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compositionComposition:LINEZOLID-100MG
prescription
Prescription Medicine
info
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Zolidus Dry Syrup Orange is an antibiotic medication used to treat bacterial infections of the skin and soft tissues, lungs (pneumonia) and bloodstream infections. It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

LINEZOLID-100MG

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Zolidus Dry Syrup Orange

Zolidus Dry Syrup Orange is a prescription antibiotic used to treat serious bacterial infections, including certain severe types of pneumonia and complicated skin infections. It is typically reserved for infections that are suspected or proven to be caused by drug-resistant bacteria, helping to stop the spread of these difficult-to-treat organisms inside your body.

To clear the infection completely and prevent the bacteria from returning, you must take Zolidus Dry Syrup Orange consistently at the exact intervals prescribed by your physician. You can take this oral medication with or without food. However, while you are using this medicine, making specific temporary dietary adjustments is necessary to avoid potential complications, such as avoiding foods that are aged, fermented, or cured.

While taking Zolidus Dry Syrup Orange, you may experience mild and temporary side effects such as nausea, headaches, or diarrhoea. However, you should consult your doctor immediately if you experience severe watery diarrhoea, unusual bleeding or bruising, or sudden vision changes. Your healthcare provider will monitor your blood counts if you need to take this medication for an extended period.

Before starting your treatment, talk to your doctor if you have a history of high blood pressure, thyroid disorders, kidney disease, or bone marrow suppression. Do not take this medicine if you have taken a monoamine oxidase inhibitor (MAOI) antidepressant within the last 14 days, as this combination can lead to dangerous medical complications.

This medicine can interact with several common over-the-counter and prescription drugs, including cold remedies and specific antidepressants, which may lead to a life-threatening rise in blood pressure or a condition called serotonin syndrome. It is also important to consult your doctor before starting Zolidus Dry Syrup Orange if you are pregnant, planning to become pregnant, breastfeeding, or if you are managing health conditions as an older adult.

Uses of Zolidus Dry Syrup Orange

Zolidus Dry Syrup Orange may be prescribed for the following bacterial infections: 

  • Pneumonia: Helps clear severe lung infections, including hospital-acquired and community-acquired pneumonia, by stopping the growth of the responsible bacteria.
  • Skin and Skin Structure Infections: Effectively treats complicated skin infections, including those caused by drug-resistant bacteria like MRSA, helping the skin tissue heal.
  • Vancomycin-Resistant Enterococcus (VRE) Infections: Targets and eliminates hard-to-treat infections caused by enterococcal bacteria that have become resistant to other standard, strong antibiotics.

Key Benefits

Zolidus Dry Syrup Orange is an antibiotic used to treat serious bacterial infections, including infections caused by bacteria that may be resistant to other antibiotics. It helps eliminate infection and supports recovery.

  • Treats Resistant Bacterial Infections: Effective against certain bacteria that may not respond to commonly used antibiotics.
  • Helps Clear Serious Infections: Works to eliminate infection-causing bacteria and support the body's recovery process.
  • Reduces Infection Symptoms: Helps relieve symptoms such as fever, inflammation, pain, and discomfort associated with bacterial infections.
  • Supports Recovery Outside the Hospital: Its oral formulation may allow some patients to continue treatment at home after initial hospital care.
  • Prevents Infection Progression: Timely treatment helps reduce the risk of complications and the spread of infection.
Side effects of Zolidus Dry Syrup Orange

Directions for Use

Follow these instructions to use Zolidus Dry Syrup Orange correctly and safely: 

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet unless specifically advised by your doctor.
  • If you are taking the oral liquid suspension, shake the bottle thoroughly before each dose and use a marked medical measuring device to ensure you take the exact prescribed volume.
  • Take this medicine at evenly spaced intervals throughout the day to keep a constant level of the drug in your system.

Always follow your doctor's exact instructions and complete the entire prescribed course of treatment, even if you start to feel better after a few days.

How Zolidus Dry Syrup Orange Works

The active component in Zolidus Dry Syrup Orange, linezolid, belongs to a class of medications called oxazolidinones. It works by entering the bacterial cells and binding to a specific part of the bacteria's protein-making machinery. By blocking this crucial site, Zolidus Dry Syrup Orange prevents the bacteria from assembling the essential proteins they need to grow, multiply, and survive. Without the ability to produce these proteins, the bacteria cannot spread, allowing your immune system to naturally clear the remaining infection from your body.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Zolidus Dry Syrup Orange, as it may cause increased dizziness.

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Pregnancy

Consult your doctor

Zolidus Dry Syrup Orange belongs to pregnancy category C. If you are pregnant, please consult your doctor before using Zolidus Dry Syrup Orange. Your doctor will prescribe it only if the potential benefits justify the possible risks.

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Breast Feeding

Unsafe

Avoid taking Zolidus Dry Syrup Orange if you are breastfeeding, as it may pass into breast milk and cause harmful effects in the baby.

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Driving

Caution

Zolidus Dry Syrup Orange may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be necessary if you have liver impairment or disease. Please consult your doctor to discuss any concerns or to ensure safe and appropriate use.

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Kidney

Caution

Dose adjustment may be necessary if you have kidney impairment or disease. Please consult your doctor to discuss any concerns or to ensure safe and appropriate use.

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Children

Unsafe

Zolidus Dry Syrup Orange is not recommended for children below 18 years of age.

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Heart

Caution

Zolidus Dry Syrup Orange can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Zolidus Dry Syrup Orange to geriatric patients. Your doctor will prescribe Zolidus Dry Syrup Orange if the benefits outweigh the risks.

What if I have taken an overdose of Zolidus Dry Syrup Orange

If you suspect an overdose or experience severe symptoms like extreme dizziness, vomiting, or body tremors, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Limit Tyramine-Rich Foods: Avoid consuming large quantities of foods high in tyramine, such as aged cheeses, air-dried meats, red wine, tap beers, soy sauce, and sauerkraut, as they can interact with this medicine and cause a dangerous rise in blood pressure.
  • Stay Hydrated: Drink plenty of water throughout the day to support your body's recovery process and protect your kidneys while clearing the infection.
  • Support Gut Health: Consider taking a probiotic or eating yoghurt with active cultures a few hours after your antibiotic dose to help restore the balance of healthy bacteria in your gut.
  • Prioritise Rest: Allow your body ample rest so your immune system can focus its energy on fighting off the infection.
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How Soon It Starts Working

  • The time required for Zolidus Dry Syrup Orange to start to work: Zolidus Dry Syrup Orange ideally shows its action within 1 to 2 hours after administration.
  • The time for which the effects of Zolidus Dry Syrup Orange last: The effect of Zolidus Dry Syrup Orange lasts for 12 to 15 hours.

What if you forget to take Zolidus Dry Syrup Orange

If you miss a dose, take it as soon as you remember. However, if your next scheduled dose is only a few hours away, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Zolidus Dry Syrup Orange tablets at room temperature, between 20°C and 25°C (68°F to 77°F), in a dry place away from direct light and moisture. • Do not store this medication in your bathroom cabinet.

Drug Warnings

  • Check the Expiry Date: Always verify the expiry date before starting treatment.
  • Inspect the Liquid Suspension: If using the oral suspension, shake the bottle well and ensure the liquid appears uniform before use.
  • Monitor Blood Pressure: Check your blood pressure regularly during treatment, particularly if you have a history of high blood pressure.
  • Watch for Unusual Bleeding: Inform your doctor if you notice symptoms such as easy bruising, bleeding gums, or unusual bleeding.
  • Do Not Share Your Medicine: Never give Zolidus Dry Syrup Orange to another person, even if they have similar symptoms.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Zolidus Dry Syrup Orange:

  • MAO Inhibitors: Do not take Zolidus Dry Syrup Orange with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping them, as this may cause a dangerous increase in blood pressure.
  • Antidepressants: Medicines such as SSRIs, SNRIs, and tricyclic antidepressants may increase the risk of serotonin syndrome when taken with Zolidus Dry Syrup Orange.
  • Decongestants and Cold Medicines: Products containing pseudoephedrine may cause a significant rise in blood pressure when combined with Zolidus Dry Syrup Orange.
LinezolidImipramine
Critical
LinezolidCarbamazepine
Critical

Drug-Drug Interactions

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LinezolidImipramine
Critical
How does the drug interact with Zolidus Dry Syrup Orange:
Coadministration of Zolidus Dry Syrup Orange with Imipramine might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Zolidus Dry Syrup Orange and Imipramine together is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience confusion, hallucinations, seizures, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LinezolidCarbamazepine
Critical
How does the drug interact with Zolidus Dry Syrup Orange:
Using Carbamazepine with Zolidus Dry Syrup Orange can cause serotonin syndrome(a condition in which a chemical called serotonin builds up in your body).

How to manage the interaction:
Taking Carbamazepine and Zolidus Dry Syrup Orange together is not recommended, but it can be taken if prescribed by a doctor. However, if you experience symptoms such as confusion, hallucination, seizure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, stomach pain, nausea, vomiting, and diarrhea, consult the doctor. Do not discontinue any medications without consulting a doctor.
LinezolidVortioxetine
Critical
How does the drug interact with Zolidus Dry Syrup Orange:
Co-administration of Zolidus Dry Syrup Orange with Vortioxetine can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Zolidus Dry Syrup Orange with Vortioxetine can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea consult a doctor. Do not discontinue any medications without consulting a doctor.
LinezolidAtomoxetine
Critical
How does the drug interact with Zolidus Dry Syrup Orange:
Using Zolidus Dry Syrup Orange together with atomoxetine can cause high blood pressure.

How to manage the interaction:
Taking Zolidus Dry Syrup Orange with Atomoxetine is not recommended, consult a doctor before taking it. You should seek immediate medical attention if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting. Do not stop using any medications without talking to a doctor.
LinezolidMethylphenidate
Critical
How does the drug interact with Zolidus Dry Syrup Orange:
Taking Zolidus Dry Syrup Orange with Methylphenidate together may increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Zolidus Dry Syrup Orange with Methylphenidate is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden and severe headaches, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting, contact a doctor immediately. You may use methylphenidate only after you have been off Zolidus Dry Syrup Orange for at least 14 days. Do not discontinue any medications without consulting a doctor.
LinezolidTetrabenazine
Critical
How does the drug interact with Zolidus Dry Syrup Orange:
Coadministration of Zolidus Dry Syrup Orange and Tetrabenazine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Zolidus Dry Syrup Orange and Tetrabenazine together is not recommended as it can lead to an interaction, but it can be taken if a doctor advises. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LinezolidAmitriptyline
Critical
How does the drug interact with Zolidus Dry Syrup Orange:
Taking Zolidus Dry Syrup Orange with Amitriptyline can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Zolidus Dry Syrup Orange and Amitriptyline together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medications without consulting a doctor.
LinezolidModafinil
Critical
How does the drug interact with Zolidus Dry Syrup Orange:
Coadministration of Zolidus Dry Syrup Orange with Modafinil can increase the levels of Modafinil and increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Modafinil with Zolidus Dry Syrup Orange can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, excessive sweating, shortness of breath, chest pain or tightness, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LinezolidOxcarbazepine
Critical
How does the drug interact with Zolidus Dry Syrup Orange:
When Oxcarbazepine is taken with Zolidus Dry Syrup Orange, it can increase the risk of serotonin syndrome(a condition when your body has too much of a chemical called serotonin), further leading to side effects.

How to manage the interaction:
Taking Oxcarbazepine with Zolidus Dry Syrup Orange is not recommended, as it results in an interaction, it can be taken if advised by a doctor. However, if you experience symptoms such as confusion, hallucination (seeing or hearing things that do not exist), seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhoea, consult a doctor. Do not stop using any medications without a doctor’s advice.
LinezolidFentanyl
Critical
How does the drug interact with Zolidus Dry Syrup Orange:
Taking Zolidus Dry Syrup Orange with Fentanyl may increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although there is an interaction between Zolidus Dry Syrup Orange and Fentanyl, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, muscle pain, stomach cramps, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

verifiedApollotooltip

The following foods and beverages may interact with Zolidus Dry Syrup Orange: 

  • Tyramine-Rich Foods: Avoid or limit foods and beverages high in tyramine, such as aged cheeses, yeast extracts, soy sauce, and red wine, as they may trigger a sudden increase in blood pressure.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Zolidus Dry Syrup Orange is an antibiotic medication used to treat bacterial infections of the skin and lungs (pneumonia). It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections.
Zolidus Dry Syrup Orange contains Linezolid (an antibiotic), which works by stopping the bacteria from making proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.
Diarrhoea might be a side effect of Zolidus Dry Syrup Orange. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have prolonged diarrhoea with abdominal pain, stop taking Zolidus Dry Syrup Orange and consult your doctor. Do not take anti-diarrheal medicine on your own.
It is recommended to complete the course of Zolidus Dry Syrup Orange even if you feel better, as it is an antibiotic, and leaving it in between may lead to even more severe infection. To treat your condition effectively, continue taking Zolidus Dry Syrup Orange for as long as your doctor has prescribed it.
Zolidus Dry Syrup Orange may cause thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.
Do not take Zolidus Dry Syrup Orange on your own, as self-medication may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections.
Zolidus Dry Syrup Orange may affect certain laboratory test results, such as blood tests, blood sugar tests, and liver and kidney function tests. Inform the person doing the tests that you are taking Zolidus Dry Syrup Orange.
Zolidus Dry Syrup Orange may cause anaemia due to a decrease in the number of red blood cells. This could also cause unexplained bleeding or bruising. Consult your doctor if you experience unexplained bleeding or bruising.
Consult your doctor before taking Zolidus Dry Syrup Orange if you have hypertension (high blood pressure), as it may cause an increase in blood pressure.
You should avoid taking large quantities of food that contains high tyramine. Foods that are fermented, cured, aged or spoiled contain a high amount of tyramine, e.g. cheese, red wine, pickles, overripe fruits, etc. Consuming tyramine while taking Linezolid can result in an elevation of blood pressure, which may result in an emergency.
You should take it twice a day, every 12 hours, for example, at 8 a.m. and 8 p.m. You can take it before, with, or after food. Your doctor or clinician will determine the duration of the treatment course.
Zolidus Dry Syrup Orange is indicated for the treatment of gram-positive infections and is approved for treating skin and skin structure infections, bacterial pneumonia, and vancomycin-resistant enterococcal (VRE) infections, including those complicated by bacteremia.
It is usually taken with or without food or as directed by the doctor.
Common side effects of Zolidus Dry Syrup Orange may include thrush (fungal infection), headache, metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Please consult your doctor. Zolidus Dry Syrup Orange should be used during pregnancy or breastfeeding only if needed, and the benefit outweighs the risk to the fetus.
Take the missed dose as soon as you remember, unless it is almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.
It is highly recommended to avoid alcohol, especially red wine and tap beers, while taking Zolidus Dry Syrup Orange. These beverages contain high levels of tyramine, which can interact with the medication and cause a dangerous rise in blood pressure. Talk to your doctor or pharmacist for more information.
Zolidus Dry Syrup Orange begins working to stop the growth of bacteria within a few hours of your first dose. However, it may take a few days before you notice a significant improvement in your physical symptoms. Talk to your doctor if your symptoms do not improve after several days.
In rare cases, especially when taken for longer than 28 days, Zolidus Dry Syrup Orange can cause optic nerve damage, which may affect your vision. If you notice any blurred vision, changes in colour perception, or difficulty seeing, contact your doctor immediately.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.9919 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. MedlinePlus. A602004 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Linezolids Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. ScienceDirect ScienceDirect. [Accessed on 30 Mar. 2019]Check here
  5. Linezolid Linezolid. 2000. [Accessed on 30 Mar. 2019]Check here
  6. Linezolid 600 mg Tablet- Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 29 Dec 2025]Check here
  7. Linezolid 600 mg Tablet- Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2025 [Accessed on 29 Dec 2025]Check here

Country of origin

India
Other Info - ZO99449
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