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compositionComposition:METFORMIN-1000MG+TENELIGLIPTIN-20MG
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Prescription Medicine
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Zita-Met 20 mg/1000 mg Tablet is used to treat type 2 diabetes mellitus. It works by decreasing liver glucose production, lowering intestinal glucose uptake and increasing insulin levels in the body. In some cases, this medicine may cause side effects such as nausea, vomiting, diarrhoea, headache, and stomach ache. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METFORMIN-1000MG+TENELIGLIPTIN-20MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zita-Met 20 mg/1000 mg Tablet

Zita-Met 20 mg/1000 mg Tablet is a prescription medicine used to manage type 2 diabetes in adults. It contains metformin and teneligliptin, which work together to lower and control blood sugar levels when diet, exercise, or treatment with a single medicine is not enough. Keeping blood sugar within the target range may help reduce the risk of long-term diabetes-related complications.

Take Zita-Met 20 mg/1000 mg Tablet regularly and exactly as prescribed by your doctor. It is usually taken with or after a meal to help reduce digestive side effects such as nausea or an upset stomach. Continue following the recommended diet and exercise plan, as these are important parts of diabetes management.

Some people may experience nausea, diarrhoea, stomach discomfort, or headache. Low blood sugar may occur when Zita-Met 20 mg/1000 mg Tablet is taken with insulin or certain other diabetes medicines. Seek urgent medical help if you develop severe stomach pain that spreads to the back or symptoms of lactic acidosis, such as unusual tiredness, muscle pain, difficulty breathing, severe weakness, or feeling unusually cold.

Tell your doctor before starting Zita-Met 20 mg/1000 mg Tablet if you have kidney or liver problems, heart failure, severe dehydration, or a serious infection. Do not take this medicine if you have severe kidney impairment, diabetic ketoacidosis, or an allergy to metformin, teneligliptin, or any other ingredient in the medicine.

Tell your doctor about all medicines you take, especially insulin, other diabetes medicines, steroids, diuretics, or blood pressure medicines. Avoid excessive alcohol intake because it may increase the risk of lactic acidosis and affect blood sugar control. If you are pregnant, planning a pregnancy, breastfeeding, or an older adult, consult your doctor before taking this medicine.

Uses of Zita-Met 20 mg/1000 mg Tablet

Your doctor may prescribe Zita-Met 20 mg/1000 mg Tablet to manage the following condition: 

  • Type 2 Diabetes Mellitus: Zita-Met 20 mg/1000 mg Tablet helps lower high blood glucose levels by improving how your body processes insulin and reducing the amount of sugar produced by your liver.

Key Benefits

Taking Zita-Met 20 mg/1000 mg Tablet brings several long-term and daily benefits to help you manage your health safely:

  • Stable Daily Blood Sugar: It helps prevent rapid blood sugar spikes after meals, allowing you to maintain steadier energy levels throughout the day.
  • Protection Against Serious Complications: By keeping your blood sugar within target ranges, it lowers your risk of developing diabetes-related complications, such as kidney damage, nerve pain, and vision loss.
  • Two Treatments in One Tablet: Combining two active therapies into a single daily tablet simplifies your routine, making it easier to stick to your treatment plan.
Side effects of Zita-Met 20 mg/1000 mg Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

  • Zita-Met 20 mg/1000 mg Tablet can be taken with or without food. However, taking it with food may help reduce stomach upset.
  • It is recommended to take Zita-Met 20 mg/1000 mg Tablet once daily or as advised by your doctor.
  • Swallow Zita-Met 20 mg/1000 mg Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Zita-Met 20 mg/1000 mg Tablet Works

Zita-Met 20 mg/1000 mg Tablet contains metformin and teneligliptin, which work in different ways to help control blood sugar levels. Metformin reduces the amount of sugar released by the liver. It also helps the body respond better to insulin, allowing cells to take in and use sugar from the blood more effectively. Teneligliptin belongs to a group of medicines called DPP-4 inhibitors. It increases the activity of natural hormones called incretins, which help the pancreas release more insulin when blood sugar levels are high. These hormones also reduce the amount of sugar released by the liver. Together, metformin and teneligliptin help lower and control blood sugar levels throughout the day.
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Alcohol

Caution

Alcohol may increase the risk of side effects and worsen the condition.

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Pregnancy

Caution

Zita-Met 20 mg/1000 mg Tablet is a category C drug. So, it should be used only when the benefits of this medicine outweigh the risks.

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Breast Feeding

Caution

Zita-Met 20 mg/1000 mg Tablet should not be used in breastfeeding mothers as it may get secreted in the breast milk and cause unwanted effects in the nursing babies.

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Driving

Caution

Zita-Met 20 mg/1000 mg Tablet may cause vision problems. So, do not drive or operate heavy machinery if you have any problems with your vision while using Zita-Met 20 mg/1000 mg Tablet .

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Liver

Caution

Zita-Met 20 mg/1000 mg Tablet should be taken with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Zita-Met 20 mg/1000 mg Tablet should be taken with caution, especially if you have a history of kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Caution

Zita-Met 20 mg/1000 mg Tablet is not recommended for use in children below 18 years of age.

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Heart

Caution

Zita-Met 20 mg/1000 mg Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Zita-Met 20 mg/1000 mg Tablet .

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Geriatrics

Caution

Limited information is available regarding the usage of Zita-Met 20 mg/1000 mg Tablet in elders, so please consult a doctor if you have any concerns.

What if I have taken an overdose of Zita-Met 20 mg/1000 mg Tablet

If you suspect an overdose, seek emergency medical care immediately. An overdose can cause dangerously low blood sugar or a serious medical emergency called lactic acidosis, which requires urgent treatment in a hospital.

Diet & Lifestyle Advise

  • Manage Carb Intake: Focus on complex, low-glycaemic carbohydrates like leafy greens, whole grains, and legumes to avoid sharp blood sugar spikes after meals.
  • Exercise Regularly: Aim for 150 minutes of moderate physical activity (such as brisk walking) per week. Muscle movement helps your body use insulin more efficiently.
  • Monitor Your Sugar Levels: Keep a regular log of your blood sugar levels as advised by your doctor to help track how your body responds to the medicine.
  • Limit Alcohol Consumption: Restrict alcohol intake because it can cause sudden drops in blood sugar and significantly increase your risk of lactic acidosis.

Health Queries

What are the alternative or substitute medicines available for Zita-Met?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Zita-Met is a combination of two active ingredients: sitagliptin and metformin, which are used to manage type 2 diabetes. If you are looking for alternatives, you can safely use any equivalent medication that contains this exact same generic combination of sitagliptin and metformin in the same strengths. There are many high-quality, widely available options with these identical active ingredients. However, please consult your prescribing doctor before making any changes, as they will ensure the transition is smooth and the dosage remains correct for your specific health needs.

I have diabetes with high blood sugar levels and am experiencing skin problems. What medications or creams should I use to treat this?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

It is very common to experience skin issues when blood sugar levels are high, as diabetes can cause dry skin and make you more prone to infections. The most important step is working with your doctor to manage your blood sugar. For dry or itchy skin, apply a fragrance-free moisturising cream containing urea or ceramide daily. If you have a fungal infection (common in skin folds), an over-the-counter antifungal cream like clotrimazole or miconazole can help. For bacterial infections, a prescription antibiotic ointment like mupirocin might be needed. Please consult your doctor or a dermatologist for a proper diagnosis before starting these treatments.

I have high blood pressure and type 2 diabetes. Can I start taking BGR 34 tablets, and if so, what is the recommended dosage? Also, what are the suitable substitutes for Zita Met tablets?

G.santoshini Reddy

G.santoshini Reddy

M Pharmacy (Pharmaceutics)

Regarding the herbal supplement you mentioned, it can help manage blood sugar, but you must consult your doctor before starting it to avoid low blood sugar (hypoglycemia) or interactions with your blood pressure medications. A typical dose is two tablets twice daily, but your physician should confirm this. For your current prescription tablet, which contains the active combination of sitagliptin and metformin, you can substitute it with any equivalent generic combination of sitagliptin and metformin of the same strength. Please consult your doctor before making any changes to your medication regimen.
health query

Have a query?

How Soon It Starts Working

The time required for Zita-Met 20 mg/1000 mg Tablet to start to work: Zita-Met 20 mg/1000 mg Tablet starts to show its action within 1 to 2 hours of administration. The time for which the effects of Zita-Met 20 mg/1000 mg Tablet last: Zita-Met 20 mg/1000 mg Tablet effect lasts for 24 hours.

What if you forget to take Zita-Met 20 mg/1000 mg Tablet

If you miss a dose, take it as soon as you remember with food. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Zita-Met 20 mg/1000 mg Tablet tablets at controlled room temperature, ideally between 15°C and 30°C. •Keep the tablets inside their original blister packaging until you are ready to take them, as this protects them from moisture and direct light.

Drug Warnings

  • Check the packaging: Make sure the blister strip is intact. Do not take the tablet if the packaging is damaged or the tablet looks different from usual.
  • Carry a quick source of sugar: Keep glucose tablets, glucose gel, or fruit juice with you, especially if you also take insulin or other medicines that may cause low blood sugar.
  • Inform your healthcare team before surgery: Tell your doctor, dentist, or surgeon that you are taking Zita-Met 20 mg/1000 mg Tablet before any planned procedure. They will advise whether you need to stop taking it temporarily.
  • Tell your doctor before a contrast scan: Inform your doctor if you are having an X-ray, CT scan, or another imaging test that uses an injected contrast dye. Depending on your kidney function and the type of procedure, you may need to stop Zita-Met 20 mg/1000 mg Tablet temporarily and restart it only after your doctor confirms that it is safe.
  • Take care when driving: Zita-Met 20 mg/1000 mg Tablet does not usually affect driving when taken alone. However, low blood sugar may occur when it is used with insulin or certain other diabetes medicines. Do not drive or operate machinery if you feel dizzy, shaky, weak, confused, or unable to concentrate.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Zita-Met 20 mg/1000 mg Tablet and require closer monitoring or dose adjustments:

  • Other diabetes medications: Taking this medicine with insulin or sulfonylureas may increase the risk of low blood sugar.
  • Diuretics and steroids: Water pills and corticosteroids can raise your blood sugar, making this medicine less effective.
  • Beta-blockers: These blood pressure medicines can mask warning signs of low blood sugar, such as a rapid heart rate or palpitations.
Teneligliptin + MetforminIodixanol
Critical
Teneligliptin + MetforminIopamidol
Critical

Drug-Drug Interactions

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Teneligliptin + MetforminIodixanol
Critical
How does the drug interact with Zita-Met 20 mg/1000 mg Tablet:
Co-administration of iodixanol with Zita-Met 20 mg/1000 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Zita-Met 20 mg/1000 mg Tablet and iodixanol, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Teneligliptin + MetforminIopamidol
Critical
How does the drug interact with Zita-Met 20 mg/1000 mg Tablet:
Co-administration of Iopamidol with Metformin can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between metformin and iopamidol, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Teneligliptin + MetforminIodamide
Critical
How does the drug interact with Zita-Met 20 mg/1000 mg Tablet:
Co-administration of Zita-Met 20 mg/1000 mg Tablet with iodamide can increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Zita-Met 20 mg/1000 mg Tablet and iodamide, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Teneligliptin + MetforminGatifloxacin
Critical
How does the drug interact with Zita-Met 20 mg/1000 mg Tablet:
Co-administration of Zita-Met 20 mg/1000 mg Tablet with gatifloxacin can cause both hypoglycemia (low blood glucose) and, less frequently, hyperglycemia (high blood glucose).

How to manage the interaction:
Although there is an interaction between Zita-Met 20 mg/1000 mg Tablet and gatifloxacin, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience headache, dizziness, sleepiness, nervousness, confusion, tremors (shaking of hands and legs), hunger, weakness, sweating, or fast heartbeats. Do not discontinue without consulting a doctor.
Teneligliptin + MetforminMetrizamide
Critical
How does the drug interact with Zita-Met 20 mg/1000 mg Tablet:
Co-administration of Zita-Met 20 mg/1000 mg Tablet and metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Although there is an interaction between Zita-Met 20 mg/1000 mg Tablet and metrizamide, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Teneligliptin + MetforminIomeprol
Critical
How does the drug interact with Zita-Met 20 mg/1000 mg Tablet:
Co-administration of iomeprol with Zita-Met 20 mg/1000 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between metformin and Zita-Met 20 mg/1000 mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Teneligliptin + MetforminIopromide
Critical
How does the drug interact with Zita-Met 20 mg/1000 mg Tablet:
Co-administration of iopromide with Zita-Met 20 mg/1000 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between iopromide and Zita-Met 20 mg/1000 mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Teneligliptin + MetforminTopiramate
Severe
How does the drug interact with Zita-Met 20 mg/1000 mg Tablet:
Coadministration of Zita-Met 20 mg/1000 mg Tablet and topiramate may increase the risk of lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is an interaction between Zita-Met 20 mg/1000 mg Tablet and topiramate, it can be taken if prescribed by a doctor. However, if you experience weakness, muscle pain, fatigue, less desire to eat, slow or irregular heartbeat, breathing difficulty, or chills, consult a doctor immediately. Do not stop using any medication without a doctor's advice.
Teneligliptin + MetforminAcetazolamide
Severe
How does the drug interact with Zita-Met 20 mg/1000 mg Tablet:
Co-administration of Zita-Met 20 mg/1000 mg Tablet with Acetazolamide may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Although there is an interaction between Zita-Met 20 mg/1000 mg Tablet and acetazolamide, they can be taken together if prescribed by a doctor. However, if you experience weakness, muscle pain, difficulty breathing, dizziness, chest pain or discomfort, fatigue, or less desire to eat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Teneligliptin + MetforminEthanol
Severe
How does the drug interact with Zita-Met 20 mg/1000 mg Tablet:
Co-administration of Zita-Met 20 mg/1000 mg Tablet with Ethanol may increase the risk of Lactic acidosis (excessive lactic acid production in blood).

How to manage the interaction:
Although there is an interaction between Zita-Met 20 mg/1000 mg Tablet and Ethanol, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience weakness, muscle pain, increased drowsiness, dizziness, stomach pain or discomfort, slow or irregular heartbeat difficulty in breathing, or less desire to eat, contact a doctor immediately. Do not stop using any medications without a doctor’s advice.

Drug-Food Interactions

verifiedApollotooltip

Certain foods or drinks may affect the safety or tolerability of Zita-Met 20 mg/1000 mg Tablet . Important interactions include:

  • Alcohol: Avoid heavy drinking while taking this medicine. Alcohol increases the danger of lactic acidosis and can cause unpredictable shifts in blood sugar.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIDIABETICS AND ANTIHYPERGLYCEMICS]

FAQs

Zita-Met 20 mg/1000 mg Tablet is used to treat Type 2 diabetes mellitus. It improves glycaemic control in diabetic patients who do not react well to Metformin alone.
Zita-Met 20 mg/1000 mg Tablet is a combination of two antidiabetic medicines, Metformin and Teneligliptin. It works by increasing insulin production, helping to restore your body's appropriate response to insulin, especially in muscle and fatty tissues, thereby lowering your elevated blood sugar levels.
Hypoglycemia refers to low blood glucose levels. Zita-Met 20 mg/1000 mg Tablet may cause hypoglycemia. Hypoglycemia can occur if you miss or delay your food, drink alcohol, engage in intense exercise, or take other antidiabetic medicine along with this medicine. So, take your medicine as advised by your doctor to avoid any unwanted effects of this medicine.
If you feel that your blood sugar levels are dropping, eat glucose tablets or chocolate immediately. This will help to increase your sugar levels instantly. So, it is always advised to carry glucose tablets or sugar candies with you.
Yes, Zita-Met 20 mg/1000 mg Tablet is safe to use if taken in the dose and duration prescribed by the doctor.
Zita-Met 20 mg/1000 mg Tablet may cause nausea and vomiting as side effects. Consume bland food and water, avoid foods with strong smells, spicy food, caffeine, alcohol and carbonated drinks.
Zita-Met 20 mg/1000 mg Tablet is contraindicated in people who are allergic to any of its components, patients having severe ketoacidosis, diabetic coma or pre-coma, type 1 diabetes, severe infection, severe trauma and severe external injury and in patients with a history of lactic acidosis.
Zita-Met 20 mg/1000 mg Tablet can cause lactic acidosis, a rare but serious metabolic complication. Consult the doctor if you notice symptoms of lactic acidosis like abdominal pain, vomiting, muscle cramps, difficulty breathing, reduced body temperature and heartbeat, and severe tiredness.
Long-term use of Zita-Met 20 mg/1000 mg Tablet may lead to vitamin B12 deficiency as Zita-Met 20 mg/1000 mg Tablet might interfere with the absorption of vitamin B12. Consult the doctor if you experience symptoms of vitamin B12 deficiency like tingling sensations and numbness in hands and feet, urinary problems, weakness, change in mental status and difficulty in maintaining balance.
Store Zita-Met 20 mg/1000 mg Tablet at room temperature, in a dry place. Keep it out of sight and reach of children.
Zita-Met 20 mg/1000 mg Tablet is not recommended during pregnancy as its safety in pregnant women is unknown. Contact the doctor if you are pregnant, planning for pregnancy or think you may be pregnant.
Zita-Met 20 mg/1000 mg Tablet is not recommended for nursing mothers as this medicine may get secreted in the breast milk and cause unwanted effects in the nursing babies. Contact the doctor if you are breastfeeding.
Zita-Met 20 mg/1000 mg Tablet is not recommended for use in children below 18 years of age.
Overdose of Zita-Met 20 mg/1000 mg Tablet might cause lactic acidosis. Symptoms of lactic acidosis may include nausea, vomiting, and weakness. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.
Side effects of Zita-Met 20 mg/1000 mg Tablet include nausea, vomiting, diarrhoea, headache, stomach ache, respiratory infection, weight gain, sweating, palpitations, and vision problems. Consult the doctor if any of the side effects persist or worsen.
Consult the doctor if you have severe joint pain after taking Zita-Met 20 mg/1000 mg Tablet . The doctor might ask you to discontinue the medicine if appropriate.
Take Zita-Met 20 mg/1000 mg Tablet with or after a meal unless your doctor advises otherwise. Taking it with food may help reduce nausea, stomach discomfort, and other digestive side effects. Contact your doctor if these symptoms continue or become difficult to manage.
Zita-Met 20 mg/1000 mg Tablet is generally considered weight-neutral, meaning it usually does not cause significant weight gain. However, changes in weight may vary between individuals. Continue following the diet and physical activity plan recommended by your healthcare team.
Type 2 diabetes usually requires long-term treatment. Continue taking Zita-Met 20 mg/1000 mg Tablet for as long as your doctor recommends, even if you feel well, because high blood sugar may not cause noticeable symptoms. Do not stop taking the medicine without consulting your doctor.
If you are pregnant, planning a pregnancy, or breastfeeding, consult your doctor before taking Zita-Met 20 mg/1000 mg Tablet . Your doctor will recommend the most suitable treatment based on your blood sugar levels and individual health needs.
Zita-Met 20 mg/1000 mg Tablet does not usually affect the ability to drive. However, low blood sugar may occur when it is taken with insulin or certain other diabetes medicines. Do not drive if you feel dizzy, shaky, weak, confused, or unable to concentrate.
No. Zita-Met 20 mg/1000 mg Tablet helps control blood sugar but does not cure type 2 diabetes. Taking the medicine regularly and following your recommended diet, physical activity, and blood sugar monitoring plan can help manage the condition and reduce the risk of complications.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai €“ 400 026.
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