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compositionComposition:DICLOFENAC-50MG+SERRATIOPEPTIDASE-10MG
prescriptionPrescription Medicine
Zocxafen Tablet

Zocxafen Tablet is used in the reduction of pain and inflammation related to conditions such as bone or soft tissue injuries, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, migraine and tension headaches, and menstrual pain (dysmenorrhea). It helps relieve pain and swelling in the affected tissues by blocking certain chemicals that cause pain and breaking down insoluble proteins (fibrin) in blood clots. It also supports faster healing by promoting the drainage of excess fluid from swollen tissues.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DICLOFENAC-50MG+SERRATIOPEPTIDASE-10MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Zocxafen Tablet

Zocxafen Tablet is used in the treatment of pain and inflammation associated with various conditions, such as bone or soft tissue injuries, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, migraine and tension headaches, and menstrual pain (dysmenorrhea).

Zocxafen Tablet contains Diclofenac and Serratiopeptidase. Diclofenac blocks the action of a chemical messenger (cyclo-oxygenase) that causes pain and swelling at the injured or damaged tissue. Serratiopeptidase helps degrade insoluble protein (fibrin) in blood clots and thin fluids in the affected area, thereby reducing swelling.

Take Zocxafen Tablet exactly as prescribed by your doctor. Swallow it whole with a glass of water; do not crush, chew, or break it. Zocxafen Tablet may cause common side effects such as stomach ache, diarrhoea, nausea (feeling sick), and indigestion. Please consult your doctor if the side effects persist or worsen.

Do not take Zocxafen Tablet if you are allergic to any of its ingredients or to other painkillers such as aspirin, ibuprofen, naproxen, or diclofenac. Avoid taking Zocxafen Tablet during the last trimester of pregnancy unless advised by your doctor. It is not recommended for use in children. Do not take Zocxafen Tablet if you have a stomach ulcer, gastric bleeding, severe heart failure, stroke, or hypertension (high blood pressure).

Uses of Zocxafen Tablet

Zocxafen Tablet is used in the treatment of pain. The detailed uses of Zocxafen Tablet are as follows:

  • Reduction of pain and inflammation: Zocxafen Tablet helps relieve pain and swelling associated with various conditions, including bone or soft-tissue injuries, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, migraine and tension headaches, and menstrual pain (dysmenorrhea).

Key Benefits

Zocxafen Tablet offers the following medicinal benefits:

  • Effectively reduces musculoskeletal pain from conditions such as back pain, arthritis, spondylitis, and muscle injuries.
  • Relieves pain and swelling after surgeries, sprains, fractures, and other soft-tissue injuries.
  • Helps manage pain associated with toothaches, dental procedures, sore throat, and ear infections.
  • Supports healing by promoting fluid drainage from swollen tissues, helping inflammation decrease more quickly.
Side effects of Zocxafen Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Directions for Use

  • Zocxafen Tablet can be taken with or without food. However, taking it with food may help reduce stomach upset.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Zocxafen Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Zocxafen Tablet Works

Zocxafen Tablet contains two medications: Diclofenac and Serratiopeptidase. • Diclofenac: It is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the action of a chemical messenger (cyclo-oxygenase) responsible for causing pain and swelling at the injured or damaged tissue. • Serratiopeptidase: It is a proteolytic enzyme that helps break down insoluble protein (fibrin) in blood clots and thins fluids in the affected area, making it easier for excess fluid to drain and helping to reduce swelling. • Together, these medications help relieve pain and inflammation.
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Alcohol

Caution

You are recommended not to consume alcohol along with Zocxafen Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Please inform your doctor if you are pregnant or planning to become pregnant before taking Zocxafen Tablet.

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Breast Feeding

Caution

Zocxafen Tablet may enter breast milk. Consult your doctor for more information on this if you are a breastfeeding mother.

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Driving

Caution

Zocxafen Tablet may impair driving, as it can cause dizziness. Drive or operate machinery only when you are alert.

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Liver

Caution

Zocxafen Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Zocxafen Tablet to be taken with caution if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Caution

Zocxafen Tablet is not recommended for children under 10 years of age. For them, the dose must be adjusted and recommended only by a child specialist.

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Heart

Unsafe

Zocxafen Tablet should be avoided in cardiac patients, as it can lead to serious cardiovascular risks

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Geriatrics

Caution

Zocxafen Tablet should be used with caution in geriatric patients, as it can cause serious side effects.

What if I have taken an overdose of Zocxafen Tablet

Do not take more than the prescribed dose of Zocxafen Tablet, as it may cause serious side effects or poisoning. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

Dietary supplements:

  • Include supplements rich in glucosamine, chondroitin sulphate, vitamin D, and calcium.
  • Turmeric and fish oils can help reduce inflammation in the tissues.

Anti-inflammatory foods:

  • Include fatty fish like salmon, trout, tuna, and sardines in your diet. These are rich in omega-3 fatty acids that help reduce inflammation.

Physical activity:

  • Avoid heavy exercise, as it may exacerbate joint pain in arthritis.
  • Focus on stretching and low-impact aerobic exercise, such as walking on a treadmill, cycling, or swimming.
  • Strengthen muscles with light weightlifting to support joint health.

Posture and sitting habits:

  • Avoid prolonged sitting; keep sitting periods short (10-15 minutes).
  • Use back support, such as a rolled-up towel, to maintain the natural curve of your spine.
  • Keep your knees and hips at right angles while sitting.
  • Use a footrest if needed to reduce strain.

Have a query?

How Soon It Starts Working

  • The time required for Zocxafen Tablet to start to work: The time required for Zocxafen Tablet to start to work is 15 to 20 minutes after administration.
  • The time for which the effects of Zocxafen Tablet last: The effect of Zocxafen Tablet lasts for 8 hours.

What if you forget to take Zocxafen Tablet

If you miss a dose of Zocxafen Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Do not take Zocxafen Tablet if you are allergic to any of its ingredients or to other painkillers such as aspirin, ibuprofen, naproxen, or diclofenac.
  • Avoid taking Zocxafen Tablet during the last trimester of pregnancy unless advised by your doctor.
  • Zocxafen Tablet is not recommended for use in children.
  • Do not take Zocxafen Tablet if you have a stomach ulcer, gastric bleeding, severe heart failure, stroke, or hypertension (high blood pressure).
  • Do not drive or operate heavy machinery after intake of Zocxafen Tablet, as it may cause dizziness.
  • Patients who have recently undergone heart bypass surgery should take Zocxafen Tablet with caution and only under medical supervision.
  • Use of Zocxafen Tablet is contraindicated in patients with kidney failure or those undergoing dialysis.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Zocxafen Tablet may interact with certain medicines, potentially increasing side effects or altering their effectiveness. Inform your doctor if you are taking any of the following:

  • Nonsteroidal anti-inflammatory drugs (Meloxicam, Tolmetin, Flurbiprofen)
    • Potential effect: May increase the risk or severity of gastrointestinal side effects like stomach bleeding and ulcers.
  • Immunosuppressants (Tacrolimus)
    • Potential effect: May increase the risk of kidney problems.
  • Anti-HIV drugs (Tenofovir disoproxil, Tenofovir alafenamide)
    • Potential effect: May increase the risk of kidney problems.
  • Anti-cancer drugs (Dasatinib, Ramucirumab)
    • Potential effect: May increase the risk of bleeding.
  • Blood thinners (Dabigatran etexilate)
    • Potential effect: May increase the risk of stomach bleeding.

Drug-Food Interactions: Avoid drinking alcohol during treatment with Zocxafen Tablet, as it may cause unpleasant effects and increase the risk of liver damage.

Drug-Disease Interactions: Zocxafen Tablet should be avoided or used with caution in people with:

  • Stomach bleeding and ulcers
  • Severe heart failure
  • Stroke
  • Inflammatory bowel disease (such as ulcerative colitis and Crohn's disease)
  • Hypertension (high blood pressure)
  • Alcoholism
DiclofenacMeloxicam
Critical
DiclofenacDalteparin
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Zocxafen Tablet:
Co-administration of Zocxafen Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Zocxafen Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacDalteparin
Severe
How does the drug interact with Zocxafen Tablet:
Co-administration use of Zocxafen Tablet with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Zocxafen Tablet may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.
DiclofenacValdecoxib
Severe
How does the drug interact with Zocxafen Tablet:
Taking Valdecoxib with Zocxafen Tablet may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Zocxafen Tablet and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacSirolimus
Severe
How does the drug interact with Zocxafen Tablet:
Co-administration of Zocxafen Tablet with Sirolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Zocxafen Tablet and Sirolimus can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
DiclofenacEnoxaparin
Severe
How does the drug interact with Zocxafen Tablet:
Taking Zocxafen Tablet with Enoxaparin can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Zocxafen Tablet and Enoxaparin, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
DiclofenacFondaparinux
Severe
How does the drug interact with Zocxafen Tablet:
Coadministration of Zocxafen Tablet with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Zocxafen Tablet and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacTenofovir disoproxil
Severe
How does the drug interact with Zocxafen Tablet:
Co-administration of Zocxafen Tablet with tenofovir disoproxil may increase the risk of developing kidney problems.

How to manage the interaction:
There may be a possible interaction between Zocxafen Tablet and Tenofovir disoproxil but they can be taken together if your doctor has prescribed them. However consult your doctor immediately if you experience symptoms such as such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacDasatinib
Severe
How does the drug interact with Zocxafen Tablet:
Taking Dasatinib together with Zocxafen Tablet may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Zocxafen Tablet and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.
DiclofenacHuman immunoglobulin
Severe
How does the drug interact with Zocxafen Tablet:
Taking Zocxafen Tablet with human immunoglobulin may increase the risk of kidney problems.

How to manage the interaction:
Although there is an interaction between Human immunoglobulin and Zocxafen Tablet, you can take these medicines together if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
DiclofenacLomitapide
Severe
How does the drug interact with Zocxafen Tablet:
Taking Zocxafen Tablet with Lomitapide will have an additive effect and may cause liver problems.

How to manage the interaction:
There may be a possible interaction between Zocxafen Tablet and Lomitapide, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark colored urine, light colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

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Therapeutic Class

[ANALGESICS]

FAQs

Zocxafen Tablet is used in the treatment of pain and inflammation associated with various conditions, such as bone or soft tissue injuries, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, dental pain, migraine and tension headaches, and menstrual pain (dysmenorrhea).

Zocxafen Tablet when taken by patients who are allergic to painkillers can be harmful. It should also be avoided in people with a history of heart failure, kidney or liver disease, stomach ulcers and high blood pressure.

You should take Zocxafen Tablet only if the doctor has prescribed it. The maximum recommended dose of Zocxafen Tablet is twice daily. Zocxafen Tablet can be one in the morning and one in the evening.

Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation and pain in the joints.

Ankylosing spondylitis is an arthritis of the spine that can lead to the fusion of the vertebrae, leading to pain and inflammation in the spine.

Yes, Zocxafen Tablet can cause stomach upset. It should preferably be taken with food to avoid it.

Zocxafen Tablet should be stored in a cool and dry place, away from direct sunlight. Keep the medicine out of reach of children.

Zocxafen Tablet is generally safe when used as directed by your physician for short-term relief of pain and inflammation. However, you should not use Zocxafen Tablet if you have a stomach ulcer, gastric bleeding, severe heart failure, stroke, hypertension (high blood pressure), kidney failure, or if you are undergoing dialysis.

Yes, you can stop taking Zocxafen Tablet once your pain is relieved, but only after consulting your doctor. It is recommended to follow your doctor's advice on the duration and dosage of Zocxafen Tablet, as stopping the medication too early could affect your recovery.

Yes, the use of Zocxafen Tablet can cause nausea and vomiting as side effects. Taking it with food may help prevent nausea. If you experience vomiting, try drinking small sips of water or other fluids frequently. If these symptoms persist, please consult your doctor.

Yes, the use of Zocxafen Tablet may cause dizziness as a side effect in some individuals. Avoid driving or operating machinery if you experience dizziness. If dizziness persists, please consult your doctor.

Yes, Zocxafen Tablet is contraindicated in patients who are allergic to any of its components, those with kidney failure, or those undergoing dialysis. It should not be taken by patients with a stomach ulcer, gastric bleeding, severe heart failure, stroke, or hypertension (high blood pressure). Also, it should be avoided during the last trimester of pregnancy. Please consult your doctor if you have any concerns while using Zocxafen Tablet.

No, Zocxafen Tablet is not generally recommended for stomach pain. In fact, it may cause stomach upset, ulcers, or bleeding. If you have stomach pain, please consult your doctor for a proper diagnosis and treatment.

Yes, long-term or high-dose use of Zocxafen Tablet, a nonsteroidal anti-inflammatory drug (NSAID), can potentially damage the kidneys. Regular monitoring and caution are advised when using Zocxafen Tablet, especially in individuals with existing kidney disease. Please consult your doctor before using Zocxafen Tablet.

Yes, Zocxafen Tablet can be taken on an empty stomach, but it is generally advisable to take Zocxafen Tablet with food to reduce the risk of side effects. Always follow your doctor's instructions when taking Zocxafen Tablet.

Zocxafen Tablet is generally not recommended for children under 10 years of age unless prescribed by a doctor. Always consult a paediatrician before giving Zocxafen Tablet to a child, as the dosage may need to be adjusted for them.

Zocxafen Tablet is intended for short-term use only, as it may cause side effects, including gastrointestinal or cardiovascular adverse effects. Always follow your doctor's advice regarding the duration and dosage.

No, it is generally not recommended to consume alcohol while taking Zocxafen Tablet as it may increase the risk of side effects, such as stomach irritation, ulcers, and bleeding. Your doctor may advise you to limit or avoid alcohol consumption while taking Zocxafen Tablet.

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Country of origin

India

Manufacturer/Marketer address

Chittoor, Andhra Pradesh
Other Info - ZO20331
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