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Zyrcold Tablet is used to treat bronchitis, cough, and allergies. It contains Cetirizine and Ambroxol, which block the effects of a chemical messenger known as histamine, which is naturally involved in allergic reactions. Also, it thins and loosens mucus (phlegm), making it easier to cough out. In some cases, you may experience tiredness, sleepiness, dry mouth, etc. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Zyrcold Tablet

Zyrcold Tablet is a prescription combination medicine used to relieve productive cough associated with respiratory conditions where thick mucus and allergy symptoms may occur together. It helps loosen mucus from the airways while reducing allergy-related symptoms such as runny nose, sneezing, and itchy eyes.

For the best results, take Zyrcold Tablet regularly at the specific times recommended by your doctor. It can be taken with or without food, though taking it with a glass of water is helpful. Making simple lifestyle adjustments, such as increasing your daily water intake, can also support the medication's effectiveness in clearing respiratory mucus.

Some people may experience mild side effects, such as drowsiness, a dry mouth, or a mild upset stomach. While these are usually temporary, you should consult your doctor immediately if you notice serious symptoms, including a severe skin rash, swelling of the face, or difficulty breathing.

Do not take this medicine if you are allergic or hypersensitive to cetirizine, ambroxol, or any other ingredient in the formulation.

Inform your doctor if you have narrow-angle glaucoma, an enlarged prostate, urinary retention problems, or difficulty passing urine, as antihistamines may worsen these conditions in some individuals.

Consult your doctor before using Zyrcold Tablet during pregnancy. Ambroxol is generally avoided during the first trimester unless specifically considered necessary by a healthcare professional. Cetirizine may be considered when the expected benefits outweigh potential risks. 

Uses of Zyrcold Tablet

Zyrcold Tablet is used to treat respiratory issues. The detailed uses of Zyrcold Tablet are as follows:

  • Allergic respiratory congestion: Relieves allergy symptoms like runny nose, sneezing, and watery eyes that occur alongside respiratory congestion.
  • Productive cough with mucus: Helps loosen and clear thick mucus associated with respiratory infections, bronchitis, or other airway conditions.
     

Key Benefits

Zyrcold Tablet provides targeted relief that helps you return to your normal daily activities. It delivers several key benefits:

  • Dual-action relief: Targets both mucus buildup and allergy symptoms in a single tablet, helping reduce the need for multiple medicines.
  • Improves mucus clearance: Ambroxol helps loosen mucus and improves airway clearance, making phlegm easier to remove.
  • Relieves allergy-related discomfort: Cetirizine helps reduce symptoms such as sneezing, runny nose, and itchy eyes.
  • Supports easier breathing: By reducing mucus congestion and irritation, it may improve breathing comfort and daily activity.
     

Directions for Use

Follow these step-by-step instructions for taking this tablet:

  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break it, as this may affect how the medicine is released.
  • Take with or without food. If you experience mild stomach discomfort, taking the tablet with a meal may help.
  • For children: The safety and dosage depend on the child’s age, weight, and medical condition. This combination is generally not recommended for children below 2 years unless specifically prescribed by a doctor.
  • Always consult a doctor before giving this medicine to children.
  • Duration of treatment: This medicine is usually prescribed for short-term relief of acute cough and respiratory symptoms. Many acute conditions may require treatment for around 5–7 days, although the duration can vary depending on the cause and severity of symptoms. Ambroxol’s mucus-clearing benefits may become more noticeable during this treatment period rather than immediately after the first dose.
     

How Zyrcold Tablet Works

Zyrcold Tablet is a combination medicine that works through two active mechanisms to clear your airways and soothe irritation. Cetirizine is a second-generation antihistamine that generally causes less drowsiness compared with older first-generation antihistamines, although some people may still experience sleepiness. The second active ingredient, ambroxol, is a mucolytic and mucokinetic agent (a medicine that breaks down and helps move mucus). It chemically thins and breaks down thick, sticky mucus in the lungs and airways, making it less viscous and much easier to expel through coughing. This means it supports the natural process by which tiny hair-like cilia in the airways sweep mucus upward and out, making it easier to remove through coughing.
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Alcohol

Unsafe

It is not advised to consume alcohol while taking Zyrcold Tablet as it leads to excessive drowsiness.

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Pregnancy

Consult your doctor

If you are pregnant, inform your doctor before taking Zyrcold Tablet . Your doctor will weigh the benefits and risks before prescribing Zyrcold Tablet .

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Breast Feeding

Consult your doctor

Zyrcold Tablet is not recommended for use in breastfeeding. If you are a nursing mother, please inform your doctor before taking Zyrcold Tablet . Your doctor will weigh the benefits and risks before prescribing Zyrcold Tablet .

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Driving

Unsafe

Zyrcold Tablet may cause drowsiness. Avoid driving while you are on treatment with Zyrcold Tablet .

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Liver

Consult your doctor

Zyrcold Tablet should be taken with caution if you have liver disease. Please consult your doctor before taking it. Dose adjustments may be required.

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Kidney

Consult your doctor

Zyrcold Tablet should be taken with caution if you have kidney problems. Please consult your doctor before taking it. Dose adjustments may be required.

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Children

Caution

Zyrcold Tablet is not recommended for children under 6 years of age without a doctor's prescription. For children above 6, the dose should be adjusted and recommended by a child specialist only.

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Heart

Caution

Exercise caution before using Zyrcold Tablet in case of heart problems. Please consult your doctor if you have any concerns.

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Geriatrics

Caution

Zyrcold Tablet should be used with caution in elderly patients. Please consult your doctor before use.

What if I have taken an overdose of Zyrcold Tablet

Do not take more than the prescribed dose of Zyrcold Tablet as it may cause serious adverse effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Drink plenty of warm fluids, such as water, decaffeinated tea, or warm broths, to help thin the mucus in your airways.
  • Use a cool-mist humidifier in your room to add moisture to the air, which helps soothe dry and irritated nasal passages.
  • Avoid smoking and exposure to secondhand smoke, as tobacco smoke can worsen respiratory inflammation and mucus buildup.
  • Keep your living space free from dust and pollen by vacuuming regularly and keeping windows closed during high-pollen seasons.
     

Have a query?

How Soon It Starts Working

  • The time required for Zyrcold Tablet to start to work: Zyrcold Tablet ideally shows its action within 30 minutes after administration.
  • The time for which the effects of Zyrcold Tablet last: The duration of action for Zyrcold Tablet is unknown.

What if you forget to take Zyrcold Tablet

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next dose at the scheduled time. Do not take a double dose.

Storage

Store Zyrcold Tablet tablets at room temperature, ideally below 30°C (86°F), in a cool, dry place away from direct heat and moisture. •Keep the tablets in their original blister packaging to protect them from light. Do not store this medicine in the bathroom or f

Drug Warnings

  • Do not drive, operate machinery, or perform hazardous activities immediately after taking this medicine, as it may cause drowsiness or reduce your alertness.
  • Avoid consuming alcohol while taking Zyrcold Tablet , as it can worsen side effects like dizziness and sleepiness.
  • Check the blister pack before use; do not take the tablet if the packaging is broken, punctured, or shows signs of tampering.
  • If your cough persists for more than a few days, or if it is accompanied by a high fever, rash, or persistent headache, consult your doctor promptly.
  • Although cetirizine is less sedating than older antihistamines, some people may experience drowsiness.
  • Avoid driving or operating machinery until you know how this medicine affects you.
     

Drug-Drug Interactions

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Drug-Drug Interactions

Inform your doctor if you are taking any of the following medicines, as they may interact.

  • Zyrcold Tablet may interact with central nervous system depressants such as sedatives, sleeping medicines, muscle relaxants, anxiety medicines, or other medicines that cause drowsiness, increasing the risk of excessive sleepiness.
  • Ambroxol may also interact with certain medicines, including macrolide antibiotics such as azithromycin, which may increase ambroxol levels in the body.
  • Inform your doctor about all medicines you are taking before starting this treatment, including theophylline or other respiratory medicines, so your doctor can assess possible interactions and adjust treatment if needed.

Drug-Food Interactions

  • Avoid taking this medication with alcohol, as it can significantly intensify sleepiness and impair coordination.

Drug-Disease Interactions

Inform your doctor if you have a history of the following conditions before taking Zyrcold Tablet , as it may worsen your condition or cause complications.

  • Use with caution in people with kidney disease, as dose adjustment may be required. Avoid use in severe kidney impairment unless specifically advised by a doctor.
  • Use with caution if you have liver damage, or a history of peptic ulcers. 
     
Severe

Drug-Drug Interactions

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Severe
How does the drug interact with Zyrcold Tablet:
Co-administration of Zyrcold Tablet with esketamine may increase the side effects.

How to manage the interaction:
Although there is an interaction, Zyrcold Tablet can be taken with esketamine if prescribed by the doctor. Consult the prescriber if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIHISTAMINES/ANTIALLERGIC]

FAQs

No, Zyrcold Tablet is specifically formulated for a wet or productive cough to help thin and clear thick mucus. If you have a dry, ticklish cough without phlegm, this medication may not be suitable. Talk to your doctor to find the right treatment for your specific cough.

Zyrcold Tablet may cause drowsiness in some people, although cetirizine generally causes less sedation than older first-generation antihistamines. Avoid driving or operating machinery when starting this medicine until you know how it affects you. Talk to your doctor if excessive sleepiness occurs.

You should avoid taking other antihistamines while taking Zyrcold Tablet , as it already contains an active allergy reliever. Combining them could increase your risk of side effects like extreme drowsiness and dry mouth. Talk to your doctor or pharmacist before combining any over-the-counter allergy medications.

Cetirizine may begin reducing allergy symptoms such as sneezing, runny nose, and itching within about 1 hour in many people. Ambroxol’s mucus-clearing effects may develop gradually and become more noticeable with regular use over several days. The total duration of treatment depends on the cause and severity of symptoms and should be followed as advised by your doctor.

Talk to your doctor before taking this medicine during pregnancy. Ambroxol is generally not recommended during the first trimester, while use in later pregnancy may be considered if clinically appropriate. Cetirizine use should also be evaluated based on individual benefits and risks. Furthermore, during breastfeeding, ambroxol passes into breast milk, and patients should consult their doctor before use while nursing.

No, you should avoid drinking alcohol while taking this medicine. Alcohol can worsen side effects like drowsiness, dizziness, and lack of coordination. Talk to your doctor if you have concerns about managing this restriction.

You can take Zyrcold Tablet with or without food. If you have a sensitive stomach or experience mild nausea, taking the tablet with a meal or a small snack can help reduce stomach discomfort. Talk to your doctor if stomach irritation persists.

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular timing. Never take two tablets at once to make up for a missed dose. Talk to your doctor or pharmacist if you frequently miss doses.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

504, Peninsula Towers, Peninsula Corporate Park, Ganpatrao Kadam Marg, Lower Parel, IND - Mumbai 400 013
Other Info - ZYR0008
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