NEBULA CH TABLET

Manufacturer : ZYD-ZYDUS
Composition : NEBIVOLOL-5MG+CHLORTHALIDONE-12.5MG
Dose Form : TABLET
Description : NEBULA CH TAB
Route Of Administration : ORAL
Pack : 10
Out of stock
SKU
NEB0156
₹109.00
Manufacturer : ZYD-ZYDUS
Composition : NEBIVOLOL-5MG+CHLORTHALIDONE-12.5MG
Dose Form : TABLET
Description : NEBULA CH TAB
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information

NEBIVOLOL-5MG+CHLORTHALIDONE-12.5MG

NEBIVOLOL

Information for patients
Drug Information Nebivolol contains nebivolol which is a selective beta blocker and it dilates blood vessels (vasodilator). It is used for the treatment of raised blood pressure (hypertension). Nebivolol is also used to treat chronic heart failure in patients aged 70 or over.
Drug Alert
Alert
Before Consuming the Medicine
Avoid Drug •if you are allergic (hypersensitive) to nebivolol or to any of the other ingredients of Nebivolol. •if you have low blood pressure (the systolic or “upper” pressure is less than 90 mmHg) •if you have poor circulation in the arms or legs •if you have a very slow heartbeat (less than 60 heart beats per minute before having started this medication) •if you have been diagnosed with conduction disorders in your heart (such as sick sinus syndrome or atrio-ventricular blockade) and you do not have a functioning pacemaker •if you have acute heart failure, or you are receiving treatment into a vein (by intravenous ‘drip’) to help your heart work •if you have difficulty in breathing or wheezing (or history of) •if you have a tumour of the adrenal gland called phaeochromocytoma •if you have severe liver disease or liver function impairment •if you have a metabolic acidosis (such as in diabetic patients when the blood sugar has risen too much and blood has become too acidic) •if you use either floctafenine or sultopride containing medications.
Drug Special Care -If you have or develop one of the following conditions: •heart failure (inability of heart to pump enough blood for body´s needs) •a mild (first degree) atrioventricular blockade in your heart •chest pain caused by cramping of the coronary arteries (called Prinzmetal´s angina or variant angina) •poor circulation in the arms or legs, e.g. Raynaud’s disease or syndrome, cramp-like pains on walking •prolonged breathing problems (or history of) •diabetes: Nebivolol has no effect on blood sugar, but it could mask the signs of a low sugar level (e.g. trembling, fast heartbeat). •overactive thyroid gland, as Nebivolol may mask the signs of an abnormally fast heart rate due to this condition •allergy, as the allergic reactions may become stronger and more medicines may be needed to treat them •a skin condition known as psoriasis, as Nebivolol\ may aggravate the symptoms •wear contact lenses, as Nebivolol may reduce lacrimation and make the eyes dryer. Use in children and adolescents below 18 years old is not recommended. In these cases, your doctor may need to adapt your treatment or check you more often. If you need to have an operation and need an anaesthetic, it is important that you tell the surgeon or dentist that you are taking this medicine. If you have kidney problems, do not take this medicine for heart failure and inform your doctor.
Drug Drug Interactions Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription, herbal remedies and strong vitamins and minerals. Always tell your doctor or pharmacist if you are using or receiving any of the following medicines in addition to Nebivolol: •diltiazem or verapamil (used for high blood pressure and other heart problems). During Nebivolol treatment, verapamil should not be injected into a vein •other medicinal products known as calcium channel blockers for high blood pressure or other heart problems such as amlodipine, felodipine, lacidipine, nifedipine, nicardipine, nimodipine, nitrendipine •other antihypertensive medications or organic nitrates to treat chest pain •clonidine, guanfacin, moxonidine, methyldopa, rilmenidine used for the treatment of high blood pressure •medicinal products for cardiac arrhythmias (irregular heartbeat) such as quinidine, hydroquinidine, amiodarone, cibenzoline, flecainide, disopyramide, lidocaine, mexiletine, propafenone •tricyclic antidepressants (for depression), phenothiazines (for psychoses), or barbiturates (for epilepsy) •medicinal products for diabetes mellitus (insulins and oral preparations) •digoxin or other so called digitalis glycosides (to treat heart failure) •anti-inflammatory analgesics (NSAIDs) for pain and inflammation- please note that small daily antithrombotic doses of acetylsalicylic acid (e.g., 50 or 100 mg) can be used safely with Nebivolol •medicinal products for asthma, blocked nose or certain eye disorders such as glaucoma (increased pressure in the eye) or dilation of the pupil •anaesthetics: always inform your anaesthetist that you are on Nebivolol before being anaesthetized •cimetidine (to treat excessive stomach acid)- you should take Nebivolol during a meal, and the antacid drug between meals •medicinal products affecting the metabolism of nebivolol namely terbinafine (for fungal or yeast infections), bupropion (to help in cessation of smoking), chloroquine (for malaria or rheumatoid arthritis), levomepromazine (for psychoses), paroxetine, fluoxetine, thioridiazine (for depression) •amifostine (a protecting substance during chemo- or radiation therapy) •baclofen (a muscle relaxant) •mefloquine (an antimalarial).
Drug Pregnancy Interaction Nebivolol should not be used during pregnancy unless instructed to do so by a doctor.
Drug Breast feeding Interaction Breast-feeding is not recommended during administration of Nebivolol.
Drug Machinery Interaction No studies on the effects on the ability to drive and use machines have been performed. This medicine may cause dizziness or fainting as a result to reduction in blood pressure. If these occur, DO NOT drive or operate machinery. These effects are more likely to occur after initiation of the treatment or after dose increases.
Drug More Information Nebivolol 5 mg tablets can be taken before, during or after a meal, but also you can take them without food. The tablet or its parts should be swallowed with some water or another liquid.
How to take the Medicine
Consumption Info
Drug quanitty Treatment of raised blood pressure (hypertension) •The usual dose is 1 tablet per day. •Elderly patients and patients with a kidney disorder will usually start with 1/2 tablet daily. •It may take up to 4 weeks for this medicine to have full effect. Treatment of chronic heart failure •Your treatment will be started and monitored by an experienced physician. •Your doctor will start your treatment with 1/4 tablet per day. This may be increased after 1-2 weeks to 1/2 tablet per day, then to 1 tablet per day and then to 2 tablets per day until the correct dose is reached for you. •The maximum recommended dose is 10 mg (2 tablets a day). •You will need to be monitored for 2 hours by an experienced physician when you start treatment and every time your dose is increased. •Your doctor may reduce your dose if necessary, and you should not stop abruptly as this can worsen heart failure. •Patients with serious kidney problems should not take this medicine.
Drug Dose Always take Nebivolol exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure.Take your medicine once daily, preferably at about the same time of day. Your doctor may decide to combine your tablets with other medicine for your condition. Nebivolol is not recommended in children and adolescents.
Excess Drug Consumption If you accidentally take too many tablets (overdose), you may experience slow heart beat, low blood pressure or other heart problems, or difficulty in breathing or wheezing. Contact your nearest hospital casualty department or tell your doctor or pharmacist immediately.
Forgot Drug Consumption If you forget to take your medicine, but remember to take it after a short time, take the next tablet normally, when it is the time to take it. However, if a long delay has occurred (e.g. all day) skip that dose and take the next dose the next day at the usual time and skip the forgotten dose. Do not take a double or a larger dose to make up with a forgotten dose (s). Repeated skipping is to be avoided.
Stop Drug Consumption Do not stop taking Nebivolol without consulting your doctor first. If the medication is terminated abruptly, the patient may experience dangerous worsening of the symptoms. This concerns especially the patients with angina pectoris.
Possible Side Effects
General Information
Common Drug Side Effects When used for raised blood pressure: •Headache •Dizziness •Tiredness •An unusual itching or tingling feeling •Diarrhoea •Constipation •Nausea •Shortness of breath •Swollen hands or feet
Rare Drug Side Effects when used for raised blood pressure: •Slow heartbeat or other heart complaints •Low blood pressure •Abnormal vision •Impotence (difficulty in getting an erection) •Depressive feelings •Indigestion, gas in stomach or bowel •Vomiting •Skin rash •Tightening of the chest, difficulty in breathing or wheezing •Nightmares •In a clinical study for chronic heart failure, the side effects seen were slow heart beat, dizziness, worsening of heart failure, low blood pressure (such as feeling faint when getting up quickly), inability to tolerate medicine, irregular heart beat, swelling (such as swollen ankles).
Very Rare Drug Side Effects •Fainting •Psoriasis aggravated
Drug Side Effects Symptoms •Angioedema: swelling of the skin of the face or extremities, lips, tongue, mucous membranes of the throat and airway, resulting in shortness of breath or difficulty to swallow – contact a doctor immediately! •Hypersensitivity
How to Store the Medicine
How to Store the Medicine Keep out of the reach and sight of children. Do not use Nebivolol after the expiry date which is stated on the carton after . The expiry date refers to the last day of that month. Do not store above 30°C. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

CHLORTHALIDONE

Information for patients
Drug Information This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Chlorthalidone is a "water pill" (diuretic) that causes your body to get rid of extra salt and water. This increases the amount of urine you make. This medication also reduces extra fluid in the body (edema) caused by conditions such as congestive heart failure, liver disease, and kidney disease. Getting rid of extra water helps to reduce fluid in the lungs so that you can breathe easier. It also helps to decrease swelling of the arms, legs, and stomach/abdomen. OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used to treat a condition known as "water diabetes" (diabetes insipidus) and to help prevent calcium kidney stones.
Drug Alert
Alert no data available
Before Consuming the Medicine
Avoid Drug Anuria. Known hypersensitivity to chlorthalidone or other sulfonamide-derived drugs.
Drug Special Care Before taking chlorthalidone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: severe kidney disease (inability to make urine). Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, untreated salt/mineral imbalance (e.g., imbalance of sodium, potassium, calcium, magnesium), loss of too much body water (dehydration), high levels of fats in the blood (high cholesterol/triglycerides), gout, lupus, certain recent nerve surgery (sympathectomy). If you have diabetes, chlorthalidone may affect your blood sugar levels. Check your blood sugar levels regularly as directed and share the results with your doctor. Tell your doctor immediately if you have symptoms of high blood sugar such as increased thirst/urination. Your doctor may need to adjust your anti-diabetic medication or diet. This drug may reduce the potassium levels in your blood. Ask your doctor about increasing the amount of potassium in your diet (e.g., bananas, orange juice) or about using a salt substitute containing potassium. A potassium supplement may be prescribed by your doctor. This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing when outdoors. Before having surgery, tell your doctor or dentist that you are taking this medication. This drug may make you dizzy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Significant loss of body water from too much sweating, vomiting, or diarrhea can also lower your blood pressure and worsen dizziness. Drink plenty of fluids to prevent these effects and dehydration. If you are on restricted fluid intake, consult your doctor for further instructions. Contact your doctor if you are unable to drink fluids or if you have persistent diarrhea/vomiting. Kidney function declines as you grow older. This medication is removed by the kidneys. Therefore, the elderly may be more sensitive to the effects of this drug, especially dizziness. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.
Drug Drug Interactions See also the How to Use section. Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first. This drug should not be used with the following medications because very serious interactions may occur: cisapride, dofetilide. If you are currently using any of these medications, tell your doctor or pharmacist before starting chlorthalidone. Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: corticosteroids (e.g., prednisone), diazoxide, digoxin, lithium, nonsteroidal anti-inflammatory drugs (e.g., ibuprofen, indomethacin), drugs that can increase dizziness (e.g., phenobarbital, narcotic pain relievers such as codeine). Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs-NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your blood pressure (e.g., pseudoephedrine, phenylephrine) or reduce the effect of this medication (e.g., ibuprofen, naproxen). Ask your pharmacist about the safe use of those products. Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day) should be continued. Consult your doctor or pharmacist for more details. This product can affect the results of certain lab tests. Make sure laboratory personnel and all your doctors know you use this drug. This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Drug Pregnancy Interaction This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
Drug Breast feeding Interaction This drug passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.
Drug Machinery Interaction This drug may make you dizzy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely
Drug More Information no data available
How to take the Medicine
Consumption Info no data available
Drug quanitty Hypertension Therapy in most patients should be initiated with a single daily dose of 15 mg. If the response is insufficient after a suitable trial, the dosage may be increased to 30 mg and then to a single daily dose of 45-50 mg. If additional control is required,the addition of a second antihypertensive drug is recommended. Increases in serum uric acid and decreases in serum potassium are dose-related over the 15-50 mg/day range and beyond. Edema INITIATION: Adults, initially 30 to 60 mg daily or 60 mg on alternate days. Some patients may require 90 to 120 mg at these intervals or up to 120 mg daily.Dosages above this level, however, do not usually produce a greater response. MAINTENANCE: Maintenance doses may often be lower than initial doses and should be adjusted according to the individual patient. Effectiveness is well sustained during continued use.
Drug Dose Take this medication by mouth with or without food, usually once daily or as directed by your doctor. It is best to avoid taking this medication within 4 hours of your bedtime to avoid having to get up to urinate. Consult your doctor or pharmacist if you have questions about your dosing schedule. The dosage is based on your medical condition and response to therapy. Use this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day or as prescribed. Do not increase your dose, skip doses, or stop taking this medication unless directed by your doctor. It is important to continue taking this medication even if you feel well. Most people with high blood pressure do not feel sick. For the treatment of high blood pressure, it may take up to several weeks before the full benefit of this drug takes effect. Cholestyramine and colestipol can decrease the absorption of this medication by your body. If you are taking either of these drugs, separate them from chlorthalidone by at least 4 hours. Inform your doctor if your condition does not improve or if it worsens (e.g., swelling increases, your routine blood pressure readings increase).
Excess Drug Consumption Dail 1066. OR Contact doctor immediately
Forgot Drug Consumption Contact Your doctor
Stop Drug Consumption Do not stop the drug untill your doctor says you to do so.
Possible Side Effects
General Information no data available
Common Drug Side Effects Dizziness, lightheadedness, headache, blurred vision, loss of appetite, stomach upset, diarrhea, or constipation may occur as your body adjusts to the medication. You may also experience decreased sexual ability or increased sensitivity to the sun. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may cause a loss of too much body water (dehydration) and salt/minerals. Tell your doctor immediately if you have any of these unlikely but serious symptoms of dehydration or mineral loss: very dry mouth, thirst, muscle cramps, weakness, fast/irregular heartbeat, nausea, vomiting, severe dizziness, unusual drowsiness, unusual decrease in the amount of urine, fainting, confusion, seizures. Tell your doctor immediately if any of these unlikely but serious side effects occur: numbness/tingling of the arms/legs, joint pain (e.g., big toe pain). Tell your doctor immediately if any of these rare but very serious side effects occur: signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding, stomach/abdominal pain, persistent nausea/vomiting, unusual/persistent tiredness, yellowing eyes/skin, dark urine, unusual change in the amount of urine (not including the normal increase in urine when you first start this drug). A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms no data available
How to Store the Medicine
How to Store the Medicine Store in a cool and dry place.

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