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  3. Zonimid-25 Capsule 10's

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Zonimid-25 Capsule 10's, Pack of 10 CapsuleS
Zonimid-25 Capsule 10's, Pack of 10 CapsuleS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Zonimid-25 Capsule is used to treat epilepsy (seizures/fits). It contains Zonisamide, which reduces the abnormal and excessive activity of nerve impulses in the brain that cause fits or seizures. In some cases, you may experience certain common side effects such as dizziness, irritability, loss of appetite, nausea, headache, or uncontrolled movements. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

ZONISAMIDE-25MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Zonimid-25 Capsule

Zonimid-25 Capsule is used to treat epilepsy (seizures/fits). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

Zonimid-25 Capsule contains 'Zonisamide’ that reduces the abnormal and excessive activity of nerve impulses in the brain that cause fits or seizures. This helps in controlling seizures.

In some cases, you may experience certain common side effects such as dizziness, irritability, loss of appetite, constipation, nausea, headache, and uncontrolled movements. Talk to your doctor if you experience these side effects persistently.

Inform your doctor about your health conditions and medicines to prevent side effects. Do not take Zonimid-25 Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Zonimid-25 Capsule can cause permanent vision loss. Inform your doctor immediately if you have any eye pain, redness, or any changes in your vision.

Uses of Zonimid-25 Capsule

Zonimid-25 Capsule is used in the treatment of epilepsy/seizures. The detailed use of Zonimid-25 Capsule is as follows:

  • Seizure Management: Zonimid-25 Capsule is used as adjunctive therapy to control partial seizures in epilepsy patients by stabilising abnormal electrical activity in the brain.

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Directions for Use

  • Zonimid-25 Capsule can be taken with or without food as advised by your doctor.
  • It is usually taken once or twice a day or as directed by the doctor.
  • Swallow Zonimid-25 Capsule as a whole with a glass of water.
  • Do not chew, crush, or break it.

Medicinal Benefits

  • Zonimid-25 Capsule belongs to a group of medicines called anti-convulsants or anti-epileptics used to treat epilepsy/seizures/fits.
  • It works by blocking the sodium and calcium currents in the brain and suppressing the abnormal and excessive activity of nerve impulses in the brain that cause fits and pain. This helps in controlling seizures.
  • Zonimid-25 Capsule is used alone or in combination to treat and prevent partial seizures and generalised seizures in adults.
  • It may be used as solo therapy or in combination to treat and prevent seizures in children above 6 years of age.
  • Zonimid-25 Capsule is not associated with any psychological or physical dependence, and there is no potential for abuse.

How Zonimid-25 Capsule Works

Zonimid-25 Capsule contains Zonisamide, which reduces the abnormal and excessive activity of nerve impulses in the brain that cause fits or seizures. This helps in controlling seizures.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Zonimid-25 Capsule
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Participating in activities you enjoy, or exercising may also help manage agitation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
  • Manage stress by practising deep breathing, yoga or meditation.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Exercise regularly. Try physical activities like walking, running, or dancing.
  • Limit stimulants like tea, coffee and alcohol.
  • Identify triggers and try managing them.
  • Take a break by scheduling time for yourself.
  • Try creative activities like writing, dancing or painting as it helps release tension.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Regular eye exams can detect conditions causing Involuntary Eye Movement.
  • Alcohol and drugs should be avoided as they can increase the symptoms of nystagmus.
  • Wearing corrective lenses for refractive errors can reduce eye strain and symptoms.
  • Stress management and getting proper sleep can help to reduce symptoms.

What if I have taken an overdose of Zonimid-25 Capsule

Do not take more than the prescribed dose of Zonimid-25 Capsule as it may cause serious side effects. The symptoms of overdose include slow heart rate, fainting, feeling lightheaded, and shallow or slow breathing. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Zonimid-25 Capsule if you are allergic to it or any of its contents.
  • Avoid intake of Zonimid-25 Capsule if you are pregnant or planning for pregnancy unless prescribed by the doctor.
  • Breastfeeding mothers should consult the doctor before using Zonimid-25 Capsule .
  • Zonimid-25 Capsule should not be given to children unless prescribed.
  • Inform your doctor before taking Zonimid-25 Capsule if you have or have had kidney and liver problems, glaucoma, high levels of ammonia, osteoporosis, depression, heart problems, or if you have low levels of bicarbonate in your blood, or if you have previously suffered from kidney stones.
  • Do not stop taking Zonimid-25 Capsule without consulting your doctor to avoid worsening of seizure episodes.
  • Zonimid-25 Capsule causes drowsiness and dizziness, so drive only if you are alert.
  • Avoid consuming alcohol along with Zonimid-25 Capsule as it could lead to increased dizziness and sleepiness.
  • Consult your doctor immediately if you experience mood swings or suicidal tendencies.
  • Zonimid-25 Capsule can cause permanent vision loss. If you experience any eye pain, redness, or vision changes, inform your doctor immediately.

Drug-Drug Interactions

verifiedApollotooltip
ZonisamideLurasidone
Severe
ZonisamideRisperidone
Severe

Drug-Drug Interactions

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ZonisamideLurasidone
Severe
How does the drug interact with Zonimid-25 Capsule:
When lurasidone and Zonimid-25 Capsule are taken together, they can induce a rise in body temperature and a decrease in sweating. Children are especially susceptible.

How to manage the interaction:
Even though lurasidone and Zonimid-25 Capsule interact, they can be used if prescribed by a doctor. Heat stroke and hospitalization are possible in some persons, particularly in hot weather and during intense physical activity. Consult a doctor if you suffer any symptoms such as sleepiness, dizziness, or lightheadedness. Do not discontinue any medications without consulting a doctor.
ZonisamideRisperidone
Severe
How does the drug interact with Zonimid-25 Capsule:
Coadministration of Risperidone with Zonimid-25 Capsule can increase the risk of Zonimid-25 Capsule side effects.

How to manage the interaction:
Taking Risperidone with Zonimid-25 Capsule together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ZonisamideTrospium
Severe
How does the drug interact with Zonimid-25 Capsule:
Coadministration of Trospium with Zonimid-25 Capsule can increase the risk or severity of Zonimid-25 Capsule side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Trospium with Zonimid-25 Capsule together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
ZonisamideNortriptyline
Severe
How does the drug interact with Zonimid-25 Capsule:
Coadministration of Nortriptyline with Zonimid-25 Capsule can increase the risk or severity of side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Nortriptyline with Zonimid-25 Capsule together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience decreased sweating, fever, drowsiness, dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, severe or prolonged diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ZonisamideMetformin
Severe
How does the drug interact with Zonimid-25 Capsule:
The combined use of Metformin with Zonimid-25 Capsule may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Co-administration Metformin with Zonimid-25 Capsule can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience any symptoms such as weakness, muscle pain, respiratory distress, consult a doctor immediately. Do not stop using any medication without a doctor's advice.
ZonisamideQuetiapine
Severe
How does the drug interact with Zonimid-25 Capsule:
Coadministration of Quetiapine with Zonimid-25 Capsule can increase the risk or severity of Zonimid-25 Capsule side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Quetiapine with Zonimid-25 Capsule together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
ZonisamideZiprasidone
Severe
How does the drug interact with Zonimid-25 Capsule:
Co-administration of Ziprasidone with Zonimid-25 Capsule can increase the risk or severity of Zonimid-25 Capsule side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Ziprasidone with Zonimid-25 Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ZonisamidePropantheline
Severe
How does the drug interact with Zonimid-25 Capsule:
Coadministration of Propantheline with Zonimid-25 Capsule can increase the risk or severity of Zonimid-25 Capsule side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Propantheline with Zonimid-25 Capsule together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
ZonisamideCyclobenzaprine
Severe
How does the drug interact with Zonimid-25 Capsule:
Coadministration of Zonimid-25 Capsule with Cyclobenzaprine can cause increased body temperature and decrease sweating.

How to manage the interaction:
Taking Cyclobenzaprine with Zonimid-25 Capsule together is generally avoided as it can result in an interaction, it can be taken only if your doctor has advised it. However, if you experience changes in fever, shortness of breath, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
ZonisamideHaloperidol
Severe
How does the drug interact with Zonimid-25 Capsule:
Coadministration of Haloperidol with Zonimid-25 Capsule can increase the risk or severity of developing Zonimid-25 Capsule side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Haloperidol with Zonimid-25 Capsule together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Zonimid-25 Capsule as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking Zonimid-25 Capsule if you are pregnant unless prescribed by a doctor to lead to serious birth defects/congenital disabilities. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Zonimid-25 Capsule should not be taken by breastfeeding mothers as it passes into breast milk and could lead to side-effects for breastfed babies.

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Driving

Unsafe

Zonimid-25 Capsule causes drowsiness, sleepiness, and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Children

Safe if prescribed

Zonimid-25 Capsule can be given to children above 6 years if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

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Heart

Consult your doctor

Please inform your doctor if you have any pre-existing heart problems

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Geriatrics

Consult your doctor

Limited information available for use of Zonimid-25 Capsule in elderly patients. Please consult your doctor.

FAQs

Zonimid-25 Capsule belongs to a group of medicines called anti-convulsants or anti-epileptics used to treat epilepsy (seizures/fits).

Zonimid-25 Capsule consists of zonisamide, which decreases the brain's excessive and abnormal nerve activity by blocking sodium and calcium currents in your brain and body. This reduces abnormal electrical activity between your nerve cells.

Consult your doctor before taking Zonimid-25 Capsule if you are pregnant or planning a pregnancy. Your doctor will prescribe Zonimid-25 Capsule only if the benefits outweigh the risks. If you are planning for pregnancy, use contraception while taking Zonimid-25 Capsule .

Zonimid-25 Capsule should be used with caution during hot weather, as it may increase the chance of having a heat stroke. Inform your doctor if you have heat intolerance or fever. To avoid this condition, it is advisable to drink a lot of cold fluid and water and move to a cooler place, especially in summer.

No, Zonimid-25 Capsule is not a habit-forming drug. However, it can cause side effects, especially when you stop taking it suddenly.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - ZON0042

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Dec 3, 2025 | 7:35 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.72.pdf
  2. https://www.drugs.com/mtm/zonisamide.html
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020789s034lbl.pdf

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