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  3. Zivofen XlTablet 10's

Zivofen XlTablet 10's, Pack of 10
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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Zivofen XlTablet is used to relieve pain and inflammation associated with various medical conditions, including osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, and bone and joint pain. It consists of Diclofenac (Diclofenac Potassium), Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes. Thus, it reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.

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Composition :

DICLOFENAC-50MG + PARACETAMOL-325MG + TRYPSIN CHYMOTRYPSIN-50000AU

Manufacturer/Marketer :

Vinayak Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zivofen XlTablet

Zivofen XlTablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, and bone and joint pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis, also known as joint inflammation, is the tenderness and swelling of the joints. Symptoms include swelling, pain, and stiffness. 

Zivofen XlTablet consists of Diclofenac (Diclofenac Potassium), Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes. Thus, it reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.

Zivofen XlTablet should be taken as prescribed by your doctor.  Sometimes it may cause certain common side effects such as nausea, vomiting, stomach pain, loss of appetite, indigestion, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Zivofen XlTablet may cause drowsiness and dizziness, so drive with caution. Zivofen XlTablet is not recommended for children as safety and efficacy have not been established. Avoid consuming alcohol with Zivofen XlTablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any interactions. It is advised not to take more than the prescribed dose of medicine and for a longer period. 

Uses of Zivofen XlTablet

Treatment of Pain and inflammation associated with musculoskeletal and joint disorders

Directions for Use

• It is recommended to take Zivofen XlTablet with food to prevent stomach upset, or as advised by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow Zivofen XlTablet as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

Zivofen XlTablet is a combination of three drugs, namely: Diclofenac, Paracetamol, and Trypsin chymotrypsin. Zivofen XlTablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Diclofenac is an NSAID (Non-Steroidal Anti-Inflammatory Drug) and Paracetamol is an analgesic. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes, thereby reducing mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin is a combination of enzymes that breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation by increasing the blood supply at the affected area.

How Zivofen XlTablet Works

Zivofen XlTablet consists of Diclofenac (Diclofenac Potassium), Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers called prostaglandins by inhibiting cyclooxygenase (COX) enzymes. Thus, it reduces mild to moderate pain and inflammation at the injured or damaged site. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.

Storage

• Store in a cool and dry place away from sunlight.• Keep Zivofen XlTablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Zivofen XlTablet

Please do not exceed the recommended dose, as it might cause an overdose. Signs and symptoms of an overdose of Zivofen XlTablet may include abdominal pain, bloody, black, or tarry stools, coma and death, drowsiness, liver problems, loss of consciousness, nausea, seizures, slow, shallow, or irregular breathing, stomach pain, and vomiting. Seek immediate medical attention if you observe any symptoms or think you have taken too much. Do this even if there are no signs of discomfort or poisoning.

Drug Warnings

Avoid taking Zivofen XlTablet if you are allergic to any of its contents; if you have/had severe heart problems, active or recurring peptic ulcer, gastrointestinal perforation, bleeding problems, inflammation of intestines, or severe liver or kidney impairment. Inform your doctor if you have/had high blood pressure, heart problems, high cholesterol, diabetes, asthma, angina, bowel problems, a habit of smoking, or liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Stop taking Zivofen XlTablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. This medicine is not recommended for use in children as safety is not established. It is advised not to take more than the prescribed dose of Zivofen XlTablet for a prolonged period.

Diet & Lifestyle Advise

  • Physical activity helps strengthen muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
  • Avoid smoking and alcohol consumption.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.

Habit Forming

No

Therapeutic Class

ANALGESICS

Zivofen XlTablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zivofen XlTablet as it may increase drowsiness. It may also increase the risk of stomach bleeding.

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Pregnancy

Caution

Inform your doctor if you are pregnant or planning pregnancy before taking Zivofen XlTablet . Your doctor may prescribe this medicine if the benefits outweigh the risks

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Breast Feeding

Caution

Inform your doctor if you are breastfeeding before taking Zivofen XlTablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Zivofen XlTablet may cause dizziness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have liver problems. Dose adjustment may be needed. Zivofen XlTablet is not recommended for patients with severe hepatic impairment.

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Kidney

Caution

Please consult your doctor if you have kidney impairment. Dose adjustment may be needed. Zivofen XlTablet is not recommended for patients with severe renal impairment.

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Children

Unsafe

Zivofen XlTablet is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

Zivofen XlTablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, and bone and joint pain.

Zivofen XlTablet contains Diclofenac, Paracetamol, and Trypsin chymotrypsin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Trypsin chymotrypsin breaks down the abnormal proteins at the site of inflammation, thereby reducing swelling and inflammation.

Do not take any other medicines for pain relief, such as NSAIDs along with Zivofen XlTablet , unless prescribed by a doctor, as it might increase the risk of side effects.

Avoid exceeding the dose and duration advised by the doctor. Taking more than the daily dose of Zivofen XlTablet might cause serious liver damage or allergic reactions like rash, difficulty breathing, and swelling of the face, throat, and mouth. Therefore, Zivofen XlTablet should not be taken for longer durations unless prescribed by the doctor.

Country of origin

India

Manufacturer/Marketer address

115, Atlanta Estate, Off. Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - ZIV0053

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:03 AM IST

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Reference

  1. https://www.indiamart.com/proddetail/trypsin-chymotrypsin-diclofenac-potassium-and-paracetamol-tablets-24658331512.htmlhttp://www.welltechpharma.com/productdetail.php?item=27
  2. https://www.snubiocare.in/product/diclofenac-potassium-50-mg-trypsin-chymotrypsin-50000-au-paracetamol-325-mg/
  3. https://www.merohealthcare.com/childcategory/diclofenac-trypsin-chymotrypsin

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