Zone-F Cream is a dermatological combination medicine used to reduce swelling/inflammation, itching and redness caused due to certain fungal skin infections. Fungal infection is a skin disease in which a fungus attacks the tissue and cause infection. Fungal infections may be contagious (spread from one person to another).

Zone-F Cream is a combination of two drugs, namely: Fluocinolone acetonide (corticosteroid) and Miconazole (antifungal). Fluocinolone acetonide belongs to the class of corticosteroids that works by preventing the release of certain chemical messengers in the body that cause redness, itching and swelling. On the other hand, Miconazole belongs to the class of antifungals that works by causing holes in the fungal cell membranes thereby killing the fungi.

Zone-F Cream is only for external use. Use Zone-F Cream as prescribed. Your doctor will recommend how often you use Zone-F Cream based on your medical condition. Avoid contact of Zone-F Cream with nose, ears, mouth or eyes. In case Zone-F Cream comes in contact with these areas accidentally, rinse with water thoroughly. Some people may experience dry skin, skin peeling, increased hair growth, pimples, patches of pale skin, itching, irritation or burning sensation at the site of application. Most of these side effects of Zone-F Cream do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Zone-F Cream or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Zone-F Cream. Do not use Zone-F Cream in more than prescribed doses, or for a prolonged time as it may cause adverse effects such as skin thinning, visible small veins or stretch marks.  Avoid using Zone-F Cream for more than 5 days in children and on the face. Do not apply Zone-F Cream on open wounds, cuts, scrapes or damaged skin. Do not swallow Zone-F Cream. In case of accidental swallowing, contact nearby poison control centre or consult a doctor immediately. If you have rosacea (redness and often red, small, pus-filled bumps on the face), acne, perioral dermatitis (red, bumpy rash around the mouth), any skin infection, psoriasis, diabetes, liver or adrenal gland problems, inform your doctor before taking Zone-F Cream.

Zone-F Cream is a combination of two drugs, namely, Fluocinolone acetonide and Miconazole. Zone-F Cream is used to reduce swelling, itching and redness caused due to fungal skin infections. Fluocinolone acetonide is a corticosteroid that acts inside skin cells and inhibits the release of certain chemical messengers in the body that cause redness, itching and swelling. When the skin reacts to any allergens, such chemicals are released normally. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Miconazole is an antifungal that causes holes in the fungal cell membranes and kills fungi. Thereby, clears fungal infection and provides relief from cracking, burning, scaling and itching of the skin caused due to infections.

• Dry skin
• Skin peeling
• Increased hair growth
• Pimples
• Patches of pale skin
• Itching, irritation or burning sensation at the site of application

If you are known to be allergic to Zone-F Cream or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Zone-F Cream. Do not use Zone-F Cream in more than prescribed doses, or for a prolonged time as it may cause adverse effects such as skin thinning, visible small veins or stretch marks.  Avoid using Zone-F Cream for more than 5 days in children and on the face. Do not apply Zone-F Cream on open wounds, cuts, scrapes or damaged skin. Do not swallow Zone-F Cream. In case of accidental swallowing, contact nearby poison control center or consult a doctor immediately. If you have rosacea (redness and often red, small, pus-filled bumps on the face), acne, perioral dermatitis (red, bumpy rash around the mouth), any skin infection, psoriasis, diabetes, liver or adrenal gland problems, inform your doctor before taking Zone-F Cream.

Drug-Drug Interaction: Zone-F Cream may interact with anticoagulants (warfarin, dicumarol, anisindione).

Drug-Food Interaction: Zone-F Cream may interact with grapefruit and grapefruit juice. Thus, avoid intake of grapefruit juice while using Zone-F Cream as it may lead to adverse effects. Also, inform your doctor if you are taking any herbal supplements, vitamins or OTC medicines.

Drug-Disease Interaction: If you have rosacea (redness and often red, small, pus-filled bumps on the face), acne, perioral dermatitis (red, bumpy rash around the mouth), any skin infection, psoriasis, diabetes, liver or adrenal gland problems, inform your doctor before taking Zone-F Cream.

• WARFARIN
• DICUMAROL
• ANISINDIONE

• Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
• In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
• Do not scratch the affected area of skin as it can spread the infection to other body parts.
• Avoid sharing towels, combs, bedsheets, shoes or socks with others.
• Wash your bed sheets and towels regularly.

Avoid contact of Zone-F Cream with nose, mouth or eyes. In case Zone-F Cream comes in contact with these areas accidentally, rinse with water thoroughly.

Fungal infection is a skin disease in which a fungus attacks the tissue and cause infection. Fungal infections may be contagious (spread from one person to another). The symptoms of a fungal infection include scaly skin, blisters, itching, swelling, irritation and redness. Antifungal medicines are usually used to treat fungal infections. Avoid sharing things to prevent the spread of infection. Keep the affected area clean and dry, wear flip-flops or sandals in locker rooms and avoid tight-fitting shoes or clothes to prevent fungal infections.