Zyrova B 40 Tablet 10's
MRP ₹464
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About Zyrova B 40 Tablet
Zyrova B 40 Tablet is used to lower the levels of bad cholesterol called low-density lipoprotein (LDL), a type of fat in the blood. This reduces the risk of heart attack and stroke in future. High cholesterol occurs when there is an excess of the unhealthy balance of cholesterol in the blood.
Zyrova B 40 Tablet is a combination of two drugs: Rosuvastatin and Bempedoic acid. Rosuvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Bempedoic acid decreases cholesterol production in the liver and increases the removal of LDL cholesterol from the blood.
Take Zyrova B 40 Tablet as prescribed. Your doctor will advise you how often you take Zyrova B 40 Tablet based on your medical condition. Zyrova B 40 Tablet may cause common side effects such as headache, stomach pain, dizziness, weakness, muscle pain or constipation. Most of these side effects of Zyrova B 40 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
If you are allergic to Rosuvastatin, Bempedoic acid or any other ingredients of Zyrova B 40 Tablet , please tell your doctor. If you are pregnant or breastfeeding, consult a doctor before taking Zyrova B 40 Tablet . Maintain a low-fat diet along with Zyrova B 40 Tablet for effective results.
Uses of Zyrova B 40 Tablet
Zyrova B 40 Tablet is used in the treatment of High cholesterol. The detailed uses of Zyrova B 40 Tablet are as follows:
- Lower LDL cholesterol: Zyrova B 40 Tablet is used to lower LDL cholesterol more effectively than either drug alone.
- Reduce the risk of cardiovascular events: Zyrova B 40 Tablet is used to reduce the risk of cardiovascular events like heart attacks and strokes.
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Directions for Use
- Zyrova B 40 Tablet can be taken with or without food, preferably at the same time each day.
- It is usually taken once daily or as prescribed by your doctor.
- Swallow Zyrova B 40 Tablet as a whole with a glass of water.
- Do not break, crush, or chew it.
Key Benefits
Zyrova B 40 Tablet belongs to the class of medicines called cholesterol-lowering agents. It contains Rosuvastatin, Bempedoic acid, and Ezetimibe. Rosuvastatin works by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart. Bempedoic acid decreases cholesterol production in the liver and increases the removal of LDL cholesterol from the blood.
How Zyrova B 40 Tablet Works
Storage
- Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
- Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
- Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
- Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
- Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
- Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
- Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.
- Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
- Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
- Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
- Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
- Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
- If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
- Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
- Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
- Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
- Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
- Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
- Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
- Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
- Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
- Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
- Monitor UTI symptoms and report any changes to your doctor.
- If antibiotics are prescribed, take them as directed and complete the full course.
What if I have taken an overdose of Zyrova B 40 Tablet
Drug Warnings
If you are allergic to Rosuvastatin, Bempedoic acid or any other ingredients of Zyrova B 40 Tablet , please tell your doctor. If you are pregnant or breastfeeding, consult a doctor before taking Zyrova B 40 Tablet . You are advised to take effective birth control measures to avoid pregnancy while taking Zyrova B 40 Tablet . Maintain a low-fat diet along with Zyrova B 40 Tablet for effective results. If you have diabetes, inform your doctor before taking Zyrova B 40 Tablet .
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of ciclosporin with Zyrova B 40 Tablet can increase blood levels of Zyrova B 40 Tablet. This can increase the risk of developing side effects.
How to manage the interaction:
Co-administration of cyclosporine and Zyrova B 40 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, light colour stools, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Zyrova B 40 Tablet and Darunavir can increase the blood levels of Zyrova B 40 Tablet and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).
How to manage the interaction:
Co-administration of Zyrova B 40 Tablet and Darunavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Zyrova B 40 Tablet and amprenavir can increase the blood levels of Zyrova B 40 Tablet and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).
How to manage the interaction:
Co-administration of Zyrova B 40 Tablet and Amprenavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of leflunomide and Zyrova B 40 Tablet can increase the risk of developing liver problems.
How to manage the interaction:
Co-administration of Leflunomide and Zyrova B 40 Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of Ritonavir and Zyrova B 40 Tablet can increase the blood levels of Zyrova B 40 Tablet.
How to manage the interaction:
Co-administration of Ritonavir and Zyrova B 40 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Saquinavir and Zyrova B 40 Tablet can increase the blood levels of Zyrova B 40 Tablet and can increase the risk of developing liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).
How to manage the interaction:
Co-administration of Saquinavir and Zyrova B 40 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Co-administration of Zyrova B 40 Tablet with lenalidomide may increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue).
How to manage the interaction:
Although there is an interaction between lenalidomide and Zyrova B 40 Tablet, it can be taken if prescribed by a doctor. However, if you experience muscle pain, tenderness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
Co-administration of Simeprevir and Zyrova B 40 Tablet can increase the blood levels of Zyrova B 40 Tablet and can increase the risk of side effects like liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).
How to manage the interaction:
Co-administration of Simeprevir and Zyrova B 40 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Coadministration of colchicine and Zyrova B 40 Tablet may increase the risk of conditions that affect your muscles and kidneys.
How to manage the interaction:
Taking Colchicine with Zyrova B 40 Tablet may possibly result in an interaction, but they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience abdominal discomfort, nausea, vomiting, diarrhea, back pain, weakness, or tingling or numbness in your hands and feet. Do not discontinue any medication without consulting your doctor.
Coadministration of Nicotinamide with Zyrova B 40 Tablet may increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage which can be fatal.
How to manage the interaction:
Taking Nicotinamide with Zyrova B 40 Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like unexplained muscle pain, muscle stiffness or tenderness, fever, dark-coloured urine, or weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
- Eat a healthy diet that includes fruits, vegetables, fish, poultry, whole grains, nuts, cut-down beverages, and processed and sugary foods.
- Do regular exercises such as swimming, cycling, walking, or dancing and focus on losing weight, as obesity also raises bad cholesterol and lowers good cholesterol.
- Avoid smoking and alcohol consumption.
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Alcohol
Safe if prescribed
If you regularly consume alcohol, consult your doctor before taking Zyrova B 40 Tablet .
Pregnancy
Consult your doctor
Zyrova B 40 Tablet is not recommended to take in pregnancy. If you become pregnant while using Zyrova B 40 Tablet , stop taking the medicine and inform your doctor.
Breast Feeding
Consult your doctor
It is not recommended to take Zyrova B 40 Tablet during breastfeeding. Consult your doctor for more information.
Driving
Safe if prescribed
Zyrova B 40 Tablet may sometimes cause dizziness. Drive only if you are alert after taking Zyrova B 40 Tablet .
Liver
Consult your doctor
If you have liver problems, inform your doctor before taking Zyrova B 40 Tablet . This medicine is not recommended in case of moderate to severe liver impairment.
Kidney
Consult your doctor
If you have kidney problems, inform your doctor before taking Zyrova B 40 Tablet . This medicine is not recommended in case of severe kidney impairment.
Children
Safe if prescribed
Safety and efficacy have not been established. Hence, please consult your doctor about using Zyrova B 40 Tablet in children.
Heart
Zyrova B 40 Tablet is often prescribed for heart patients to lower cholesterol and reduce cardiovascular risk. It should be taken only under medical supervision, with regular monitoring for side effects.
Geriatrics
Consult your doctor
Zyrova B 40 Tablet can be used by geriatric individuals, but with caution due to potential risks like muscle pain, liver enzyme elevation, or kidney issues. Always consult your doctor before use, as dose adjustments and regular monitoring may be necessary.
FAQs
Zyrova B 40 Tablet is used to lower the levels of bad cholesterol called low-density lipoprotein (LDL), a type of fat in the blood. This reduces the risk of heart attack and stroke in future.
Zyrova B 40 Tablet works by decreasing the production of LDL (bad cholesterol) by the liver and increases the removal of LDL cholesterol from the blood. Also, it reduces the risk of stroke or heart attack by reducing the excess cholesterol deposition in the major blood vessels of the brain and heart.
Zyrova B 40 Tablet should be used in diabetic patients only if the doctor advises, as it may increase blood sugar levels. Regular monitoring of blood sugar levels is recommended in diabetic patients, and inform your doctor before taking Zyrova B 40 Tablet if you are diabetic.
You are not recommended to stop taking Zyrova B 40 Tablet without consulting your doctor as it may worsen the condition and increase the risk of heart attack and stroke. Therefore, take Zyrova B 40 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Zyrova B 40 Tablet , please consult your doctor.
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Reference
- https://www.hpra.ie/img/uploaded/swedocuments/2173747.PA1380_202_002.89e39a70-3c35-4476-bace-bedda29872ed.000001Product%20Leaflet%20Approved.170407.pdf
- https://www.ema.europa.eu/en/documents/product-information/nilemdo-epar-product-information_en.pdf
- https://www.drugs.com/drug-interactions/rosuvastatin.html
- https://www.drugs.com/drug-interactions/bempedoic-acid.html
