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compositionComposition:OXYTOCIN-5I.U
prescription
Prescription Medicine
info
ZYGON INJECTION 1ML

ZYGON INJECTION 1ML is used for initiating or improving uterine contraction (antepartum) and producing uterine contraction during the third stage of labour (postpartum). Besides this, it also controls postpartum bleeding or haemorrhage after childbirth. It contains a synthetic female hormone, Oxytocin, which stimulates uterine muscles and increases the uterus contractions. It also increases the production of a natural substance called prostaglandins (PGs), increasing contractions and hence inducing labour. As a result, these increased uterine contractions help deliver the child. It may cause common side effects such as nausea, vomiting, and headache. Before taking this medicine, you should tell your doctor if you are allergic to any of its components and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

OXYTOCIN-5I.U

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About ZYGON INJECTION 1ML

ZYGON INJECTION 1ML is an injectable clinical solution used to initiate or improve uterine contractions during childbirth. Doctors use this medication to help start labour when medically necessary or to strengthen contractions during a slow delivery. It is also highly effective at controlling or preventing excessive bleeding after the baby is born.

Since ZYGON INJECTION 1ML is given as an injection directly into a vein or muscle, its use is carefully managed by healthcare professionals in a hospital setting. It is not a daily medication and is only given for specific, short-term medical needs during delivery. Because it is injected directly, food intake does not impact how it works, but staying well-hydrated during labour is highly recommended to support your body's natural response.

Some patients may experience mild side effects, such as nausea, vomiting, or a temporary change in heart rate. While these are often manageable, it is vital to tell your medical team immediately if you experience severe headaches, extreme dizziness, or sudden swelling, as these can point to more serious complications. Your healthcare provider will monitor you and your baby closely throughout the entire process to ensure safety.

Before receiving ZYGON INJECTION 1ML, tell your doctor if you have had a previous Caesarean section or pelvic surgery or if you have high blood pressure or heart problems. Do not take this if you have been told that a vaginal delivery is unsafe for you or the baby, or if you have an unusually shaped pelvis. It should also be avoided if the baby is in an abnormal position or is showing signs of distress before labour begins.

This medicine can interact with certain blood pressure medications and anaesthetics, which may cause sudden changes in your blood pressure levels. While it is naturally used during childbirth, if you are breastfeeding, let your doctor know so they can monitor your recovery. Elderly individuals do not typically receive this medication, as its use is strictly limited to obstetric care.

Uses of ZYGON INJECTION 1ML

ZYGON INJECTION 1ML is used to initiate or improve uterine contractions during childbirth. The detailed uses of ZYGON INJECTION 1ML are as follows:

  • Induction of labour: ZYGON INJECTION 1ML helps start contractions in pregnant women when labour does not begin naturally and there is a medical reason to proceed with delivery.
  • Strengthening labour contractions: It helps improve the frequency and strength of contractions when labour has slowed down or stalled during delivery.
  • Prevention and control of postpartum bleeding: It causes the uterus to contract after childbirth, which helps squeeze blood vessels and significantly reduces heavy bleeding.

Key Benefits

ZYGON INJECTION 1ML helps support the labour and delivery process by promoting effective uterine contractions. It is also used to help control bleeding after childbirth, supporting maternal safety and recovery.

  • Supports Progression of Labour: By stimulating coordinated uterine contractions, ZYGON INJECTION 1ML helps support the progression of labour when medically indicated, contributing to a safer and more effective delivery process.
  • Helps Reduce Excessive Bleeding After Childbirth: Following delivery, ZYGON INJECTION 1ML helps the uterus contract firmly, which can reduce blood loss and lower the risk of postpartum haemorrhage.
  • Supports Postpartum Recovery: By helping the uterus return to its normal size and maintain effective contractions after childbirth, ZYGON INJECTION 1ML supports a more stable recovery period and promotes maternal well-being in the immediate postpartum phase.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • ZYGON INJECTION 1ML will be administered by the doctor or healthcare professional.
  • Do not self-administer.

How ZYGON INJECTION 1ML Works

ZYGON INJECTION 1ML contains oxytocin. It works by mimicking a natural hormone in the body called oxytocin, which triggers the muscles of the uterus to contract. When injected into the bloodstream or muscle, it attaches to specific receptors on the uterine muscle cells, causing them to contract rhythmically, just as they would during natural labour. During delivery, these controlled contractions help dilate the cervix and gently push the baby down the birth canal. After delivery, the continued contractions caused by ZYGON INJECTION 1ML help compress the blood vessels where the placenta was attached, which effectively stops bleeding and helps the uterus begin its healing process.
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Alcohol

Unsafe

ZYGON INJECTION 1ML should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol.

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Pregnancy

Safe if prescribed

ZYGON INJECTION 1ML is used to induce contractions in the uterus so if given by the doctor for delivery it is safe.

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Breast Feeding

Caution

Inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing ZYGON INJECTION 1ML.

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Driving

Unsafe

ZYGON INJECTION 1ML can cause contraction of the uterus and lead to baby birth. So, driving a car may be highly unsafe.

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Liver

Caution

Inform the doctor before receiving the ZYGON INJECTION 1ML if you have had a Liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

Inform the doctor before receiving the ZYGON INJECTION 1ML if you have had a Kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Caution

ZYGON INJECTION 1ML is not recommended for children below the age of 18 years. The safety and effectiveness of ZYGON INJECTION 1ML have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

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Heart

Consult your doctor

Please consult your doctor before using ZYGON INJECTION 1ML if you have pre-existing heart problems. Your doctor will prescribe ZYGON INJECTION 1ML if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering ZYGON INJECTION 1ML to geriatric patients. Your doctor will prescribe ZYGON INJECTION 1ML if the benefits outweigh the risks.

What if I have taken an overdose of ZYGON INJECTION 1ML

Because your medical team will monitor you continuously during the injection, they can instantly adjust or stop the medication if your uterus contracts too strongly or if your baby shows signs of stress. If you suspect an issue, inform your healthcare provider immediately

Diet & Lifestyle Advise

  • Stay well-hydrated: Drink plenty of water before and after delivery to support your body's recovery and keep blood pressure stable.
  • Maintain a light diet: If permitted by your medical team before labour induction, consume light, easy-to-digest foods to keep your energy up without upsetting your stomach.
  • Rest as much as possible: After receiving the injection and completing delivery, prioritise rest to allow your uterine muscles to heal and recover naturally.

Have a query?

How Soon It Starts Working

The time required for ZYGON INJECTION 1ML to start to work: The time required for ZYGON INJECTION 1ML to show its action is unknown. The time for which the effects of ZYGON INJECTION 1ML last: The duration of action for ZYGON INJECTION 1ML is unknown.

What if you forget to take ZYGON INJECTION 1ML

Since this medication is given in a clinical setting by healthcare professionals according to a strict medical plan, it is highly unlikely that you will miss a dose.

Storage

•ZYGON INJECTION 1ML is stored in a controlled healthcare environment. •Depending on the manufacturer's guidelines, it is stored either in a refrigerator between 2°C and 8°C (do not freeze) or at controlled room temperature below 25°C.
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Keep Refrigerated. Do not freeze.

Drug Warnings

  • Ensure the solution is clear and colourless; do not use it if it contains particles or appears discoloured.
  • Your healthcare team will continuously monitor your uterine contractions and your baby's heart rate during the injection.
  • Inform your doctor immediately if you feel sudden, sharp pain in your pelvic area during the infusion.
  • Always use a sterile needle and syringe if your medical setup requires manual preparation, ensuring safe disposal in a sharps container.
  • Let your provider know if you have a history of asthma or severe allergies before receiving the injection.

Drug-Drug Interactions

verifiedApollotooltip
  • Anaesthetics (like cyclopropane or halothane): May cause a sudden drop in blood pressure or abnormal heart rhythms when used together with ZYGON INJECTION 1ML.
  • Blood pressure-raising medicines (vasopressors): Can lead to severe high blood pressure if taken together.
  • Prostaglandins: These medicines can increase the effect of ZYGON INJECTION 1ML, making contractions extremely strong. They should be used with extreme caution under close supervision.
OxytocinSparfloxacin
Critical
OxytocinGrepafloxacin
Critical

Drug-Drug Interactions

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OxytocinSparfloxacin
Critical
How does the drug interact with Zygon Injection 1ml:
Coadministration of Zygon Injection 1ml and sparfloxacin can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Zygon Injection 1ml with Sparfloxacin is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
OxytocinGrepafloxacin
Critical
How does the drug interact with Zygon Injection 1ml:
Coadministration of Zygon Injection 1ml with grepafloxacin can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Zygon Injection 1ml with Grepafloxacin is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
OxytocinDronedarone
Critical
How does the drug interact with Zygon Injection 1ml:
Taking Zygon Injection 1ml with dronedarone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Zygon Injection 1ml with Dronedarone is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
OxytocinHalofantrine
Critical
How does the drug interact with Zygon Injection 1ml:
Taking Zygon Injection 1ml with halofantrine can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Zygon Injection 1ml with Halofantrine is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
OxytocinZiprasidone
Critical
How does the drug interact with Zygon Injection 1ml:
Taking Zygon Injection 1ml with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Zygon Injection 1ml with Ziprasidone is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
OxytocinMesoridazine
Critical
How does the drug interact with Zygon Injection 1ml:
Using Zygon Injection 1ml together with mesoridazine can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Zygon Injection 1ml with Mesoridazine is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
OxytocinPimozide
Critical
How does the drug interact with Zygon Injection 1ml:
Coadministration of Zygon Injection 1ml with pimozide can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Pimozide with Zygon Injection 1ml is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
OxytocinCisapride
Critical
How does the drug interact with Zygon Injection 1ml:
Using Zygon Injection 1ml with cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Zygon Injection 1ml with cisapride is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
OxytocinThioridazine
Critical
How does the drug interact with Zygon Injection 1ml:
Taking Zygon Injection 1ml with thioridazine can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Zygon Injection 1ml with Thioridazine is not recommended, but should be taken if advised by a doctor. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
OxytocinIvabradine
Severe
How does the drug interact with Zygon Injection 1ml:
Taking Zygon Injection 1ml with ivabradine can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Zygon Injection 1ml and Ivabradine, you can take these medicines together if prescribed by your doctor. However, if you experience if you develop sudden dizziness, lightheadedness, fainting, or shortness of breath contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with ZYGON INJECTION 1ML when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[OXYTOCIC, UTEROTONIC, ECBOLIC]

FAQs

ZYGON INJECTION 1ML is used for initiating or improving uterine contraction (antepartum) and producing uterine contraction during the third stage of labour (postpartum). Besides this, it also controls postpartum bleeding or haemorrhage after childbirth.
ZYGON INJECTION 1ML when given in the intravenous form, labour induction stimulates uterine muscle contractions in the uterus. Also, it increases the production of prostaglandins, which further increases contractions and hence induces labour. As a result, these increased uterine contractions help deliver the child.
No, giving ZYGON INJECTION 1ML in the form of a rapid injection into a vein is not recommended as it might cause hypotension (low blood pressure) or suddenly increased heart rate. It should always be given as an intravenous infusion, and the doctor will monitor the speed.
If you have a previous premature delivery, a c-section, or cervical surgery, please inform your doctor before starting ZYGON INJECTION 1ML. Also, mention a detailed medical history to your doctor to avoid complications.
The most common side effects of ZYGON INJECTION 1ML include nausea, vomiting, headache, and increased blood pressure. You might also feel increased uterine contractions for some time, but these are manageable under medical supervision.
ZYGON INJECTION 1ML is given as an injection as an intravenous infusion at a hospital only under strict medical supervision. The dose to be administered will be decided by your doctor, depending upon your current medical situation.
Yes, healthcare providers often use ZYGON INJECTION 1ML to strengthen and increase the frequency of contractions when labour has stalled or is progressing too slowly. Talk to your doctor to understand if this is right for your delivery.
When used under close medical supervision with continuous monitoring of the baby's heart rate, ZYGON INJECTION 1ML is widely considered safe and effective. Talk to your doctor or pharmacist if you have concerns about its safety.
Because ZYGON INJECTION 1ML can make contractions stronger and more regular, some women find the contractions feel more intense than natural ones. Talk to your doctor about pain management options during labour.
Yes, it is commonly injected after delivery to help the uterus contract, which safely reduces the risk of heavy bleeding or postpartum haemorrhage. Talk to your doctor for more details.
The body breaks down the active oxytocin in ZYGON INJECTION 1ML very quickly, and its effects usually fade within an hour after the infusion is stopped. Talk to your doctor or pharmacist if you want to know more.
No, ZYGON INJECTION 1ML does not have known long-term side effects when used correctly during labour and delivery under medical supervision. Talk to your doctor if you experience any unusual symptoms after your recovery.
No, ZYGON INJECTION 1ML must be given as an injection (parenteral route) because stomach acids would break it down before it could work. Talk to your doctor or pharmacist for more information on how this medicine is given.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.9457 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  2. Drugs.com Clinical Review Team. Oxytocin Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026] Check here
  3. Electronic Medicines Compendium (EMC). Pil.9334 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026] Check here
  4. National Health Service (NHS). Inducing Labour - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026] Check here
  5. Oxytocin Oxytocin. 2013. [Accessed on 03 Apr. 2019] Check here
  6. Oxytocin Oxytocin. 2018. [Accessed on 03 Apr. 2019] Check here
  7. Oxytocin 10 IU/ml Concentrate for Solution for Infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [Accessed on 7 February 2022]Check here

Country of origin

India

Manufacturer/Marketer address

SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - ZYG0001

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