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compositionComposition:CEFOPERAZONE-500MG+SULBACTAM-500MG
prescriptionPrescription Medicine
Zofactum-1Gm Inj

Zofactum-1Gm Inj is used to treat various bacterial infections of the lungs, urinary tract, blood, brain and spinal cord (meningitis), skin, abdomen, bones, joints, and certain sexually transmitted infections like gonorrhoea. It works by inhibiting the growth of pathogenic bacteria, thereby reducing fever, pain, and inflammation and clearing the infection.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

CEFOPERAZONE-500MG+SULBACTAM-500MG

Manufacturer/Marketer :

Elder Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zofactum-1Gm Inj

Zofactum-1Gm Inj is a combination medicine used to treat various bacterial infections such as respiratory tract (lungs) infection, urinary infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body.

Zofactum-1Gm Inj contains Cefoperazone and Sulbactam, which work together to treat bacterial infections. It helps control the spread of infection and lowers symptoms. This supports quicker healing and reduces the risk of complications. Together, Zofactum-1Gm Inj helps the body recover from bacterial infections effectively.

Your doctor administers Zofactum-1Gm Inj. You may experience nausea, vomiting, diarrhoea and rash. Most of these side effects do not require medical attention. However, talk to your doctor if you experience these side effects persistently.

Inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Consult your doctor before taking Zofactum-1Gm Inj if you are pregnant or planning a pregnancy. Avoid taking Zofactum-1Gm Inj if you are breastfeeding, as Zofactum-1Gm Inj may pass into breast milk.

Uses of Zofactum-1Gm Inj

Zofactum-1Gm Inj is used in the treatment of bacterial infections. The detailed uses of Zofactum-1Gm Inj are as follows:

  • Treatment of Bacterial Infections: Zofactum-1Gm Inj is effective against a wide range of bacterial infections, including those affecting the respiratory tract, urinary tract, skin, and soft tissues.
  • Management of Intra-Abdominal Infections: Zofactum-1Gm Inj is used to treat severe intra-abdominal infections, such as peritonitis and abscesses.
  • Septicemia Treatment: Zofactum-1Gm Inj is prescribed for managing septicemia, a life-threatening condition caused by harmful bacteria in the bloodstream.
  • Bone and Joint Infections: Zofactum-1Gm Inj is also used in treating severe infections of bones and joints, such as osteomyelitis and septic arthritis.

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Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to improve effectiveness.
  • Zofactum-1Gm Inj will be administered by a healthcare professional.
  • Do not self-administer it.

Key Benefits

  • Helps treat infections affecting the lungs, urine, blood, skin, abdomen, bones, and joints.
  • Management of serious infections such as meningitis (infection of the brain and spinal cord) and gonorrhoea (sexually transmitted infection).
  • Helps kill harmful bacteria and limits their growth.
  • Reduces symptoms such as fever, pain, swelling, and discomfort.
  • Helps prevent the infection from spreading to other body parts.

How Zofactum-1Gm Inj Works

Zofactum-1Gm Inj contains Cefoperazone and Sulbactam. • Cefoperazone kills bacteria by inhibiting the synthesis of their protective outer layer, which is essential for their survival. • Sulbactam reduces bacterial resistance and enhances the activity of cefoperazone, thereby improving its efficacy against infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Zofactum-1Gm Inj
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.
  • Stay hydrated by taking fluids like water, juices and soups etc.
  • Eat fruits and vegetables which contain vitamins.
  • Take iron rich food like dry fruits, green leafy vegetables and sea food etc.
  • Reduce intake of milk, cheese, yogurt, soy, chocolate, ice cream, Grapes, Popcorn, canned salmon, pomegranate.
  • Regular exercise like walking, jogging is helpful.
  • Inform your doctor if you experience low hematocrit symptoms such as exhaustion, weakness, or pale complexion. Your doctor will diagnose the problem and recommend appropriate treatment.
  • Increase iron intake with iron-rich foods like red meat, poultry, fish, beans, and fortified cereals.
  • Consume vitamin C-rich foods such as citrus fruits, bell peppers, and tomatoes to improve iron absorption.
  • Avoid tea and coffee since they can interfere with iron absorption.
  • Don't smoke because it lowers the creation of red blood cells.
  • Consume beetroot juice, as it is rich in iron and supports red blood cell production.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

What if I have taken an overdose of Zofactum-1Gm Inj

The overdose of Zofactum-1Gm Inj is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Zofactum-1Gm Inj, please inform your doctor immediately.

Drug Warnings

  • Inform your doctor about all the medicines you are taking and about your health condition to rule out any unpleasant side effects.
  • Do not take Zofactum-1Gm Inj if you have an allergy to Zofactum-1Gm Inj, cephalosporins, or the penicillin class of antibiotics, as it may cause a skin rash, itching, and difficulty in breathing.
  • After taking Zofactum-1Gm Inj, if you have allergy-like symptoms, including rash, swelling of the face/lips/throat, difficulty in breathing, or tightness in the chest, immediately contact your doctor.
  • Do not take Zofactum-1Gm Inj if you have an allergy to Zofactum-1Gm Inj, cephalosporins, or the penicillin class of antibiotics, as it may cause a skin rash, itching, and difficulty in breathing.
  • People having liver disease or jaundice (yellowing of skin/eye) should not take Zofactum-1Gm Inj, as it can damage their liver severely.
  • You may experience diarrhoea, which can be managed by taking probiotics and maintaining adequate hydration.
  • Do not take antacids with Zofactum-1Gm Inj; maintain a 2-3-hour interval between them.
  • Avoid alcohol consumption while taking Zofactum-1Gm Inj to prevent unpleasant side effects.
  • Zofactum-1Gm Inj may cause dizziness; exercise caution when driving.

Drug-Drug Interactions

verifiedApollotooltip
CefoperazoneBCG vaccine
Critical
CefoperazoneRifampicin
Severe

Drug-Drug Interactions

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CefoperazoneBCG vaccine
Critical
How does the drug interact with Zofactum-1Gm Inj:
When BCG vaccine is used with Zofactum-1Gm Inj, its effectiveness may be reduced.

How to manage the interaction:
Taking Zofactum-1Gm Inj with BCG vaccine is not recommended, but can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor
CefoperazoneRifampicin
Severe
How does the drug interact with Zofactum-1Gm Inj:
Taking Zofactum-1Gm Inj and Rifampicin together may increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Zofactum-1Gm Inj and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Gut Health:

  • Take probiotic foods after completing the antibiotic course to restore healthy gut bacteria.
  • Include fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi.
  • Probiotics reduce the risk of diarrhoea after antibiotic use.

Diet:

  • Eat fibre-rich foods to support digestion and gut balance.
  • Include whole grains such as whole-grain bread and brown rice.
  • Include fruits and vegetables to support overall nutrition.

Hydration:

  • Drink plenty of water to prevent dehydration.
  • Fluids support the body during recovery from infection.

Habits:

  • Avoid alcohol as it can interfere with recovery.
  • Get enough rest to help the body fight infection.

Habit Forming

No

Therapeutic Class

[ANTI- BACTERIALS]

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Alcohol

Caution

Avoid the intake of alcohol while on treatment with Zofactum-1Gm Inj, as it may increase side effects.

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Pregnancy

Caution

Please consult your doctor if you are pregnant, your doctor will prescribe Zofactum-1Gm Inj only if the benefits outweigh the risks.

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Breast Feeding

Caution

Zofactum-1Gm Inj should be used with caution and only under a doctor's advice if you are a lactating mother. Please seek medical advice for more information.

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Driving

Caution

Zofactum-1Gm Inj may cause dizziness in some people, so it may affect your ability to drive.

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Liver

Caution

Dose adjustment may be needed. Please consult your doctor before taking Zofactum-1Gm Inj if you have liver impairment/liver disease.

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Kidney

Caution

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Zofactum-1Gm Inj.

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Children

Safe if prescribed

Zofactum-1Gm Inj should be given to children only when prescribed by a doctor. The doctor decides the right dose for a child based on his/her age and weight.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems.

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Geriatrics

Consult your doctor

Limited information available for use of Zofactum-1Gm Inj in elderly patients. Please consult your doctor.

FAQs

Zofactum-1Gm Inj is used to treat various bacterial infections such as respiratory tract (lungs) infection, urine infection, blood infection, meningitis (inflammation of the brain and spinal cord), gonorrhoea (sexually transmitted disease), skin, abdominal, bone, and joint infections.

No, do not stop receiving Zofactum-1Gm Inj before completing the full course of treatment. You may begin to feel better before the infection is fully resolved. But, it is important to take this medicine for the full duration advised by your doctor.

Inform your doctor if you do not feel better even after finishing the full course of treatment. You must also inform your physician if the symptoms worsen while using this medication.

Usually, Zofactum-1Gm Inj starts working soon after taking it. Though it may take a few days to kill all the dangerous bacteria and make you feel better.

Zofactum-1Gm Inj may cause Clostridium difficile-associated diarrhoea (CDAD). Treatment with antibiotics alters the normal flora, leading to overgrowth of Clostridium difficile; this causes diarrhoea. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, Zofactum-1Gm Inj is known to cause stomach upset. To avoid these side effects, please take Zofactum-1Gm Inj with a meal. Additionally, Zofactum-1Gm Inj should be administered at evenly spaced intervals to minimise adverse effects and optimise outcomes.

It's generally not recommended to consume alcohol while taking Zofactum-1Gm Inj, as it can increase gastrointestinal issues, enhance sedative effects, and interfere with the antibiotic's effectiveness. Consult your doctor for personalised advice.

Zofactum-1Gm Inj is a combination antibiotic medication used to treat various bacterial infections.

Zofactum-1Gm Inj typically begins to work within 1-2 hours after administration, but it may take 2-5 days to notice a significant improvement in symptoms. The full effect of the treatment may be observed after completion of the full course of antibiotics, typically 7-14 days.

Be patient, as it may take time for the infection to clear. If your symptoms don't improve or worsen over time, consult your doctor for further guidance.

Common side effects of Zofactum-1Gm Inj include nausea, vomiting, diarrhoea and rash. Most of these side effects are transient and resolve spontaneously. However, if they persist, it's essential to consult your doctor for proper evaluation and guidance.

Country of origin

INDIA

Manufacturer/Marketer address

“Elder House” Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai – 400053.
Other Info - ZOF0093

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