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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Laretol Capsule is used to treat low blood calcium levels. It contains Calcitriol, which raises Vitamin D levels and thereby increases calcium levels in the blood. In some cases, this medicine may cause side effects such as stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, and headache. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

CALCITRIOL-0.25MCG

Manufacturer/Marketer :

La Renon Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Laretol Capsule

Laretol Capsule belongs to a group of medicines called 'vitamin D metabolites' primarily used to treat low blood calcium levels. Laretol Capsule effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Laretol Capsule can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Laretol Capsule is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

Laretol Capsule contains Calcitriol (Vitamin D3); it is used to prevent or treat a calcium deficiency. It is an essential nutrient to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine.

Take Laretol Capsule as prescribed by your doctor. Depending on your medical condition, you are advised to take Laretol Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Laretol Capsule can cause side effects like constipation, stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Laretol Capsule do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

If you are known to be allergic to Laretol Capsule or its inactive components, please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Laretol Capsule . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Laretol Capsule may pass into the breast milk. Hence, breastfeeding mothers need to seek medical advice before starting Laretol Capsule . Do not take Laretol Capsule if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Inform your doctor if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance.

Uses of Laretol Capsule

Laretol Capsule is used to treat Osteoporosis (weak and brittle bones), Osteomalacia/rickets (weak bones), Hypoparathyroidism (low levels of parathyroid hormone), and Latent tetany (a muscle disease with low blood calcium levels).

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Laretol Capsule effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Laretol Capsule can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Laretol Capsule is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.

How Laretol Capsule Works

Laretol Capsule contains Calcitriol (Vitamin D3); it is used to prevent or treat a calcium deficiency. It is an essential nutrient to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine.

Storage

Store in a cool and dry place away from sunlight
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Side effects of Laretol Capsule
  • Stay hydrated by drinking plenty of water.
  • Avoid dairy product such as cheese, milk, yogurt and ice cream.
  • Maintain healthy weight and exercise daily.
  • Following a low-calcium diet can help reduce hypercalcemia symptoms.
  • Reduce sodium intake to minimize calcium excretion in urine.
  • Limit animal protein consumption to decrease urinary calcium levels.
  • Increase fluid intake by drinking plenty of water to dilute urine.
  • Moderate calcium intake based on individual needs, avoiding drastic restriction.
  • Limit oxalate-rich foods like spinach and chocolate to minimize kidney stone formation.
  • Stay hydrated by drinking plenty of water.
  • Consider reducing vitamin D supplementation if excessive intake is contributing to hypercalciuria.
  • Regularly monitor urine calcium levels through 24-hour urine tests.
  • Always seek guidance from a healthcare expert prior to implementing substantial changes to your diet or lifestyle routine.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

What if I have taken an overdose of Laretol Capsule

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include feeling tired, difficulty thinking clearly, loss of appetite, nausea, vomiting, constipation, increased thirst, increased urination, weight loss, weakness, headache, upset stomach, dry mouth, muscle or bone pain, metallic taste in the mouth, difficult or painful urination, changes in vision, hallucination (seeing things or hearing voices that do not exist), fever or chills, stomach pain, pale/fatty stools, yellowing of the skin or eyes, runny nose, decreased sexual desire, and irregular heartbeat. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Before taking Laretol Capsule , inform your doctor if you are undergoing hemodialysis due to kidney problems and have a stent in the heart. Laretol Capsule may alter calcium levels, so it is recommended to monitor calcium levels in the blood and urine regularly. Inform your doctor immediately if you notice fever, increased thirst and urination, dehydration, bedwetting, constipation, and stomach pain, as they may sign very high calcium levels in your blood. Pregnant or breastfeeding women should consult their doctor before taking Laretol Capsule . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Laretol Capsule may pass into the breast milk. Hence, breastfeeding mothers need to seek medical advice before starting Laretol Capsule . Do not take Laretol Capsule if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).

Drug-Drug Interactions

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CalcitriolDigitoxin
Severe
CalcitriolOrlistat
Severe

Drug-Drug Interactions

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CalcitriolDigitoxin
Severe
How does the drug interact with Laretol Capsule:
Co-administration of Laretol Capsule with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Laretol Capsule can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
CalcitriolOrlistat
Severe
How does the drug interact with Laretol Capsule:
Co-administration of Orlistat with Laretol Capsule may reduce the levels of Laretol Capsule which can lead to low treatment outcomes.

How to manage the interaction:
Although there is an interaction, Laretol Capsule can be taken with Orlistat when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
CalcitriolDoxercalciferol
Severe
How does the drug interact with Laretol Capsule:
Co-administration of Doxercalciferol and Laretol Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Doxercalciferol with Laretol Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolIsoniazid
Severe
How does the drug interact with Laretol Capsule:
Co-administration of Isoniazid with Laretol Capsule may decrease the effects of Laretol Capsule.

How to manage the interaction:
Although there is an interaction, Laretol Capsule can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
CalcitriolMetolazone
Severe
How does the drug interact with Laretol Capsule:
Co-administration of Metolazone with Laretol Capsule can cause blood calcium levels to become too high.

How to manage the interaction:
Although there is an interaction, Laretol Capsule can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
CalcitriolFosphenytoin
Severe
How does the drug interact with Laretol Capsule:
Taking Laretol Capsule with Fosphenytoin can reduce the levels and efficacy of Laretol Capsule.

How to manage the interaction:
Taking Laretol Capsule with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolRifapentine
Severe
How does the drug interact with Laretol Capsule:
Co-administration of Rifapentine with Laretol Capsule may decrease the effects of Laretol Capsule.

How to manage the interaction:
Although there is an interaction, Laretol Capsule can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.
CalcitriolCarbamazepine
Severe
How does the drug interact with Laretol Capsule:
Co-administration of Laretol Capsule with Carbamazepine may decrease the effects of Laretol Capsule.

How to manage the interaction:
Although there is an interaction, Laretol Capsule can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
CalcitriolErgocalciferol
Severe
How does the drug interact with Laretol Capsule:
Co-administration of Ergocalciferol and Laretol Capsule are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Co-administration of Ergocalciferol with Laretol Capsule can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolDihydrotachysterol
Severe
How does the drug interact with Laretol Capsule:
Co-administration of Laretol Capsule with Dihydrotachysterol can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Dihydrotachysterol with Laretol Capsule can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables daily.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Habit Forming

No

Therapeutic Class

MULTIMINERALS

Laretol Capsule Substitute

Substitutes safety advice
  • Rocaltrol 0.25 mcg Capsule 10's

    by Others

    30.92per tablet
  • Bio-D3 Capsule 10's

    by Others

    23.94per tablet
  • Actived 0.25 mcg Tablet 30's

    by Others

    9.90per tablet
  • Calcit SG Capsule 10's

    by Others

    12.20per tablet
  • Calci Capsule 10's

    by AYUR

    12.51per tablet
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence, it is advised to limit the alcohol intake while using Laretol Capsule .

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Pregnancy

Caution

Use higher doses of Laretol Capsule during pregnancy than the daily dietary allowance only when the doctor advises. Calcitriol in higher doses may harm the fetus. Your doctor will weigh the potential risks and benefits before prescribing Laretol Capsule .

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Breast Feeding

Caution

Consult your doctor before taking Laretol Capsule if you are breastfeeding. Laretol Capsule can pass into the breast milk. If Laretol Capsule is used during breastfeeding, please monitor the mother and the infant's serum calcium levels.

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Driving

Safe if prescribed

Laretol Capsule may not affect your ability to drive.

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Liver

Caution

Before taking $ name, let your doctor know if you have any history of liver disease. Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.

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Kidney

Caution

It is advised to seek a doctor's advice before starting Laretol Capsule if you have kidney diseases like kidney stones or are undergoing dialysis. Calcitriol in Laretol Capsule increases inorganic phosphate levels in serum; hence, caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).

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Children

Caution

Laretol Capsule should be used with caution in children and only if prescribed by a doctor.

FAQs

Laretol Capsule belongs to a group of medicines called ‘vitamin D metabolites’ primarily used to treat low blood calcium levels. Laretol Capsule effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels).

Laretol Capsule contains calcitriol, which works by helping the body absorb more calcium from the diet. This helps to form healthy bones and reduce bone damage.

Laretol Capsule can cause kidney stones due to excess calcium deposition when used for a prolonged period. Please consult your doctor before taking Laretol Capsule as a daily supplement if you have any kidney problems or a history of kidney stones.

Laretol Capsule is used to increase low calcium levels in the body. Hence, it is not advised to use Laretol Capsule during hypercalcemia since it causes an overdose of calcium, leading to kidney stones and other effects.

Do not use Laretol Capsule if you are allergic to any of the ingredients in Laretol Capsule . It is not recommended in hypercalcemia (high calcium levels), metastatic calcification (extra deposits of calcium in the body), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).

Country of origin

INDIA

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - LAR0021

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