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compositionComposition:ALFUZOSIN-10MG
prescription
Prescription Medicine
info
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ZYALFA TABLET is used to treat the symptoms of Benign prostatic hypertrophy (enlarged prostate gland). It contains Afluzosin, which relaxes the muscles of the bladder and prostate; this reduces the narrowing of the urethra. Thereby, helps in relieving the symptoms of benign prostatic hyperplasia (BPH) and makes it easier to pass urine.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ALFUZOSIN-10MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About ZYALFA TABLET

ZYALFA TABLET is a prescription medication primarily used to treat the symptoms of an enlarged prostate, a condition known as benign prostatic hyperplasia. It belongs to a class of medicines that help relax the muscles in the prostate and bladder neck, making it much easier to urinate. This medication is specifically designed for adult men experiencing urinary difficulties due to prostate enlargement.

You should take this medicine once daily, consistently at the same time each day. It is highly important to take ZYALFA TABLET immediately after the same meal every day, as taking it on an empty stomach significantly reduces how much medicine your body absorbs. Along with taking your medication, limiting your intake of caffeine and alcohol can help improve your overall urinary symptoms.

While taking ZYALFA TABLET, some people may experience mild side effects like dizziness, headache, or tiredness. However, if you experience serious side effects such as chest pain, a sudden feeling of being faint, or a painful erection that lasts for several hours, you must seek medical attention immediately.

Do not take this if you have moderate to severe liver damage, as your body will not be able to process the medicine safely. Before starting this medication, talk to your doctor if you have severe kidney problems, a history of heart disease, or a condition that causes low blood pressure. This medicine is not approved for use in women or children.

This medicine can interact with other treatments, especially drugs used to lower blood pressure or treat erectile dysfunction, which can cause a dangerous drop in blood pressure. You should avoid drinking alcohol while taking this medicine, as it can worsen dizziness and lightheadedness. Elderly individuals should use this medicine with caution, as they may be more sensitive to its blood pressure-lowering effects.

Uses of ZYALFA TABLET

ZYALFA TABLET is used to treat benign prostatic hyperplasia. The detailed uses of ZYALFA TABLET are as follows:

  • Benign Prostatic Hyperplasia (BPH): ZYALFA TABLET is prescribed to treat the physical symptoms of an enlarged prostate in men. It works by relaxing the muscular tissues of the prostate gland and the bladder exit, which reduces the urinary blockage and improves the overall flow of urine.

Key Benefits

ZYALFA TABLET helps relieve the symptoms of an enlarged prostate by improving urine flow and reducing urinary discomfort. By relaxing the muscles around the prostate and bladder outlet, it supports easier urination and improves overall quality of life.

  • Helps Improve Urinary Flow: By relaxing the muscles of the prostate and bladder neck, ZYALFA TABLET helps improve urine flow, making urination easier and reducing straining.
  • Reduces Frequent and Night-Time Urination: ZYALFA TABLET helps decrease the urgent and frequent need to urinate, particularly during the night, promoting more restful sleep and greater daytime comfort.
  • Supports Better Bladder Emptying: By improving bladder emptying, ZYALFA TABLET helps reduce the sensation of incomplete urination, post-urination dribbling, and lower abdominal discomfort, allowing you to carry out your daily activities more comfortably.
Side effects of Zyalfa Tablet
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Apply a hot/cold pack to the affected area.
  • Doing gentle exercises can help cope with pain by stretching muscles.
  • Get enough sleep. It helps enhance mood and lower pain sensitivity.
  • Avoid alcohol, smoking and tobacco as they can increase pain.
  • Follow a well-balanced meal.
  • Meditation and massages may also help with pain.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Quit smoking as smoking impairs erectile function by significantly damaging blood vessels.
  • Maintain a healthy weight as overweight can cause erectile dysfunction.
  • Exercise regularly as physical activity enhances blood flow and overall health, benefiting erectile function.
  • Consume a healthy diet loaded with whole grains, fruits and vegetables.
  • Limit alcohol consumption as excessive alcohol intake can impair erectile function.
  • Manage stress by practicing techniques such as yoga, relaxation exercises or meditation.
  • In case erectile dysfunction is due to psychological factors, consider couple counselling or sex therapy to address relationship and anxiety issues.
  • Openly discuss your concerns with your partner.

Directions for Use

  • ZYALFA TABLET should be taken with food or as advised by a doctor.
  • Take ZYALFA TABLET once daily with the same meal each day as advised by a doctor.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How ZYALFA TABLET Works

ZYALFA TABLET contains alfuzosin, which works as a selective alpha-1 blocker. Inside your body, there are specific receptors called alpha-1 receptors located in the smooth muscle walls of the prostate gland and the neck of the bladder. When these receptors are stimulated, they cause the muscles to tighten, squeezing the urethra and blocking the passage of urine. By selectively blocking these receptors, ZYALFA TABLET relaxes these specific smooth muscles. This relaxation widens the urinary channel, allowing urine to flow out of the bladder more freely and with much less physical resistance, without affecting the ability of the bladder itself to contract and empty.
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Alcohol

Unsafe

You are recommended to avoid or limit alcohol consumption while taking ZYALFA TABLET as it may cause increased dizziness.

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Pregnancy

Not applicable

ZYALFA TABLET belongs to pregnancy category B. ZYALFA TABLET is intended for use in men only; women should not take ZYALFA TABLET, especially pregnant women.

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Breast Feeding

Not applicable

ZYALFA TABLET is intended for use in men only; women should not take ZYALFA TABLET.

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Driving

Caution

ZYALFA TABLET may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

ZYALFA TABLET should not be used if you have moderate to severe liver impairment. The safety of ZYALFA TABLET in patients with mild hepatic impairment has not been established. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

ZYALFA TABLET should not be given to children as safety and efficacy have not been established.

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Heart

Consult your doctor

Limited information is available; please consult your doctor.

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Geriatrics

Consult your doctor

Limited information available for use of ZYALFA TABLET in elderly patients. Please consult your doctor.

What if I have taken an overdose of ZYALFA TABLET

If you take more than your prescribed dose, you may experience severe dizziness, a rapid heartbeat, or fainting. Seek emergency medical attention immediately.

Diet & Lifestyle Advise

  • Manage your fluid intake: Avoid drinking large amounts of liquids in the late afternoon and evening to reduce the number of times you need to wake up at night to urinate.
  • Limit bladder irritants: Cut down on beverages containing caffeine or alcohol, as they can irritate your bladder and worsen urinary urgency.
  • Practise double voiding: When you urinate, wait a moment or two after you finish and try to urinate again. This helps ensure your bladder is completely empty.
  • Avoid cold environments: Cold weather can sometimes cause urinary retention or worsen symptoms of an enlarged prostate. Dress warmly when temperatures drop.
     
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How Soon It Starts Working

  • The time required for ZYALFA TABLET to start to work: ZYALFA TABLET ideally shows its action within 8 hours after administration.
  • The time for which the effects of ZYALFA TABLET last: The effect of ZYALFA TABLET lasts for 24 hours.

What if you forget to take ZYALFA TABLET

If you miss a dose, take it immediately after your next meal. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take two doses at the same time to make up for a missed one.

Storage

•Store ZYALFA TABLET tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the medication in its original container to protect it from direct light and moisture.

Drug Warnings

  • Always rise slowly from a sitting or lying position, especially when you first start taking ZYALFA TABLET, to prevent dizziness and falls.
  • Do not drive, operate heavy machinery, or perform hazardous tasks until you know how this medication affects your alertness.
  • If you are scheduled to undergo cataract or glaucoma eye surgery, tell your eye surgeon well in advance that you are taking ZYALFA TABLET, as it can cause a complication known as floppy iris syndrome during the procedure.
  • Never take this medication on an empty stomach, as food is required for the tablet to release and absorb properly in your body.

Drug-Drug Interactions

verifiedApollotooltip
  • Erectile Dysfunction Medications: Taking ZYALFA TABLET with PDE5 inhibitors (such as sildenafil or tadalafil) may increase the risk of low blood pressure, leading to severe dizziness or fainting.
  • Blood Pressure Medications: Combining this medicine with other drugs that lower blood pressure, including beta-blockers or other alpha-blockers, can cause an additive blood pressure-lowering effect.
  • Strong CYP3A4 Inhibitors: Medications such as ketoconazole, itraconazole, or ritonavir can significantly increase the levels of ZYALFA TABLET in your blood, raising the risk of severe side effects.
AlfuzosinVoriconazole
Critical
AlfuzosinThioridazine
Critical

Drug-Drug Interactions

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AlfuzosinVoriconazole
Critical
How does the drug interact with Zyalfa Tablet:
Using Zyalfa Tablet together with voriconazole may significantly increase the blood levels and effects of Zyalfa Tablet.

How to manage the interaction:
Taking Voriconazole with Zyalfa Tablet is not recommended, please consult a doctor before taking it. Call a doctor if you experience dizziness, headache, nasal congestion, or heart palpitation. Do not stop using any medications without talking to a doctor.
AlfuzosinThioridazine
Critical
How does the drug interact with Zyalfa Tablet:
Taking Zyalfa Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Zyalfa Tablet with Thioridazine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinClarithromycin
Critical
How does the drug interact with Zyalfa Tablet:
When Zyalfa Tablet and Clarithromycin can increase the risk or severity of side effects like low blood pressure or irregular heart rates.

How to manage the interaction:
Taking clarithromycin with Zyalfa Tablet is not recommended as it can result in an interaction; it should be taken only if your doctor has advised it. However, if you experience dizziness, headache, palpitations, or chest discomfort, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinDronedarone
Critical
How does the drug interact with Zyalfa Tablet:
Coadministration of Dronedarone with Zyalfa Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dronedarone with Zyalfa Tablet together is not recommended, as it leads to an interaction, it can be taken if your doctor has advised it. However, if you experience dizziness, shortness of breath, chest discomfort, or palpitations, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinCeritinib
Critical
How does the drug interact with Zyalfa Tablet:
Coadministration of Zyalfa Tablet and ceritinib can increase the risk of developing side effects.

How to manage the interaction:
Taking Ceritinib with Zyalfa Tablet is not recommended as it can result in an interaction; it should be taken only if your doctor has advised it. However, if you experience dizziness, headache, palpitations, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinTelaprevir
Critical
How does the drug interact with Zyalfa Tablet:
Taking Telaprevir with Zyalfa Tablet can increase the blood levels and effects of Zyalfa Tablet. This can increase the risk or severity of low blood pressure.

How to manage the interaction:
Taking Telaprevir with Zyalfa Tablet is not recommended as it can possibly result in an interaction, it can be taken only if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinIdelalisib
Critical
How does the drug interact with Zyalfa Tablet:
When Idelalisib is taken with Zyalfa Tablet, it can lower the metabolism of Zyalfa Tablet. This can increase the risk or severity of side effects like low blood pressure.

How to manage the interaction:
Taking Zyalfa Tablet with Idelalisib is not recommended as it can possibly result in an interaction, it should be taken only if your doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, headache, flushing, nasal congestion, heart palpitation, and priapism (prolonged and painful erection), contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinKetoconazole
Critical
How does the drug interact with Zyalfa Tablet:
Using Zyalfa Tablet together with ketoconazole may significantly increase the blood levels of Zyalfa Tablet, which may result in side effects.

How to manage the interaction:
Taking Zyalfa Tablet with Ketoconazole is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fainting, headache, flushing, nasal congestion, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AlfuzosinAtazanavir
Critical
How does the drug interact with Zyalfa Tablet:
Concomitant use of Zyalfa Tablet with Atazanavir can increase the risk of low blood pressure.

How to manage the interaction:
Coadministration of Zyalfa Tablet with Atazanavir is not recommended, however, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience dizziness, palpitations, difficulty swallowing, or sweating. It is recommended to monitor your blood pressure regularly. Do not discontinue any medications without first consulting your doctor.
AlfuzosinErythromycin
Critical
How does the drug interact with Zyalfa Tablet:
When Zyalfa Tablet is taken with erythromycin, this can cause your blood pressure to fall excessively and your heart rate to increase, especially when you rise from a sitting or lying position.

How to manage the interaction:
Taking erythromycin with Zyalfa Tablet is not recommended as it can result in an interaction, but it should be taken if your doctor has advised it. However, if you experience dizziness, headache, or shortness of breath, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Empty Stomach: Taking this medication without food drastically reduces its absorption by about 50%, making the treatment much less effective.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[BPH AGENTS]

FAQs

ZYALFA TABLET is used to treat the symptoms of benign prostatic hypertrophy.
ZYALFA TABLET works by relaxing the muscles of the bladder and prostate; this reduces the narrowing of the urethra. It thereby helps in relieving the symptoms of benign prostatic hyperplasia and makes it easier to pass urine.
Dry mouth could be a side effect of ZYALFA TABLET. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy may help stimulate saliva and thereby prevent mouth dryness.
Diarrhoea might be a side-effect of ZYALFA TABLET. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.
Orthostatic hypotension, also known as postural hypotension, could be a side-effect of ZYALFA TABLET. Postural hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead, lie down and get up slowly only when you feel better.
Talk to your doctor before taking ZYALFA TABLET with anti-fungal medicines such as ketoconazole and itraconazole, and antiretroviral medicines such as ritonavir, as they might increase the blood levels of ZYALFA TABLET.
Prostatic carcinoma is the cancer of the prostate gland, whereas benign prostatic hyperplasia is the non-cancerous growth of the prostate. Prostatic carcinoma and benign prostatic hyperplasia may have the same symptoms. Therefore, people with benign prostatic hyperplasia should be examined prior to starting the treatment with ZYALFA TABLET to rule out the presence of carcinoma of the prostate.
If you are due to have or are undergoing cataract surgery, inform the doctor that you are taking ZYALFA TABLET. This will help the doctor manage the complications in advance, which could occur during the surgery.
Consult your doctor before taking ZYALFA TABLET with nitrates. Taking ZYALFA TABLET with medicines used to treat angina/chest pain, such as nitrates (nitroglycerin, glyceryl trinitrate), may cause severe lowering of blood pressure.
ZYALFA TABLET does not shrink the prostate. It belongs to the alpha-blocker class of drugs. It works by relaxing muscles in the bladder and prostate, allowing urine to flow more freely.
No, ZYALFA TABLET will not cause erectile dysfunction.
It is typically taken once a day, immediately after meals. The dose and duration should be followed as directed by the physician.
ZYALFA TABLET should not be used if you have moderate to severe liver impairment. The safety of ZYALFA TABLET in patients with mild hepatic impairment has not been established. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Yes, aged or elderly people can take ZYALFA TABLET, but they must exercise caution. Regular monitoring is essential.
While rare, ZYALFA TABLET can occasionally cause abnormal vision. Importantly, if you're scheduled for any eye surgery, including cataract surgery, inform your surgeon about your use of ZYALFA TABLET. This medication may require special considerations during the procedure
If you're taking ZYALFA TABLET and also plan to use sildenafil or vardenafil, don't do it without talking to your doctor first. Taking them together can cause your blood pressure to drop too low, which can be dangerous.
To help feel better while taking ZYALFA TABLET, follow your doctor's instructions, drink lots of water, avoid alcohol, eat healthy, get enough sleep, and tell your doctor if you have any new problems.
Common side effects of ZYALFA TABLET may include dizziness, nausea, vomiting, diarrhoea, stomach pain, headache, and dry mouth.
No, ZYALFA TABLET is not approved or intended for use in women. It is formulated specifically to treat urinary symptoms caused by an enlarged prostate in men. Talk to your doctor if you are seeking urinary treatments for women.
No, you must swallow the tablet whole. Crushing, chewing, or breaking the tablet destroys its extended-release design, which can cause too much medicine to enter your bloodstream all at once. Talk to your doctor or pharmacist if you have trouble swallowing tablets.
You should limit or avoid alcohol while taking this medicine. Alcohol can expand your blood vessels, which, when combined with ZYALFA TABLET, greatly increases the risk of severe dizziness, lightheadedness, and fainting. Talk to your doctor about safe alcohol limits.
Yes, ZYALFA TABLET can lower your blood pressure, especially when you stand up quickly. This is known as orthostatic hypotension and can make you feel dizzy or faint. Talk to your doctor if you are already taking medications for high blood pressure.

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Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - ZYA0001
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