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compositionComposition:GLIMEPIRIDE-2MG+PIOGLITAZONE-15MG
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Prescription Medicine
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Zipio G 15mg/2mg Tablet is used to treat type 2 diabetes mellitus. It contains Pioglitazone and Glimepiride which work by causing the pancreas to produce more amount of insulin and helping the body to use insulin effectively. This medicine may sometimes cause side effects such as upper respiratory tract infection, headache, sinus infection, muscle pain and pharyngitis. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

GLIMEPIRIDE-2MG+PIOGLITAZONE-15MG

Manufacturer/Marketer :

FDC Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Zipio G 15mg/2mg Tablet

Zipio G 15mg/2mg Tablet is an oral prescription medication used to lower blood sugar levels in adults with type 2 diabetes. It is prescribed to improve blood sugar control when diet, exercise, and other single medications are not sufficient. Zipio G 15mg/2mg Tablet is not intended for the treatment of type 1 diabetes.

To achieve the best results, you must take Zipio G 15mg/2mg Tablet consistently every day at the same time, exactly as your healthcare provider instructs. It is typically taken once daily with your first main meal of the day to help minimize stomach upset and lower the risk of low blood sugar. Incorporating a balanced diet, routine physical activity, and regular blood sugar monitoring is crucial to support the effectiveness of this treatment.

While taking Zipio G 15mg/2mg Tablet, some people may experience mild side effects, such as headaches, a runny nose, or minor weight gain. However, you must contact your doctor immediately if you experience serious side effects, including sudden swelling in your ankles or feet, rapid weight gain, shortness of breath, or yellowing of your eyes and skin.

Talk to your doctor or pharmacist before starting Zipio G 15mg/2mg Tablet if you have a history of heart failure, liver problems, bladder conditions, or fluid retention. Do not take this if you have severe heart failure, active bladder cancer, or diabetic ketoacidosis.

Zipio G 15mg/2mg Tablet can interact with other substances; for example, alcohol can cause your blood sugar to drop dangerously low, and certain water pills or heart drugs can alter how Zipio G 15mg/2mg Tablet works. If you are pregnant, planning a pregnancy, breastfeeding, or are an older adult, consult your doctor or pharmacist before starting Zipio G 15mg/2mg Tablet to ensure it is safe for you.

Uses of Zipio G 15mg/2mg Tablet

Zipio G 15mg/2mg Tablet is used in the treatment of type 2 diabetes mellitus. The detailed uses of Zipio G 15mg/2mg Tablet are as follows:

  • Type 2 Diabetes Mellitus: Zipio G 15mg/2mg Tablet helps lower blood sugar levels in adults with type 2 diabetes, helping to manage the condition when single-drug therapies, diet, and exercise are not enough.

Key Benefits

Zipio G 15mg/2mg Tablet contains Glimepiride and Pioglitazone.

  • Glimepiride: It helps lower blood sugar by stimulating the pancreas to release more natural insulin. This allows sugar to move from the bloodstream into the body's cells, especially after meals.
  • Pioglitazone: It helps the body's cells respond better to insulin, allowing them to use blood sugar more effectively. It also helps reduce the amount of sugar released by the liver, supporting better long-term blood sugar control.
Side effects of Zipio G 15mg/2mg Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Heart failure needs immediate medical attention. To manage this effect, the doctor's instructions must be followed strictly.
  • Take care of change in your weight as there can be sudden changes.
  • Rest and refrain from physical activity, and restart after a few days.
  • Reduce your salt intake and control your diet with the help of a dietician.
  • Track your symptoms and keep your follow-up appointments to manage severe side effects.

Directions for Use

  • Zipio G 15mg/2mg Tablet should be taken with food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Zipio G 15mg/2mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Zipio G 15mg/2mg Tablet Works

Zipio G 15mg/2mg Tablet contains Glimepiride and Pioglitazone. Glimepiride: It helps lower blood sugar by stimulating the pancreas to release more natural insulin. This allows sugar to move from the bloodstream into the body's cells, especially after meals. Pioglitazone: It helps the body's cells respond better to insulin, allowing them to use blood sugar more effectively. It also helps reduce the amount of sugar released by the liver, supporting better long-term blood sugar control.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Zipio G 15mg/2mg Tablet to avoid unpleasant side-effects.

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Pregnancy

Caution

Zipio G 15mg/2mg Tablet is not generally recommended in pregnancy. It's not clear whether pioglitazone can harm your unborn baby. It is highly recommended to consult your doctor before taking this drug in case you are pregnant.

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Breast Feeding

Caution

It is highly recommended to consult your doctor before taking Zipio G 15mg/2mg Tablet.

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Driving

Caution

Zipio G 15mg/2mg Tablet will not affect your ability to drive or use machines but take care if you experience abnormal vision.

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Liver

Caution

Zipio G 15mg/2mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Zipio G 15mg/2mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

The safety and efficacy of Zipio G 15mg/2mg Tablet in children have not been established. Zipio G 15mg/2mg Tablet is not recommended in children unless prescribed by a child specialist.

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Heart

Consult your doctor

Zipio G 15mg/2mg Tablet is not contraindicated in heart patients. It is often prescribed to reduce the risk of cardiovascular death and hospitalisation for heart failure in adults with type 2 diabetes and established cardiovascular disease.

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Geriatrics

Consult your doctor

While Zipio G 15mg/2mg Tablet is safe to be taken by older patients, it is critical to exercise caution and monitor for potential adverse effects, such as dehydration, low blood pressure, and urinary tract infections, which are more common in older adults.

What if I have taken an overdose of Zipio G 15mg/2mg Tablet

In case of an accidental overdose, seek immediate emergency medical attention. An overdose can cause severe low blood sugar, leading to confusion, extreme sleepiness, sweating, seizures, or loss of consciousness. If you are conscious and suspect your blood sugar is dropping, consume a fast-acting sugar source like fruit juice or glucose tablets while seeking help.

Diet & Lifestyle Advise

  • Follow a balanced diet: Eat a consistent diet rich in fiber, complex carbohydrates, lean proteins, and healthy fats to help maintain stable blood sugar levels.
  • Stay physically active: Engage in moderate daily activities such as walking or cycling to help your body use insulin more effectively and support blood sugar control.
  • Monitor your blood sugar regularly: Check your blood sugar as directed by your doctor and keep a record of your readings to review during medical appointments.
  • Be prepared for low blood sugar: Always carry a fast-acting source of sugar, such as fruit juice, hard candies, or glucose gel, to treat symptoms of low blood sugar promptly.
  • Limit alcohol consumption: Reduce your alcohol intake, as alcohol can interfere with blood sugar control and increase the risk of severe low blood sugar.
health query

Have a query?

How Soon It Starts Working

The time required for Zipio G 15mg/2mg Tablet to start to work: The time required for Zipio G 15mg/2mg Tablet to show its action is unknown. The time for which the effects of Zipio G 15mg/2mg Tablet last: The duration of action for Zipio G 15mg/2mg Tablet is clinically unknown.

What if you forget to take Zipio G 15mg/2mg Tablet

If you miss a dose, take it with your next meal as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular daily schedule. Do not take a double dose to make up for a missed one, as this can cause your blood sugar to drop to a dangerously low level.

Storage

•Store Zipio G 15mg/2mg Tablet at room temperature, ideally between 68°F and 77°F (20°C to 25°C). •Keep the tablets in their original packaging to protect them from moisture and direct light.

Drug Warnings

  • Check your feet every day: Inspect your feet daily for cuts, blisters, sores, or red patches, as diabetes can slow healing and increase the risk of infections.
  • Know the signs of low blood sugar: Some medicines, such as beta-blockers, may mask common symptoms of low blood sugar, including a fast heartbeat or shakiness. Monitor your blood sugar regularly as advised by your doctor.
  • Tell your doctor before medical procedures: Inform your doctor before any planned surgery, medical procedure, or imaging test involving contrast dye, as you may need to temporarily stop taking Zipio G 15mg/2mg Tablet.
  • Carry medical identification: Carry a medical ID card or wear a medical alert bracelet stating that you have type 2 diabetes and are taking Zipio G 15mg/2mg Tablet. This can help healthcare providers provide appropriate treatment during an emergency.

Drug-Drug Interactions

verifiedApollotooltip
  • Other diabetes medicines, insulin, or beta-blockers: Taking these medicines alongside Zipio G 15mg/2mg Tablet may increase the risk of low blood sugar. Your doctor may adjust your treatment or monitor your blood sugar more closely.
  • Corticosteroids, diuretics (water pills), and thyroid medicines: These medicines may increase blood sugar levels and reduce the effectiveness of Zipio G 15mg/2mg Tablet.
  • Antifungal medicines or antibiotics: These medicines may increase the amount of Zipio G 15mg/2mg Tablet in the body, raising the risk of side effects.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid heavy alcohol consumption while taking Zipio G 15mg/2mg Tablet, as it may increase the risk of low blood sugar and affect blood sugar control.
  • Grapefruit and grapefruit juice: Consult your doctor before consuming grapefruit products regularly, as they may affect how your body processes Zipio G 15mg/2mg Tablet.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIDIABETICS]

FAQs

Zipio G 15mg/2mg Tablet is used to treat type 2 (non-insulin-dependent) diabetes mellitus.
Zipio G 15mg/2mg Tablet increases the chances of ovulation even if the woman is at her premenopause stage or not getting her regular periods, so it is advised to use an effective birth control method while taking Zipio G 15mg/2mg Tablet.
Zipio G 15mg/2mg Tablet should not be used in certain medical conditions that include diabetic ketoacidosis (dangerously high blood sugar levels), severe heart failure and active bladder cancer.
Colesevelam may reduce the absorption of Zipio G 15mg/2mg Tablet, so it is advised to take Zipio G 15mg/2mg Tablet at least 4 hours before taking colesevelam.
Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.
Hypoglycemia refers to low blood sugar levels and it is one of the side effects of Zipio G 15mg/2mg Tablet. Hypoglycemia can occur if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with this medicine. It is important to monitor blood sugar levels regularly.
If you have symptoms like increased hunger, increased thirst, frequent urination (usually at night), unexplained weight loss, fatigue, blurred vision, slow wound/sores healing and frequent infections, contact the doctor as it can be a condition of diabetes.
Type 2 diabetes mellitus is a chronic health condition where the body becomes resistant to insulin, a hormone produced by the pancreas that regulates blood sugar levels. As a result, the body either does not produce enough insulin or cannot effectively use the insulin it produces, leading to high blood sugar levels.
Even if your blood sugar levels return to normal, consult your doctor before stopping Zipio G 15mg/2mg Tablet. Sudden stopping medication can cause blood sugar levels to rise again, leading to complications. Follow your doctor's advice to maintain your sugar levels constantly.
Zipio G 15mg/2mg Tablet does not typically cause sleepiness or dizziness as a side effect. In case if you are feeling sleepy or dizzy have some rest after taking it. If you experience persistent sleepy or dizzy, it's advisable to consult your doctor.
Zipio G 15mg/2mg Tablet can be safe for the kidneys when used with caution. If you have a history of kidney diseases or conditions, it's crucial to inform your doctor about your pre-existing and present kidney issues. Your doctor may need to adjust the dosage to ensure safety and effectiveness.
Zipio G 15mg/2mg Tablet is not associated with memory loss as a side effect. However, everyone reacts to medications differently. If you experience memory loss or any other symptoms related to memory, it's important to inform your doctor immediately to find the underlying cause and get appropriate treatment before it worsens.
Taking more than the recommended dose of Zipio G 15mg/2mg Tablet does not provide additional relief and can significantly increase the risk of adverse effects, especially hypoglycemia (low blood sugar).
Yes, Zipio G 15mg/2mg Tablet can cause weight gain. This happens because Zipio G 15mg/2mg Tablet helps the pancreas release more insulin, which can make the body store extra glucose as fat. If you're worried about gaining weight while taking this medication, talk to your doctor. They can help you manage your weight and adjust your treatment if needed
While taking Zipio G 15mg/2mg Tablet avoid foods and drinks like coffee, guar gum, bitter gourd, glucomannan, fenugreek seeds, certain herbs, and alcohol. These can interfere with the medication and affect your blood sugar levels. Always follow your doctor's advice for the best results.
Zipio G 15mg/2mg Tablet is generally considered safe when used as prescribed by a doctor. However, like all medications, it can have side effects and potential interactions with other drugs. It's important to follow your doctor's instructions and inform them of any pre-existing and existing medical conditions or medication history to avoid negative complications.
Yes, people with diabetes can and should have proteins as part of a balanced diet. Proteins help in maintaining muscle mass, repairing tissues, and keeping you full for longer periods, which can help with blood sugar control.
Artificial sweeteners can be a good option for people with diabetes as they add sweetness without raising blood sugar levels. However, it's best to use them in moderation and under your doctor's guidance to avoid negative complications, such as insulin resistance and other metabolic issues. Always follow your healthcare provider's recommendations for the safest use.
Yes, diabetes can cause kidney failure. High blood sugar levels over time can damage the kidneys, making it hard for them to filter waste from the blood. To keep your kidneys healthy with diabetes, manage your blood sugar and blood pressure, and maintain a healthy lifestyle with a balanced diet, regular exercise, and sufficient sleep.
Diabetes currently has no cure, and there is no single medication that can perfectly eliminate the condition. However, it can be effectively managed through a combination of medication, lifestyle modifications, and proper care. Researchers are working to develop new treatments and potential cures.
The common side effects of the Zipio G 15mg/2mg Tablet are headache, sinusitis, myalgia (muscle pain), upper respiratory tract infection, urinary tract infection, diarrhea, nausea, pharyngitis (inflammation of pharynx located back of neck). However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.
It is highly recommended to avoid or strictly limit alcohol. Alcohol can interfere with blood sugar control, increase the risk of severe low blood sugar, and cause other complications. Talk to your doctor or pharmacist about safe limits.
If you experience signs of low blood sugar, such as sweating, shakiness, or dizziness, immediately consume 15 grams of fast-acting sugar, such as a half-cup of fruit juice, three to four glucose tablets, or some hard candy. If your symptoms do not improve, seek medical attention. Talk to your doctor to learn how to prevent these episodes.
Zipio G 15mg/2mg Tablet is generally not recommended during pregnancy or breastfeeding, as alternative treatments are usually preferred to manage blood sugar safely during these times. Talk to your doctor or pharmacist about safe options for you and your baby.
No, Zipio G 15mg/2mg Tablet does not cure type 2 diabetes. It is a daily treatment that helps keep your blood sugar levels controlled. You must continue taking it as prescribed, alongside a healthy diet and lifestyle, to manage your condition effectively.
No, you should take Zipio G 15mg/2mg Tablet with your first main meal of the day. Taking it on an empty stomach significantly increases the risk of experiencing low blood sugar (hypoglycemia) and can cause stomach upset.
Yes, in many cases, you may need to temporarily stop taking Zipio G 15mg/2mg Tablet before surgeries or diagnostic tests that use contrast dyes. Always inform your surgeon, anesthesiologist, or radiologist that you take Zipio G 15mg/2mg Tablet. Talk to your doctor for specific instructions before your procedure.
Long-term use of pioglitazone has been associated with an increased risk of bladder problems in some people. Tell your doctor promptly if you notice blood in your urine, pain while passing urine, or persistent urinary symptoms. Your doctor will decide whether Zipio G 15mg/2mg Tablet remains suitable for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India
Other Info - ZI83788
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