or contains unusual clumps.
  • Do not treat viruses: Remember that Zion DS 125mg Oral Drops is only for bacterial infections; using it for colds or flu will not cure the illness and can lead to antibiotic resistance.
  • Watch for severe diarrhoea: If you develop severe, watery diarrhoea during or up to several weeks after stopping treatment, contact your doctor immediately before taking any anti-diarrhoea medications, as these can make the condition worse.
  • Monitor kidney function: If you are taking this medicine for a prolonged period, your doctor may occasionally order blood tests to check how well your kidneys are working.
  • Inform other healthcare providers: Let your dentist, surgeon, or any other doctor know that you are currently taking Zion DS 125mg Oral Drops, as it can occasionally interfere with certain medical or lab tests (like urine sugar tests).

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Stomach acid reducers (antacids, H2 blockers, proton pump inhibitors): Certain oral formulations of cefuroxime may be absorbed less effectively when taken with medicines that reduce stomach acid. Your doctor or pharmacist can advise you on appropriate timing if these medicines are needed together.
  • Oral contraceptives (birth control pills): Cefuroxime is not known to significantly reduce the effectiveness of hormonal contraceptives. However, if you experience severe vomiting or diarrhoea while taking the antibiotic, contraceptive absorption may be affected. Consult your doctor or pharmacist if you have concerns about contraception during treatment.
  • Gout medications (probenecid): Probenecid can slow down how quickly your kidneys remove Zion DS 125mg Oral Drops from your system, leading to higher levels of the antibiotic in your blood and increasing the risk of side effects.

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verifiedApollotooltip
  • Food: Taking Zion DS 125mg Oral Drops with food significantly increases its absorption rate in your body. Avoid taking it on an empty stomach to ensure it works at its best.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

FAQs

Zion DS 125mg Oral Drops is used to treat a wide range of bacterial infections. It helps in the treatment of urinary tract infections (UTI), mild to moderate lower respiratory tract infections (bronchitis), severe lower respiratory tract infections (pneumonia), pyelonephritis (kidney inflammation due to the bacterial infection), uncomplicated gonorrhoea (sexually transmitted infection), and Lyme disease (caused due to biting of infected black-legged tick insect).
Zion DS 125mg Oral Drops is a broad-spectrum antibiotic that kills a wide range of bacteria (bactericidal). It kills the bacterial cell by binding to the outer layer of the bacteria and blocking the activity of the enzyme that makes peptidoglycan (a vital component of the bacterial cell wall). As a result, the bacterial cell cannot grow and multiply and finally gets killed.
No, it is a prescribed drug, given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side effects.
You should avoid taking Zion DS 125mg Oral Drops with oral birth control pills, medicines that reduce gastric acidity (like antacids, omeprazole), immunosuppressing drugs (mycophenolate or mycophenolic), medicines used for reducing uric acid (probenecid), and some urinary glucose tests. Besides this, it also interacts with typhoid and BCG vaccines.
Depending upon the severity of your medical condition, your doctor may prescribe it to you daily for a specific duration. The usual dose of Zion DS 125mg Oral Drops is 5-10 days, but depending on your current infection state, your doctor may extend your dose intake for more days.
Try to stay well hydrated by drinking at least six glasses of water or other fluids per day. Keep your underwear clean and try to use cotton underwear to avoid the spread of infection. Always keep your bladder empty as much as possible by peeing regularly. Your doctor may prescribe cranberry juice with antibiotics to treat a urinary tract infection.
After taking an antibiotic, you may need to wait for up to three hours before eating or drinking any dairy products, including milk, butter, yoghurt, and cheese. Grapefruit juice and dietary supplements containing minerals like calcium may also work to dampen the effect of antibiotics.
If you have taken an accidental overdose of Zion DS 125mg Oral Drops, you may have diarrhoea, nausea or vomiting. In rare cases, it can also cause convulsions or seizures (fits). Try to reach out to the doctor in this case.
No. Zion DS 125mg Oral Drops treats only bacterial infection. Cough, flu or cold are usually caused by viruses. So, you should consult a doctor for these conditions.
Yes. Zion DS 125mg Oral Drops may interact with birth control pills and lower their efficiency. So, you should tell your doctor if you are using any birth control pills.
No. You should complete the full course of Zion DS 125mg Oral Drops as your doctor prescribes. You must take Zion DS 125mg Oral Drops at the right dose, times, and for the right number of days.
Zion DS 125mg Oral Drops might be a safer alternative if you are allergic to amoxicillin. However, please consult the doctor before starting Zion DS 125mg Oral Drops.
Zion DS 125mg Oral Drops helps treat respiratory tract infections, ear infections, skin infections, genitourinary infections, and bone infections.
Zion DS 125mg Oral Drops may cause dizziness in some cases. Therefore, drive or operate machinery only if you are alert.
Do not discontinue Zion DS 125mg Oral Drops without consulting the doctor. To treat your infection effectively, continue taking Zion DS 125mg Oral Drops for the prescribed duration even though you feel better.
If you miss a dose of Zion DS 125mg Oral Drops take it as soon as you remember, However, if it is almost time for the scheduled dose, skip the missed dose and take the next dose at the scheduled time.
Zion DS 125mg Oral Drops may interact with other medications. Consult the doctor if you are taking oral birth control pills, antacids, immuno-suppressing drugs, or medicines used for reducing uric acid.
Avoid alcohol consumption as it might lower the effectiveness of Zion DS 125mg Oral Drops.
Zion DS 125mg Oral Drops can be taken by pregnant or breastfeeding women if prescribed by the doctor. Please consult the doctor if you are pregnant, think you are pregnant, planning for pregnancy or breastfeeding.
Side effects of Zion DS 125mg Oral Drops include headache, dizziness, stomach upset, overgrowth of candida (fungal skin infection), and an unpleasant taste in the mouth. Consult the doctor if the side effects persist or worsen.
It is best to avoid alcohol while taking Zion DS 125mg Oral Drops. Alcohol can irritate your stomach, increase the risk of side effects like dizziness and nausea, and dehydrate your body, which can slow down your recovery from the infection. Talk to your doctor or pharmacist if you have concerns.
Taking Zion DS 125mg Oral Drops with a meal or snack helps your body absorb the active ingredients much more effectively, ensuring the infection is treated properly. It also helps protect your stomach lining, reducing the chances of mild side effects like nausea or stomach upset. Talk to your doctor if you struggle to take it with food.
Mild diarrhoea is a common side effect of Zion DS 125mg Oral Drops as it temporarily affects your gut bacteria. However, if you experience severe, watery, or bloody diarrhoea accompanied by stomach cramps, do not take any over-the-counter anti-diarrhoea medicines. This could be a sign of a serious gut infection, and you should talk to your doctor immediately.
Antacids and other stomach acid-reducing medications can significantly lower the absorption and effectiveness of Zion DS 125mg Oral Drops. If you need to take an antacid, it is recommended to space them out by taking the antacid at least two hours before or after your dose of this medication. Talk to your doctor or pharmacist for a safe schedule.
Zion DS 125mg Oral Drops is generally considered safe during pregnancy and breastfeeding, but it should only be used when clearly needed and prescribed by a healthcare provider. The medicine can pass into breast milk in small amounts, so monitor your infant for signs of diaper rash or thrush. Talk to your doctor to weigh the benefits and risks.
Zion DS 125mg Oral Drops is not known to significantly reduce the effectiveness of hormonal contraceptive pills. However, if you experience severe vomiting or diarrhoea while taking the antibiotic, your body may not absorb your contraceptive properly. If this occurs, follow the instructions provided with your contraceptive and consult your doctor or pharmacist for additional guidance.

Disclaimer

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Reference

  1. U.S. Food and Drug Administration (FDA). 050605S048,050672S034Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Product Summary of Product Characteristics (SmPC). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Electronic Medicines Compendium (EMC). Pil.3810 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  4. Drugs.com Clinical Review Team. Cefuroxime Patient Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Cefuroxime [EMC SmpC]. 2025. [Accessed on 29 Oct. 2025]Check here
  6. Cefuroxime Cefuroxime. 2025. [Accessed on Feb 2 2026]Check here
  7. Zinnat Tablets 125mg - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 27 Oct 2025]Check here

Country of origin

India

Manufacturer/Marketer address

Bmw House 15/3, Bmw Street, Lalpur Road, Gwarighat, Jabalpur - 482008 Madhya Pradesh, India
Other Info - ZI95992
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