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  3. Zolipax SR 0.5 Tablet 10's

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Zolipax SR 0.5 Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Zolipax SR 0.5 Tablet is used to treat severe anxiety over a short period and panic disorder with or without agoraphobia (an anxiety disorder that makes people very fearful of certain places and situations). It contains Alprazolam, which reduces anxiety/panic by decreasing abnormal and excessive excitement of nerve cells in the brain. It works by increasing the activity of GABA ( a chemical messenger in the brain that acts as a natural nerve-calming agent). Thereby, it relaxes muscles, reduces anxiety, and produces calm feeling, and helps to fall asleep. Some people may experience side effects such as depression, sleepiness and drowsiness, jerky, uncoordinated movements, inability to remember bits of information, slurred speech, dizziness, light-headedness, headaches, constipation, dry mouth, tiredness, and irritability.

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Composition :

ALPRAZOLAM-0.5MG

Manufacturer/Marketer :

Reliance Formulation Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zolipax SR 0.5 Tablet

Zolipax SR 0.5 Tablet is used to treat severe anxiety over a short period and panic disorder with or without agoraphobia (an anxiety disorder that makes people very fearful of certain places and situations). Anxiety is a mental health disorder associated with fear of worry and excessive nervousness. On the other hand, panic disorder is a type of anxiety disorder that causes sudden feelings of fear even when there is no real danger, with symptoms like a fast heartbeat.

Zolipax SR 0.5 Tablet reduces anxiety/panic by decreasing abnormal and excessive excitement of nerve cells in the brain. It works by increasing the activity of GABA ( a chemical messenger in the brain that acts as a natural nerve-calming agent). Thereby, Zolipax SR 0.5 Tablet relaxes muscles, reduces anxiety, produces a feeling of calm, and helps to fall asleep.

Take Zolipax SR 0.5 Tablet with or without food and swallow whole with a glass of water.  Your doctor will advise you on how often you take Zolipax SR 0.5 Tablet based on your medical condition. Some people may experience depression, sleepiness and drowsiness, jerky, uncoordinated movements, inability to remember bits of information, slurred speech, dizziness, light-headedness, headaches, constipation, dry mouth, tiredness, and irritability. Most of these side effects of Zolipax SR 0.5 Tablet do not require do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Zolipax SR 0.5 Tablet or any other medicines, please tell your doctor. Zolipax SR 0.5 Tablet is not recommended for children below 18 years of age. Do not take Zolipax SR 0.5 Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Inform your doctor if you have a drug addiction, muscle weakness, chronic pulmonary insufficiency, liver or kidney problem, or narrow-angle glaucoma (damage to optic nerve) before taking the Zolipax SR 0.5 Tablet . Do not take Zolipax SR 0.5 Tablet with opioids as it may cause breathing problems or other severe adverse effects.

Uses of Zolipax SR 0.5 Tablet

Zolipax SR 0.5 Tablet is used to treat anxiety disorder and panic disorder. The detailed uses of Zolipax SR 0.5 Tablet are as follows:<br/>• Anxiety Management: Zolipax SR 0.5 Tablet helps to alleviate anxiety symptoms, such as excessive worry and tension, providing relief for individuals with anxiety disorders.<br/>• Panic Disorder Treatment: Zolipax SR 0.5 Tablet helps treat panic disorders by reducing the frequency and intensity of panic attacks.<br/>• Sleep Aid: Zolipax SR 0.5 Tablet is sometimes used to help with sleep disturbances, particularly for anxiety-related insomnia, helping individuals fall asleep and stay asleep, especially in the initial stages of treatment.<br/>• Muscle Relaxation: Zolipax SR 0.5 Tablet can also be involved in relaxing muscles and relieving tension, providing relief for stress-related physical symptoms.<br/> • Sedation: Zolipax SR 0.5 Tablet can be used for sedation during medical procedures or before surgeries by helping to calm patients and reduce anxiety.<br/>

Directions for Use

• Zolipax SR 0.5 Tablet can be taken with or without food as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow Zolipax SR 0.5 Tablet as a whole with a glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Zolipax SR 0.5 Tablet is an anxiolytic drug (anxiety reducer) that is used to treat anxiety, and panic disorder over a short period. Zolipax SR 0.5 Tablet increases the activity of GABA (a chemical messenger in the brain that acts as a natural nerve-calming agent) and is involved in inducing sleep. Thereby, Zolipax SR 0.5 Tablet relaxes muscles, reduces anxiety, and induces sleep. Zolipax SR 0.5 Tablet is not to be used for mild anxiety associated with the stress of today's life situations.

How Zolipax SR 0.5 Tablet Works

It works by increasing the activity of GABA ( a chemical messenger in the brain that acts as a natural nerve-calming agent). Thereby, Zolipax SR 0.5 Tablet relaxes muscles, reduces anxiety, produces a feeling of calm, and helps to fall asleep.

Storage

Keep Zolipax SR 0.5 Tablet out of the sight and reach of children.
Side effects of Zolipax SR 0.5 Tablet
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Managing Medication-Triggered malaise (Feeling Unwell): A Step-by-Step Guide:
  • If you experience persistent or severe malaise (a general feeling of discomfort, illness, or unease) after taking medication, seek medical attention.
  • Inform your doctor about the medication you're taking and the symptoms you're experiencing.
  • Your treatment plan may be modified, which may include adjusting the dosage, substituting with an alternative medication, or discontinuing the medication. Additionally, certain lifestyle changes may be recommended to help manage symptoms.
  • To manage malaise symptoms, follow your doctor's advice, such as getting plenty of rest, staying hydrated, and practicing stress-reducing techniques.
  • Track your symptoms regularly and report any changes or concerns to your healthcare provider to ensure the malaise is managed effectively.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Get help from a health care professional.
  • Manage your feelings and things that trigger them.
  • Fuel your body with good food like fruits, veggies, and whole grains.
  • Find calm through activities like meditation or yoga.
  • Work on changing negative patterns and thoughts.
  • Focus on being healthy overall, not just how you look.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. Use extra pillows to elevate your position and prop your chest up while sleeping.

What if I have taken an overdose of Zolipax SR 0.5 Tablet

Do not take more than the prescribed dose of Zolipax SR 0.5 Tablet as it may cause overdose. The symptoms of overdose include problems with coordination, drowsiness, confusion and loss of consciousness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Zolipax SR 0.5 Tablet if you are known to be allergic to Zolipax SR 0.5 Tablet . Zolipax SR 0.5 Tablet is not recommended for below 18 years of age. Do not take Zolipax SR 0.5 Tablet if you are pregnant or breastfeeding as it may cause adverse effects in the baby. Zolipax SR 0.5 Tablet should be used with caution in elderly patients as there is an increased risk of adverse reactions such as drowsiness, dizziness, and muscle weakness. Inform your doctor if you have myasthenia gravis (muscle weakness), drug addiction, chronic pulmonary insufficiency, narrow-angle glaucoma, kidney/liver problem before taking Zolipax SR 0.5 Tablet . Do not take Zolipax SR 0.5 Tablet with opioids as it may cause breathing problems, drowsiness, and coma.

Drug-Drug Interactions

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AlprazolamItraconazole
Critical
AlprazolamClarithromycin
Critical

Drug-Drug Interactions

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AlprazolamItraconazole
Critical
How does the drug interact with Zolipax SR 0.5 Tablet:
Zolipax SR 0.5 Tablet's blood levels may be significantly raised when combined with itraconazole.

How to manage the interaction:
Although combining Zolipax SR 0.5 Tablet and Itraconazole may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
AlprazolamClarithromycin
Critical
How does the drug interact with Zolipax SR 0.5 Tablet:
The combination of Zolipax SR 0.5 Tablet and clarithromycin may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zolipax SR 0.5 Tablet and clarithromycin, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.
AlprazolamKetoconazole
Critical
How does the drug interact with Zolipax SR 0.5 Tablet:
Co-administration of Zolipax SR 0.5 Tablet with Ketoconazole may considerably increase the blood levels of Zolipax SR 0.5 Tablet, which may result in side effects.

How to manage the interaction:
Although there is an interaction between Zolipax SR 0.5 Tablet and Ketoconazole, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamDelavirdine
Critical
How does the drug interact with Zolipax SR 0.5 Tablet:
The combination of Zolipax SR 0.5 Tablet and Delavirdine may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zolipax SR 0.5 Tablet and Delavirdine, it can be used if prescribed by a doctor. Consult a doctor if you have sleepiness, dizziness, confusion, or weak or rapid breathing over a long duration of time. Do not discontinue any medications without consulting a doctor.
AlprazolamCeritinib
Critical
How does the drug interact with Zolipax SR 0.5 Tablet:
Co-administration of Zolipax SR 0.5 Tablet with Ceritinib may considerably increase the blood levels and effects of Zolipax SR 0.5 Tablet.

How to manage the interaction:
Although there is a interaction between Zolipax SR 0.5 Tablet and Ceritinib, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamCobicistat
Critical
How does the drug interact with Zolipax SR 0.5 Tablet:
Co-administration of Zolipax SR 0.5 Tablet with Cobicistat may considerably increase the blood levels and effects of Zolipax SR 0.5 Tablet.

How to manage the interaction:
Despite the fact that there is an interaction between Zolipax SR 0.5 Tablet and Cobicistat, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamIndinavir
Critical
How does the drug interact with Zolipax SR 0.5 Tablet:
The combination of Zolipax SR 0.5 Tablet and Indinavir may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zolipax SR 0.5 Tablet and Indinavir, it can be used if prescribed by a doctor. Consult a doctor if you have drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamSodium oxybate
Critical
How does the drug interact with Zolipax SR 0.5 Tablet:
Co-administration of Zolipax SR 0.5 Tablet with Sodium Oxybate may increase Sodium Oxybate's adverse effects (respiratory depression, low blood pressure, fainting).

How to manage the interaction:
Although the combination of Zolipax SR 0.5 Tablet and sodium oxybate may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you suffer any of the following symptoms: breathing difficulties, low blood pressure, being severely drowsy, or fainting. Avoid driving or operating hazardous machinery or performing other hazardous activities for at least 6 hours after taking a dose. Do not discontinue any medications without consulting a doctor.
AlprazolamEsketamine
Severe
How does the drug interact with Zolipax SR 0.5 Tablet:
Using Esketamine together with Zolipax SR 0.5 Tablet may increase side effects (drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination).

How to manage the interaction:
Although the combination of Zolipax SR 0.5 Tablet and Esketamine may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, drowsiness, difficulty concentrating, or impairment in judgment, reaction speed, or control of movements. Do not discontinue any medications without consulting a doctor.
AlprazolamPentazocine
Severe
How does the drug interact with Zolipax SR 0.5 Tablet:
Taking Zolipax SR 0.5 Tablet with Pentazocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is an interaction between Zolipax SR 0.5 Tablet and Pentazocine, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, sleepiness, or difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a regular sleep pattern. Do not take a nap during day time.
  • Avoid watching Tv, using mobiles or laptops just before bedtime.
  • Maintain a diet rich in fruits, vegetables, and whole grains. Avoid fried foods, high-fat dairy products, pastries, and processed foods as they may worsen anxiety.
  • Do regular exercise and maintain healthy body weight.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

Yes

Therapeutic Class

ANXIOLYTICS

Zolipax SR 0.5 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol with Zolipax SR 0.5 Tablet as it may increase the risk of drowsiness and other adverse effects.

bannner image

Pregnancy

Unsafe

Zolipax SR 0.5 Tablet is a category D pregnancy drug. It is not recommended for use during pregnancy, especially in the second and third trimesters as it may cause harm to the unborn baby.

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while taking Zolipax SR 0.5 Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

bannner image

Driving

Unsafe

Zolipax SR 0.5 Tablet may cause dizziness, double vision, or drowsiness in some people. It is an offence to drive if Zolipax SR 0.5 Tablet affects you. Therefore, avoid driving if you feel drowsy, dizzy, or experience any vision problems after taking Zolipax SR 0.5 Tablet .

bannner image

Liver

Caution

Take Zolipax SR 0.5 Tablet with caution, especially if you have or had a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Kidney

Caution

Take Zolipax SR 0.5 Tablet with caution, especially if you have or had a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

bannner image

Children

Caution

Zolipax SR 0.5 Tablet should not be used by children, as the efficacy and safety have not established.

Have a query?

FAQs

Zolipax SR 0.5 Tablet is used to treat severe anxiety over a short period and panic disorder with or without agoraphobia (an anxiety disorder that makes people very fearful of certain places and situations).

Zolipax SR 0.5 Tablet reduces anxiety/panic by decreasing abnormal and excessive excitement of nerve cells in the brain. It works by increasing the activity of GABA ( a chemical messenger in the brain that acts as a natural nerve-calming agent). Thereby, Zolipax SR 0.5 Tablet relaxes muscles, reduces anxiety, produces a feeling of calm, and helps to fall asleep.

No, Zolipax SR 0.5 Tablet is not indicated for the treatment of heart palpitations. However, it may help in reducing heart palpitation associated with anxiety. Zolipax SR 0.5 Tablet should always be taken only when advised by your doctor.

Yes, Zolipax SR 0.5 Tablet may cause mental or physical dependence if used for a prolonged time. Therefore, take Zolipax SR 0.5 Tablet only in dose and duration as advised by your doctor.

No, Zolipax SR 0.5 Tablet is not used for the treatment of any pain. It is used for the treatment of anxiety.

No, you are not recommended to take Zolipax SR 0.5 Tablet with codeine as co-administration of these medicines may cause breathing problems, drowsiness, and coma. However, before using Zolipax SR 0.5 Tablet with codeine and any other opioids, you are advised to contact your doctor so that the dosage may be adjusted accordingly to use safely.

Zolipax SR 0.5 Tablet is generally safe when used as prescribed by a doctor. However, it has a high potential for habit forming and should be used with caution. Do not exceed the recommended dose.

No, Zolipax SR 0.5 Tablet is not an opioid. It belongs to the class of medications called benzodiazepines.

No, Zolipax SR 0.5 Tablet is not an antidepressant. It is used to treat anxiety.

No, Zolipax SR 0.5 Tablet is not a narcotic substance. It belongs to the class of medications called benzodiazepines.

No, Zolipax SR 0.5 Tablet is not used to manage hangover. Taking Zolipax SR 0.5 Tablet with alcohol can cause excessive sedation and depress your brain.

Yes, Zolipax SR 0.5 Tablet is used to treat severe anxiety over a short period and panic disorder with or without agoraphobia (an anxiety disorder that makes people very fearful of certain places and situations). It is not recommended for mild anxiety caused by stress of day to day life situations.

Zolipax SR 0.5 Tablet overdose may cause low blood pressure. Thus, do not exceed recommended doses. However, if you experience severe low blood pressure while taking Zolipax SR 0.5 Tablet , consult your doctor.

Yes, Zolipax SR 0.5 Tablet can cause sleepiness as a side effect. This usually reduces over time and doesn’t require medical attention. If it persists or worsens, please consult your doctor.

Yes, Zolipax SR 0.5 Tablet can cause changes in weight as a side effect. This can vary from person to person. If you notice any significant changes in your weight while taking Zolipax SR 0.5 Tablet , it's important to discuss it with your doctor.

No, you should not take Zolipax SR 0.5 Tablet with hydrocodone. Combining these medications can lead to profound sedation, and respiratory depression. It's important to consult your doctor before taking Zolipax SR 0.5 Tablet with hydrocodone or other medications to avoid any potential risks.

You are recommended to consult your doctor before taking Zolipax SR 0.5 Tablet with paracetamol or other medications to avoid any potential interactions.

No, Zolipax SR 0.5 Tablet is generally not intended for long-term use due to its potential for habit formation and dependence. It's usually prescribed for short-term management of anxiety and panic disorders. Prolonged use can lead to tolerance. It's important to follow your doctor's guidance and have regular check-ups to monitor your condition and adjust the treatment as needed.

The common side effects of Zolipax SR 0.5 Tablet are drowsiness, dizziness, headache, dry mouth, blurred vision, abdominal pain, constipation, fatigue (overtiredness) and irritability. If these side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Dhirubhai Ambani Life Sciences Centre, R-282, Ttc Area Of Midc, Thane-Belapur Road, Rabale, Navi Mumbai 400 701.
Other Info - ZOL0084

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 18, 2025 | 6:36 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/product/1657/smpc
  2. https://www.drugs.com/drug-interactions/alprazolam-index.html
  3. https://medlineplus.gov/druginfo/meds/a684001.html

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