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compositionComposition:ACITRETIN-10MG
prescription
Prescription Medicine
info
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Zoratame 10mg Capsule is used to treat psoriasis. It contains Acitretin, which slows down the progression of the disease. It slows the growth of skin cells and gradually clears the affected skin. It helps reduce the redness, scaling, and thickness of psoriasis rashes. It may cause side effects such as dry lips, skin peeling, skin scaling and thinning, skin reddening, and a burning or itching sensation on the skin.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ACITRETIN-10MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Zoratame 10mg Capsule

Zoratame 10mg Capsule is an oral prescription medicine used to treat severe skin conditions, including severe plaque, pustular, and erythrodermic psoriasis. It is prescribed for cases that do not respond well to other treatments. The main purpose of this medicine is to control the rapid growth and accumulation of skin cells.

For the best results, you must take Zoratame 10mg Capsule consistently once daily, exactly as directed by your healthcare provider. Always take this medicine with a main meal or with a glass of milk, as fat in your food helps your body absorb the medication much better. Additionally, incorporating a gentle moisturising routine and staying well-hydrated can significantly help manage dry skin during treatment.

While using this medication, you may experience common side effects like dry lips, peeling skin on your palms and soles, and dry eyes. If you develop serious side effects, such as a severe, persistent headache, yellowing of your skin or eyes, or sudden mood changes, you must consult your doctor immediately.

Before starting your treatment, talk to your doctor if you have a history of liver problems, high cholesterol, kidney disease, or diabetes. Do not take this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Because of the extreme risk of severe birth defects, female patients must strictly avoid pregnancy during treatment and for three years after stopping this medicine.

This medicine can interact with several substances; for example, you must completely avoid alcohol because it converts the medication into a substance that stays in your body for years, increasing the risk of birth defects. Do not take vitamin A supplements, as they can lead to dangerous toxic build-up in your body. Always consult your doctor or pharmacist if you are an older adult or have other underlying health conditions before starting this treatment.

Uses of Zoratame 10mg Capsule

Zoratame 10mg Capsule is used to treat severe skin conditions, including severe plaque, pustular, and erythrodermic psoriasis. The detailed uses of Zoratame 10mg Capsule are as follows:

  • Severe Psoriasis: Zoratame 10mg Capsule helps control severe, widespread plaque psoriasis, pustular psoriasis, and erythrodermic psoriasis by slowing down the rapid multiplication of skin cells.
  • Severe Keratinisation Disorders: This medicine is used to treat severe skin scaling conditions, such as ichthyosis and Darier’s disease, by helping normal skin cells form correctly.

Key Benefits

Zoratame 10mg Capsule provides profound relief for individuals struggling with severe, stubborn skin conditions that have not responded to other treatments. By targeting the root cause of rapid skin cell production, it delivers several key benefits:

  • Reduces Skin Scaling and Thickness: It noticeably thins and softens thick, scaly plaques, allowing your skin to regain a smoother, more comfortable texture.
  • Eases Pain and Itching: By reducing inflammation and clearing lesions, Zoratame 10mg Capsule helps relieve the intense itching, cracking, and physical discomfort associated with severe psoriasis.
  • Clears Widespread Skin Lesions: Over time, this treatment helps clear large areas of affected skin, helping you feel more confident and comfortable in your daily life.
Side effects of Zoratame 10mg Capsule
  • Know your allergens that cause dermatitis and avoid them.
  • Use fragrance-free detergents and soaps.
  • Apply moisturizer after taking bath to retain moisture in the skin.
  • Apply cool, moist compresses to the rash.
  • Talk to your doctor about creams and ointments to manage your dermatitis.
Managing Medication-Related Skin Allergies: A Step-by-Step Guide
  • If you experience signs of skin allergies such as redness, itching, or irritation after taking medication, contact your doctor right away.
  • To alleviate skin allergy symptoms, your doctor may change your medication regimen or offer tailored medication management advice.
  • Your doctor may recommend or prescribe drugs to relieve discomfort.
  • Cool compresses or calamine lotion can help relieve redness and itching on the afflicted skin area.
  • Staying hydrated by consuming plenty of water can help relieve discomfort.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the steps to manage angioedema (Swelling Under The Skin) as a side effect of medication:
  • If you experience angioedema, inform your doctor immediately. Treatment can help keep the swelling under control.
  • Seek medical attention if symptoms are severe, such as difficulty breathing or swallowing.
  • Follow your doctor's instructions to manage symptoms, which may include stopping or adjusting the medication that triggered angioedema.
  • Your doctor may also recommend antihistamines, steroids, or other treatments to reduce swelling and inflammation.
  • Make dietary and lifestyle changes as recommended, such as avoiding trigger foods or reducing stress.
  • Monitor your condition closely and track your symptoms to report them to your doctor.
  • Consult your doctor again if symptoms worsen or do not improve or if you experience any new or concerning symptoms.
  • Avoid trigger foods that can cause allergic reactions, such as nuts, shellfish, or dairy products.
  • Keep a food diary to track potential food allergens.
  • Include omega-3 rich foods like salmon and walnuts to reduce inflammation.
  • Wear loose, comfortable clothing made from soft fabrics like cotton.
  • Apply cool compresses or take cool baths to reduce itching.
  • Use gentle soaps and avoid harsh skin products.
  • Reduce stress through relaxation techniques like meditation or deep breathing.
  • Try to practice deep breathing exercises or repeat calming words or phrases.
  • Seek for medical help if aggression occurs frequently, as it can worsen gradually if not attended.
  • You can also try listening to music or relaxing or writing a journal to express the feeling that aggravates to find a solution.
  • Suicidal thoughts need immediate medical attention else they can be uncontrollable.
  • Try to be in a comfortable space where there is someone to share your thoughts and discuss your problem.
  • Regularly do strengthening exercises to divert your thought process.
  • Prevent smoking and drinking alcohol, as they can affect your mind and increase suicidal thoughts.
  • Keep yourself engaged in any activity that prevents suicidal thoughts.
  • Practice yoga and meditation to improve your mental and overall health.
  • Eat fiber-rich foods like broccoli, cauliflower, leafy greens, and Brussels sprouts.
  • Limit sugar and refined carbs like avoid sugary drinks, white bread, and processed foods.
  • Choose lean protein sources like chicken, fish, and tofu.
  • Choose low-sugar fruits like berries, citrus fruits, and apples in moderation.
  • Maintain good hygiene and keep affected areas clean and dry.
  • Wear breathable clothing to reduce moisture.
  • Consider natural antifungal agents like coconut oil, tea tree oil, and garlic (consult a healthcare professional before use).

Directions for Use

  • Zoratame 10mg Capsule can be taken preferably with meals or a glass of milk as advised by a doctor.
  • It is advised to take Zoratame 10mg Capsule once daily, or as directed by your doctor, at the same time each day for best results.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Zoratame 10mg Capsule Works

Zoratame 10mg Capsule contains acitretin, which belongs to a group of medicines called systemic retinoids, which are closely related to vitamin A. In people with severe psoriasis, the skin cells grow and multiply much faster than normal, leading to a buildup of thick, scaly patches. Zoratame 10mg Capsule works by directly targeting the lifecycle of these skin cells. Once absorbed, it signals your body to slow down the hyperactive growth of skin cells. It encourages the cells to grow and mature normally instead of piling up on the surface of your skin. Additionally, it helps decrease the localised inflammation that causes redness, swelling, and discomfort. This dual action helps clear existing plaques and prevents new ones from forming.
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Alcohol

Unsafe

Zoratame 10mg Capsule may interact with alcohol and increase the risk of side effects. So, it is not recommended to take alcohol, especially women of childbearing potential, during the treatment and at least 2 months after completing the treatment.

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Pregnancy

Unsafe

Zoratame 10mg Capsule should not be used in pregnant women as it may cause harmful effects to the unborn baby or fetus. Consult your doctor for further advice.

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Breast Feeding

Unsafe

Zoratame 10mg Capsule should not be given to breastfeeding mothers as it may pass into breast milk and harm the nursing baby. Consult your doctor for further advice.

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Driving

Unsafe

Zoratame 10mg Capsule may suddenly cause vision problems, especially in the dark. So, do not drive or operate heavy machinery if you notice any vision problems, especially at night.

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Liver

Caution

Zoratame 10mg Capsule should not be used in patients with severe liver failure, as Zoratame 10mg Capsule may cause liver damage. In mild to moderate liver disease, your doctor may need to adjust the dose.

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Kidney

Caution

Zoratame 10mg Capsule should not be used in patients with severe kidney failure. In mild to moderate kidney disease, your doctor may need to adjust the dose.

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Children

Caution

Zoratame 10mg Capsule should be used in children only if clinically needed, as it may affect growth and bone development. The dose may have to be adjusted by your doctor.

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Heart

Caution

Zoratame 10mg Capsule should be taken with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Zoratame 10mg Capsule.

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Geriatrics

Caution

Zoratame 10mg Capsule can be given in elderly patients with extreme caution due to the risk of increased side effects

What if I have taken an overdose of Zoratame 10mg Capsule

If you accidentally take too much of Zoratame 10mg Capsule, seek immediate medical attention. Symptoms of an overdose may include severe headache, dizziness, vomiting, or extreme dry skin and lips.

Diet & Lifestyle Advise

  • Moisturise Frequently: Use thick, fragrance-free ointments or creams on your skin and petroleum jelly on your lips to combat the intense dryness caused by Zoratame 10mg Capsule.
  • Protect Yourself from the Sun: This medicine makes your skin highly sensitive to sunlight. Wear protective clothing and wide-brimmed hats, and apply a broad-spectrum sunscreen with SPF 30 or higher daily. Avoid tanning beds.
  • Avoid Vitamin A Supplements: Do not take multivitamins or supplements containing vitamin A, as this can increase the risk of severe side effects from toxic buildup.
  • Stay Hydrated: Drink plenty of water throughout the day to help manage dry mouth, dry eyes, and skin dehydration.
  • Choose Gentle Skin Care: Avoid harsh soaps, scrubs, or chemical peels, which can severely irritate your already sensitive and thinning skin.
health query

Have a query?

How Soon It Starts Working

  • The time required for Zoratame 10mg Capsule to start working: The time required for Zoratame 10mg Capsule to show its effect is unknown.
  • The time for which the effects of Zoratame 10mg Capsule last: The duration of action for Zoratame 10mg Capsule is unknown.

What if you forget to take Zoratame 10mg Capsule

If you miss a dose of Zoratame 10mg Capsule, take it as soon as you remember, with food, on that same day. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Keep the capsules at room temperature, ideally between 15°C and 25°C (59°F to 77°F). •Store the medicine in its original container to protect it from light and moisture. Do not store it in the bathroom.

Drug Warnings

  • Strict Pregnancy Warning: Absolutely do not use Zoratame 10mg Capsule if you are pregnant or planning to become pregnant. If you are of childbearing age, you must use two highly effective forms of birth control simultaneously for at least one month before starting, during the entire treatment, and for three full years after stopping.
  • Do Not Donate Blood: You must not donate blood while taking Zoratame 10mg Capsule and for three years after your last dose. This prevents the medicine from being passed to a pregnant woman through a blood transfusion.
  • Avoid Alcohol Completely: Do not drink alcohol in any form during treatment and for two months after stopping. Alcohol causes the medicine to convert into a compound that stays in your body even longer, raising the risk of birth defects.
  • Avoid Night Driving: This medicine can affect your night vision. Be extremely cautious or avoid driving at night until you know how the treatment affects your eyes.
  • Monitor Your Labs: Attend all scheduled appointments for blood tests. Your doctor will need to monitor your liver function and cholesterol/lipid levels regularly while you take this medication.

Drug-Drug Interactions

verifiedApollotooltip
  • Methotrexate: May increase the risk of liver damage when combined with Zoratame 10mg Capsule.
  • Tetracyclines: May increase the risk of increased pressure inside the skull, leading to severe headaches and vision changes.
  • Vitamin A Supplements: May cause toxic build-up and severe side effects similar to vitamin A overdose.
  • Low-dose Progestin Contraceptives: The effectiveness of 'mini-pills' may be reduced, increasing the risk of pregnancy.
AcitretinTetracycline
Critical
AcitretinEtonogestrel
Critical

Drug-Drug Interactions

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AcitretinTetracycline
Critical
How does the drug interact with Zoratame 10mg Capsule:
Coadministration of Zoratame 10mg Capsule with Tetracycline can increase the risk and severity of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Zoratame 10mg Capsule with Tetracycline together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinEtonogestrel
Critical
How does the drug interact with Zoratame 10mg Capsule:
Coadministration of Zoratame 10mg Capsule with Etonogestrel can increase the risk and severity of birth defects when taken in pregnant women.

How to manage the interaction:
Taking Zoratame 10mg Capsule with Etonogestrel together is generally avoided as it can result in an interaction which can be serious, it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
AcitretinDemeclocycline
Critical
How does the drug interact with Zoratame 10mg Capsule:
Coadministration of Zoratame 10mg Capsule with Demeclocycline can increase the risk and severity of pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Zoratame 10mg Capsule with Demeclocycline together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinLevonorgestrel
Critical
How does the drug interact with Zoratame 10mg Capsule:
Coadministration of Zoratame 10mg Capsule with Levonorgestrel can increase the risk and severity of birth defects in unborn when taken by a pregnant woman.

How to manage the interaction:
Taking Zoratame 10mg Capsule with Levonorgestrel together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Never use Zoratame 10mg Capsule if you are pregnant. Do not stop using any medications without talking to a doctor.
AcitretinMinocycline
Critical
How does the drug interact with Zoratame 10mg Capsule:
Co-administration of Zoratame 10mg Capsule with Minocycline may increase the risk of a serious condition called pseudomotor cerebral (false brain tumour).

How to manage the interaction:
There's a possible interaction between Zoratame 10mg Capsule and Minocycline should be used together only if prescribed by a doctor. However, if you develop symptoms such as nausea, vomiting, headache, or visual disturbances during treatment with either medication, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
AcitretinOxytetracycline
Critical
How does the drug interact with Zoratame 10mg Capsule:
Co-administration of Zoratame 10mg Capsule with Oxytetracycline can increase the risk of a rare and serious condition called pseudotumor cerebri (caused by increased pressure in the brain).

How to manage the interaction:
Taking Zoratame 10mg Capsule with Oxytetracycline together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinMedroxyprogesterone
Critical
How does the drug interact with Zoratame 10mg Capsule:
Coadministration of Zoratame 10mg Capsule with Medroxyprogesterone can increase the risk and severity of birth defects when taken by a pregnant woman.

How to manage the interaction:
Taking Zoratame 10mg Capsule with Medroxyprogesterone together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. Consult a doctor if you get pregnant while taking these medications. Do not discontinue any medications without consulting a doctor.
AcitretinDoxycycline
Critical
How does the drug interact with Zoratame 10mg Capsule:
Coadministration of Zoratame 10mg Capsule with Doxycycline can increase the risk and severity of vision problems.

How to manage the interaction:
Taking Zoratame 10mg Capsule with Doxycycline together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinEthanol
Critical
How does the drug interact with Zoratame 10mg Capsule:
Coadministration of Zoratame 10mg Capsule with Ethanol can increase the risk and severity of birth defects.

How to manage the interaction:
Taking Zoratame 10mg Capsule with Ethanol together is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcitretinLeflunomide
Severe
How does the drug interact with Zoratame 10mg Capsule:
Coadministration of Zoratame 10mg Capsule with Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is an interaction between Zoratame 10mg Capsule and Leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • High-Fat Meals: Significantly increase the absorption and effectiveness of Zoratame 10mg Capsule in your body.
  • Alcohol: Must be avoided entirely, as it creates a harmful substance in your body that takes years to clear.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[RETINOIDS]

FAQs

Zoratame 10mg Capsule is used to treat psoriasis, an autoimmune (immune system attacks healthy cells) skin disorder characterised by scaly, swollen, and itchy skin.
Zoratame 10mg Capsule contains Acitretin, which belongs to the class of retinoids and is used to treat severe psoriasis. It has anti-inflammatory action and reduces the rashes, redness, scaling, and thickness. It also has antiproliferative properties and slows disease progression by slowing skin cell growth.
Zoratame 10mg Capsule may suddenly cause vision problems, especially in the dark. So, inform your doctor immediately if you experience vision problems. Also, refrain from activities such as driving or operating heavy machinery if you have vision problems.
Zoratame 10mg Capsule may not affect your immune system. It is not an immunosuppressant. It controls psoriasis by slowing its progression.
Zoratame 10mg Capsule may affect blood glucose levels and should be used with caution in patients with diabetes. You may have to regularly monitor blood glucose levels while using this medicine.
No, Zoratame 10mg Capsule is not an immunosuppressant. It belongs to the class of retinoids used to treat psoriasis.
Zoratame 10mg Capsule may cause foetal harm; so, do not take Zoratame 10mg Capsule if you are pregnant or plan to become pregnant within the next 3 years. Zoratame 10mg Capsule may cause liver damage. Inform the doctor if you have or have ever had liver disease. Consult your doctor immediately if you experience symptoms of liver damage, such as nausea, vomiting, upper right abdominal pain, loss of appetite, yellowing of the skin or eyes, or dark urine.
Zoratame 10mg Capsule may not affect semen. However, a small amount of Zoratame 10mg Capsule is present in the semen of male patients who take this medication. Though it is not known if this affects the foetus, talk to your doctor about the risks of taking Zoratame 10mg Capsule if your partner is pregnant or plans to become pregnant.
Take Zoratame 10mg Capsule with the main meal. It should be swallowed as a whole with water; do not crush or chew it.
Avoid becoming pregnant and alcohol consumption during treatment with Zoratame 10mg Capsule as it might affect the foetus. Do not donate blood while taking Zoratame 10mg Capsule and for 3 years after treatment. Zoratame 10mg Capsule may cause blurred vision; so, do not drive or operate machinery unless you are alert. Zoratame 10mg Capsule may make your skin sensitive to sunlight; therefore, avoid prolonged exposure.
You must wait at least three years after stopping Zoratame 10mg Capsule before trying to get pregnant. The medicine remains in your body's tissues for a very long time and can cause severe birth defects if you conceive during this period. Always use two reliable forms of birth control and talk to your doctor before planning a pregnancy.
When you mix alcohol with Zoratame 10mg Capsule, it causes your body to create a chemical that takes years to leave your body and can cause severe birth defects long after you stop the medicine. You must avoid alcohol entirely during treatment and for two months after your last dose. Talk to your doctor if you need help avoiding alcohol.
No, you must not donate blood while taking Zoratame 10mg Capsule and for three years after stopping. If your donated blood is given to a pregnant woman, it could cause severe birth defects in her baby. Talk to your doctor or pharmacist if you have questions about this restriction.
Yes, mild hair thinning or temporary hair loss is a common side effect of Zoratame 10mg Capsule. In most cases, this hair loss is temporary, and your hair should return to normal after you finish your treatment. If you are concerned about hair thinning, talk to your doctor.
Your doctor will order regular blood tests to check your liver health and measure the levels of fats (cholesterol and triglycerides) in your blood. This medicine can sometimes affect liver function and increase blood fat levels, which your doctor needs to monitor to keep you safe. Talk to your doctor about your lab schedule.
No, you should avoid taking vitamin A supplements or multivitamins that contain vitamin A while using Zoratame 10mg Capsule. Because this medicine is closely related to vitamin A, combining them can lead to a toxic buildup in your body, causing severe side effects. Talk to your doctor or pharmacist before taking any new supplements.
Dry skin and lips are very common during this treatment. You can manage this by applying thick, fragrance-free moisturisers and lip balms frequently throughout the day. Avoid hot showers and harsh soaps that can strip your skin of moisture. If the dryness becomes unmanageable or painful, talk to your doctor.

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Country of origin

India
Other Info - ZO64743
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