NIGRAIN PLUS TABLET

Manufacturer : UNI-UNI LAB INDIA PVT. LTD.
Composition : PROPRANOLOL-40MG+FLUNARIZINE-5MG
Dose Form : TABLET
Description : NIGRAIN PLUS TAB
Route Of Administration : ORAL
Pack : 10
Out of stock
SKU
NIG0011
₹60.00
Manufacturer : UNI-UNI LAB INDIA PVT. LTD.
Composition : PROPRANOLOL-40MG+FLUNARIZINE-5MG
Dose Form : TABLET
Description : NIGRAIN PLUS TAB
Route Of Administration : ORAL
Pack : 10

Drug Ingredient Information

PROPRANOLOL-40MG+FLUNARIZINE-5MG

PROPRANOLOL

Information for patients
Drug Information The name of your medicine is Propranolol hydrochloride.It has the active ingredient propranolol hydrochloride.This belongs to a group of medicines called beta-blockers.Propranolol hydrochloride is used for many conditions including: •High blood pressure (hypertension). •Chest pain (angina). •Preventing migraines. •Essential tremor (shaking with an unknown cause). •Anxiety. •Some thyroid problems (such as thyrotoxicosis which is caused by an overactive thyroid gland). •Bleeding in the food pipe (oesophagus) caused by high blood pressure in the liver. It works by the effects it has on the heart and circulation and also on other parts of the body.
Drug Alert
Alert •You have ever had asthma or wheezing. If this applies to you talk to your doctor or pharmacist. •You are allergic (hypersensitive) to propranolol hydrochloride or any of the other ingredients in Propranolol hydrochloride. •You have ever had any of the following heart problems: - heart failure which is not under control (this usually makes you breathless and causes your ankles to swell) - second- or third-degree heart block (a condition which may be treated by a pacemaker) - very slow or very uneven heart beats, very low blood pressure or very poor circulation - a type of chest pain (angina) called Prinzmetal’s angina. • You have a tumour called phaeochromocytoma that is not being treated. This is usually near your kidney and can cause high blood pressure. • You have been told that you have higher than normal levels of acid in your blood (metabolic acidosis). • You have been fasting recently. Do not take Propranolol hydrochloride if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Propranolol hydrochloride.
Before Consuming the Medicine
Avoid Drug •You have ever had asthma or wheezing. If this applies to you talk to your doctor or pharmacist. •You are allergic (hypersensitive) to propranolol hydrochloride or any of the other ingredients in Propranolol hydrochloride. •You have ever had any of the following heart problems: - heart failure which is not under control (this usually makes you breathless and causes your ankles to swell) - second- or third-degree heart block (a condition which may be treated by a pacemaker) - very slow or very uneven heart beats, very low blood pressure or very poor circulation - a type of chest pain (angina) called Prinzmetal’s angina. • You have a tumour called phaeochromocytoma that is not being treated. This is usually near your kidney and can cause high blood pressure. • You have been told that you have higher than normal levels of acid in your blood (metabolic acidosis). • You have been fasting recently. Do not take Propranolol hydrochloride if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Propranolol hydrochloride.
Drug Special Care Check with your doctor or pharmacist before taking Propranolol hydrochloride if: •You have ever had an allergic reaction, for example to insect stings. •You have poor blood circulation or controlled heart failure. •You have first-degree heart block. •You have sharp chest pain which is not caused by exercise (unstable angina). • You have problems with your kidneys. You may need to have some check-ups during your treatment. • You have problems with your liver (such as cirrhosis of the liver). You may need to have some check-ups during your treatment. • You have diabetes. Your medicine may change how you respond to having low blood sugar (hypoglycaemia). You may feel your heart beating faster. • You have thyrotoxicosis (a condition caused by an overactive thyroid gland). Your medicine may hide the symptoms of thyrotoxicosis. If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Propranolol hydrochloride.
Drug Drug Interactions Please tell your doctor or pharmacist if you are taking, or have recently taken, any other medicines. This includes medicines that you buy without a prescription and herbal medicines. This is because Propranolol hydrochloride can affect the way some other medicines work and some medicines can have aneffect on Propranolol hydrochloride. In particular, tell your doctor if you are taking any of the following medicines: •Clonidine (for high blood pressure or migraine). If you are taking clonidine and Propranolol hydrochloride together, do not stop taking clonidine unless your doctor tells you to do so. If you have to stop taking clonidine, your doctor will give you careful instructions about how to do it. •Verapamil, diltiazem, nifedipine,nisoldipine, nicardipine, isradipine or lacidipine (for high blood pressure or chest pain). •Disopyramide, lidocaine, quinidine, amiodarone or propafenone (for an uneven heart beat). •Digoxin (for heart problems). •Warfarin (to thin the blood). •Adrenaline, also known as epinephrine (a medicine that stimulates the heart). •Ibuprofen or indometacin (for pain and inflammation). •Ergotamine, dihydroergotamine or rizatriptan (for migraine). •Chlorpromazine or thioridazine (for mental illness). •Cimetidine (for stomach problems). •Rifampicin (for tuberculosis). •Theophylline (for asthma). •Insulin
Drug Pregnancy Interaction Talk to your doctor before taking this medicine if you are pregnant, might become pregnant or are breast-feeding.
Drug Breast feeding Interaction Talk to your doctor before taking this medicine if you are pregnant, might become pregnant or are breast-feeding.
Drug Machinery Interaction •Your medicine is not likely to affect you being able to drive or use any tools or machines. However, it is best to wait to see how your medicine affects you before trying these activities. •If you feel dizzy or tired when taking this medicine, do not drive or use any tools or machines
Drug More Information If you frequently drink a lot of alcohol, talk to your doctor before having this medicine. This is because alcohol can affect how the medicine works. If you go into hospital to have an operation, tell the anaesthetist or medical staff that you are taking Propranolol hydrochloride. This is because you can get low blood pressure (hypotension) if you are given certain anaesthetics while you are taking Propranolol hydrochloride.
How to take the Medicine
Consumption Info Propranolol hydrochloride contain microcrystalline cellulose and titanium dioxide. These may cause a problem in a very small number of people who are sensitive to them
Drug quanitty High blood pressure (hypertension): the usual dose is a day. Your doctor may decide to increase this dose. •Chest pain (angina): the usual dose is to 240 mg a day. •To prevent migraine: the usual dose is to 240 mg a day. •Essential tremor: the usual dose is to 240 mg a day. •Anxiety: the usual dose is to a day. •Thyroid conditions (such as thyrotoxicosis): the usual dose is to 240 mg a day. •Bleeding in the food pipe (oesophagus) caused by high blood pressure in the liver: the usual dose is to 320 mg a day. Elderly people If you are an elderly person, your doctor may decide to start you on a lower dose. Children Your medicine must not be given to children
Drug Dose Always take Propranolol hydrochloride exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. •Your doctor will tell you how many to take each day and when to take them. Read the label on the carton to remind you what the doctor said. •Swallow your Propranolol hydrochloride with a drink of water. Swallow whole. Do not chew.
Excess Drug Consumption If you take more Propranolol hydrochloride than prescribed by your doctor, talk to a doctor or go to a hospital straight away. Take the medicine pack with you so that the can be identified.
Forgot Drug Consumption If you forget to take a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.
Stop Drug Consumption Do not stop taking Propranolol hydrochloride without talking to your doctor. In some cases, you may need to stop taking it gradually.
Possible Side Effects
General Information •Diarrhoea. •Feeling sick (nausea). •Being sick (vomiting).
Common Drug Side Effects •You may notice that your pulse rate becomes slower while you are taking the This is normal, but if you are concerned please tell your doctor about it. •Cold hands and feet. •Numbness and spasm in your fingers which is followed by warmth and pain (Raynaud’s disease). •Disturbed sleep or nightmares. •Feeling tired
Rare Drug Side Effects •Heart block (which may cause an abnormal heart beat, dizziness,tiredness or fainting). •Dizziness, particularly on standing up. •Thinning of your hair. •Mood changes. •Feeling confused. •Memory loss. •Changes in personality (psychoses). •Hallucinations. •Tingling of your hands. •Disturbances of vision. •Dry eyes. •Skin rash. •Reduced numbers of platelets in your blood which may make you bruise more easily. •Purplish marks on your skin.
Very Rare Drug Side Effects •Severe muscle weakness (myasthenia gravis). •Changes to some of the cells or other parts of your blood. Your doctor may take blood samples every so often to check whether Propranolol hydrochloride has had any effect on your blood. •Low levels of sugar in the blood (hypoglycaemia). This can happen in people with or without diabetes.This includes elderly people, people on artificial kidneys (haemodialysis) or people taking medicines for diabetes. It may also happen if you are fasting or in people with a long-term liver disease.
Drug Side Effects Symptoms If you have any of the following conditions,they may get worse when you start to take your medicine. This happens rarely affecting less than 1 in 1,000 people. •Psoriasis (a skin condition). •Being short of breath or having swollen ankles (if you have heart failure). •Asthma or breathing problems. •Poor circulation. Do not be concerned by this list of side effects. You may not get any of them. If any of the side effects get serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist
How to Store the Medicine
How to Store the Medicine •Keep your medicine in a safe place where children cannot see or reach it. Your medicine could harm them. •Do not store above 25°C. Protect your medicine from light and moisture. Store your in the original package. Keep the calendar pack in the carton. •Do not use your after the expiry date which is stated on the carton.The expiry date refers to the last day of that month. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines that are no longer required.These measures will help to protect the environment

FLUNARIZINE

Information for patients
Drug Information Flunarizine is used to prevent migraine headaches with or without aura (warning signs that occur before the headache begins). This medication should not be used for treatment of acute migraine headaches (headaches that have already started). Flunarizine helps to reduce the frequency of migraine attacks and, to a lesser extent, the severity of the attacks. Flunarizine does not appear to have an effect on how long attacks last. The effect of flunarizine may not be seen for several weeks. Do not stop taking the medication due to lack of effect within the first six to eight weeks.
Drug Alert
Alert Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Before Consuming the Medicine
Avoid Drug an allergy to flunarizine or to any of the ingredients of the medication a history of depression a history of involuntary movement disorders (extrapyramidal symptoms)
Drug Special Care Depression: If you experience depression (such as depressed thoughts or mood, lack of interest in normal activities, sleep changes, or extreme fatigue), contact your doctor or health care professional immediately. Drowsiness/reduced alertness: Do not operate vehicles or equipment until you know how flunarizine affects you. Avoid drinking alcohol, since it can add to the potential drowsiness caused by flunarizine. Liver problems: Tell your doctor if you have ever had any liver problems. Pregnancy: There is little information concerning the use of this medication during pregnancy. Discuss the risks and benefits with your doctor. Breast-feeding: Flunarizine passes into breast milk. It should not be used by nursing women. Children: The safety and effectiveness of this medication has not been established for use by children less than 18 years old. Seniors: The effectiveness of this medication for use by seniors has not been established.
Drug Drug Interactions There may be an interaction between flunarizine and any of the following: alcohol anticonvulsants tranquilizers If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to: stop taking one of the medications, change one of the medications to another, change how you are taking one or both of the medications, or leave everything as is. An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed. Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
Drug Pregnancy Interaction There is little information concerning the use of this medication during pregnancy. Discuss the risks and benefits with your doctor.
Drug Breast feeding Interaction Flunarizine passes into breast milk. It should not be used by nursing women.
Drug Machinery Interaction no data available
Drug More Information no data available
How to take the Medicine
Consumption Info Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Drug quanitty The recommended adult dose of flunarizine is 10 mg daily
Drug Dose The recommended adult dose of flunarizine is 10 mg daily taken in the evening with or without food. Those who have side effects may find 5 mg daily in the evening to be effective.
Excess Drug Consumption Contact the emergency immedieatly
Forgot Drug Consumption If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice
Stop Drug Consumption Do not stop taking this medication without consulting your doctor.
Possible Side Effects
General Information bleeding, tender, or swollen gums breathing difficulty, coughing, or wheezing chest pain (may appear about 30 minutes after medication is taken) depression face appearing "mask-like" fainting irregular or fast, pounding heartbeat loss of balance control shuffling walk skin rash stiffness of the arms or legs swelling of the ankles, feet, or lower legs trembling and shaking of the hands and fingers trouble speaking or swallowing unusual secretion of breast milk
Common Drug Side Effects drowsiness constipation diarrhea dizziness or lightheadedness dryness of the mouth flushing and feeling of warmth headache increased appetite or weight gain nausea unusual tiredness or weakness
Rare Drug Side Effects no data available
Very Rare Drug Side Effects no data available
Drug Side Effects Symptoms no data available
How to Store the Medicine
How to Store the Medicine Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

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